TimothyJBrownMD

PubMed

• The Clinical Implications of Reversions in Patients with Advanced Pancreatic Cancer and Pathogenic Variants in BRCA1, BRCA2, or PALB2 after Progression on Rucaparib.
  Arielle Yablonovitch, Jacob E Till, Jennifer Yen, Lesli A Kiedrowski, Ryan Hood, Mark H O'Hara, Ursina Teitelbaum, Erica L Carpenter, Katherine Nathanson, Susan M Domc...> ;Clinical Cancer Research. 2023 Dec 15
• Oral Carbon Monoxide Enhances Autophagy Modulation in Prostate, Pancreatic, and Lung Cancers.
  Jianling Bi, Emily Witt, Megan K McGovern, Arielle B Cafi, Lauren L Rosenstock, Anna B Pearson, Timothy J Brown, Thomas B Karasic, Lucas C Absler, Srija Machkanti, Han...> ;Advanced Science. 2024 Mar 1
• Advancements in Systemic Therapy for Pancreatic Cancer.
  Timothy J Brown, Kim A Reiss, Mark H O'Hara> ;American Society of Clinical Oncology Educational Book. American Society of Clinical Oncology. Annual Meeting. 2023 May 1
• 2 citations
  Nonsteroidal anti-inflammatory drugs as a targeted therapy for bone marrow failure in Ghosal hematodiaphyseal dysplasia.
  Timothy J Brown, Neil Barrett, Hu Meng, Emanuela Ricciotti, Ciara McDonnell, Andrew Dancis, Julianne Qualtieri, Garret A FitzGerald, Melanie Cotter, Daria V Babushok> ;Blood. 2023 Mar 30
• 2 citations
  Outcomes of hepatocellular carcinoma by etiology with first-line atezolizumab and bevacizumab: a real-world analysis.
  Timothy J Brown, Ronac Mamtani, Phyllis A Gimotty, Thomas B Karasic, Yu-Xiao Yang> ;Journal of Cancer Research and Clinical Oncology. 2023 Jun 1
• 6 citations
  Phase I Trial of Regorafenib, Hydroxychloroquine, and Entinostat in Metastatic Colorectal Cancer.
  Thomas B Karasic, Timothy J Brown, Charles Schneider, Ursina R Teitelbaum, Kim A Reiss, Tara C Mitchell, Ryan C Massa, Mark H O'Hara, Lisa DiCicco, Luis Garcia-Marcano...> ;The Oncologist. 2022 Sep 2
• 1 citations
  Accuracy of a Text Intervention to Minimize the Burden of Cancer Care Among Patients Treated With Immune Checkpoint Inhibitors.
  Erin M Bange, Kerry Coughlin, Wenrui Li, Elizabeth Moriarty, Timothy J Brown, Lawrence N Shulman, Ronac Mamtani> ;JAMA Network Open. 2022 Aug 1
• Challenges in the Management of Patients With HER2-Amplified Colorectal Cancer.
  Timothy J Brown, Ryan C Massa> ;JCO Oncology Practice. 2022 Aug 1
• 3 citations
  Trends of Clinical Outcomes of Patients with Advanced Hepatocellular Carcinoma Treated with First-Line Sorafenib in Randomized Controlled Trials.
  Timothy J Brown, Arjun Gupta, Ramy Sedhom, Muhammad S Beg, Thomas B Karasic, Mark Yarchoan> ;Gastrointestinal Tumors. 2022 Mar 1
• 12 citations
  PARP Inhibitors in Pancreatic Cancer.
  Timothy J Brown, Kim A Reiss> ;Cancer Journal. 2021 Dec 14
• 8 citations
  Immunotherapy Adverse Effects.
  Timothy J. Brown, Ronac Mamtani, Erin Bange> ;JAMA Oncology. 2021 Oct 28
• 4 citations
  Importance of addressing malnutrition in cancer and implementation of a quality improvement project in a gastrointestinal cancer clinic
  Nicholas Levonyak, Mary P Hodges, Nicole Haaf, Timothy J. Brown, Shelli Hardy, Verca Mhoon, Radhika Kainthla, Muhammad Shaalan Beg, Syed Mohammad Ali Kazmi> ;Nutrition in Clinical Practice. 2021 Aug 2
• A High-Value Care Initiative to Reduce the Use of Intravenous Magnesium Sulfate Through an Electronic Indication-Based Order Set
  Nimish N Shah, Chris Mathew, Timothy J. Brown, Albert Karam, Sandeep R Das> ;Joint Commission Journal on Quality and Patient Safety. 2021 Jun 22
• 2 citations
  Lessons from spending on megestrol for cancer cachexia.
  Timothy J. Brown, Sonal Gandhi, Thomas J. Smith, Arjun Gupta> ;Supportive Care in Cancer. 2021 Apr 24
• 8 citations
  Rates of appropriate laxative prophylaxis for opioid-induced constipation in veterans with lung cancer: a retrospective cohort study.
  Timothy J. Brown, Neil Keshvani, Arjun Gupta, Hui Yang, Deepak Agrawal, Tri Le, David E. Gerber, Carlos A. Alvarez> ;Supportive Care in Cancer. 2020 Mar 2
• 29 citations
  Management of Cancer Therapy–Associated Oral Mucositis
  Timothy J. Brown, Arjun Gupta> ;JCO Oncology Practice. 2020 Feb 3
• 6 citations
  Improving the Time to Activation of New Clinical Trials at a National Cancer Institute-Designated Comprehensive Cancer Center.
  Erin Fenske Williams, Timothy J. Brown, Patrice Griffith, Asal Rahimi, Rhonda Oilepo, Hans J. Hammers, Theodore W. Laetsch, Penny Currykosky, Susan Partridge, Muhammad...> ;JCO Oncology Practice. 2020 Jan 16
• 22 citations
  Sphingolipid metabolism determines the therapeutic efficacy of nanoliposomal ceramide in acute myeloid leukemia
  Brian M. Barth, Weiyuan Wang, Paul T. Toran, Todd E. Fox, Charyguly Annageldiyev, Regina M. Ondrasik, Nicole R. Keasey, Timothy J Brown, Viola Devine, Emily Sullivan, ...> ;Blood Advances. 2019 Sep 10
• 58 citations
  Management of low-grade glioma: a systematic review and meta-analysis.
  Timothy J. Brown, Daniela A. Bota, Martin J. van den Bent, Paul D. Brown, Elizabeth A. Maher, Dawit Aregawi, Linda M. Liau, Jan C. Buckner, Michael Weller, Mitchel S. ...> ;Neuro-Oncology Practice. 2019 Jul 27
• 9 citations
  Reducing Hospitalizations: Institution of Outpatient Infusional EPOCH-Based Chemotherapy at a Safety Net Hospital.
  Neil Keshvani, Mary Hon, Arjun Gupta, Timothy J. Brown, Lonnie Roy, Eileen Marley, Sandy Lindsey, David H. Johnson, Navid Sadeghi, Hsiao C. Li> ;Journal of Oncology Practice. 2019 Jun 17
• 4 citations
  Dissemination of Information on Neutropenic Diet by Top US Cancer Centers: In-line with the Evidence?
  Timothy J. Brown, Dhruvika Mukhija, Naveen Premnath, Anand Venkatraman, Sajan Jiv Singh Nagpal, Arjun Gupta> ;Nutrition and Cancer. 2019 May 2
• Promoting High-Value Change by Addressing the Structure of Order Sets: Lessons From the Cardiac Catheterization Lab.
  Nagendra R. Pokala, Shruti Singh, Gene Hu, Timothy J. Brown, Ambarish Pandey, Sandeep R Das, Arjun Gupta> ;American Journal of Medical Quality. 2019 May 1
• Finding the Magic in Magic Mouthwash-Reply.
  Angad S. Uberoi, Timothy J. Brown, Arjun Gupta> ;JAMA Internal Medicine. 2019 May 1
• 32 citations
  Chemotherapy-Induced Peripheral Neuropathy.
  Timothy J. Brown, Ramy Sedhom, Arjun Gupta> ;JAMA Oncology. 2019 May 1
• 1 citations
  Myopathy in a 61-year-old Hispanic man
  Gary Parizher, Timothy J. Brown, Mary Hon, Elena K. Joerns, Yu Zuo> ;BMJ Case Reports. 2019 Apr 1
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Journal Articles

• Promoting High-Value Change by Addressing the Structure of Order Sets: Lessons From the Cardiac Catheterization Lab  
  Pokala, N, Singh, S, Hu, G, Brown, TJ, Pandey, A, Das, SR, Gupta, A., American Journal of Medical Quality, 9/10/2018
• Management of low-grade glioma: a systematic review and meta-analysis  
  Brown, TJ, Bota, DA, van Den Bent, MJ, Brown, PD, Maher, E, Aregawi, D, Liau, LM, Buckner, JC, Weller, M, Berger, MS, Glantz, M., Neuro-Oncology Practice, 8/18/2018
• Combinatorial Efficacy of 7,8-Benzoflavone and Liposomal Ceramide in Acute Myeloid Leukemia.  
  Barth, BM, Brown, TJ, Adams, MT, Garcia, AM, Fisher, LN, Fritz, JL, Beck, AJ, McGill, CM, Kester, MC, Tran, MA, Claxton, DF, Journal of Leukemia, 9/23/2014
• Therapeutic combination of nanoliposomal safingol and nanoliposomal ceramide for acute myeloid leukemia  
  Brown, T.J., Garcia, A.M., Kissinger, L.N., Shanmugavelandy, S.S., Wang, X., Cabot, M.C., Kester, M.L., Claxton, D.F., and Barth, B.M., Journal of Leukemia, 4/26/2013
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Abstracts/Posters

• Better in the Bucket: Extensive Resection Improves Survival in Glioblastoma - a Systematic Review and Meta-Analysis of the World’s Literature
  Brown, T.J., Brennan, M.C., Church, E.W., Brandmeir, N.J., Rakszawski, K., Dima, S., Li, M., Rizk, E.B., Sawaya, R., Glantz, M., the 20th Annual Society for Neuro-Oncology Scientific Meeting, San Antonio, TX, 11/21/2015
• Defining the Role of Prophylactic Cranial Irradiation in NSCLC: a Systematic Review and Meta-Analysis of the World’s Literature
  Brown, T.J., Brennan, M.C., Mehta, M.P., Glantz, M., 20th Annual Society for Neuro-Oncology Scientific Meeting, San Antonio, 11/20/2015
• Effect of Extent of Resection on Survival in High Grade Glioma: A Systematic Review and Meta-analysis.
  Brown, T.J., Brennan, M.C., Church, E.C., Brandmeir, N., Rakszawski, K., Rizk, E., Glantz, M., 102nd Scientific Meeting of the Pennsylvania Neurosurgical Society, Hershey, PA, 7/10/2015
• Target wise and pound foolish: A simple technique to evaluate the trade-off between economic burden and clinical benefit of monoclonal antibodies
  Brennan, M. Brown, T.J., Koller, K., Cygan, P., Vasekar, M., Sivik, J., Glantz, M, 2015 ASCO Annual Meeting, Chicago, Il, 6/1/2015
• Defining the role of prophylactic cranial irradiation in NSCLC: a review and meta-analysis of the literature
  Brown, T.J., Brennan, M., Glantz, M., 2015 ASCO Annual Meeting (Online Only), Chicago, Il, 6/1/2015
• Improving the Anti-AML Efficacy of Liposomal Ceramide by Targeting Sphingolipid Metabolism.
  Brown, T.J., Garcia, A.M., Tan, S., Kissinger, L.N., Cabot, M.C., Feith, D.J., Claxton, D.F., Barth, B.M., Penn State College of Medicine Class of 2015 Medical Student Research Symposium, Hershey, PA, 5/13/2015
• Target wise and pound foolish: A simple technique to evaluate the trade-off between economic burden and clinical benefit of monoclonal antibodies.
  Brennan, M. Koller, K., Brown, T.J., Vasekar, M., Cygan, P., Sivik, J., Glantz, M, 7th Annual Resident/Fellow Research Day, Hershey, PA, 5/7/2015
• As Sweet as Pie: Blueberry Extracts as Therapy for Acute Myeloid Leukemia
  Brown, TJ, McGill, CM, Fisher, LN, Chen, YY, Shanmugavelandy, SS, Mangum, SJ, Dunlap, KL, Lila, MA, Kester, MC, Claxton, DF, Barth, BM, PA Eastern Region ACP Abstract Competition, Harrisburg, PA, 10/2014
• Improving the Anti-AML Efficacy of Liposomal Ceramide by Targeting Sphingolipid Metabolism
  Brown, T.J., Garcia, A.M., Tan, S., Kissinger, L.N., Cabot, M.C., Feith, D.J., Barth, B.M., Claxton, D.F, 2013 Annual Meeting of the AACR, Washington, DC, 4/2013
• Nutraceutical Intervention Targets NADPH Oxidase-Mediated Development and Progression of Acute Myeloid Leukemia
  Barth, B.M., Cheng, Y.Y., Brown, T.J., Claxton, D.F., Keystone Symposia on Molecular and Cellular Biology, Steamboat Springs, CO, 1/2013
• Enhancing Ceramide Cytotoxicity in Acute Myelogenous Leukemia.
  Brown, T.J., Claxton, D.F., Barth, B.M., Annual Meeting of the American Society of Hematology (Online Only), Atlanta, GA, 12/2012
• Metabolic Changes in Ovarian Cancer Progression and Mediation by Sphingosine: the MOSE Model
  Anderson, A.S., Roberts, P.C., Frisard, M.I., Brown, T., Hulver, M.W., and Schmelz, E.M., Virginia Tech Cancer Research Symposium, Blacksburg, VA, 4/2011
• Metabolic changes in ovarian cancer progression and mediation by sphingosine: the MOSE model
  Anderson, A.S., Roberts, P.C., Frisard, M.I., Brown, T., Hulver, M.W., and Schmelz, E.M., Annual Meeting of the AACR, Orlando, FL, 4/2011
• The Effect of Sphingosine on Lipid Metabolism and Cholesterol Synthesis Enzyme Transcription.
  Brown, T.J., Creekmore, A.L., Roberts, P.C., and Schmelz, E.M., USDA Summer Scholars Symposium, Blacksburg, VA, 7/2010
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Lectures

• Association of anticonvulsant prophylaxis in patients with primary and metastatic brain tumors and 1-year overall survival: A systematic review and meta-analysis. 
  2018 ASCO Annual Meeting - Chicago, Illinois - 06/2/2018