WilliamRayfordGwinIIIMD

PubMed

• 27 citations
  Combination of ultrasound-based mechanical disruption of tumor with immune checkpoint blockade modifies tumor microenvironment and augments systemic antitumor immunity.
  Shinya Abe, Hiroshi Nagata, Erika J Crosby, Yoshiyuki Inoue, Kensuke Kaneko, Cong-Xiao Liu, Xiao Yang, Tao Wang, Chaitanya R Acharya, Pankaj Agarwal, Joshua Snyder, Wi...> ;Journal for Immunotherapy of Cancer. 2022 Jan 1
• 9 citations
  Pembrolizumab with low-dose carboplatin for recurrent platinum-resistant ovarian, fallopian tube, and primary peritoneal cancer: survival and immune correlates
  John B. Liao, William R. Gwin, Renata R. Urban, Katie M. Hitchcock-Bernhardt, Andrew L. Coveler, Doreen Higgins, Jennifer Childs, Hania Shakalia, Ron E. Swensen, Sasha...> ;Journal for Immunotherapy of Cancer. 2021 Sep 1
• 79 citations
  Vaccine Therapies for Cancer: Then and Now
  Michael A. Morse, William R. Gwin, Duane Mitchell> ;Targeted Oncology. 2021 Jan 29
• 24 citations
  Long-term survival of patients with stage III colon cancer treated with VRP-CEA(6D), an alphavirus vector that increases the CD8+ effector memory T cell to Treg ratio.
  Erika J. Crosby, Amy Hobeika, Donna Niedzwiecki, Christel Rushing, David S. Hsu, Peter Berglund, Jonathan M. Smith, Takuya Osada, William R. Gwin, Zachary C. Hartman, ...> ;Journal for Immunotherapy of Cancer. 2020 Nov 1
• 8 citations
  Heat shock protein 90-targeted photodynamic therapy enables treatment of subcutaneous and visceral tumors.
  Kensuke Kaneko, Takuya Osada, Michael A. Morse, William R. Gwin, Joshua D. Ginzel, Joshua C. Snyder, Xiao Yi Yang, Cong-Xiao Liu, Marcio A. Diniz, Khaldon Bodoor, Phil...> ;Communications Biology. 2020 May 8
• 40 citations
  Vaccine-induced memory CD8+ T cells provide clinical benefit in HER2 expressing breast cancer: a mouse to human translational study.
  Erika J. Crosby, William R. Gwin, Kimberly L. Blackwell, Paul K. Marcom, Serena Chang, Holden T. Maecker, Gloria Broadwater, Terry Hyslop, Sungjin Kim, Andre Rogatko, ...> ;Clinical Cancer Research. 2019 May 1
• 2 citations
  Immuno-Oncology in the Era of Personalized Medicine.
  William R. Gwin, Mary L. Disis, Erika Ruiz-Garcia> ;Advances in Experimental Medicine and Biology. 2019 Jan 1
• 10 citations
  Polyfunctional anti-human epidermal growth factor receptor 3 (anti-HER3) antibodies induced by HER3 vaccines have multiple mechanisms of antitumor activity against the...
  Takuya Osada, Zachary C. Hartman, Junping Wei, Gangjun Lei, Amy Hobeika, William R. Gwin, Marcio A. Diniz, Neil L. Spector, Timothy M. Clay, Wei Chen, Michael A. Morse...> ;Breast Cancer Research. 2018 Aug 9
• 7 citations
  CYP1A1 genetic polymorphism is a promising predictor to improve chemotherapy effects in patients with metastatic breast cancer treated with docetaxel plus thiotepa vs....
  Xinna Zhou, Guoliang Qiao, Xiaoli Wang, Qingkun Song, Michael A. Morse, Amy Hobeika, William R. Gwin, Jun Ren, H. Kim Lyerly> ;Cancer Chemotherapy and Pharmacology. 2018 Feb 1
• 12 citations
  In Vivo Detection of HSP90 Identifies Breast Cancers with Aggressive Behavior
  Takuya Osada, Kensuke Kaneko, William R. Gwin, Michael A. Morse, Amy Hobeika, Brian W. Pogue, Zachary C. Hartman, Philip F. Hughes, Timothy A.J. Haystead, H. Kim Lyerly> ;Clinical Cancer Research. 2017 Dec 15
• 54 citations
  Dendritic Cell/Cytokine-Induced Killer Cell Immunotherapy Combined with S-1 in Patients with Advanced Pancreatic Cancer: A Prospective Study.
  Ni Jiang, Guoliang Qiao, Xiaoli Wang, Michael A. Morse, William R. Gwin, Lei Zhou, Yuguang Song, Yanjie Zhao, Feng Chen, Xinna Zhou, Lefu Huang, Amy Hobeika, Xin Yi, X...> ;Clinical Cancer Research. 2017 Sep 1
• 16 citations
  Vaccination targeting human HER3 alters the phenotype of infiltrating T cells and responses to immune checkpoint inhibition
  Takuya Osada, Michael A. Morse, Amy Hobeika, Marcio A. Diniz, William R. Gwin, Zachary C. Hartman, Junping Wei, Hongtao Guo, Xiao Yi Yang, Cong-Xiao Liu, Kensuke Kanek...> ;Oncoimmunology. 2017 Apr 12
• 22 citations
  Adaptive T cell responses induced by oncolytic Herpes Simplex Virus-granulocyte macrophage-colony-stimulating factor therapy expanded by dendritic cell and cytokine-in...
  Jun Ren, William R. Gwin, Xinna Zhou, Xiaoli Wang, Hongyan Huang, Ni Jiang, Lei Zhou, Pankaj K. Agarwal, Amy Hobeika, Erika J. Crosby, Zachary C. Hartman, Michael A. M...> ;Oncoimmunology. 2017 Apr 5
• 46 citations
  A signature of epithelial-mesenchymal plasticity and stromal activation in primary tumor modulates late recurrence in breast cancer independent of disease subtype
  Qing Cheng, Jeffrey T. Chang, William R. Gwin, Jun Zhu, Stefan Ambs, Joseph Geradts, H. Kim Lyerly> ;Breast Cancer Research. 2014 Jul 25
• 11 citations
  Pertuzumab protects the Achilles' heel of trastuzumab-emtansine
  William R. Gwin, Neil L. Spector> ;Clinical Cancer Research. 2014 Jan 15
• 110 citations
  An heregulin-EGFR-HER3 autocrine signaling axis can mediate acquired lapatinib resistance in HER2+ breast cancer models
  Wenle Xia, Emanual Petricoin, Sumin Zhao, Leihua Liu, Takuya Osada, Qing Cheng, Julia Wulfkuhle, William R. Gwin, Xiao Yi Yang, Rosa I. Gallagher, Sarah S. Bacus, H. K...> ;Breast Cancer Research. 2013 Sep 18
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Lectures

• Phase II study of neoadjuvant IGFBP-2 vaccination with neoadjuvant carboplatin and paclitaxel in advanced ovarian cancer. 
  2018 ASCO Annual Meeting - Chicago, Illinois - 06/4/2018