WayneLFurmanMD

Pediatric Hematology & Oncology • Memphis, TN

Professor of Pediatrics, University Tenn College of Medicine

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Office
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105
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Summary

Dr. Wayne Furman is a pediatric hematologist/oncologist in Memphis, TN and is affiliated with multiple hospitals in the area, including St. Jude Children's Research Hospital and Methodist Healthcare Memphis Hospitals. He received his medical degree from Ohio State University College of Medicine and has been in practice 38 years. He is experienced in neuroblastoma, hepatoblastoma, pediatric sarcomas, hepatocellular cancer, and drug development.

Education & Training

University of TennesseeFellowship, Pediatric Hematology/Oncology, 1983 - 1985
Nationwide Children's Hospital/Ohio State UniversityResidency, Pediatrics, 1979 - 1983
Ohio State University College of MedicineClass of 1979

Certifications & Licensure

TN State Medical License 1983 - 2024
OH State Medical License 1982 - 1984
American Board of Pediatrics Pediatrics
American Board of Pediatrics Pediatric Hematology-Oncology

Awards, Honors, & Recognition

America's Top Doctors Castle Connolly, 2009-2014
Memphis Magazine: Top Doctors Castle Connolly, 2010, 2014
America's Top Doctors for Cancer Castle Connolly, 2006-2013

Clinical Trials

Topotecan in Treating Children With Refractory Leukemia Start of enrollment: 1996 Apr 01
Completed
Phase 1
Irinotecan Followed By Fluorouracil and Leucovorin in Treating Patients With Stage III or Stage IV Colorectal Carcinoma (Cancer), Other Refractory Carcinoma, or Metastatic Adenoma (Cancer) of Unknown Primary Origin Start of enrollment: 1998 Sep 01
Completed
Phase 2
Isotretinoin With or Without Dinutuximab, Aldesleukin, and Sargramostim Following Stem Cell Transplant in Treating Patients With Neuroblastoma Start of enrollment: 2001 Oct 18
Active, not recruiting
Phase 3
Genetic Analysis in Identifying Late-Occurring Complications in Childhood Cancer Survivors Start of enrollment: 2004 Mar 25
Recruiting
Therapy for Children With Neuroblastoma Start of enrollment: 2005 Aug 01
Completed
Phase 2
Therapy for Children With Advanced Stage High Risk Neuroblastoma Start of enrollment: 1997 Oct 01
Completed
Phase 2
Study of ZD1839 Combined With Irinotecan and Vincristine in Pediatric Patients With Refractory Solid Tumors Start of enrollment: 2003 May 01
Completed
Phase 1
Everolimus for Treating Pediatric Patients With Recurrent or Refractory Tumors Start of enrollment: 2004 Oct 01
Completed
Phase 1
Combination Chemotherapy, Autologous Stem Cell Transplant, and/or Radiation Therapy in Treating Young Patients With Extraocular Retinoblastoma Start of enrollment: 2008 Feb 04
Active, not recruiting
Phase 3
Long-Term Follow-Up of Patients Who Have Participated in Children's Oncology Group Studies Start of enrollment: 2008 Jul 17
Recruiting
Neuropsychological and Behavioral Testing in Younger Patients With Cancer Start of enrollment: 2009 Feb 27
Recruiting
Neuroblastoma Protocol 2008: Therapy for Children With Advanced Stage High Risk Neuroblastoma Start of enrollment: 2008 Dec 01
Terminated
Phase 2
Study of Kidney Tumors in Younger Patients Start of enrollment: 2006 Feb 27
Recruiting
Biomarkers in Tumor Tissue Samples From Patients With Newly Diagnosed Neuroblastoma or Ganglioneuroblastoma Start of enrollment: 2000 Nov 06
Recruiting
Combination Chemotherapy and Surgery in Treating Young Patients With Wilms Tumor Start of enrollment: 2009 Jul 13
Active, not recruiting
Phase 3
Risk-Based Therapy in Treating Younger Patients With Newly Diagnosed Liver Cancer Start of enrollment: 2009 Sep 14
Active, not recruiting
Phase 3
Maintenance Chemotherapy or Observation Following Induction Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Ependymoma Start of enrollment: 2010 May 07
Active, not recruiting
Phase 3
Combination Chemotherapy in Treating Patients With Non-Metastatic Extracranial Ewing Sarcoma Start of enrollment: 2010 Nov 22
Active, not recruiting
Phase 3
Combination Chemotherapy, Monoclonal Antibody, and Natural Killer Cells in Treating Young Patients With Recurrent or Refractory Neuroblastoma Start of enrollment: 2012 Apr 01
Completed
Phase 1
Chemotherapy Followed by Radiation Therapy in Treating Younger Patients With Newly Diagnosed Localized Central Nervous System Germ Cell Tumors Start of enrollment: 2012 Jun 27
Active, not recruiting
Phase 2
Cabozantinib S-Malate in Treating Younger Patients With Recurrent or Refractory Solid Tumors Start of enrollment: 2012 Nov 14
Completed
Phase 1
MORAb-004 in Treating Young Patients With Recurrent or Refractory Solid Tumors or Lymphoma Start of enrollment: 2013 Nov 01
Completed
Phase 1
Brentuximab Vedotin and Gemcitabine Hydrochloride in Treating Younger Patients With Relapsed or Refractory Hodgkin Lymphoma Start of enrollment: 2013 Jan 31
Completed
Phase 1, Phase 2
Blood Sample Markers of Reproductive Hormones in Assessing Ovarian Reserve in Younger Patients With Newly Diagnosed Lymphomas Start of enrollment: 2013 Jun 17
Active, not recruiting
Therapy for Children With Advanced Stage Neuroblastoma Start of enrollment: 2013 Jul 05
Active, not recruiting
Phase 2
Adavosertib and Local Radiation Therapy in Treating Children With Newly Diagnosed Diffuse Intrinsic Pontine Gliomas Start of enrollment: 2013 Sep 03
Completed
Phase 1
Talazoparib and Temozolomide in Treating Younger Patients With Refractory or Recurrent Malignancies Start of enrollment: 2014 May 16
Completed
Phase 1, Phase 2
VEGF Receptor Tyrosine Kinase Inhibitor Axitinib in Children With Recurrent or Refractory Solid Tumors Start of enrollment: 2014 Sep 01
Completed
Phase 1
Risk-Based Therapy in Treating Younger Patients With Newly Diagnosed Liver Cancer Start of enrollment: 2009 Sep 01
A Study of Ramucirumab (LY3009806) in Children With Refractory Solid Tumors Start of enrollment: 2015 Dec 11
Completed
Phase 1
Irinotecan Hydrochloride, Temozolomide, and Dinutuximab With or Without Eflornithine in Treating Patients With Relapsed or Refractory Neuroblastoma Start of enrollment: 2019 Jul 08
Active, not recruiting
Phase 2
Pilot Study to Enable Electronic Laboratory Data Transfer From Participating Institutions to MediData/RAVE Start of enrollment: 2021 Aug 28
Active, not recruiting
Roles: Principal Investigator, Contact
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Publications & Presentations

PubMed

2 citations
Aggressive Pursuit of No Evidence of Disease Status in Hepatoblastoma Improves Survival: An Observational Study.
Andrew M Fleming, Andrew J Murphy, Suraj Sarvode Mothi, Rodrigo B Interiano, Amos Loh, Mary E McCarville, Zachary Abramson, Sara A Mansfield, Hafeez Abdelhafeez, Andre...> ;Journal of Pediatric Surgery. 2023 Jun 1
A retrospective investigation of the relationship between neuroblastoma response to anti-GD2 monoclonal antibodies and exposure to opioids for pain management.
Kyle J Morgan, Andrew Dudas, Wayne L Furman, M Beth McCarville, Barry L Shulkin, Zhaohua Lu, Himani Darji, Doralina L Anghelescu> ;Pediatric Blood & Cancer. 2023 Feb 1
5 citations
Outcomes of children with well-differentiated fetal hepatoblastoma treated with surgery only: Report from Children's Oncology Group Trial, AHEP0731.
Sanjeev A Vasudevan, Rebecka L Meyers, Milton J Finegold, Dolores López-Terrada, Sarangarajan Ranganathan, Stephen P Dunn, Max R Langham, Eugene D McGahren, Greg M Tia...> ;Journal of Pediatric Surgery. 2022 Oct 1
Risk factors associated with metastatic site failure in patients with high-risk neuroblastoma.
John Thomas Lucas Jr, Daniel Victor Wakefield, Michael Doubrovin, Yimei Li, Teresa Santiago, Sara Michele Federico, Thomas E Merchant, Andrew M Davidoff, Matthew J Kra...> ;Clinical and Translational Radiation Oncology. 2022 May 1
10 citations
Small Cell Undifferentiated Histology Does Not Adversely Affect Outcome in Hepatoblastoma: A Report From the Children's Oncology Group (COG) AHEP0731 Study Committee.
Angela Trobaugh-Lotrario, Howard M Katzenstein, Sarangarajan Ranganathan, Dolores Lopez-Terrada, Mark D Krailo, Jin Piao, Nadia Chung, Jessica Randazzo, Marcio H Malog...> ;Journal of Clinical Oncology. 2022 Feb 10
37 citations
Improved Outcome in Children With Newly Diagnosed High-Risk Neuroblastoma Treated With Chemoimmunotherapy: Updated Results of a Phase II Study Using hu14.18K322A.
Wayne L Furman, Beth McCarville, Barry L Shulkin, Andrew Davidoff, Matthew Krasin, Chia-Wei Hsu, Haitao Pan, Jianrong Wu, Rachel Brennan, Michael W Bishop, Sara Helmig...> ;Journal of Clinical Oncology. 2022 Feb 1
12 citations
Doxorubicin in combination with cisplatin, 5-flourouracil, and vincristine is feasible and effective in unresectable hepatoblastoma: A Children's Oncology Group study
Howard M. Katzenstein, Marcio H. Malogolowkin, Mark Krailo, Jin Piao, Alexander J. Towbin, M. Beth McCarville, Gregory M. Tiao, Stephen P. Dunn, Max R. Langham, Eugene...> ;Cancer. 2021 Nov 11
3 citations
Interstitial lung disease in children with Rubinstein-Taybi syndrome.
Lauren Bradford, Mindy K. Ross, Jagila Minso, Mateja Cernelc-Kohan, Katayoon Shayan, Simon S. Wong, Xiaoping Li, Lauraine H. Rivier, Anil G. Jegga, Gail H. Deutsch, Ti...> ;Pediatric Pulmonology. 2021 Sep 29
ASO Visual Abstract: Impact of Neoadjuvant Chemotherapy on Image-Defined Risk Factors in High-Risk Neuroblastoma.
Sara A. Mansfield, M. Beth McCarville, John T. Lucas, Matthew J. Krasin, Sara M. Federico, Victor M. Santana, Wayne L. Furman, Andrew M. Davidoff> ;Annals of Surgical Oncology. 2021 Sep 13
10 citations
Impact of Neoadjuvant Chemotherapy on Image-Defined Risk Factors in High-Risk Neuroblastoma.
Sara A. Mansfield, M. Beth McCarville, John T. Lucas, Matthew J. Krasin, Sara M. Federico, Victor M. Santana, Wayne L. Furman, Andrew M. Davidoff> ;Annals of Surgical Oncology. 2021 Jul 2
11 citations
Monoclonal Antibody Therapies for High Risk Neuroblastoma.
Wayne L. Furman> ;Biologics. 2021 Jun 9
2 citations
Pharmacokinetically guided dosing of oral sorafenib in pediatric hepatocellular carcinoma: A simulation study.
John C. Panetta, Olivia Campagne, Jessica Gartrell, Wayne L. Furman, Clinton F. Stewart> ;Clinical and Translational Science. 2021 Jun 1
Bilateral Diffuse Nodular Pulmonary Ossification Mimicking Metastatic Disease in a Patient with Fibrolamellar Hepatocellular Carcinoma.
Pattamon Sutthatarn, Cara E. Morin, Jessica Gartrell, Wayne L. Furman, Max R Langham, Teresa Santiago, Andrew J. Murphy> ;Children. 2021 Mar 16
6 citations
Induction Chemotherapy With an Anti-GD2 Monoclonal Antibody (Dinutuximab) and Cytokines in Children With Newly Diagnosed High-risk Neuroblastoma: A Case Series.
Jessica Gartrell, Barry L. Shulkin, Sara Helmig, Kenneth J. Caldwell, Wayne L. Furman, Sara M. Federico> ;Journal of Pediatric Hematology/oncology. 2021 Jul 1
14 citations
Next-generation humanized patient-derived xenograft mouse model for pre-clinical antibody studies in neuroblastoma
Rosa Nguyen, Anand G. Patel, Lyra Griffiths, Jason Dapper, Elizabeth Stewart, Jim Houston, Melissa Johnson, Walter J. Akers, Wayne L. Furman, Michael A. Dyer> ;Cancer Immunology, Immunotherapy. 2021 Mar 1
34 citations
A phase I trial of talazoparib and irinotecan with and without temozolomide in children and young adults with recurrent or refractory solid malignancies
Sara M. Federico, Alberto S. Pappo, Natasha Sahr, April Sykes, Olivia Campagne, Clinton F. Stewart, Michael R. Clay, Armita Bahrami, Mary Beth McCarville, Sue C. Kaste...> ;European Journal of Cancer. 2020 Sep 1
4 citations
A Phase 1 and pharmacokinetic study evaluating daily or weekly schedules of the humanized anti-GD2 antibody hu14.18K322A in recurrent/refractory solid tumors.
Michael W. Bishop, Paul R. Hutson, Jacquelyn A. Hank, Paul M. Sondel, Wayne L. Furman, Michael M Meagher, Fariba Navid, Victor M. Santana> ;Mabs. 2020 Jul 9
11 citations
Phase I expansion cohort to evaluate the combination of bevacizumab, sorafenib and low-dose cyclophosphamide in children and young adults with refractory or recurrent ...
Sara M. Federico, Kenneth J. Caldwell, Mary Beth McCarville, Vinay M. Daryani, Clinton F. Stewart, Shenghua Mao, Jianrong Wu, Andrew M. Davidoff, Victor M. Santana, Wa...> ;European Journal of Cancer. 2020 Jun 1
9 citations
A phase 1 trial of everolimus and bevacizumab in children with recurrent solid tumors
Victor M. Santana, Natasha Sahr, Ruth G. Tatevossian, Sujuan Jia, Olivia Campagne, April Sykes, Clinton F. Stewart, Wayne L. Furman, Lisa M. McGregor> ;Cancer. 2020 Apr 15
12 citations
Longitudinal NK cell kinetics and cytotoxicity in children with neuroblastoma enrolled in a clinical phase II trial
Rosa Nguyen, Natasha Sahr, April Sykes, Mary Beth McCarville, Sara M. Federico, Amanda Sooter, David Cullins, Barbara Rooney, William E. Janssen, Aimee C Talleur, Bran...> ;Journal for Immunotherapy of Cancer. 2020 Mar 1
12 citations
Clinically ascertained health outcomes, quality of life, and social attainment among adult survivors of neuroblastoma: A report from the St. Jude Lifetime Cohort
Carmen L. Wilson, Tara M. Brinkman, Cathleen Marie Cook, Sujuan Huang, Geehong Hyun, Daniel M. Green, Wayne L. Furman, Nickhill Bhakta, Matthew J. Ehrhardt, Matthew J....> ;Cancer. 2020 Mar 15
19 citations
Desmoplastic Small Round Cell Tumor: Long-Term Complications After Cytoreduction and Hyperthermic Intraperitoneal Chemotherapy
Zachary E. Stiles, Andrew J. Murphy, Doralina L. Anghelescu, Christina-Lin Brown, Andrew M. Davidoff, Paxton V. Dickson, Evan S. Glazer, Michael W. Bishop, Wayne L. Fu...> ;Annals of Surgical Oncology. 2020 Jan 1
10 citations
Impact of MYCN status on response of high-risk neuroblastoma to neoadjuvant chemotherapy.
David Yanishevski, M. Beth McCarville, Mikhail Doubrovin, Hannah R. Spiegl, Xiwen Zhao, Zhaohua Lu, Sara M. Federico, Wayne L. Furman, Andrew J. Murphy, Andrew M. Davi...> ;Journal of Pediatric Surgery. 2020 Jan 1
13 citations
Biochemical testing for neuroblastoma using plasma free 3-O-methyldopa, 3-methoxytyramine, and normetanephrine.
Mirko Peitzsch, Elizabeth R. Butch, Elizabeth A. Lovorn, Anastasios Mangelis, Wayne L. Furman, Victor M. Santana, Barbara Hero, Frank Berthold, Barry L. Shulkin, Angel...> ;Pediatric Blood & Cancer. 2020 Feb 1
2 citations
Secondary hemophagocytic syndrome after autologous hematopoietic cell transplant and immune therapy for neuroblastoma.
Rebecca Epperly, Wayne L. Furman, Melissa Hines, Teresa Santiago, Ying Li, Renee Madden, Ewelina Mamcarz, David Cervi, Sara M. Federico, Brandon M. Triplett, Aimee C T...> ;Pediatric Blood & Cancer. 2019 Nov 1
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Journal Articles

Serum ALT Elevations in Survivors of Childhood Cancer. A Report from the St. Jude Lifetime Cohort Study
Matthew J Krasin, Sima Jeha, Daniel M Green, Melissa M Hudson, Wayne L Furman, Michael W Bishop, Hepatology

Press Mentions

Novel Monoclonal Antibody Could Help Revolutionize Treatment of Children with High-Risk NeuroblastomaDecember 6th, 2021
New Treatment Offers Hope for Kids with Deadly Nerve CancerOctober 10th, 2019
Findings About Children’s Solid Tumors Are Sparking New TherapiesApril 9th, 2019
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