ToddOMcKinleyMD

Orthopaedic Surgery • Indianapolis, IN

Orthopedic Sports Medicine, Orthopedic Trauma, Pediatric Orthopedics

IU Health Physicians Orthopedics & Sports Medicine; Trauma, Orthopedic Surgery

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Office
1801 N Senate Blvd
Suite 535
Indianapolis, IN 46202
Phone+1 317-963-1950

Fax+1 317-963-1955
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Education & Training

University of California Davis HealthResidency, Orthopaedic Surgery, 1992 - 1997
University of Minnesota Medical SchoolClass of 1992

Certifications & Licensure

CA State Medical License 1994 - Present
IN State Medical License 2013 - 2023
IA State Medical License 1999 - 2014
MD State Medical License 1998 - 1999
American Board of Orthopaedic Surgery Orthopaedic Surgery

Clinical Trials

A Multicenter Randomized Trial Comparing IM Nails and Plate Fixation in Proximal Tibial Fractures Start of enrollment: 2007 Feb 01
Completed
Not Applicable
rhBMP-2 Versus Autograft in Critical Size Tibial Defects Start of enrollment: 2011 Aug 01
Terminated
Phase 4
Assessment of Fixation Strategies for Severe Open Tibia Fractures Start of enrollment: 2011 Jul 01
Completed
Phase 3
Improving Activity and Quality of Life Following Orthopaedic Trauma: The Trauma Collaborative Care Study (TCCS) Start of enrollment: 2013 Jul 01
Completed
Not Applicable
Streamlining Trauma Research Evaluation With Advanced Measurement Start of enrollment: 2014 Jan 01
Completed
Patient-Specific Precision Injury Signatures in Multiply Injured Orthopaedic Patients Start of enrollment: 2019 Mar 20
Active, not recruiting
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Publications & Presentations

PubMed

In situ forming biomaterials as muscle void fillers for the provisional treatment of volumetric muscle loss injuries.
Andrew Clark, Jonathan Kulwatno, Sergey S Kanovka, Todd O McKinley, Benjamin K Potter, Stephen M Goldman, Christopher L Dearth> ;Materials Today. Bio. 2023 Oct 1
Work Productivity Loss After Minimally Displaced Complete Lateral Compression Pelvis Fractures.
Natasha S McKibben, Nathan N O'Hara, Gerard P Slobogean, Greg E Gaski, Jason W Nascone, Marcus F Sciadini, Roman M Natoli, Todd McKinley, Walter W Virkus, Anthony T So...> ;Journal of Orthopaedic Trauma. 2023 Aug 9
Post-traumatic osteoarthritis: A review of pathogenic mechanisms and novel targets for mitigation.
Julian E Dilley, Margaret Anne Bello, Natoli Roman, Todd McKinley, Uma Sankar> ;Bone Reports. 2023 Jun 1
Minced muscle autografting improves bone healing but not muscle function in a porcine composite injury model.
Todd O McKinley, Roman N Natoli, Naveena B Janakiram, Stuart J Warden, Robyn K Fuchs, Zachary Gunderson, Nichlaus Diggins, Seungyup Sun, George Kolettis, Stephen M Gol...> ;Journal of Orthopaedic Research. 2023 Sep 1
2 citations
Single-cell RNAseq provides insight into altered immune cell populations in human fracture nonunions.
Keith G Avin, James M Dominguez 2nd, Neal X Chen, Takashi Hato, Jered J Myslinski, Hongyu Gao, Yunlong Liu, Todd O McKinley, Krista M Brown, Sharon M Moe, Roman M Natoli> ;Journal of Orthopaedic Research. 2023 May 1
1 citations
Risk factors for complications within 30 days of operatively fixed periprosthetic femur fractures.
Raveesh D Richard, Greg E Gaski, Hassan Farooq, Daniel J Wagner, Todd O McKinley, Roman M Natoli> ;Journal of Clinical Orthopaedics and Trauma. 2022 Aug 1
Application of Bayesian Methods to Help Interpret the VANCO Trial Results.
Nathan N O'Hara, Renan C Castillo, Anthony R Carlini, Manjari Joshi, Clinton K Murray, Lauren E Allen, Yanjie Huang, Joshua L Gary, Michael J Bosse, William T Obremske...> ;Journal of Orthopaedic Trauma. 2023 Jan 1
1 citations
Risk Factors for Composite Failure of Hip Dysplasia Treated With Periacetabular Osteotomy: A Minimum 10-Year Follow-up.
Michael C Willey, Robert W Westermann, Natalie Glass, Jessica E Goetz, Holly Aitken, Nastaran Fatemi, John Davison, Aspen Miller, Emily Parker, Catherine Fruehling, To...> ;The Journal of the American Academy of Orthopaedic Surgeons. 2022 Apr 15
Long-Term Consequences of Major Extremity Trauma: A Pilot Study.
Renan C Castillo, Anthony R Carlini, Trisha Chaffee, Michael J Bosse, Robert V O'Toole, Conor P Kleweno, Todd O McKinley, Julie Agel, Thomas F Higgins, Saam Morshed, E...> ;Journal of Orthopaedic Trauma. 2022 Jan 1
1 citations
Patient-Specific Precision Injury Signatures to Optimize Orthopaedic Interventions in Multiply Injured Patients (PRECISE STUDY).
Todd O McKinley, Greg E Gaski, Timothy R Billiar, Yoram Vodovotz, Krista M Brown, Eric A Elster, Greg M Constantine, Seth A Schobel, Henry T Robertson, Ashley D Meaghe...> ;Journal of Orthopaedic Trauma. 2022 Jan 1
1 citations
Cognitive-Behavioral-Based Physical Therapy for Improving Recovery After Traumatic Orthopaedic Lower Extremity Injury (CBPT-Trauma).
Kristin R Archer, Claudia A Davidson, Dana Alkhoury, Susan W Vanston, Tanisha L Moore, Andrea Deluca, Joshua F Betz, Richard E Thompson, William T Obremskey, Gerard P ...> ;Journal of Orthopaedic Trauma. 2022 Jan 1
Bone Morphogenetic Protein-2 Rapidly Heals Two Distinct Critical Sized Segmental Diaphyseal Bone Defects in a Porcine Model.
Todd O. McKinley, Paul Childress, Emily Jewell, Kaitlyn S. Griffin, Austin E. Wininger, Aamir Tucker, Adam Gremah, Michael K Savaglio, Stuart J. Warden, Robyn K. Fuchs...> ;Military Medicine. 2021 Sep 24
1 citations
Single-cell RNA sequencing of intramedullary canal tissue to improve methods for studying fracture repair biology
James M Dominguez, Sharon M. Moe, Neal X. Chen, Todd O. McKinley, Krista M Brown, Yunlong Liu, Hongyu Gao, Roman M. Natoli> ;Biotechniques. 2021 Aug 10
Polytraumatized Patient Lower Extremity Nonunion Development: Raw Data
Neil R. Sardesai, Greg E. Gaski, Zachary J. Gunderson, Connor M. Cunningham, James E. Slaven, Ashley D. Meagher, Todd O. McKinley, Roman M. Natoli> ;Data in Brief. 2021 Jun 25
4 citations
Base Deficit ≥ 6 within 24 h of Injury is a risk factor for fracture nonunion in the polytraumatized patient
Neil R. Sardesai, Greg E. Gaski, Zachary J. Gunderson, Connor M. Cunningham, James E. Slaven, Ashley D. Meagher, Todd O. McKinley, Roman M. Natoli> ;Injury. 2021 May 18
5 citations
The Use of Multiplexing to Identify Cytokine and Chemokine Networks in the Immune-Inflammatory Response to Trauma.
Jillian Bonaroti, Sultan S Abdelhamid, Upendra K. Kar, Jason L. Sperry, Ruben Zamora, Rami A. Namas, Todd O. McKinley, Yoram Vodovotz, Timothy R. Billiar> ;Antioxidants & Redox Signaling. 2021 May 19
9 citations
A Prospective Clinical Trial Comparing Surgical Fixation Versus Nonoperative Management of Minimally Displaced Complete Lateral Compression Pelvis Fractures.
Gerard P. Slobogean, Greg E. Gaski, Jason W. Nascone, Marcus F. Sciadini, Roman M. Natoli, Theodore T. Manson, Christopher T. LeBrun, Todd O. McKinley, Walter W Virkus...> ;Journal of Orthopaedic Trauma. 2021 Mar 16
1 citations
A Modified Levine Approach for Exposure of the Anterior Column, Anterior Wall, and Sacroiliac Joint: A Surgical Technique and a Case Series.
Yohan Jang, Walter W. Virkus, Todd O. McKinley> ;Journal of Orthopaedic Trauma. 2021 Mar 9
4 citations
Protective/reparative cytokines are suppressed at high injury severity in human trauma.
Jinman Cai, Todd O. McKinley, Isabel M. Billiar, Mazen S. Zenati, Greg E. Gaski, Yoram Vodovotz, Danielle S. Gruen, Timothy R. Billiar, Rami A. Namas> ;Trauma Surgery & Acute Care Open. 2021 Mar 2
4 citations
Polytrauma: update on basic science and clinical evidence
Aaron Nauth, Frank Hildebrand, Heather A. Vallier, Timothy A. Moore, Luke P. H. Leenen, Todd O. McKinley, Hans-Christoph Pape> ;OTA International. 2021 Feb 23
1 citations
Fixation using Alternative Implants for the Treatment of Hip Fractures (FAITH-2): The Exploratory Health-Related Quality of Life and Patient-Reported Functional Outcom...
Gerard P. Slobogean, Sheila Sprague, Sofia Bzovsky, Taryn Scott, Lehana Thabane, Diane Heels-Ansdell, Robert V O'Toole, Andrea Howe, Greg E. Gaski, Lauren C. Hill, Kri...> ;Injury. 2021 Feb 14
Managing work flow in high enrolling trials: The development and implementation of a sampling strategy in the PREPARE trial.
David Pogorzelski, Uyen Nguyen, Paula McKay, Lehana Thabane, Megan Camara, Lolita Ramsey, Rachel B. Seymour, J. Brett Goodman, Sheketha McGee, Joanne Fraifogl, Andrea ...> ;Contemporary Clinical Trials Communications. 2021 Jan 23
4 citations
Divergence of military and civilian trauma research priorities.
David G. Baer, Ross Donaldson, Todd O. McKinley, Robert E. Guldberg> ;Trauma Surgery & Acute Care Open. 2021 Jun 15
3 citations
Internal Fixation Construct and Defect Size Affect Healing of a Translational Porcine Diaphyseal Tibial Segmental Bone Defect.
Todd O. McKinley, Roman M. Natoli, James P. Fischer, Jeffrey D Rytlewski, David C. Scofield, Rashad H. Usmani, Alexander L Kuzma, Kaitlyn S. Griffin, Emily Jewell, Pau...> ;Military Medicine. 2021 Nov 2
4 citations
Insights into the association between coagulopathy and inflammation: abnormal clot mechanics are a warning of immunologic dysregulation following major injury
Stephanie A. Savage, Ben L. Zarzaur, Greg E. Gaski, Tyler McCarroll, Ruben Zamora, Rami A. Namas, Yoram Vodovotz, Rachael A. Callcut, Timothy R. Billiar, Todd O. McKinley> ;Annals of Translational Medicine. 2020 Nov 24
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Press Mentions

Beating the OddsJune 24th, 2021
Abstracts from the Bone and Muscle Interactions: The Mechanical and Beyond Meeting August 2019May 16th, 2020
Dr. Walter Virkus to Head New Orthopedic Trauma Team at IU Health FeaturedFebruary 12th, 2016