ThomasPShanleyMDFCCM

PubMed

• 2 citations
  Aligning academic medicine within the healthcare system: the APS-SPR virtual chat series.
  Thomas Shanley, Allison Brashear, S Claiborne Johnston> ;Pediatric Research. 2023 Feb 1
• 1 citations
  Metformin alleviates lung-endothelial hyperpermeability by regulating cofilin-1/PP2AC pathway.
  M Rizwan Siddiqui, Narsa M Reddy, Hafeez M Faridi, Mohd Shahid, Thomas P Shanley> ;Frontiers in Pharmacology. 2023 Jan 1
• 29 citations
  Robust genome editing in adult vascular endothelium by nanoparticle delivery of CRISPR-Cas9 plasmid DNA.
  Xianming Zhang, Hua Jin, Xiaojia Huang, Birendra Chaurasiya, Daoyin Dong, Thomas P Shanley, You-Yang Zhao> ;Cell Reports. 2022 Jan 4
• 18 citations
  Miniaturized wireless, skin-integrated sensor networks for quantifying full-body movement behaviors and vital signs in infants
  Hyoyoung Jeong, Sung Soo Kwak, Seokwoo Sohn, Jong Yoon Lee, Young Joong Lee, Megan K. O’Brien, Yoonseok Park, Raudel Avila, Jin-Tae Kim, Jae-Young Yoo, Masahiro Irie, ...> ;Proceedings of the National Academy of Sciences of the United States of America. 2021 Oct 26
• 3 citations
  Outcomes Associated with Early RBC Transfusion in Pediatric Severe Sepsis: A Propensity-Adjusted Multicenter Cohort Study.
  Jennifer A. Muszynski, Russell Banks, Ron W Reeder, Mark W. Hall, Robert A. Berg, Athena F. Zuppa, Thomas P. Shanley, Timothy T. Cornell, Christopher J. L. Newth, Murr...> ;Shock. 2021 Oct 8
• 8 citations
  Health-Related Quality of Life After Community-Acquired Septic Shock in Children With Preexisting Severe Developmental Disabilities.
  Kathleen L. Meert, Ron W Reeder, Aline B Maddux, Russell Banks, Robert A. Berg, Christopher J. L. Newth, Mark W. Hall, Michael W. Quasney, Joseph A. Carcillo, Patrick ...> ;Pediatric Critical Care Medicine. 2021 May 1
• Risk Factors for Mortality in Refractory Pediatric Septic Shock Supported with Extracorporeal Life Support.
  Jennifer K Workman, David K Bailly, Ron W Reeder, Heidi J Dalton, Robert A Berg, Thomas P Shanley, Christopher J L Newth, Murray M Pollack, David Wessel, Joseph Carcil...> ;ASAIO Journal. 2020 Nov 2
• 21 citations
  Surfactant Protein D Is Associated With Severe Pediatric ARDS, Prolonged Ventilation, and Death in Children With Acute Respiratory Failure
  Mary K. Dahmer, Heidi R. Flori, Anil Sapru, Joseph G Kohne, Heidi M. Weeks, Martha A. Q. Curley, Michael A. Matthay, Michael W. Quasney, Scot T. Bateman, M. D. Berg, S...> ;Chest. 2020 Apr 8
• 3 citations
  Association between time of day and CPR quality as measured by CPR hemodynamics during pediatric in-hospital CPR.
  Heather Wolfe, Ryan W. Morgan, Robert M. Sutton, Ron W Reeder, Kathleen L Meert, Murray M Pollack, Andrew R. Yates, John T. Berger, Christopher J. L. Newth, Joseph Car...> ;Resuscitation. 2020 Aug 1
• 32 citations
  Platelet Transfusion Practice and Related Outcomes in Pediatric Extracorporeal Membrane Oxygenation.
  Katherine Cashen, Heidi J. Dalton, Ron W Reeder, Arun Saini, Athena F. Zuppa, Thomas P. Shanley, Christopher J. L. Newth, Murray M Pollack, David L. Wessel, Joseph Car...> ;Pediatric Critical Care Medicine. 2020 Feb 1
• 12 citations
  The association of immediate post cardiac arrest diastolic hypertension and survival following pediatric cardiac arrest
  Alexis A. Topjian, Robert M. Sutton, Ron W Reeder, Russell Telford, Kathleen L. Meert, Andrew R. Yates, Ryan W. Morgan, John T. Berger, Christopher J. L. Newth, Joseph...> ;Resuscitation. 2019 Aug 1
• 13 citations
  Loss of myeloid-specific protein phosphatase 2A enhances lung injury and fibrosis and results in IL-10-dependent sensitization of epithelial cell apoptosis.
  Lei Sun, Elissa M Hult, Timothy T. Cornell, Kevin K. Kim, Thomas P. Shanley, Carol A. Wilke, Manisha Agarwal, Stephen J. Gurczynski, Bethany B. Moore, Mary K. Dahmer> ;American Journal of Physiology. Lung Cellular and Molecular Physiology. 2019 Jun 1
• 30 citations
  miR-144-mediated Inhibition of ROCK1 Protects against LPS-induced Lung Endothelial Hyperpermeability.
  M. Rizwan Siddiqui, Suhail Akhtar, Mohd Shahid, Mohammad Tauseef, Kelli McDonough, Thomas P. Shanley> ;American Journal of Respiratory Cell and Molecular Biology. 2019 Aug 1
• 39 citations
  Hemolysis During Pediatric Extracorporeal Membrane Oxygenation: Associations With Circuitry, Complications, and Mortality
  Heidi J. Dalton, Katherine Cashen, Ron W Reeder, Robert A. Berg, Thomas P. Shanley, Christopher J. L. Newth, Murray M. Pollack, David L. Wessel, Joseph A. Carcillo, Ri...> ;Pediatric Critical Care Medicine. 2018 Nov 1
• 44 citations
  Chest compression rates and pediatric in-hospital cardiac arrest survival outcomes.
  Robert M. Sutton, Ron W Reeder, William P. Landis, Kathleen L. Meert, Andrew R. Yates, John T. Berger, Christopher J. L. Newth, Joseph A. Carcillo, Patrick S. McQuille...> ;Resuscitation. 2018 Jul 18
• 31 citations
  RBC Transfusion Practice in Pediatric Extracorporeal Membrane Oxygenation Support.
  Jennifer A. Muszynski, Ron W Reeder, Mark W. Hall, Robert A. Berg, Thomas P. Shanley, Christopher J. L. Newth, Murray M. Pollack, David L. Wessel, Joseph A. Carcillo, ...> ;Critical Care Medicine. 2018 Jun 1
• 22 citations
  Acquired infection during neonatal and pediatric extracorporeal membrane oxygenation.
  Katherine Cashen, Ron W Reeder, Heidi J. Dalton, Robert A. Berg, Thomas P. Shanley, Christopher J. L. Newth, Murray M. Pollack, David L. Wessel, Joseph A. Carcillo, Ri...> ;Perfusion. 2018 Apr 11
• 40 citations
  Hyperoxia and Hypocapnia During Pediatric Extracorporeal Membrane Oxygenation: Associations With Complications, Mortality, and Functional Status Among Survivors*
  Katherine Cashen, Ron W Reeder, Heidi J. Dalton, Robert A. Berg, Thomas P. Shanley, Christopher J. L. Newth, Murray M. Pollack, David L. Wessel, Joseph A. Carcillo, Ri...> ;Pediatric Critical Care Medicine. 2018 Mar 1
• 29 citations
  Variability in Usual Care Mechanical Ventilation for Pediatric Acute Respiratory Distress Syndrome: Time for a Decision Support Protocol?
  Christopher J. L. Newth, Katherine A. Sward, Robinder G. Khemani, Kent Page, Kathleen L. Meert, Joseph A. Carcillo, Thomas P. Shanley, Frank W. Moler, Murray M. Pollac...> ;Pediatric Critical Care Medicine. 2017 Nov 1
• 7 citations
  Interaction Between 2 Nutraceutical Treatments and Host Immune Status in the Pediatric Critical Illness Stress-Induced Immune Suppression Comparative Effectiveness Trial.
  Joseph A. Carcillo, J. Michael Dean, Richard Holubkov, John T. Berger, Kathleen L. Meert, Kanwaljeet J. S. Anand, Jerry J. Zimmerman, Christopher J. L. Newth, Rick Har...> ;JPEN. Journal of Parenteral and Enteral Nutrition. 2017 Nov 1
• 5 citations
  Cognitive Development One Year After Infantile Critical Pertussis.
  John T Berger, Michele E Villalobos, Amy E Clark, Richard Holubkov, Murray M Pollack, Robert A Berg, Joseph A Carcillo, Heidi Dalton, Rick Harrison, Kathleen L Meert, ...> ;Pediatric Critical Care Medicine. 2018 Feb 1
• 8 citations
  Potential Acceptability of a Pediatric Ventilator Management Computer Protocol
  Katherine A. Sward, Christopher J. L. Newth, Robinder G. Khemani, Kent Page, Kathleen L. Meert, Joseph A. Carcillo, Thomas P. Shanley, Frank W. Moler, Murray M. Pollac...> ;Pediatric Critical Care Medicine. 2017 Nov 1
• 42 citations
  Functional Status of Neonatal and Pediatric Patients After Extracorporeal Membrane Oxygenation.
  Katherine Cashen, Ron W Reeder, Heidi J. Dalton, Robert A. Berg, Thomas P. Shanley, Christopher J. L. Newth, Murray M. Pollack, David L. Wessel, Joseph A. Carcillo, Ri...> ;Pediatric Critical Care Medicine. 2017 Jun 1
• 44 citations
  Education and training of clinical and translational study investigators and research coordinators: A competency-based approach.
  Nancy A. Calvin-Naylor, Carolynn Thomas Jones, Michelle M. Wartak, Karen Blackwell, Jonathan M. Davis, Ruthvick Divecha, Edward F. Ellerbeck, Karl Kieburtz, Margaret J...> ;Journal of Clinical and Translational Science. 2017 Jan 13
• 195 citations
  Factors Associated with Bleeding and Thrombosis in Children Receiving Extracorporeal Membrane Oxygenation.
  Heidi J. Dalton, Ron W Reeder, Pamela Garcia-Filion, Richard Holubkov, Robert A. Berg, Athena F. Zuppa, Frank W. Moler, Thomas P. Shanley, Murray M. Pollack, Christoph...> ;American Journal of Respiratory and Critical Care Medicine. 2017 Sep 15
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Journal Articles

• Tristetraprolin Mediates Radiation-induced TNF-alpha Production in Lung Macrophages  
  Ray D, Shukla S, Helman A, Ramanand SG, Tran L, Bassetti M, Paulsen M, Sun L, Shanley TP, Ljungman M, Nyati MK, Zhang M, Lawrence TS, PLoS One, 1/1/2013
• Ratio of PICU Versus Ward Cardiopulmonary Resuscitation Events Is Increasing  
  Berg RA, Sutton RM, Holubkov R, Nicholson CE, Dean JM, Harrison R, Heidemann S, Meert K, Newth C, Moler F, Pollack M, Dalton H, Doctor A, Wessel D, Berger J, Shanley T..., Crit Care Med, 1/1/2013
• Clinical Implications and Molecular Mechanisms of Immunoparalysis following Cardiopulmonary Bypass  
  Cornell TT, Sun L, Hall MW, Gurney JG, AshbrookMJ, Ohye RG, Shanley TP, J Thorac Cardiovasc Surg, 1/1/2012
• Tracking the Impact of the National Institutes of Health Clinical and Translational Science Awards on Child Health Research: Developing and Evaluating a Measurement St...  
  Huskins WC, Sullivan CD, Wang J, Aitken M, Alexander SR, Epstein L, Hoberman A, Neufeld E, Philipps A, Shanley TP, Szilagyi P, Purucker M, Barkin SL, Pediatr Res, 1/1/2012
• Preparedness of the CTSA's Structural and Scientific Assets to Support the Mission of the National Center for Advancing Translational Sciences (NCATS)  
  CTSA Principal Investigators, Shamoon H, Center D, Davis P, Tuchman M, Ginsberg H, Califf R, Stephens D, Mellman T, Verbalis J, Nadler L, Shekhar A, Ford D, Rizza R, S..., Clin Transl Sci, 1/1/2012
• Inpatient Health Care Utilization for Children Dependent on Long-term Mechanical Ventilation  
  Benneyworth BD, Gebremariam A, Clark SJ, Shanley TP, Davis MM, Pediatrics, 6/1/2011
• Weight-based Determination of Fluid Overload Status and Mortality in Pediatric Intensive Care Unit Patients Requiring Continuous Renal Replacement Therapy  
  Selewski DT, Cornell TT, Lombel RM, Blatt NB, Han YY, Mottes T, Kommareddi M, Kershaw DB, Shanley TP, Heung M, Intensive Care Med, 4/30/2011
• The Accreditation Council for Graduate Medical Education Proposed Work Hour Regulations  
  Goodman DM, Winkler MK, Fiser RT, Abd-Allah S, Mathur M, Rivero N, Weiss IK, Peterson B, Cornfield DN, Mink R, Nozik Grayck E, McCabe ME, Schuette J, Nares ..., Pediatr Crit Care Med, 1/1/2011
• Leukocyte Subset-derived Genomewide Expression Profiles in Pediatric Septic Shock  
  Wong HR, Freishtat RJ, Monaco M, Odoms K, Shanley TP, Ped Crit Care Med, 1/1/2010
• Mitogen Activated Protein Kinase Phosphatase 2 Regulates the Inflammatory Response in Sepsis  
  Cornell TT, Rodenhouse P, Cai Q, Sun L, Shanley TP, Infection and Immunity, 1/1/2010
• MAP Kinase Phosphatase (MKP)-1 and Septic Shock  
  Liu Y, Shanley TP, Journal of Organ Dysfunction, 1/1/2009
• Ceramide-dependent, PP2A Regulation of TNF-alphainduced IL-8 Production in Respiratory Epithelial Cells  
  Cornell TT, Hinkovska-Galcheva V, Sun L, Cai Q, Hershenson MB, Vanway S, Shanley TP, Am J Physiol Lung Cell Mol Physiol, 1/1/2009
• For the Genomics of Pediatric SIRS/Septic Shock Investigators Genomic Expression Profiling across the Pediatric Systemic Inflammatory Response Syndrome, ...  
  Wong HR, Cvijanovich N, Allen GL, Lin R, Anas N, Meyer K, Freishtat RJ, Monaco M, Odoms K, Sakthivel B, Shanley TP, Crit Care Med, 1/1/2009
• 2007 American College of Critical Care Medicine Clinical Practice Parameters for Hemodynamic Support of Pediatric and Neonatal Septic Shock  
  Brierley J, Choong K, Cornell T, Decaen A, Deymann A, Doctor A, Davis A, Duff J, Dugas MA, Duncan A, Evans B, Feldman J, Felmet K, Fisher G, Frankel L, Jef..., Crit Care Med, 11/28/2008
• Ceramide Kinase Promotes Ca2+ Signaling near IgG-opsonized Targets and Enhances Phagolysosomal Fusion in COS-1 Cells  
  Hinkovska-Galcheva VT, Clark A, Van Way SM, Huang JB, Hiraoka M, Abe A, Borofsky M, Kunkel RG, Shanley TP, Shayman JA, Lanni F, Petty HR, Boxer LA, J Lipid Res, 1/1/2008
• PP2A Regulates Upstream Members of the c-jun N-terminal Kinase Mitogen-activated Protein Kinase Signaling Pathway  
  Zhao B, Sun L, Haas M, Denenberg A, Wong HR, Shanley TP, SHOCK, 1/1/2008
• Do Outcomes Vary according to the Source of Admission to the Pediatric Intensive Care Unit  
  Odetola FO, Rosenberg AL, Davis MM, Clark SJ, Dechert RE, Shanley TP, Pediatr Crit Care Med, 1/1/2008
• GM-CSF-dependent Peritoneal Macrophage Responses Determine Survival in Experimentally-induced Peritonitis and Sepsis in Mice  
  Spight D, Trapnell B, Zhao B, Berclaz P, Shanley TP, SHOCK, 1/1/2008
• Extracorporeal Life Support for Severe Respiratory Failure in Children with Immune Compromised Conditions  
  Gupta M, Shanley TP, Moler FW, Ped Crit Care Med, 1/1/2008
• Validating the Genomic Signature of Pediatric Septic Shock  
  Cvijanovich N, Shanley TP, Lin R, Allen GL, Thomas NJ, Checchia P, Anas N, Freishtat RJ, Monaco M, Tagavilla MA, Odoms K, Sakthivel B, and Wong HR for the..., Physiological Genomics, 1/1/2008
• The Role of Sphingosine-1-phosphate and Ceramide-1-phosphate in Calcium Homeostasis  
  Hinkovska-Galcheva V, VanWay SM, Shanley TP, Kunkel RG, Curr Opin Investig Drugs, 1/1/2008
• Epstein-Barr Virus-Induced Hemophagocytic Lymphohistiocytosis and X-Linked lymphoproliferative Disease: A Mimicker of Sepsis in the Pediatric Intensive Ca...  
  Mischler M, Fleming GM, Shanley TP, et al, Pediatrics, 1/1/2007
• The Role of Phosphatase 2A on the Post-transcriptional Regulation of TNF Alpha Secretion in Alveolar Macrophages  
  Sun L, StoecklinG, Vanway SM, Hinkovska-Galcheva V, Guo R-F, Shanley TP, J Biol Chem, 1/1/2007
• Going Back for More: An Evaluation of Clinical Outcomes and Characteristics of Readmissions to a Pediatric Intensive Care Unit  
  Odetola FO, Shanley TP, Gurney JG, Clark SJ, Dechert RE, Freed GL, Davis MM, Pediatr Crit Care Med, 1/1/2007
• Genome Level Expression Profiles in Pediatric Septic Shock Indicate a Role for Altered Zinc Homeostasis in Poor Outcome  
  Wong HR, Shanley TP, Bhuvaneswari S, Cvijanovich N, Lin R, Allen GL, Thomas NJ, Doctor A, Kalyanaraman M, Tofil NM, Penfil S, Monaco M, Tagavilla MA, Odoms K, Dunsmore..., Physiol Genomics, 1/1/2007
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