UlusAtasoyMD

Allergy & Immunology • Ann Arbor, MI

Associate Professor, Surgery, University of Missouri, Columbia School of Medicine

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Office
24 Frank Lloyd Wright Dr
Ste H-2100
Ann Arbor, MI 48105
Phone+1 573-882-6921

Fax+1 573-884-1154
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Education & Training

Duke University HospitalFellowship, Allergy and Immunology, 1990 - 1993
National Institutes of Health Clinical CenterFellowship, Allergy and Immunology, 1987 - 1990
UCLA David Geffen School of Medicine/UCLA Medical CenterResidency, Pediatrics, 1984 - 1987
University of Minnesota Medical SchoolClass of 1984

Certifications & Licensure

CA State Medical License 1985 - Present
MI State Medical License 2017 - 2024
MO State Medical License 2005 - 2018
NC State Medical License 1990 - 2006
MD State Medical License 1987 - 1990
American Board of Allergy and Immunology Allergy & Immunology

Publications & Presentations

PubMed

4 citations
HuR-Targeted Inhibition Impairs Th2 Proinflammatory Responses in Asthmatic CD4+ T Cells.
Fatemeh Fattahi, Jason Ellis, Michael J. Sylvester, Kristin Bahleda, Samuel Hietanen, Luis Correa, Njira L Lugogo, Ulus Atasoy> ;Journal of Immunology. 2021 Dec 3
15 citations
Mechanistic dissection of dominant AIRE mutations in mouse models reveals AIRE autoregulation.
Yael Goldfarb, Tal Givony, Noam Kadouri, Jan Dobeš, Cristina Peligero-Cruz, Itay Zalayat, Golda M. Damari, Bareket Dassa, Shifra Ben-Dor, Yael Gruper, Bergithe E. Ofte...> ;The Journal of Experimental Medicine. 2021 Nov 1
6 citations
HuR Plays a Positive Role to Strengthen the Signaling Pathways of CD4+ T Cell Activation and Th17 Cell Differentiation
Shiguang Yu, Morgan Tripod, Ulus Atasoy, Jing Chen> ;Journal of Immunology Research. 2021 Aug 4
45 citations
IL-17 integrates multiple self-reinforcing, feed-forward mechanisms through the RNA binding protein Arid5a
Nilesh Amatya, Erin E. Childs, J. Agustin Cruz, Felix E. Y. Aggor, Abhishek V. Garg, Andrea J. Berman, Johann E. Gudjonsson, Ulus Atasoy, Sarah L. Gaffen> ;Science Signaling. 2018 Oct 9
18 citations
Interaction of RNA-binding protein HuR and miR-466i regulates GM-CSF expression.
Jing Chen, William Adamiak, Ganlei Huang, Ulus Atasoy, Abdolmohamad Rostami, Shiguang Yu> ;Scientific Reports. 2017 Dec 8
17 citations
The RNA-Binding Protein HuR Posttranscriptionally Regulates IL-2 Homeostasis and CD4+ Th2 Differentiation.
Patsharaporn Techasintana, Jason S. Ellis, Jacqueline J. Glascock, Matthew M. Gubin, Suzanne E. Ridenhour, Joseph D. Magee, Marcia L. Hart, Peng Yao, Hao Zhou, Maryln ...> ;Immunohorizons. 2017 Aug 1
24 citations
The RNA-binding protein HuR contributes to neuroinflammation by promoting C-C chemokine receptor 6 (CCR6) expression on Th17 cells
Jing Chen, Jennifer L. Martindale, Carole L. Cramer, Myriam Gorospe, Ulus Atasoy, Paul D. Drew, Shiguang Yu> ;The Journal of Biological Chemistry. 2017 Sep 1
11 citations
Transcriptomic-Wide Discovery of Direct and Indirect HuR RNA Targets in Activated CD4+ T Cells.
Patsharaporn Techasintana, J. Wade Davis, Matthew M. Gubin, Joseph D. Magee, Ulus Atasoy> ;Plos One. 2015 Jul 10
41 citations
Identification of a human papillomavirus-associated oncogenic miRNA panel in human oropharyngeal squamous cell carcinoma validated by bioinformatics analysis of the Ca...
Daniel L. Miller, J. Wade Davis, Kristen H. Taylor, Jeffrey J. Johnson, Zonggao Shi, Russell Williams, Ulus Atasoy, James S. Lewis, M. Sharon Stack> ;The American Journal of Pathology. 2015 Mar 1
29 citations
Conditional Knockout of the RNA-Binding Protein HuR in CD4 + T Cells Reveals a Gene Dosage Effect on Cytokine Production
Matthew M. Gubin, Patsharaporn Techasintana, Joseph D. Magee, Garrett M. Dahm, Robert Calaluce, Jennifer L. Martindale, Maryln S. Whitney, Craig L. Franklin, Cindy Bes...> ;Molecular Medicine. 2014 Mar 20
64 citations
Posttranscriptional Gene Regulation of IL-17 by the RNA-Binding Protein HuR Is Required for Initiation of Experimental Autoimmune Encephalomyelitis
Jing Chen, Jason A. Cascio, Joseph D. Magee, Patsharaporn Techasintana, Matthew M. Gubin, Garrett M. Dahm, Robert Calaluce, Shiguang Yu, Ulus Atasoy> ;Journal of Immunology. 2013 Dec 1
19 citations
Incisional hernia recurrence through genomic profiling: a pilot study
Robert Calaluce, Justin Wade Davis, Sharon L. Bachman, Matthew M. Gubin, J. A. Brown, Joseph D. Magee, T. S. Loy, Bruce Ramshaw, Ulus Atasoy> ;Hernia. 2013 Apr 1
15 citations
Method for the isolation and identification of mRNAs, microRNAs and protein components of ribonucleoprotein complexes from cell extracts using RIP-Chip.
Garrett M. Dahm, Matthew M. Gubin, Joseph D. Magee, Patsharaporn Techasintana, Robert Calaluce, Ulus Atasoy> ;Journal of Visualized Experiments. 2012 Sep 29
39 citations
Coordinate Regulation of GATA-3 and Th2 Cytokine Gene Expression by the RNA-Binding Protein HuR
Cristiana Stellato, Matthew M. Gubin, Joseph D. Magee, Xi Fang, Jinshui Fan, Danielle M. Tartar, Jing Chen, Garrett M. Dahm, Robert Calaluce, Francesca Mori, Glenn A. ...> ;Journal of Immunology. 2011 Jul 1
69 citations
Chemokine transcripts as targets of the RNA-binding protein HuR in human airway epithelium.
Jinshui Fan, Faoud T. Ishmael, Xi Fang, Allen C. Myers, Chris Cheadle, Shau Ku Huang, Ulus Atasoy, Myriam Gorospe, Cristiana Stellato> ;Journal of Immunology. 2011 Feb 15
51 citations
Overexpression of the RNA binding protein HuR impairs tumor growth in triple negative breast cancer associated with deficient angiogenesis.
Matthew M. Gubin, Robert Calaluce, Justin Wade Davis, Joseph D. Magee, Connie S. Strouse, Daniel P. Shaw, Lixin Ma, Ashley Brown, Timothy J. Hoffman, Tammy L. Rold, Ul...> ;Cell Cycle. 2010 Aug 15
49 citations
The RNA binding protein HuR differentially regulates unique subsets of mRNAs in estrogen receptor negative and estrogen receptor positive breast cancer
Robert Calaluce, Matthew M. Gubin, J. Wade Davis, Joseph D. Magee, Jing Chen, Yuki Kuwano, Myriam Gorospe, Ulus Atasoy> ;BMC Cancer. 2010 Apr 6
274 citations
Circulating microRNAs in breast cancer and healthy subjects.
Weizhu Zhu, Wenyi Qin, Ulus Atasoy, Edward R. Sauter> ;BMC Research Notes. 2009 May 19
76 citations
Role of the RNA-Binding Protein Tristetraprolin in Glucocorticoid-Mediated Gene Regulation
Faoud T. Ishmael, Xi Fang, Maria Rosaria Galdiero, Ulus Atasoy, William F. C. Rigby, Myriam Gorospe, Chris Cheadle, Cristiana Stellato> ;Journal of Immunology. 2008 Jun 15
59 citations
Posttranscriptional regulation of IL-13 in T cells: role of the RNA-binding protein HuR.
Vincenzo Casolaro, Xi Fang, B. Tancowny, Jinshui Fan, Fan Wu, Subramanya Srikantan, S. Yukiko Asaki, Umberto De Fanis, Shau Ku Huang, Myriam Gorospe, Ulus Atasoy, Cris...> ;The Journal of Allergy and Clinical Immunology. 2008 Apr 1
17 citations
Increased expression of the inflammatory protein YKL-40 in precancers of the breast
Wenyi Qin, Weizhu Zhu, Lisa Schlatter, Ronald Miick, Timothy S. Loy, Ulus Atasoy, John E. Hewett, Edward R. Sauter> ;International Journal of Cancer. 2007 Oct 1
25 citations
The regulation of glucose transporter (GLUT1) expression by the RNA binding protein HuR
Kira R. Gantt, Joy Cherry, Melissa Richardson, Vesna A. Karschner, Ulus Atasoy, Phillip H. Pekala> ;Journal of Cellular Biochemistry. 2006 Oct 1
84 citations
The role of post-transcriptional regulation in chemokine gene expression in inflammation and allergy
Jinshui Fan, Nicola M. Heller, Myriam Gorospe, Ulus Atasoy, Cristiana Stellato> ;The European Respiratory Journal. 2005 Nov 1
26 citations
Genome-wide regulatory analysis using en masse nuclear run-ons emRUNs and ribonomic profiling with autoimmune sera
Scott A. Tenenbaum, Craig C. Carson, Ulus Atasoy, Jack D. Keene> ;Gene. 2003 Oct 23
105 citations
Regulation of Eotaxin Gene Expression by TNF-α and IL-4 Through mRNA Stabilization: Involvement of the RNA-Binding Protein HuR
Ulus Atasoy, Stephanie L. Curry, Isabel López de Silanes, Ann-Bin Shyu, Vincenzo Casolaro, Myriam Gorospe, Cristiana Stellato> ;Journal of Immunology. 2003 Oct 15
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Grant Support

Hur In Allergic AsthmaNational Institute Of Allergy And Infectious Diseases2009–2011
Posttranscriptional Gene Regulation In AsthmaNational Institute Of Allergy And Infectious Diseases2009–2010
ADA And Premature Termination CodonsNational Institute Of Allergy And Infectious Diseases1994–1996
NIH Intramural Nrsa Institutional Training ProgramNational Institute Of Allergy And Infectious Diseases1987–1989

Hospital Affiliations

University of Michigan Medical CenterAnn Arbor, Michigan