WendyLFrankelMD

PubMed

• Comparing Accuracy of Helicobacter pylori Identification Using Traditional Hematoxylin and Eosin-Stained Glass Slides With Digital Whole Slide Imaging.
  Wei Chen, Jennifer Ziebell, Vidya Arole, Bryce Parkinson, Lianbo Yu, Harrison Dai, Wendy L Frankel, Martha Yearsley, Ashwini Esnakula, Shaoli Sun, Denise Gamble, Jenni...> ;Laboratory Investigation; a Journal of Technical Methods and Pathology. 2024 Jan 1
• Ampulla of Vater biopsies: A retrospective 10-year, single-institution study.
  Denise Gamble, Wendy L Frankel, Martha M Yearsley, Wei Chen> ;Annals of Diagnostic Pathology. 2023 Dec 1
• 1 citations
  Mismatch repair protein status of non-neoplastic uterine and intestinal mucosa in patients with Lynch syndrome and double somatic mismatch repair protein mutations.
  C Eric Freitag, Wei Chen, Rachel Pearlman, Heather Hampel, Peter P Stanich, Casey M Cosgrove, Eric Q Konnick, Colin C Pritchard, Wendy L Frankel> ;Human Pathology. 2023 Jul 1
• 4 citations
  Neuropeptide Y, a paracrine factor secreted by cancer cells, is an independent regulator of angiogenesis in colon cancer.
  Debanjan Chakroborty, Sandeep Goswami, Hao Fan, Wendy L Frankel, Sujit Basu, Chandrani Sarkar> ;British Journal of Cancer. 2022 Nov 1
• 87 citations
  Efficacy of Preoperative mFOLFIRINOX vs mFOLFIRINOX Plus Hypofractionated Radiotherapy for Borderline Resectable Adenocarcinoma of the Pancreas: The A021501 Phase 2 Ra...
  Matthew H G Katz, Qian Shi, Jeff Meyers, Joseph M Herman, Michael Chuong, Brian M Wolpin, Syed Ahmad, Robert Marsh, Larry Schwartz, Spencer Behr, Wendy L Frankel, Eric...> ;JAMA Oncology. 2022 Sep 1
• Universal tumor screening for lynch syndrome on colorectal cancer biopsies impacts surgical treatment decisions.
  Jennifer Vazzano, Jewel Tomlinson, Peter P Stanich, Rachel Pearlman, Matthew F Kalady, Wei Chen, Heather Hampel, Wendy L Frankel> ;Familial Cancer. 2023 Jan 1
• 44 citations
  Randomized Phase II Study of PET Response-Adapted Combined Modality Therapy for Esophageal Cancer: Mature Results of the CALGB 80803 (Alliance) Trial.
  Karyn A. Goodman, Fang-Shu Ou, Nathan Hall, Tanios Bekaii-Saab, Briant Fruth, Erin Twohy, Michael O. Meyers, Daniel J. Boffa, Kisha Mitchell, Wendy L. Frankel, Donna N...> ;Journal of Clinical Oncology. 2021 Jun 2
• 35 citations
  Prospective Statewide Study of Universal Screening for Hereditary Colorectal Cancer: The Ohio Colorectal Cancer Prevention Initiative.
  Rachel Pearlman, Wendy L. Frankel, Benjamin Swanson, Dan Jones, Weiqiang Zhao, Ahmet Yilmaz, Kristin Miller, Jason Bacher, Christopher Bigley, Lori Nelsen, Paul J. Goo...> ;JCO Precision Oncology. 2021 May 5
• 26 citations
  Digital Pathology Initiatives and Experience of a Large Academic Institution During the Coronavirus Disease 2019 (COVID-19) Pandemic.
  Giovanni Lujan, Johanna Savage, Arwa Shana'ah, Martha Yearsley, Diana L. Thomas, Patricia Allenby, Jose Otero, Abberly Lott Limbach, Xiaoyan Cui, Rachel T. Scarl, Tann...> ;Archives of Pathology & Laboratory Medicine. 2021 Sep 1
• 1 citations
  Pancreatic Frozen Section Guides Operative Management With Few Deferrals and Errors.
  Jesus A. Chavez, Wei Chen, C. Eric Freitag, Wendy L. Frankel> ;Archives of Pathology & Laboratory Medicine. 2021 Mar 26
• 2 citations
  Using Endoscopic Optical Coherence Tomography to Detect and Treat Early-Stage Pancreatic Cancers.
  L Lu, Zhilin Hu, Wendy L. Frankel, Rulong Shen, Wei Chen, Xueliang Pan, John C. Grecula, Mark Bloomston, Mary Dillhoff> ;Frontiers in Oncology. 2021 Mar 15
• 4 citations
  Morphologic changes associated with neoadjuvant-treated pancreatic ductal adenocarcinoma and comparison of two tumor regression grading systems.
  Jennifer Vazzano, Wendy L. Frankel, Adam R. Wolfe, Terence M. Williams, Wei Chen> ;Human Pathology. 2021 Mar 1
• 17 citations
  Activation of the RAS pathway through uncommon BRAF mutations in mucinous pancreatic cysts without KRAS mutation.
  Rongqin Ren, Somashekar G. Krishna, Wei Chen, Wendy L. Frankel, Rulong Shen, Weiqiang Zhao, Matthew R. Avenarius, Jason Garee, Sean Caruthers, Dan Jones> ;Modern Pathology. 2021 Feb 1
• 19 citations
  Histopathological diagnosis of tumour deposits in colorectal cancer: a Delphi consensus study
  Amy Lord, Gina Brown, Muti Abulafi, Adrian C Bateman, Wendy L. Frankel, Robert D. Goldin, Purva Gopal, Richard Kirsch, Maurice B. Loughrey, Bruno Märkl, Brendan Moran,...> ;Histopathology. 2021 Jan 28
• 21 citations
  Double somatic mismatch repair gene pathogenic variants as common as Lynch syndrome among endometrial cancer patients
  Heather Hampel, Rachel Pearlman, Albert de la Chapelle, Colin C. Pritchard, Weiqiang Zhao, Dan Jones, Ahmet Yilmaz, Wei Chen, Wendy L. Frankel, Adrian A. Suarez, Casey...> ;Gynecologic Oncology. 2021 Jan 1
• 13 citations
  Unexpected expression of mismatch repair protein is more commonly seen with pathogenic missense than with other mutations in Lynch syndrome.
  Wei Chen, Heather Hampel, Rachel Pearlman, Dan Jones, Weiqiang Zhao, Mohammed Alsomali, Deborah Knight, Wendy L. Frankel> ;Human Pathology. 2020 Sep 1
• 27 citations
  Neoadjuvant-modified FOLFIRINOX vs nab-paclitaxel plus gemcitabine for borderline resectable or locally advanced pancreatic cancer patients who achieved surgical resec...
  Adam R. Wolfe, Dhivya Prabhakar, Vedat O. Yildiz, Jordan M. Cloyd, Mary Dillhoff, Laith Abushahin, Dayssy Alexandra Diaz, Eric D. Miller, Wei Chen, Wendy L. Frankel, A...> ;Cancer Medicine. 2020 Jul 1
• 1 citations
  Perineural invasion predicts for locoregional failure in patients with oesophageal adenocarcinoma treated with neoadjuvant chemoradiotherapy
  Ankur K. Patel, Xueliang Pan, Diana M Vila, Wendy L. Frankel, Wei Chen, Kyle A. Perry, Robert E. Merritt, Desmond M. D’Souza, Evan Wuthrick, Terence M. Williams> ;Journal of Clinical Pathology. 2021 Apr 1
• 12 citations
  Programmed cell death‐1 (PD‐1) and programmed death‐ligand 1 (PD‐L1) expression in PD‐1 inhibitor‐associated colitis and its mimics
  Clarissa A. Cassol, Dwight H. Owen, Kari Kendra, Juarez R. Braga, Wendy L. Frankel, Christina A. Arnold> ;Histopathology. 2020 Aug 1
• 6 citations
  A microRNA-based signature predicts local-regional failure and overall survival after pancreatic cancer resection.
  Adam R. Wolfe, Patrick Wald, Amy Webb, Nikhil Sebastian, Steve Walston, Ryan Robb, Wei Chen, Marall Vedaie, Mary Dillhoff, Wendy L. Frankel, Wooil Kwon, Jin-Young Jang...> ;Oncotarget. 2020 Mar 10
• Author Correction: A modular cGAN classification framework: Application to colorectal tumor detection.
  Thomas E. Tavolara, M. Khalid Khan Niazi, Vidya Arole, Wei Chen, Wendy L. Frankel, Metin N. Gurcan> ;Scientific Reports. 2020 Feb 6
• 9 citations
  Tumor Budding Detection System in Whole Slide Pathology Images.
  Mohammad Faizal Ahmad Fauzi, Wei Chen, Debbie Knight, Heather Hampel, Wendy L. Frankel, Metin N. Gurcan> ;Journal of Medical Systems. 2020 Feb 1
• 16 citations
  MSH6 immunohistochemical heterogeneity in colorectal cancer: comparative sequencing from different tumor areas.
  Wei Chen, Rachel Pearlman, Heather Hampel, Colin C. Pritchard, Michael Markow, Christina A. Arnold, Deborah Knight, Wendy L. Frankel> ;Human Pathology. 2020 Feb 1
• 7 citations
  A modular cGAN classification framework: Application to colorectal tumor detection.
  Thomas E. Tavolara, M. Khalid Khan Niazi, Vidya Arole, Wei Chen, Wendy L. Frankel, Metin N. Gurcan> ;Scientific Reports. 2019 Dec 12
• 1 citations
  Multinucleated stromal giant cells in the gastroesophageal junctional and gastric mucosa: a retrospective study.
  Taha Sachak, Wendy L. Frankel, Christina A. Arnold, Wei Chen> ;Diagnostic Pathology. 2019 Jul 27
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Journal Articles

• Two-Stain Immunohistochemical Screening for Lynch Syndrome in Colorectal Cancer May Fail to Detect Mismatch Repair Deficiency  
  Heather Hampel, Wei Chen, Rachel Pearlman, Colin C Pritchard, Christina A Arnold, Wendy L Frankel, Nature
• Prostate cancer incidence in males with Lynch syndrome  
  Haraldsdottir S, Hampel H, Wei L, Wu C, Frankel WL, Bekaii-Saab T, de la Chapelle A, Goldberg R, Genetics in Medicine, 1/16/2014
• A differential microRNA profile distinguishes cholangiocarcinoma from pancreatic adenocarcinoma  
  Collins AL, Wojcik S, Liu J, Frankel WL, Alder H, Yu L, Schmittgen TD, Croce CM, Bloomston M, Ann Surg Oncol, 1/1/2014
• Different collagen types show distinct rates of increase from early to late stages of Hepatitis-C related liver fibrosis  
  Chen W, Rock JB, Yearsley MM, Ferrell LD, Frankel WL, Hum Pathol, 1/1/2014
• Purinergic Autocrine Regulation of Mechanosensitivity and Serotonin Release in a Human EC Model: ATP-gated P2X3 Channels in EC are Downregulated in Ulcerative Colitis  
  Linan-Rico A, Wunderlich JE, Grants IS, Frankel WL, Xue J, Williams KC, Harzman AE, Enneking JT, Cooke HJ, Christofi FL, Inflamm Bowel, 10/1/2013
• BRAF V600E Mutation Analysis Simplifies the Testing Algorithm for Lynch Syndrome  
  Jin M, Hampel, H, Zhou XP, Schunemann L, Yearsley M, Frankel WL, A J Clin Pathol, 8/1/2013
• Debating Deposits: An Interobserver Variability Study of Lymph Nodes and Pericolonic Tumor Deposits in Colonic Adenocarcinoma  
  Rock JB, Washington MK , Adsay NV, Greenson JK , Montgomery EA, Robert ME, Yantiss RK, Lehman AM, Frankel WL, Arch Pathol Lab Med, 7/31/2013
• Pancreatic cancer-associated stellate cells promote differentiation of myeloid-derived suppressor cells in a STAT3-dependent manner  
  Mace TA, Ameen Z, Collins A, Wojcik S, Mair M, Young GS, Fuchs JR, Eubank TD, Frankel WL, Bekaii-Saab T, Bloomston M, Lesinski GB, Cancer Res, 5/1/2013
• Biologic determinants of tumor reoccurrence in stage II colon cancer: Validation study of the 12-gene Recurrence Score in CALGB 9581  
  Venook AP, Niedzwiecki D, Lopatin M, Lee M, Friedman PN, Frankel WL, Clark-Langone K, Millward C, Shak S, Goldberg RM, Mahmoud NN, Warren RS, Schilsky RL, Bertagnolli MM, J Clin Oncol, 5/1/2013
• Prolapse-Related Changes Are a Confounding Factor in Misdiagnosis of Sessile Serrated Adenomas in the Rectum  
  Huang C, Frankel WL, Doukides T, Zhou XP, Zhao W, Yearsley M, Hum Pathol, 4/1/2013
• Multiplicity and molecular heterogeneity of colorectal carcinomas in individuals with serrated polyposis  
  Rosty C, Walsh MD, Walters RJ, Clendenning M, Pearson SA, Jenkins MA, Win AK, Hopper JL, Sweet K, Frankel WL, Aronson M, Gallinger S, Goldblatt, Tucker K, Greening S, ..., Am J Surg Pathol, 3/1/2013
• Left-sided sessile serrated polyps/adenomas-reply  
  Yearsley MM, Frankel WL, Zhou XP, Zhao W, Hum Pathol, 1/1/2013
• Colorectal-cancer incidence and mortality after screening  
  Oza VM, Frankel WL, Conwell DL, N Engl J Med, 1/1/2013
• Phenotype and Polyp Landscape in Serrated Polyposis Syndrome: A Series of 100 Patients from Genetic Clinics  
  Rosty C, Buchanan DD, Walsh MD, Pearson SA, Pavluk E, Walters RJ, Clendenning M, Spring KJ, Jenkins MA, Win AK, Hopper JL, Sweet K, Frankel WL, Aronson M, Gallinger S,..., Am J Surg Pathol, 6/1/2012
• The Spectrum of Hematological Malignancies Involving the Pancreas: Potential Clinical Mimics of Pancreatic Adenocarcinoma  
  Rock J, Bloomston M, Lozanski G, Frankel WL, Am J Clin Pathol, 3/1/2012
• The Onco-Embryonic Antigen ROR1 Is Expressed By a Variety of Human Cancers  
  Zhang S, Chen L, Wang-Rodriguez J, Zhang L, Cui B, Frankel W, Wu, R, Kipps TJ, Am J Pathol, 1/1/2012
• Cancer Risks for Relatives of Patients with Serrated Polyposis  
  Win AK, Walters RJ, Buchanan DD, Jenkins MA, Sweet K, Frankel WL, de la Chapelle A, McKeone DM, Walsh MD, Clendenning M, Pearson S-A, Pavluk E, Nagler B, Hopper JL, Ga..., Am J Gastroenterol, 1/1/2012
• Impact of disrupting adenosine A(3) receptors (A(3) (-/-)AR) on colonic motility or progression of colitis in the mouse  
  Ren T, Grants I, Alhaj M, McKiernan M, Jacobson M, Hassanain HH, Frankel W, Wunderlich J, Christofi FL, Inflamm Bowel Dis, 8/1/2011
• Cancer & Leukemia Group B Pathology Committee Cancer and Leukemia Group B Pathology Committee guidelines for tissue microarray construction representing multicenter p...  
  Rimm DL, Nielsen TO, Jewell SD, Rohrer DC, Broadwater G, Waldman F, Mitchell KA, Singh B, Tsongalis GJ, Frankel WL, Magliocco AM, Lara JF, Hsi ED, Bleiweiss IJ, Badve ..., J Clin Oncol, 6/1/2011
• Modulation of genetic and epigenetic biomarkers of colorectal cancer in humans by black raspberries: A phase 1 pilot study  
  Wang LS, Arnold M, Huang YW, Sardo C, Seguin C, Martin EW Jr, Huang TH, Riedl K, Schwartz SJ, Frankel WL, Pearl DK, Winston J, Xu Y, Yang GY, Stoner GD, Clin Cancer Res, 1/1/2011
• Protocol for the examination of specimens from patients with carcinoma of the intrahepatic bile ducts  
  Washington MK, Berlin J, Branton PA, Burgart LJ, Carter DK, Compton CC, Frankel WL, Jessup JM, Kakar S, Minsky B, Nakhleh RE, Vauthey HN, Members of the Cancer Committ..., Arch Pathol Lab Med, 1/1/2010
• Protocol for the examination of specimens from patients with carcinoma of the perihilar bile ducts  
  Washington MK, Berlin J, Branton PA, Burgart LJ, Carter DK, Compton CC, Fitzgibbons PL, Frankel WL, Jessup JM, Kakar S, Minsky B, Nakhleh RE, Vauthey JN, Members of th..., Arch Pathol Lab Med, 1/1/2010
• Protocol for the examination of specimens from Patients with carcinoma of the distal extrahepatic bile ducts  
  Washington MK, Berlin J, Branton PA, Burgart LJ, Carter DK, Compton CC, Fitzgibbons PL, Frankel WL, Jessup JM, Kakar S, Minsky B, Nakhleh RE, Vauthey JN, Members of th..., Arch Pathol Lab Med, 1/1/2010
• Protocol for the examination of specimens from patients with neuroendocrine tumors (carcinoid tumors) of the stomach  
  Washington MK, Tang LH, Berlin J, Branton PA, Burgart LJ, Carter DK, Compton CC, Fitzgibbons PL, Frankel WL, Jessup JM, Kakar S, Minsky B, Nakhleh RE, Members of the C..., Arch Pathol Lab Med, 1/1/2010
• Protocol for the examination of specimens from patients with neuroendocrine tumors (carcinoid tumors) of the small intestine and ampulla  
  Washington MK, Tang LH, Berlin J, Branton PA, Burgart LJ, Carter DK, Compton CC, Fitzgibbons PL, Frankel WL, Jessup JM, Kakar S, Minsky B, Nakhleh RE, Members of the C..., Arch Pathol Lab Med, 1/1/2010
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