WenJiangMD

PubMed

• Bio-integrated scaffold facilitates large bone regeneration dominated by endochondral ossification.
  Sun, L., Niu, H., Wu, Y., Dong, S., Li, X., Kim, B., Liu, C., Ma, Y., Yuan, Y., Jiang, W.> ;Bioactive Materials. 2024 May 1
• A Cancer Nanovaccine Based on an FeAl-Layered Double Hydroxide Framework for Reactive Oxygen Species-Augmented Metalloimmunotherapy.
  Mengyu Chang, Man Wang, Bin Liu, Wenbin Zhong, Deblin Jana, Yifan Wang, Shiyan Dong, Abin Antony, Chunxia Li, Yuhui Liu, Zhongqi Zhao, Jun Lin, Wen Jiang, Yanli Zhao> ;ACS Nano. 2024 Mar 19
• Radiation Synergizes with IL2/IL15 Stimulation to Enhance Innate Immune Activation and Antitumor Immunity.
  Xuefeng Li, Yifan Wang, DaeYong Lee, Shiyan Dong, Abin Antony, Carl Walkey, Betty Y S Kim, Wen Jiang, Huntoon, K.> ;Molecular Cancer Therapeutics. 2024 Mar 4
• 2 citations
  Engineering a tunable micropattern-array assay to sort single extracellular vesicles and particles to detect RNA and protein in situ.
  Jingjing Zhang, Xilal Y Rima, Xinyu Wang, Luong T H Nguyen, Kristin Huntoon, Yifan Ma, Paola Loreto Palacio, Kim Truc Nguyen, Karunya Albert, Minh-Dao Duong-Thi, Nicol...> ;Journal of Extracellular Vesicles. 2023 Nov 1
• 4 citations
  Dual targeted extracellular vesicles regulate oncogenic genes in advanced pancreatic cancer.
  Chi-Ling Chiang, Yifan Ma, Ya-Chin Hou, Junjie Pan, Sin-Yu Chen, Ming-Hsien Chien, Zhi-Xuan Zhang, Wei-Hsiang Hsu, Xinyu Wang, Jingjing Zhang, Hong Li, Lili Sun, Shann...> ;Nature Communications. 2023 Oct 23
• 5 citations
  Adaptive design of mRNA-loaded extracellular vesicles for targeted immunotherapy of cancer.
  Shiyan Dong, Xuan Liu, Ye Bi, Yifan Wang, Abin Antony, DaeYong Lee, Kristin Huntoon, Seongdong Jeong, Yifan Ma, Xuefeng Li, Weiye Deng, Benjamin R Schrank, Adam J Grip...> ;Nature Communications. 2023 Oct 19
• 2 citations
  Age-associated disparity in phagocytic clearance affects the efficacy of cancer nanotherapeutics.
  Yifan Wang, Weiye Deng, DaeYong Lee, Long Yan, Yifei Lu, Shiyan Dong, Kristin Huntoon, Abin Antony, Xuefeng Li, Rui Ye, Yan Zhao, Feiyan Zhao, Benjamin R Schrank, Jong...> ;Nature Nanotechnology. 2024 Feb 1
• 3 citations
  Targeting phagocytosis to enhance antitumor immunity.
  Kristin Huntoon, DaeYong Lee, Shiyan Dong, Abin Antony, Betty Y S Kim, Wen Jiang> ;Trends in Cancer. 2023 Aug 1
• 3 citations
  Waking immune-resistant tumors with neddylation.
  Kristin Huntoon, Wen Jiang, Betty Ys Kim> ;The Journal of Clinical Investigation. 2023 Feb 15
• 25 citations
  Intradermally delivered mRNA-encapsulating extracellular vesicles for collagen-replacement therapy.
  Yi You, Yu Tian, Zhaogang Yang, Junfeng Shi, Kwang Joo Kwak, Yuhao Tong, Andreanne Poppy Estania, Jianhong Cao, Wei-Hsiang Hsu, Yutong Liu, Chi-Ling Chiang, Benjamin R...> ;Nature Biomedical Engineering. 2023 Jul 1
• 1 citations
  Association of circulating markers with cognitive decline after radiation therapy for brain metastasis.
  Kristin Huntoon, S Keith Anderson, Karla V Ballman, Erin Twohy, Katharine Dooley, Wen Jiang, Yi An, Jing Li, Christina von Roemeling, Yaqing Qie, Owen A Ross, Jane H C...> ;Neuro-Oncology. 2023 Jun 2
• 12 citations
  Immunological conversion of solid tumours using a bispecific nanobioconjugate for cancer immunotherapy.
  Yifei Lu, Kristin Huntoon, DaeYong Lee, Yifan Wang, JongHoon Ha, Yaqing Qie, Xuefeng Li, Benjamin R Schrank, Shiyan Dong, Thomas D Gallup, Minjeong Kang, Hai Zhao, Yi ...> ;Nature Nanotechnology. 2022 Dec 1
• 10 citations
  Neoadjuvant toripalimab combined with gemcitabine and cisplatin in resectable locally advanced head and neck squamous cell carcinoma (NeoTGP01): An open label, single-...
  Xiaotao Huang, Qiaodan Liu, Guihua Zhong, Yingpeng Peng, Ye Liu, Lizhong Liang, Haiyu Hong, Weineng Feng, Shuang Yang, Yaqin Zhang, Shiping Xian, Zhanyu Li, Yuling Zho...> ;Journal of Experimental & Clinical Cancer Research. 2022 Oct 12
• 6 citations
  Hybrid Nanofibrous Composites with Anisotropic Mechanics and Architecture for Tendon/Ligament Repair and Regeneration.
  Jun Li, Chao Xue, Hao Wang, Shiyan Dong, Zhaogang Yang, Yuting Cao, Binan Zhao, Biao Cheng, Xianrui Xie, Xiumei Mo, Wen Jiang, Hengfeng Yuan, Jianfeng Pan> ;Small. 2022 Jul 1
• Cancer stem cells, not bulk tumor cells, determine mechanisms of resistance to SMO inhibitors.
  Joshy George, Yaohui Chen, Nourhan Abdelfattah, Keiko Yamamoto, Thomas D Gallup, Scott I Adamson, Brad Rybinski, Anuj Srivastava, Parveen Kumar, Min Gyu Lee, David S B...> ;Cancer Research Communications. 2022 Jun 1
• 28 citations
  Multicenter phase II trial of Camrelizumab combined with Apatinib and Eribulin in heavily pretreated patients with advanced triple-negative breast cancer.
  Jieqiong Liu, Ying Wang, Zhenluan Tian, Ying Lin, Hengyu Li, Zhaowen Zhu, Qiang Liu, Shicheng Su, Yinduo Zeng, Weijuan Jia, Yaping Yang, Shengqiang Xu, Herui Yao, Wen ...> ;Nature Communications. 2022 May 31
• 49 citations
  Cancer immunotherapy based on image-guided STING activation by nucleotide nanocomplex-decorated ultrasound microbubbles.
  Xuefeng Li, Sina Khorsandi, Yifan Wang, Julien Santelli, Kristin Huntoon, Nhu Nguyen, Mingming Yang, DaeYong Lee, Yifei Lu, Ruoqi Gao, Betty Y S Kim, Caroline de Graci...> ;Nature Nanotechnology. 2022 Aug 1
• 17 citations
  Dual-Loaded Liposomes Tagged with Hyaluronic Acid Have Synergistic Effects in Triple-Negative Breast Cancer.
  Shiyan Dong, Ye Bi, Xiangshi Sun, Yarong Zhao, Rongze Sun, Fei Hao, Yating Sun, Yifan Wang, Xuefeng Li, Weiye Deng, Xuan Liu, JongHoon Ha, Lirong Teng, Ping Gong, Jing...> ;Small. 2022 Apr 1
• 101 citations
  Single-cell analysis of human glioma and immune cells identifies S100A4 as an immunotherapy target.
  Nourhan Abdelfattah, Parveen Kumar, Caiyi Wang, Jia-Shiun Leu, William F Flynn, Ruli Gao, David S Baskin, Kumar Pichumani, Omkar B Ijare, Stephanie L Wood, Suzanne Z P...> ;Nature Communications. 2022 Feb 9
• Racial and Ethnic Differences in Genomic Profiling of Early Onset Colorectal Cancer.
  David M Hein, Weiye Deng, MaryLena Bleile, Syed Ali Kazmi, Brooke Rhead, Francisco M De La Vega, Amy L Jones, Radhika Kainthla, Wen Jiang, Brandi Cantarel, Nina N Sanford> ;Journal of the National Cancer Institute. 2022 May 9
• 26 citations
  Intelligent photothermal dendritic cells restart the cancer immunity cycle through enhanced immunogenic cell death
  Zhihong Sun, Guanjun Deng, Xinghua Peng, Xiuli Xu, Lanlan Liu, Jiaofeng Peng, Yifan Ma, Pengfei Zhang, Austin Wen, Yifan Wang, Zhaogang Yang, Gong Ping, Wen Jiang, Lin...> ;Biomaterials. 2021 Oct 26
• 4 citations
  Potassium Iodide Nanoparticles Enhance Radiotherapy against Breast Cancer by Exploiting the Sodium-Iodide Symporter.
  Benjamin Cline, Wen Jiang, Chaebin Lee, Zhengwei Cao, Xueyuan Yang, Shuyue Zhan, Harrison Byron Chong, Tao Zhang, Zhaoguo Han, Xuedan Wu, Li Yao, Hui Wang, Weizhong Zh...> ;ACS Nano. 2021 Oct 25
• 7 citations
  A Modified Nucleoside 6-Thio-2'-Deoxyguanosine Exhibits Antitumor Activity in Gliomas.
  Shengnan Yu, Shiyou Wei, Milan R. Savani, Xiang Lin, Kuang Du, Ilgen Mender, Silvia Siteni, Themistoklis Vasilopoulos, Zachary J. Reitman, Yin Ku, Di Wu, Hao Liu, Meng...> ;Clinical Cancer Research. 2021 Sep 30
• 193 citations
  Proteogenomic characterization of pancreatic ductal adenocarcinoma
  Liwei Cao, Chen Huang, Daniel Cui Zhou, Yingwei Hu, T. Mamie Lih, Sara R. Savage, Karsten Krug, David J. Clark, Michael Schnaubelt, Lijun Chen, Felipe da Veiga Leprevo...> ;Cell. 2021 Sep 16
• 13 citations
  Emerging Biological Functions of IL-17A: A New Target in Chronic Obstructive Pulmonary Disease?
  Meiling Liu, Kang Wu, Jinduan Lin, Qingqiang Xie, Yuan Liu, Yin Huang, Jun Zeng, Zhaogang Yang, Yifan Wang, Shiyan Dong, Weiye Deng, Mingming Yang, Song Wu, Wen Jiang,...> ;Frontiers in Pharmacology. 2021 Jul 2
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Journal Articles

• Therapeutic remodeling of the tumor microenvironment enhances nanoparticle delivery  
  Chen Y, Liu X, Yuan H, von Roemeling CA, Qie Y, Knight JA, Wang Y, Yun K, Jiang W, Kim BYS, Adv. Science, 1/1/2019
• Multi-institutional Investigation: Circulating CD4: CD8 ratio is a prognosticator of response to total skin electron beam radiation in mycosis fungoides  
  An Y, Jiang W (co-first), Andraos TY, Reddy JP, Yehia ZA, Lloyd S, Duvic M, D'Souza NM, Milgrom SA, Pinnix CC, Oki Y, Smith GL, Wilson LD, Dabaja BS, Radiother Oncol, 1/1/2019
• The Reciprocity Between Radiotherapy and Cancer Immunotherapy  
  Wen Jiang, Jing Li, Clinical Cancer Research
• The reciprocity cancer immunotherapy and radiotherapy  
  Wang Y, Liu ZG, Huang YH, Li J, Kim BYS, Story MD, Jiang W, Clinical Cancer Research, 1/1/2018
• Tumor vasculature: A new target for cancer immunotherapy  
  Liu Z, Yuan H, Wang Y, Yan Z, Huang YH, Kim BYS, Jiang W, Trends Pharm. Sci. (Cell Press), 1/1/2018
• Immune modulating nanomedicine for cancer therapy  
  Liu Z, Jiang W, Nam J, Moon JJ, Kim, BYS, Nano Letters, 1/1/2018
• Mutant LKB1 confers enhanced radiosensitization in combination with trametinib in KRAS-mutant non-small cell lung cancer  
  Wang Y, Li N, Jiang W, Deng W, Ye R, Xu C, Qiao Y, Sharma A, Zhang M, Hung MC, Lin SH, Clinical Cancer Research, 1/1/2018
• Efficacy and Toxic Effects of Cancer Immunotherapy Combinations: A Double-Edged Sword  
  Tang C, Jiang W, Yap TA, JAMA Oncology, 1/1/2018
• Increased vessel perfusion predicts the therapeutic efficacy of immune checkpoint blockade  
  Zheng X, Fang Z, Wang X, Zhang C, Yin R, Wen C, Liu X, Deng S, Zhou P, Hu H, Chen X, Wang X, Zhao Y, Xin L, Lin *SH, Kim BYS, Jiang W, Wu Q, Huang YH, Journal of Clinical Investigation, 1/1/2018
• Improving immune-vascular crosstalk for cancer immunotherapy  
  Huang YH, Kim BYS, Chan CK, Hahn SM, Weissman IL, Jiang W, Nature Rev Immunology, 1/1/2018
• Combination of Immunotherapy and Radiotherapy for Cancer Treatment: Current Progress and Future Directions  
  Wang Y, Deng W, Li N, Neri S, Sharma A, Jiang W, Lin SH, Front Pharmacol, 1/1/2018
• Lymphocyte-Sparing Effect of Proton Therapy in Esophageal Cancer Patients Treated with Definitive Chemoradiation  
  Fang P, Shiraishi Y, Jiang W, Song J, Hobbs BP, Lin SH, Int J Particle Ther, 1/1/2018
• High Lymphocyte Count during Neoadjuvant Chemoradiotherapy is Associated with Improved Pathologic Complete Response in Esophageal Cancer  
  Fang P, Jiang W, Rajayogesh D, Xu C, Krishnan SK, Mohan R, Koong AC, Hsu CC, Lin SH, Radiotherapy and Oncology, 1/1/2018
• Pre-treatment Neutrophil/Lymphocyte Ratio and Platelet/Lymphocyte Ratio are Prognostic of Progression in Early Stage Classical Hodgkin Lymphoma  
  Reddy JP, Hernandez M, Gunther JR, Dabaja BS, Martin GV, Jiang W, Akhtari M, Allen PK, Atkinson BJ, Smith GL, Pinnix CC, Milgrom SA, Yehia ZA, Osborne EM, Oki Y, Lee H..., Br J Haematology, 1/1/2018
• RAD50 expression is associated with poor clinical outcomes after radiotherapy in resected non-small cell lung cancer  
  Wang Y, Gudikote J, Yan J, Deng W, Jiang W, Li N, Ye R, Hobbs BP, Wang J, Swisher SG, Fujimoto J, Wistuba II, Komaki R, Heymach JV, Lin SH, Clin Cancer Res, 1/1/2017
• S100A4 is a biomarker and regulator of glioma stem cells that is critical for mesenchymal transition in glioblastoma  
  Chow KH, Park HJ, George J, Yamamoto K, Gallup AD, Graber J, Chen YX, Jiang W, Steindler D, Neilson EG, Kim BYS, Yun K, Cancer Research, 1/1/2017
• Multivalent Bi-Specific Nano-Bioconjugate Engager for Targeted Cancer Immunotherapy  
  Yuan H, Jiang W, von Roemeling CA, Qie Y, Liu X, Chen Y, Wharen RE, Yun K, Bu G, Knutson KL, Kim BYS, Nature Nanotechnology, 1/1/2017
• Designing next generation cancer nanomedicine for immuno-oncology  
  Jiang W, von Roemeling C, Qie Y, Chen Y, Liu X, Chen J, Kim BYS, Nature Biomed Eng, 1/1/2017
• Lessons from Immuno-Oncology: An New Era for Cancer Nanomedicine?  
  Jiang W, Yuan H, Chan CK, von Roemeling C, Yan Z, Weissman IL, Kim BYS, Nature Rev Drug Discovery, 1/1/2017
• Breaking Down the Barriers to Precision Cancer Nanomedicine  
  von Roemling C, Jiang W, Chan CK, Weissman IL, Kim BYS, Trends in Biotechnol (Cell Press), 1/1/2017
• Estimating Survival in Melanoma Patients with Brain Metastases: An Update of the Graded Prognostic Assessment for Melanoma Using Molecular Markers (Melanoma-molGPA)  
  Sperduto PW, Jiang W, Brown PD, Braunstein S, Sneed P, Wattson DA, Shih HA, Bangdiwala A, Shanley R, Lockney NA, Beal K, Lou E, Amatruda T, Sperduto WA, Kirkpatrick JP..., Int J Rad Onc Biol Phys, 1/1/2017
• Lymphocyte Nadir and Esophageal Cancer Survival Outcomes Following Chemoradiotherapy  
  Davuluri R, Jiang W, Fang P, Xu C, Komaki R, Gomez DR, Welsh JW, Cox JD, Crane CH, Hsu CC, Lin SH, Int J Rad Onc Biol Phys, 1/1/2017
• Radiation necrosis with stereotactic radiosurgery combined with CTLA-4 blockade and PD-1 inhibition for treatment of intracranial disease in metastatic melanoma  
  Fang P, Jiang W, Allen P, Glitza I, Guha N, Hwu P, Ghia A, Phan J, Mahajan A, Tawbi H, Li J, J. Neuro-Oncol, 1/1/2017
• The Prognostic Value of BRAF, cKIT, and NRAS Mutations in Melanoma Patients with Brain Metastases  
  Sperduto PW, Jiang W, Brown PD, Braunstein S, Sneed P, Wattson D, Shih HA, Bangdiwala A, Shanley R, Lockney N, Beal K, Lou E, Amatruda T, Sperduto W, Kirkpatrick JP, Y..., Int J Rad Onc Biol Phys, 1/1/2017
• A Predictive Model for Distinguishing Radiation Necrosis from Tumor Progression after Gamma Knife Radiosurgery based on Radiomics Features from Magnetic Resonance Images  
  Zhang Z, Yang J, Ho A, Jiang W, Wang XA, Brown PD, Guha-Thakurta N, Ferguson SD, Fave X, Zhang L, Mackin D, Court LE, Jing Li, Eur Radiology, 1/1/2017
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Books/Book Chapters

• Contemporary Management of Intracranial Gliomas 
  Chapter: Perspectives of nanotechnology in the management of gliomas. 
  Yoon JW, Jiang W, Rutka JTR, Huang Y, Kim BYSEditors: Chernov MF, Muragaki Y, Kesari S, McCutcheon IE.Karger Medical and Scientific Publishers, BerlinEdition 1st,2015
• Therapeutic Micro/Nanotechnology 
  Chapter: Engineering biocompatible quantum dots for real-time, ultrasensitive biological imaging and detection. 
  Page 137 - 156Jiang W, Singhal A, Fischer H, Mardyani S, Chan WCWEditors: Bhatia S, and Desai T.Kluwer Publishing2006
• Biological Nanostructures and Applications of Nanostructures in Biology 
  Chapter: Bioinspired approaches to build nanoscale devices. 
  Page 149 - 161Mardyani S, Jiang W, Lai J, Zhang J, Chan, WCWEditors: Stoscio M, and Dutta M.Kluwer Publishing2004

Abstracts/Posters

• Multiplex in situ immunoprofiling and survival outcomes in non-small cell lung cancer.
  Lin SH, Mansfield JR, Rao X, Jiang W, Fang P, Roman K, Wang C, Komaki R, Hahn S, Swisher SG, Fujimoto J, Wistuba I, Wang J, Hoyt CC, AACR (American Association for Cancer Research) Annual Meeting, New Orleans, LA, 1/1/2016
• Circulating myeloid precursor profile as potential marker to differentiate radiation changes from tumor recurrence after brain stereotactic radiosurgery.
  Jiang W, AACR (American Association for Cancer Research) Annual Meeting, Philadelphia, PA, 1/1/2015

Lectures

• Selective macrophage evading nanomedicine enables enhanced delivery and therapeutic efficacy of anti-cancer agents against solid tumors. 
  Mount Snow, VT - 1/1/2017
• CD4:CD8 Ratio in Mycosis Fungoides: Prognostic and Predictive Value of Circulating T lymphocyte Subsets for Outcomes after Total Skin Electron Beam Radiation. 
  Boston, MA - 1/1/2016
• Circulating Lymphocyte Count During Neoadjuvant Chemoradiation Therapy for Esophageal Cancer as a Predictive Biomarker of Pathologic Complete Response. 
  Boston, MA - 1/1/2016
• Temporally-Dependent Intracranial Control of Melanoma Brain Metastasis by Stereotactic Radiation Therapy in Patients Treated With Immune Checkpoint Blockade. 
  San Antonio, TX - 1/1/2015
• Microenvironmental modulation improves nanomedicine delivery into brain tumors. 
  San Antonio, TX - 1/1/2015
• Temporally dependent intracranial control of melanoma brain metastasis by stereotactic radiotherapy in patients treated with immune-checkpoint blockade. 
  Hunan, China - 1/1/2015
• Idh1 Status As a Complementary Marker Formalignant Astrocytomas with Limited Surgical Specimen. 
  Seoul, Korea - 1/1/2013
• Vascular normalization enhances the delivery of nanoparticle carriers into solid tumors. 
  Stanford, CA - 1/1/2010
• Live cell labeling and imaging with intracellularly delivered quantum dot probes. 
  Boston, MA - 1/1/2009
• Nanotechnology and brain tumors. 
  Vancouver, British Columbia, Canada - 1/1/2009
• Size-control of nanoparticle intracellular delivery and its effects. 
  Toronto, Ontario, Canada - 1/1/2008
• Controlling cell fate using nanoparticle geometry. 
  Orlando, FL - 1/1/2008
• Biodegradable quantum dot nanocomposites for intracellular delivery and imaging of live cells. 
  San Francisco, CA - 1/1/2008
• Engineered nanoparticles for enhanced therapeutic and cellular responses 
  Vancouver, British Columbia, Canada - 1/1/2008
• Nanoparticle-mediated cellular response is size dependent. 
  Toronto, Ontario, Canada - 1/1/2008
• Optimizing near-IR CdTexSe1-x alloyed quantum dots for biomedical imaging. 
  Chicago, IL - 1/1/2006
• Novel quantum dot-antibody probes for in vivo fluorescence endoscopic detection of precancerous lesions of the gastrointestinal tract. 
  Toronto, Ontario, Canada - 1/1/2006
• Near-infrared emitting quantum dots for enhanced bioimaging. 
  Montreal, Quebec, Canada - 1/1/2005
• Nanocrystal contrast agents for enhanced biological imaging. 
  Toronto, Ontario, Canada - 1/1/2005
• Multiplexed quantum dot fluorescence imaging by In Vivo targeting of epidermal growth factor receptor (EGFR) and villin expression in Barrett's esophagus (BE) surgical... 
  Washington, DC - 1/1/2005
• Surface plasmon coupled emission of quantum dots. 
  San Diego, CA - 1/1/2004
• Surface modification of semiconductor quantum dots for biological imaging. 
  Toronto, Ontario, Canada - 1/1/2004
• Ultrasensitive molecular imaging using quantum dots-bioconjugates. 
  Indianapolis, IN - 1/1/2004
• Biological applications of semiconductor quantum dots. 
  Toronto, Ontario, Canada - 1/1/2004
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