WilliamFranklinHoffmanMD

Psychiatry • Portland, OR

Geriatric Psychiatry

Associate Professor, Psychiatry, Oregon Health and Science University School of Medicine

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Office
3710 Sw Us Veterans Hospital Rd
Mental Health Division P35c
Portland, OR 97239
Phone+1 503-273-5049
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Summary

Dr. William Hoffman, MD is a board certified psychiatrist in Portland, Oregon. He is currently licensed to practice medicine in Oregon. He is affiliated with Portland HCS and OHSU Hospital.

Education & Training

Oregon Health & Science UniversityResidency, Psychiatry, 1981 - 1985
University of Wisconsin School of Medicine & Public HealthClass of 1981

Certifications & Licensure

OR State Medical License 1982 - 2025
American Board of Psychiatry and Neurology Psychiatry

Clinical Trials

Neurobiology of Alcohol and Nicotine Co-Addiction Start of enrollment: 2017 Oct 01
Completed
Pilot Study of the Effect of Ibudilast on Neuroinflammation in Methamphetamine Users Start of enrollment: 2019 May 01
Recruiting
Phase 2

Publications & Presentations

PubMed

4 citations
Cognition during active methamphetamine use versus remission
Marilyn Huckans, Stephen J. Boyd, Grant Moncrief, Nathan Hantke, Bethany Winters, Kate Shirley, Emily Sano, Holly McCready, Laura E. Dennis, Milky Kohno, William F. Ho...> ;Journal of Clinical and Experimental Neuropsychology. 2021 Oct 6
7 citations
Dopamine dysfunction in stimulant use disorders: mechanistic comparisons and implications for treatment.
Milky Kohno, Laura E. Dennis, Holly D. McCready, William F. Hoffman> ;Molecular Psychiatry. 2021 Jun 11
3 citations
Intranasal Oxytocin for Stimulant Use Disorder Among Male Veterans Enrolled in an Opioid Treatment Program: A Randomized Controlled Trial.
Christopher S Stauffer, Salem Samson, Alex Hickok, William F Hoffman, Steven L Batki> ;Frontiers in Psychiatry. 2021 Jan 1
5 citations
Psychopathy and Corticostriatal Connectivity: The Link to Criminal Behavior in Methamphetamine Dependence.
William F. Hoffman, Merel B. Jacobs, Laura E. Dennis, Holly D. McCready, Alex W. Hickok, Sheehan B. Smith, Milky Kohno> ;Frontiers in Psychiatry. 2020 Feb 28
2 citations
Correction to: Neural correlates of reward magnitude and delay during a probabilistic delay discounting task in alcohol use disorder.
Laura E. Dennis, Milky Kohno, Holly D. McCready, Daniel Schwartz, Britta Schwartz, David Lahna, Bonnie J. Nagel, Suzanne H. Mitchell, William F. Hoffman> ;Psychopharmacology. 2020 Jan 1
15 citations
Neural correlates of reward magnitude and delay during a probabilistic delay discounting task in alcohol use disorder.
Laura E. Dennis, Milky Kohno, Holly D. McCready, Daniel Schwartz, Britta Schwartz, David Lahna, Bonnie J. Nagel, Suzanne H. Mitchell, William F. Hoffman> ;Psychopharmacology. 2020 Jan 1
12 citations
Trace amine-associated receptor gene polymorphism increases drug craving in individuals with methamphetamine dependence.
Jennifer M. Loftis, Michael R. Lasarev, Xiao Shi, Jodi Lapidus, Aaron Janowsky, William F. Hoffman, Marilyn Huckans> ;Plos One. 2019 Oct 10
9 citations
Effects of Naltrexone on Large-Scale Network Interactions in Methamphetamine Use Disorder.
Milky Kohno, Angelical M Morales, Laura E. Dennis, Holly D. McCready, William F. Hoffman, P. Todd Korthuis> ;Frontiers in Psychiatry. 2019 Sep 3
92 citations
Neuroinflammation in addiction: A review of neuroimaging studies and potential immunotherapies.
Milky Kohno, Jeanne M. Link, Laura E. Dennis, Holly McCready, Marilyn Huckans, William F. Hoffman, Jennifer M. Loftis> ;Pharmacology, Biochemistry, and Behavior. 2019 Jan 26
2 citations
Functional MRI and delay discounting in patients infected with hepatitis C.
Holly McCready, Milky Kohno, Michael Kolessar, Laura E. Dennis, Daniel Kriz, Hannah S. Luber, Renee Anderson, Michael Chang, Anna Sasaki, Kenneth D. Flora, Arthur A. V...> ;Journal of Neurovirology. 2018 Oct 8
21 citations
A preliminary randomized clinical trial of naltrexone reduces striatal resting state functional connectivity in people with methamphetamine use disorder.
Milky Kohno, Laura E. Dennis, Holly McCready, Daniel Schwartz, William F. Hoffman, P. Todd Korthuis> ;Drug and Alcohol Dependence. 2018 Nov 1
20 citations
The relationship between interleukin-6 and functional connectivity in methamphetamine users.
Milky Kohno, Jennifer M. Loftis, Marilyn Huckans, Laura E. Dennis, Holly McCready, William F. Hoffman> ;Neuroscience Letters. 2018 Jun 11
34 citations
Executive Control and Striatal Resting-State Network Interact with Risk Factors to Influence Treatment Outcomes in Alcohol-Use Disorder.
Milky Kohno, Laura E. Dennis, Holly McCready, William F. Hoffman> ;Frontiers in Psychiatry. 2017 Sep 25
15 citations
Everyday problems with executive dysfunction and impulsivity in adults recovering from methamphetamine addiction
Carilyn C. Ellis, William F. Hoffman, Sarah Jaehnert, Jane M. Plagge, Jennifer M. Loftis, Daniel Schwartz, Marilyn Huckans> ;Addictive Disorders & Their Treatment. 2016 Mar 1
96 citations
Methamphetamine Causes Persistent Immune Dysregulation: A Cross-Species, Translational Report
Jennifer M. Loftis, Dongseok Choi, William F. Hoffman, Marilyn Huckans> ;Neurotoxicity Research. 2011 Jul 1
29 citations
Discounting of delayed rewards and executive dysfunction in individuals infected with hepatitis C
Marilyn Huckans, Adriana Seelye, Jonathan Woodhouse, Tiffany Parcel, Lisa Mull, Daniel Schwartz, Alex Mitchell, David Lahna, Amy L. Johnson, Jennifer M. Loftis, Steven...> ;Journal of Clinical and Experimental Neuropsychology. 2011 Feb 1
26 citations
Niacin sensitivity and the arachidonic acid pathway in schizophrenia
Erik Messamore, William F. Hoffman, Jeffrey K. Yao> ;Schizophrenia Research. 2010 Sep 1
126 citations
Global and local morphometric differences in recently abstinent methamphetamine-dependent individuals.
Daniel Schwartz, Alex Mitchell, David Lahna, Hannah S. Luber, Marilyn Huckans, Suzanne H. Mitchell, William F. Hoffman> ;Neuroimage. 2010 May 1
149 citations
Cortical activation during delay discounting in abstinent methamphetamine dependent individuals
William F. Hoffman, Daniel Schwartz, Marilyn Huckans, Bentson H. McFarland, Gal Meiri, Alexander A. Stevens, Suzanne H. Mitchell> ;Psychopharmacology. 2008 Aug 7
6 citations
Clinical Outcomes of Integrated Psychiatric and General Medical Care
Kristen Snyder, Steven K. Dobscha, Linda Ganzini, William F. Hoffman, Molly A. Delorit> ;Community Mental Health Journal. 2008 Jun 1
198 citations
Neuropsychological function and delay discounting in methamphetamine-dependent individuals.
William F. Hoffman, Meredith Moore, Raymond Templin, Bentson H. McFarland, Robert Hitzemann, Suzanne H. Mitchell> ;Psychopharmacology. 2006 Aug 17
58 citations
The niacin skin flush abnormality in schizophrenia: a quantitative dose-response study.
Erik Messamore, William F. Hoffman, Aaron Janowsky> ;Schizophrenia Research. 2003 Aug 1
11 citations
Strategies to decrease costs of prescribing selective serotonin reuptake inhibitors at a VA Medical Center.
Steven K. Dobscha, Thomas A. Anderson, William F. Hoffman, Lisa M. Winterbottom, Erick H. Turner, Leann S. Snodgrass, Peter Hauser> ;Psychiatric Services. 2003 Feb 1
21 citations
Quality of life in treated and never‐treated schizophrenic patients
Carla A. Green, Darien S. Fenn, Driss Moussaoui, Nadia Kadri, William F. Hoffman> ;Acta Psychiatrica Scandinavica. 2001 Feb 1
167 citations
Correlates of suffering in amyotrophic lateral sclerosis
Linda Ganzini, Wendy Johnston, William F. Hoffman> ;Neurology. 1999 Apr 1
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Press Mentions

MediciNova Announces Collaboration with the U.S. Department of Veterans Affairs and Oregon Health & Science University to Evaluate MN-166 (Ibudilast) in Methamphetamine Use DisorderNovember 9th, 2017
Depression Treatment Center OregonNovember 1st, 2017

Hospital Affiliations

Portland HCSPortland, Oregon
OHSU HospitalPortland, Oregon