WadeLarryThorstadMD

Radiation Oncology • Saint Louis, MO

Associate Professor, Radiation Oncology, Washington University in St. Louis School of Medicine

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Office
4921 Parkview Pl
Siteman Cancer Center Lower Level
Saint Louis, MO 63110
Phone+1 314-747-7236

Fax+1 314-362-7769
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Education & Training

Duke University HospitalResidency, Nuclear Medicine, 1995 - 1997
Loyola University Medical CenterResidency, Radiation Oncology, 1992 - 1995
University of Arkansas for Medical Sciences (UAMS) College of MedicineInternship, Transitional Year, 1991 - 1992
McGovern Medical School at UTHealthClass of 1991

Certifications & Licensure

IL State Medical License 1992 - 2026
MO State Medical License 2000 - 2025
FL State Medical License 1997 - 2000
TX State Medical License 1992 - 2000
NC State Medical License 1995 - 1997
American Board of Radiology Radiation Oncology

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification MOSAIQ EMR, Elekta, 2012

Clinical Trials

Study of Amifostine and IMRT for Protecting Salivary Glands in Head and Neck Cancer Start of enrollment: 2001 Oct 01
Completed
Phase 2
Phase II Trial Evaluating Elimination of Radiation Therapy Start of enrollment: 2007 Apr 11
Active, not recruiting
Phase 2
A Feasibility Study of Adaptive Intensity-Modulated Radiation Therapy Start of enrollment: 2007 Jan 01
Terminated
Early Phase 1
Radiation Therapy With or Without Cetuximab in Treating Patients Who Have Undergone Surgery for Locally Advanced Head and Neck Cancer Start of enrollment: 2009 Nov 01
Active, not recruiting
Phase 3
Post Operative Adjuvant Therapy De-intensification Trial for Human Papillomavirus-related, p16+ Oropharynx Cancer Start of enrollment: 2013 Jan 10
Terminated
Phase 3
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Publications & Presentations

PubMed

Trends in ototoxicity monitoring among cisplatin-treated patients with cancer.
David S Lee, Emma Y Travis, Susan K Wong, Marie-Ange Munyemana, Lauren Mueller, Cathryn Collopy Rowling, Jason T Rich, Patrik Pipkorn, Sidharth V Puram, Ryan S Jackson...> ;Journal of Cancer Survivorship. 2024 Apr 17
1 citations
Poor Dental Health as a Risk Factor for Alveolar Ridge Malignancies.
Katherine W Chang, Angela L Mazul, Daniel P Lander, Benjamin M Wahle, Emily Z Yan, Wade L Thorstad, Sidharth V Puram, Ryan S Jackson, Patrik Pipkorn, Randal C Paniello...> ;Otolaryngology--Head and Neck Surgery. 2024 Apr 1
Immune Cell Deconvolution Reveals Possible Association of γδ T Cells with Poor Survival in Head and Neck Squamous Cell Carcinoma.
Anuraag S Parikh, Yize Li, Angela Mazul, Victoria X Yu, Wade Thorstad, Jason Rich, Randal C Paniello, Salvatore M Caruana, Scott H Troob, Ryan S Jackson, Paul Zolkind,...> ;Cancers. 2023 Oct 5
11 citations
Cellular states are coupled to genomic and viral heterogeneity in HPV-related oropharyngeal carcinoma.
Sidharth V Puram, Michael Mints, Ananya Pal, Zongtai Qi, Ashley Reeb, Kyla Gelev, Thomas F Barrett, Sophie Gerndt, Ping Liu, Anuraag S Parikh, Salma Ramadan, Travis La...> ;Nature Genetics. 2023 Apr 1
1 citations
F-FDG PET/CT Prediction of Treatment Outcomes in Human Papillomavirus-Positive, Locally Advanced Oropharyngeal Cancer Patients Receiving Deintensified Therapy: Results...
Rathan M Subramaniam, Lyudmila DeMora, Min Yao, Sue S Yom, Maura Gillison, Jimmy J Caudell, John Waldron, Ping Xia, Christine H Chung, Minh Tam Truong, Michelle Echeva...> ;Journal of Nuclear Medicine. 2023 Mar 1
Hearing Outcomes in a Deintensification Trial of Adjuvant Therapy for HPV-Related Oropharyngeal Squamous Cell Carcinoma.
David S Lee, Rajwant S Mahal, Theresa Tharakan, Cathryn Collopy, Dorina Kallogjeri, Wade L Thorstad, Douglas R Adkins, Peter Oppelt, Jessica Ley, Cameron C Wick, Jose ...> ;Otolaryngology--Head and Neck Surgery. 2023 May 1
No survival benefit in never-smoker never-drinker patients with oral cavity cancer.
Emily Z Yan, Benjamin M Wahle, Smrithi Chidambaram, Kayla Getz, Wade L Thorstad, Jose P Zevallos, Angela L Mazul, Nakken, E.> ;Head & Neck. 2023 Mar 1
8 citations
Image analysis reveals differences in tumor multinucleations in Black and White patients with human papillomavirus-associated oropharyngeal squamous cell carcinoma.
Can F Koyuncu, Reetoja Nag, Cheng Lu, Germán Corredor, Vidya S Viswanathan, Vlad C Sandulache, Pingfu Fu, Kailin Yang, Quintin Pan, Zelin Zhang, Jun Xu, Deborah J Chut...> ;Cancer. 2022 Nov 1
6 citations
Combining natural and artificial intelligence for robust automatic anatomy segmentation: Application in neck and thorax auto-contouring.
Jayaram K Udupa, Tiange Liu, Chao Jin, Liming Zhao, Dewey Odhner, Yubing Tong, Vibhu Agrawal, Gargi Pednekar, Sanghita Nag, Tarun Kotia, Michael Goodman, E Paul Wileyt...> ;Medical Physics. 2022 Nov 1
1 citations
Risk Factors for Functional Outcomes in Advanced Laryngeal Squamous Cell Carcinoma.
David S Lee, Jake J Lee, Parul Sinha, Sidharth V Puram, Ryan S Jackson, Douglas R Adkins, Peter Oppelt, Randall Brenneman, Wade L Thorstad, Pipkorn, P.> ;The Laryngoscope. 2023 Mar 1
7 citations
Integrative genomic analysis reveals low T-cell infiltration as the primary feature of tobacco use in HPV-positive oropharyngeal cancer.
Benjamin M Wahle, Paul Zolkind, Ricardo J Ramirez, Zachary L Skidmore, Sydney R Anderson, Angela Mazul, D Neil Hayes, Vlad C Sandulache, Wade L Thorstad, Douglas Adkin...> ;Iscience. 2022 May 20
3 citations
Development of second primary malignancies after transoral surgery in human papilloma virus-positive oropharyngeal squamous cell carcinoma.
Katelyn Stepan, Ethan Craig, Scott Andrew Skillington, Brian C Deutsch, Stephanie Chen, Nneoma S Wamkpah, Craig A Bollig, Dorina Kallogjeri, Wade L Thorstad, Sidharth ...> ;Head & Neck. 2022 May 1
Osteonectin/SPARC Expression in Head and Neck Squamous Cell Carcinoma: A Tissue Microarray Study.
James S Lewis Jr, Wade L Thorstad, Mohammad Hussaini> ;Applied Immunohistochemistry & Molecular Morphology. 2022 Mar 29
1 citations
Learning-based Cancer Treatment Outcome Prognosis using Multimodal Biomarkers.
Maliazurina Saad, Shenghua He, Wade Thorstad, Hiram Gay, Daniel Barnett, Yujie Zhao, Su Ruan, Xiaowei Wang, Hua Li> ;IEEE Transactions on Radiation and Plasma Medical Sciences. 2022 Feb 1
8 citations
An Imaging Biomarker of Tumor-Infiltrating Lymphocytes to Risk-Stratify Patients with HPV-Associated Oropharyngeal Cancer.
Germán Corredor, Paula Toro, Can Fahrettin Koyuncu, Cheng Lu, Christina Buzzy, Kaustav Bera, Pingfu Fu, Mitra Mehrad, Kim Ely, Mojgan Mokhtari, Kailin Yang, Deborah J....> ;Journal of the National Cancer Institute. 2021 Nov 29
A Rational Approach to Unilateral Neck RT for Head and Neck Cancers in the Era of Immunotherapy.
R.I. Chin, J.P. Schiff, Randall Brenneman, Wade L. Thorstad, Alexander J. Lin> ;Cancers. 2021 Oct 20
5 citations
Impact of human papillomavirus on the tumor microenvironment in oropharyngeal squamous cell carcinoma.
Xinyi Liu, Ping Liu, Rebecca D. Chernock, Krystle A. Lang Kuhs, James S. Lewis, Hua Li, Wade L. Thorstad, Xiaowei Wang> ;International Journal of Cancer. 2021 Oct 16
In Regard to Amdur et al.
Muhammad Shahid Iqbal, James O'Hara, Wade L. Thorstad, Josef Kovarik, Rahul Patil, Charles Kelly> ;Practical Radiation Oncology. 2021 May 1
A novel systematic approach for cancer treatment prognosis and its applications in oropharyngeal cancer with microRNA biomarkers.
Shenghua He, Chunfeng Lian, Wade L. Thorstad, Yujie Zhao, Su Ruan, Xiaowei Wang, Hua Li> ;Bioinformatics. 2021 Oct 11
5 citations
The impact of age on outcome in phase III NRG Oncology/RTOG trials of radiotherapy (XRT) +/- systemic therapy in locally advanced head and neck cancer.
Julie A. Kish, Qiang Zhang, Corey J. Langer, Phuc Felix Nguyen-Tân, David I. Rosenthal, Randal S. Weber, Marcy A. List, Stuart J. Wong, Adam S. Garden, Kenneth S. Hu, ...> ;Journal of Geriatric Oncology. 2021 Apr 2
15 citations
Association Between Surgical Margins Larger Than 1 cm and Overall Survival in Patients With Merkel Cell Carcinoma.
Neal Andruska, Benjamin W. Fischer-Valuck, Lily Mahapatra, Randall Brenneman, Wade L. Thorstad, Ryan C. Fields, Kelly M. MacArthur, Brian C. Baumann> ;JAMA Dermatology. 2021 Mar 24
11 citations
nab-Paclitaxel and cisplatin followed by cisplatin and radiation (Arm 1) and nab-paclitaxel followed by cetuximab and radiation (Arm 2) for locally advanced head and n...
Peter Oppelt, Jessica Ley, Mackenzie Daly, Jason T. Rich, Randal C. Paniello, Ryan S. Jackson, Jingxia Liu, Kevin Palka, Prakash Neupane, Steven Francis Powell, Willia...> ;Medical Oncology. 2021 Mar 8
14 citations
Computerized tumor multinucleation index (MuNI) is prognostic in p16+ oropharyngeal carcinoma
Can Fahrettin Koyuncu, Cheng Lu, Kaustav Bera, Zelin Zhang, Jun Xu, Paula Toro, Germán Corredor, Deborah J. Chute, Pingfu Fu, Wade L. Thorstad, Farhoud Faraji, Justin ...> ;The Journal of Clinical Investigation. 2021 Apr 26
4 citations
Risk groups of laryngeal cancer treated with chemoradiation according to nomogram scores - A pooled analysis of RTOG 0129 and 0522.
Musaddiq J. Awan, Haley Gittleman, Jill S. Barnholtz-Sloan, Mitchell Machtay, Phuc Felix Nguyen-Tan, David I. Rosenthal, Christopher J. Schultz, Bradley Joseph Huth, W...> ;Oral Oncology. 2021 May 1
21 citations
Oropharyngeal Squamous Cell Carcinoma With Discordant p16 and HPV mRNA Results: Incidence and Characterization in a Large, Contemporary United States Cohort.
Justin R. Shinn, Seth J. Davis, Krystle A. Lang-Kuhs, Sarah L. Rohde, Xiaowei Wang, Ping Liu, William D. Dupont, Dale Plummer, Wade L. Thorstad, Rebecca D. Chernock, M...> ;The American Journal of Surgical Pathology. 2021 Feb 22
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Journal Articles

Predictors of Acute Throat or Esophageal Patient Reported Pain During Radiation Therapy for Head and Neck Cancer
Hiram A Gay, Bruce H Haughey, Wade L Thorstad, Douglas R Adkins, Pawel T Dyk, Brian Nussenbaum, Mackenzie D Daly, Jason Rich, Clinical and Translational Radiation Oncology

Press Mentions

WashU ENT Has Strong Presence at Annual AAO-HNSF MeetingAugust 30th, 2022
Palliative Expeditiously Adaptive Quad Shot Radiation Therapy (PEAQ-RT) (PEAQ-RT)May 7th, 2020
Long-Term Results of the Omission of Postoperative Radiation to the Pathologically Node-Negative Neck in Primary HNSCCJuly 9th, 2019
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