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William Grizzle, MD, Pathology, Birmingham, AL, University of Alabama Hospital

WilliamEGrizzleMDPh.D.

Pathology • Birmingham, AL

Molecular Genetics, Anatomic Pathology, Clinical Pathology

William E. Grizzle, M.D., Ph.D. Professor of Pathology University of Alabama at Birmingham

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Summary

  • Section Head - Translational Research

Education & Training

  • University of Alabama Medical Center
    University of Alabama Medical CenterResidency, Pathology-Anatomic and Clinical, 1979 - 1980
  • Vanderbilt University Medical Center
    Vanderbilt University Medical CenterResidency, Pathology-Anatomic and Clinical, 1977 - 1979
  • Johns Hopkins University School of Medicine
    Johns Hopkins University School of MedicineClass of 1978
  • Johns Hopkins University School of Medicine
    Johns Hopkins University School of MedicinePost-Doctoral Fellowship, Biomedical Engineering, 1975 - 1975
  • Johns Hopkins University
    Johns Hopkins UniversityPh.D., Biophysics, 1970 - 1975
  • Harvard University
    Harvard UniversityBA, Chemistry and Physics, 1961 - 1965

Certifications & Licensure

  • AL State Medical License
    AL State Medical License 1980 - 2024
  • American Board of Pathology Anatomic Pathology & Clinical Pathology

Awards, Honors, & Recognition

  • Member Steering Committee for Pulmonary Hypertension Breakthrough Initiative (PHBI), 2006, 2012
  • Member Tissue Utiliztion Committee for PHBI, 2006, 2012
  • Consultant, Division of Cancer Biology and Diagnosis National Cancer Institute, 1984, 2012
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Publications & Presentations

PubMed

Journal Articles

  • Optoacoustic Imaging Identifies Ovarian Cancer Using a Microenvironment Targeted Theranostic Wormhole Mesoporous Silica Nanoparticle  
    Peter J Frederick, William E Grizzle, Phillip Chuong, Akiko Chiba, ScienceDirect
  • Confocal 3D DNA cytometry: assessment of required coefficient of variation by computer simulation.  
    Ploeger LS, Belien JAM, Poulin NM, Grizzle W, van Diest PJ, Cell Oncol 2004; 26(3):93-9
  • The biology of incipient, pre-invasive or intraepithelial neoplasia.  
    Grizzle WE, Srivastava S, Manne U, Cancer Biomark 2011;9(1-6):21-39
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Books/Book Chapters

  • Handbook of Immunohistochemistry and in situ Hybridization of Human Carcinomas: Molecular Genetics, Gastrointestinal Carcinoma, and Ovarian Carcinoma. 
    Chapter: Role of immunohistochemical expression of Lewis Y antigen in ovarian carcinoma 
    Page 465 - 471Chhieng DC, Rodriguez-Burford C, Grizzle WEEditors: Hayat MA.Edition 4,
  • Theory and Practice of Histological Techniques. 
    Chapter: Fixation of Tissues 
    Page 53 - 74Grizzle WE, Fredenburgh J, Myers RBEditors: J. Bancroft, M. Gamble.Churchill Livingstone, Edinburgh, United KingdomEdition 6,
  • Theory and Practice of Histological Techniques. 
    Chapter: The Gross Room 
    Page 75 - 82Billings, PE and Grizzle, WEEditors: J. Bancroft, M. Gamble.Churchill Livingstone, Edinburgh, United KingdomEdition 6,
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Abstracts/Posters

  • The Effects of Coumarin and Suramin on the Growth of Malignant Cell Lines.
    Myers RB, Parker MW, Grizzle WE, J Cancer Res Clin Oncol, Springer-Verlag 1994 Suppl 120:S11-S13
  • Can biomarker expression be used as an indicator of response to preoperative chemotherapy in patients with breast cancer?
    Rodriguez-Burford C, Chhieng DC, Jones JL, Meleth S, Grizzle WE, Ferguson SM, 2005 American Association for Cancer Research Meeting, Anaheim, CA
  • Clusterin and Survivin in normal islets and islet cell tumors of pancreas.
    Jhala DN, Jhala NC, Jones J, Grizzle WE, 2005 American Association for Cancer Research Meeting, Anaheim, CA
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Lectures

  • Quality Control of Special Stains: Involvement of External Organizations - Biological Stain Commission and College of American Pathologists. 
    Florida Society for Histotechnology, Regional Meeting
  • Factors Affecting Immunostaining from Fixation to Antigen Retrieval. 
    2nd Annual Advanced Immunohistochemistry Seminar, Birmingham, AL
  • It's All in the Silver Family. 
    Alabama Society for Histotechnology, Regional Meeting, Mobile, AL
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Other

  • Report of the Public Responsibility in Medicine and Research. 
    et al Grizzle WE, et al, The PRIM&R Human Tissue/Specimen Banking Working Group
  • Section II Tools for Investigators, IRBs and Repository Managers. 
    et al, Grizzle WE, et al, The PRIM&R Tissue Working Group Report, Section II
  • Fixation: Impact of Histopathology from Hematoxylin and Eosin Stains to Immunostaining (Part I). 
    Fredenburgh J and Grizzle WE, American Society of Clinical Pathologists Teleconference - Continuing Education
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Press Mentions

  • Closing the Gap
    Closing the GapNovember 3rd, 2022
  • Biobank: What's in a Name?
    Biobank: What's in a Name?June 12th, 2019
  • Grizzle Recognized by ISBER with 2019 Founder’s Award
    Grizzle Recognized by ISBER with 2019 Founder’s AwardMay 1st, 2019
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Grant Support

  • Cooperative Human Tissue NetworkNational Cancer Institute1987–2012
  • Tissue Resource And Molecular Pathology CoreNational Cancer Institute2010–2011
  • Tissue Resources And Molecular Pathology CoreNational Institute Of Arthritis And Musculoskeletal And Skin Diseases2009–2011
  • Tissue Resources/Immunopathology/Molecular AssaysNational Cancer Institute2007–2011
  • Biomarker Reference Laboratory, EdrnNational Cancer Institute2005–2010
  • Tissue Resource/Molecular Analysis/ImmunopathologyNational Institute Of Arthritis And Musculoskeletal And Skin Diseases2007–2008
  • Core--Tissue Resource/Molecular Analysis/ImmunopathologyNational Institute Of Arthritis And Musculoskeletal And Skin Diseases2004–2006
  • Biomarker Validation LaboratoriesNational Cancer Institute2000–2004
  • Core--Tissue Resource And ImmunopathologyNational Cancer Institute2003
  • Confocal DNA Cytometry Prostate Cancer- Age &EthnicityNational Institute On Aging2002–2003
  • Core--Tissue Resource And ImmunopathologyNational Cancer Institute2000–2002
  • Core--Tissue Resources And ImmunopathologyNational Cancer Institute1999–2002
  • Core--Tissue ProcurementNational Cancer Institute1996–2002
  • Risk Biomarker Evaluation--Prostate Cancer ChemopreventDivision Of Cancer Prevention And Control1998–2001
  • Role Of Nutritional And Other Factors In Etiology Of Oral CancerNational Institute Of Dental &Craniofacial Research1996–2001
  • Early Detection Research Network--Tissue CollectionDivision Of Cancer Prevention And Control1994–1995
  • Early Detection Research Network - Tissue CollectionDivision Of Cancer Prevention And Control1991–1993
  • Early Detection Research Network -Division Of Cancer Prevention And Control1992
  • Core Facility--Tissue ProcurementNational Cancer Institute1985

Hospital Affiliations

Dr. William Grizzle, Dr. William Grizzle, MD, Dr. W Grizzle, Dr. William E Grizzle