TimiIEdekiMD

PubMed

• 37 citations
  Phase I Study Assessing the Pharmacokinetic Profile, Safety, and Tolerability of a Single Dose of Ceftazidime-Avibactam in Hospitalized Pediatric Patients.
  John S. Bradley, Jon Armstrong, Antonio Arrieta, Raafat Bishai, Shampa Das, Shirley F. Delair, Timi Edeki, William C. Holmes, Jianguo Li, Kathryn Moffett, Deepa Mukund...> ;Antimicrobial Agents and Chemotherapy. 2016 Oct 1
• 9 citations
  A Randomized, Phase I Study to Assess the Safety, Tolerability and Pharmacokinetics of Ceftazidime-Avibactam in Healthy Chinese Subjects.
  Jianguo Li, Maria Learoyd, Furong Qiu, LeiLei Zhu, Timi Edeki> ;Clinical Drug Investigation. 2016 Feb 1
• 28 citations
  Randomized pharmacokinetic and drug-drug interaction studies of ceftazidime, avibactam, and metronidazole in healthy subjects.
  Shampa Das, Jianguo Li, Jon Armstrong, Maria Learoyd, Timi Edeki> ;Pharmacology Research & Perspectives. 2015 Oct 1
• 94 citations
  Phase 1 study assessing the steady-state concentration of ceftazidime and avibactam in plasma and epithelial lining fluid following two dosing regimens
  David P. Nicolau, Leonard Siew, Jon Armstrong, James Li, Timi Edeki, Maria Learoyd, Shampa Das> ;The Journal of Antimicrobial Chemotherapy. 2015 Oct 1
• 27 citations
  Phase I study assessing the safety, tolerability, and pharmacokinetics of avibactam and ceftazidime-avibactam in healthy Japanese volunteers.
  Nobumitsu Tominaga, Timi Edeki, James Li, Maria Learoyd, M. René Bouw, Shampa Das> ;Journal of Infection and Chemotherapy. 2015 Aug 1
• 10 citations
  Evaluation of the pharmacokinetics and safety of single and multiple ceftaroline fosamil infusions in healthy Chinese and Western subjects
  Li Yang, Maria Sunzel, Peng Xu, Timi Edeki, David Wilson, Jianguo Li, Haiyan Li> ;International Journal of Clinical Pharmacology and Therapeutics. 2015 Aug 1
• 3 citations
  Safety, local tolerability and pharmacokinetics of ceftaroline fosamil administered in a reduced infusion volume
  Timi Edeki, Mirjana Kujacic, Helen Broadhurst, Jianguo Li, Maria Sunzel> ;British Journal of Clinical Pharmacology. 2014 Dec 1
• 24 citations
  Randomized, placebo-controlled study to assess the impact on QT/QTc interval of supratherapeutic doses of ceftazidime-avibactam or ceftaroline fosamil-avibactam.
  Shampa Das, Jon Armstrong, David Mathews, Jianguo Li, Timi Edeki> ;Journal of Clinical Pharmacology. 2014 Mar 1
• 116 citations
  International Transporter Consortium Commentary on Clinically Important Transporter Polymorphisms
  Kathleen M. Giacomini, Praveen Balimane, Sung Kweon Cho, Michael T. Eadon, Timi Edeki, Kathleen M. Hillgren, Huang Sm, Y. Sugiyama, Dietmar Weitz, Yujia Wen, Cindy Q. ...> ;Clinical Pharmacology and Therapeutics. 2013 Jul 1
• 5 citations
  PhRMA survey on the conduct of first-in-human clinical trials under exploratory investigational new drug applications.
  Adel H. Karara, Timi Edeki, James McLeod, Alfred Tonelli, John A. Wagner> ;Journal of Clinical Pharmacology. 2010 Apr 1
• 40 citations
  PhRMA white paper on ADME pharmacogenomics.
  J. Andrew Williams, Tommy B. Andersson, Tommy B. Andersson, Rebecca L. Blanchard, Martin O. Behm, Nadine Cohen, Timi Edeki, Monique A. Franc, Kathleen M. Hillgren, Kei...> ;Journal of Clinical Pharmacology. 2008 Jul 1
• 21 citations
  EFFECTS OF INDIVIDUAL GINSENOSIDES, GINKGOLIDES AND FLAVONOIDS ON CYP2C19 AND CYP2D6 ACTIVITY IN HUMAN LIVER MICROSOMES
  Nu He, Hong-Guang Xie, Xavier Collins, Timi I Edeki, Zhengyin Yan> ;Clinical and Experimental Pharmacology & Physiology. 2006 Sep 1
• Erythrocytosis in a scleroderma patient.
  Eric Mabo, Timi Edeki, Gloria Westney, James W Reed, Xiaoqing Guo> ;The Mount Sinai Journal of Medicine, New York. 2006 May 1
• 18 citations
  Evaluation of the potential for pharmacokinetic interaction between fenofibrate and ezetimibe: A phase I, open-label, multiple-dose, three-period crossover study in he...
  Linda E. Gustavson, Sarah M. Schweitzer, David A. Burt, Ramanuj Achari, Matthew J. Rieser, Timi Edeki, Titus Chira, H. Daniel Yannicelli, Maureen T. Kelly> ;Clinical Therapeutics. 2006 Mar 1
• 67 citations
  Organic anion transporting polypeptide 1B1 activity classified by SLCO1B1 genotype influences atrasentan pharmacokinetics.
  David A. Katz, Robert A. Carr, Dirk Grimm, Hao Xiong, Rhonda R. Holley-Shanks, Toby Mueller, Brenda F. Leake, Qiang Wang, Lixin Han, Perry G. Wang, Timi Edeki, Leonard...> ;Clinical Pharmacology and Therapeutics. 2006 Mar 1
• 10 citations
  A phase I multiple-dose escalation study characterizing pharmacokinetics and safety of ABT-578 in healthy subjects.
  Chetan S. Karyekar, Rajendra Pradhan, Tony Freeney, Qin Ji, Timi Edeki, Wenzi Chiu, Walid M. Awni, Charles Locke, Lewis B. Schwartz, Richard Granneman, Robert O'Dea> ;Journal of Clinical Pharmacology. 2005 Aug 1
• 61 citations
  The inhibitory effects of herbal components on CYP2C9 and CYP3A4 catalytic activities in human liver microsomes.
  Nu He, Timi Edeki> ;American Journal of Therapeutics. 2004 May 1
• 601 citations
  Depression as a risk factor for Alzheimer disease: the MIRAGE Study.
  Robert C. Green, L. Adrienne Cupples, Alex Kurz, Sanford Auerbach, Rodney C.P. Go, Dessa Sadovnick, Ranjan Duara, Walter A. Kukull, Helena C. Chui, Timi Edeki, Patrick...> ;Archives of Neurology. 2003 May 1
• 80 citations
  Association between apolipoprotein E genotype and Alzheimer disease in African American subjects.
  Neill R. Graff-Radford, Robert C. Green, Rodney C.P. Go, Mike Hutton, Timi Edeki, David Bachman, Jennifer Adamson, Patrick Griffith, Floyd B. Willis, Mary Williams, Yv...> ;Archives of Neurology. 2002 Apr 1
• 15 citations
  Inhibitory effects of H1-antihistamines on CYP2D6- and CYP2C9-mediated drug metabolic reactions in human liver microsomes.
  Nu He, Wen-Qi Zhang, Dolores C. Shockley, Timi Edeki> ;European Journal of Clinical Pharmacology. 2002 Jan 17
• 262 citations
  Risk of Dementia Among White and African American Relatives of Patients With Alzheimer Disease
  Robert C. Green, L. Adrienne Cupples, Rodney C.P. Go, Kelly S. Benke, Timi Edeki, Patrick Griffith, Mary Williams, Yvonne G. Hipps, Neill R. Graff-Radford, David Bachm...> ;JAMA. 2002 Jan 16
• 184 citations
  Identification of a null allele of CYP2C9 in an African-American exhibiting toxicity to phenytoin.
  Robert S. Kidd, Timothy B. Curry, Susan Gallagher, Timi Edeki, Joyce Blaisdell, Joyce A. Goldstein> ;Pharmacogenetics. 2001 Dec 1
• 1 citations
  Comparison of Plasma Protein Binding of Basic Drugs in Black and White Individuals.
  Timi Edeki, Betty Dillon-Moore, Nu He> ;American Journal of Therapeutics. 1996 Sep 1
• 25 citations
  Increased Baseline Sway Contributes to Increased Losses of Balance in Older People Following Triazolam
  Deborah W. Robin, Samer S. Hasan, Timi Edeki, Michael J. Lichtenstein, Richard Shiavi, Alastair J. J. Wood> ;Journal of the American Geriatrics Society. 1996 Mar 1
• 14 citations
  Phenytoin Disposition and Toxicity: Role of Pharmacogenetic and Interethnic Factors
  Timi I. Edeki, David A. Brase> ;Drug Metabolism Reviews. 1995 Jan 1
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