TusharJasubhaiDesaiMDMPH

PubMed

• 1 citations
  Evidence for lung barrier regeneration by differentiation prior to binucleated and stem cell division.
  Joshua Guild, Nicholas H Juul, Andres Andalon, Hiroki Taenaka, Robert J Coffey, Michael A Matthay, Tushar J Desai> ;The Journal of Cell Biology. 2023 Dec 4
• A single-cell atlas of in vitro multiculture systems uncovers the in vivo lineage trajectory and cell state in the human lung.
  Woochan Lee, Seyoon Lee, Jung-Ki Yoon, Dakyung Lee, Yuri Kim, Yeon Bi Han, Rokhyun Kim, Sungji Moon, Young Jun Park, Kyunghyuk Park, Bukyoung Cha, Jaeyong Choi, Juhyun...> ;Experimental & Molecular Medicine. 2023 Aug 1
• 5 citations
  KRAS(G12D) drives lepidic adenocarcinoma through stem-cell reprogramming.
  Nicholas H Juul, Jung-Ki Yoon, Marina C Martinez, Neha Rishi, Yana I Kazadaeva, Maurizio Morri, Norma F Neff, Joseph B Shrager, Rahul Sinha, Tushar J Desai, Trope, W.,...> ;Nature. 2023 Jul 1
• 12 citations
  Alveolar cell fate selection and lifelong maintenance of AT2 cells by FGF signaling.
  Douglas G Brownfield, Alex Diaz de Arce, Elisa Ghelfi, Astrid Gillich, Tushar J Desai, Mark A Krasnow> ;Nature Communications. 2022 Nov 21
• 7 citations
  New Insights into Clinical and Mechanistic Heterogeneity of the Acute Respiratory Distress Syndrome: Summary of the Aspen Lung Conference 2021.
  Thomas R Martin, Rachel L Zemans, Lorraine B Ware, Eric P Schmidt, David W H Riches, Lisa Bastarache, Carolyn S Calfee, Tushar J Desai, Susanne Herold, Catherine L Hou...> ;American Journal of Respiratory Cell and Molecular Biology. 2022 Sep 1
• 6 citations
  Relationship between impaired BMP signalling and clinical risk factors at early-stage vascular injury in the preterm infant.
  Motaharehsadat Heydarian, Prajakta Oak, Xin Zhang, Nona Kamgari, Alida Kindt, Markus Koschlig, Tina Pritzke, Erika Gonzalez-Rodriguez, Kai Förster, Rory E Morty, Fried...> ;Thorax. 2022 Dec 1
• 26 citations
  Dual inhibition of αvβ6 and αvβ1 reduces fibrogenesis in lung tissue explants from patients with IPF.
  Martin Decaris, Johanna R. Schaub, Chun Chen, Cha Jacob, Gail Lee, Megi Rexhepaj, Steve S. Ho, Vikram R. Rao, Megan M. Marlow, Prerna Kotak, Erine H. Budi, Lisa Hooi, ...> ;Respiratory Research. 2021 Oct 19
• 24 citations
  Targeted replacement of full-length CFTR in human airway stem cells by CRISPR-Cas9 for pan-mutation correction in the endogenous locus.
  Sriram Vaidyanathan, Ron Baik, Lu Chen, Dawn T. Bravo, Carlos Suárez, Shayda M. Abazari, Ameen A. Salahudeen, Amanda M. Dudek, Christopher A. Teran, Timothy H. Davis, ...> ;Molecular Therapy. 2021 Mar 29
• 216 citations
  Longitudinal Multi-omics Analyses Identify Responses of Megakaryocytes, Erythroid Cells, and Plasmablasts as Hallmarks of Severe COVID-19.
  Joana P. Bernardes, Neha Mishra, Florian Tran, Thomas Bahmer, Lena Best, Johanna I. Blase, Dora Bordoni, Jeanette Franzenburg, Ulf Geisen, Jonathan Josephs-Spaulding, ...> ;Immunity. 2020 Dec 15
• 218 citations
  Progenitor identification and SARS-CoV-2 infection in human distal lung organoids.
  Ameen A. Salahudeen, Shannon S. Choi, Arjun Rustagi, Junjie Zhu, Vincent van Unen, Sean M. de la O, Ryan A. Flynn, Mar Margalef-Català, António J. M. Santos, Jihang Ju...> ;Nature. 2020 Nov 25
• 4 citations
  Advances in Proximity Ligation in situ Hybridization (PLISH).
  Monica Nagendran, Adam Andruska, Pehr B. Harbury, Tushar J. Desai> ;Bio-Protocol. 2020 Nov 5
• 26 citations
  Progenitor identification and SARS-CoV-2 infection in long-term human distal lung organoid cultures
  Ameen A. Salahudeen, Shannon S. Choi, Arjun Rustagi, Junjie Zhu, Sean M. de la O, Ryan A. Flynn, Mar Margalef-Català, António J. M. Santos, Jihang Ju, Arpit Batish, Vi...> ;Biorxiv. 2020 Jul 27
• 1619 citations
  SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues.
  Kaminski, N., Carly G. K. Ziegler, Samuel J. Allon, Sarah K. Nyquist, Ian M. Mbano, Vincent N. Miao, Constantine N. Tzouanas, Yuming Cao, Ashraf S. Yousif, Julia Bals,...> ;Cell. 2020 May 28
• 2 citations
  Corrigendum: Niche Cells and Signals that Regulate Lung Alveolar Stem Cells In Vivo.
  Nicholas H. Juul, Courtney A. Stockman, Tushar J. Desai> ;Cold Spring Harbor Perspectives in Biology. 2020 May 1
• 17 citations
  Niche Cells and Signals that Regulate Lung Alveolar Stem Cells In Vivo
  Nicholas H. Juul, Courtney A. Stockman, Tushar J. Desai> ;Cold Spring Harbor Perspectives in Biology. 2020 Dec 1
• 77 citations
  High-Efficiency, Selection-free Gene Repair in Airway Stem Cells from Cystic Fibrosis Patients Rescues CFTR Function in Differentiated Epithelia.
  Sriram Vaidyanathan, Ameen A. Salahudeen, Zachary M. Sellers, Dawn T. Bravo, Shannon S. Choi, Arpit Batish, Wei Le, Ron Baik, Sean de la O, Milan Kaushik, Noah Galper,...> ;Cell Stem Cell. 2020 Feb 6
• 58 citations
  Evaluation of integrin αvβ6 cystine knot PET tracers to detect cancer and idiopathic pulmonary fibrosis.
  Richard H. Kimura, Ling Wang, Bin Shen, Li Huo, Willemieke S. Tummers, Fabian V. Filipp, H. Henry Guo, Thomas Haywood, Lotfi Abou-Elkacem, Lucia Baratto, Frezghi Habte...> ;Nature Communications. 2019 Oct 14
• 302 citations
  An atlas of the aging lung mapped by single cell transcriptomics and deep tissue proteomics.
  Ilias Angelidis, Lukas M. Simon, Isis E. Fernandez, Maximilian Strunz, Christoph H. Mayr, Flavia R. Greiffo, George Tsitsiridis, Meshal Ansari, Elisabeth Graf, Tim-Mat...> ;Nature Communications. 2019 Feb 27
• 424 citations
  Single-cell Wnt signaling niches maintain stemness of alveolar type 2 cells
  Ahmad N. Nabhan, Douglas Brownfield, Pehr B. Harbury, Mark A. Krasnow, Tushar J. Desai> ;Science. 2018 Mar 9
• 74 citations
  Automated cell-type classification in intact tissues by single-cell molecular profiling
  Monica Nagendran, Daniel P. Riordan, Pehr B. Harbury, Tushar J. Desai> ;Elife. 2018 Jan 10
• 22 citations
  Attenuated PDGF signaling drives alveolar and microvascular defects in neonatal chronic lung disease.
  Prajakta Oak, Tina Pritzke, Isabella Thiel, Markus Koschlig, Daphne S. Mous, Anita Windhorst, Noopur Jain, Oliver Eickelberg, Kai Foerster, Andreas Schulze, Wolfgang G...> ;EMBO Molecular Medicine. 2017 Nov 1
• 22 citations
  Early Identification of Bronchopulmonary Dysplasia Using Novel Biomarkers by Proteomic Screening
  Kai Förster, Steffen Sass, Harald Ehrhardt, Daphne S. Mous, Robbert J. Rottier, Prajakta Oak, Andreas Schulze, Andreas W. Flemmer, Judith Gronbach, Christoph Hübener, ...> ;American Journal of Respiratory and Critical Care Medicine. 2017 Oct 20
• 6 citations
  Trinucleotide repeat containing 6c (TNRC6c) is essential for microvascular maturation during distal airspace sacculation in the developing lung
  Hua Guo, Yana Kazadaeva, Fabian E. Ortega, Narasimaswamy Manjunath, Tushar J. Desai> ;Developmental Biology. 2017 Oct 1
• 2 citations
  Hedgehog-driven myogenic tumors recapitulate skeletal muscle cellular heterogeneity
  Simone Hettmer, Michael M. Lin, Daria Tchessalova, Sara J. Tortorici, Alessandra Castiglioni, Tushar J. Desai, Junhao Mao, Andrew P. McMahon, Amy J. Wagers> ;Experimental Cell Research. 2016 Jan 1
• 21 citations
  Keeping it together: Pulmonary alveoli are maintained by a hierarchy of cellular programs.
  Catriona Y. Logan, Tushar J. Desai> ;Bioessays. 2015 Sep 1
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