WilliamRHolmesDO

PubMed

• Biophysical attributes that affect CaMKII activation deduced with a novel spatial stochastic simulation approach.
  Li, X.,Holmes, W. R.> ;PLoS Comput. Biol.. 2018 Feb 06
• 39 citations
  Mechanochemical feedback underlies coexistence of qualitatively distinct cell polarity patterns within diverse cell populations
  JinSeok Park, William R. Holmes, Sung Hoon Lee, Hong Nam Kim, Deok Ho Kim, Moon Kyu Kwak, Chiaochun Joanne Wang, Leah Edelstein-Keshet, Andre Levchenko> ;Proceedings of the National Academy of Sciences of the United States of America. 2017 Jul 11
• Correction: Understanding metal homeostasis in primary cultured neurons. Studies using single neuron subcellular and quantitative metallomics.
  Colvin RA, Lai B, Holmes WR, Lee D> ;Metallomics. 2015-09-01
• Minimizing the caliber of myelinated axons by means of nodal constrictions.
  Johnson C, Holmes WR, Brown A, Jung P> ;J. Neurophysiol.. 2015-09-01
• Understanding metal homeostasis in primary cultured neurons. Studies using single neuron subcellular and quantitative metallomics.
  Colvin RA, Lai B, Holmes WR, Lee D> ;Metallomics. 2015-07-01
• Local perturbation analysis: a computational tool for biophysical reaction-diffusion models.
  Holmes WR, Mata MA, Edelstein-Keshet L> ;Biophys. J.. 2015-01-20
• 3 citations
  Interactions and tradeoffs between cell recruitment, proliferation, and differentiation affect CNS regeneration.
  William R. Holmes, Qing Nie> ;Biophysical Journal. 2014 Apr 1
• An excitable compass guides chemotaxis?
  Holmes WR> ;Biophys. J.. 2014-03-04
• Decreased afferent excitability contributes to synaptic depression during high-frequency stimulation in hippocampal area CA1.
  Kim E, Owen B, Holmes WR, Grover LM> ;J. Neurophysiol.. 2012-10-01
• The effect of noise on CaMKII activation in a dendritic spine during LTP induction.
  Zeng, S., Holmes, W.R.> ;J Neurophysiol. 2010 Apr
• LTP in hippocampal area CA1 is induced by burst stimulation over a broad frequency range centered around delta.
  Grover, L.M., Kim, E., Cooke, J.D., Holmes, W.R.> ;Learn Mem. 2009-01-01
• A classification method to distinguish cell-specific responses elicited by current pulses in hippocampal CA1 pyramidal cells.
  Ambros-Ingerson, J., Grover, L.M., Holmes, W.R.> ;Neural Comput. 2008 Jun
• Insights into Zn2+ homeostasis in neurons from experimental and modeling studies.
  Colvin, R.A., Bush, A.I., Volitakis, I., Fontaine, C.P., Thomas, D., Kikuchi, K., Holmes, W.R.> ;Am J Physiol Cell Physiol. 2008 Mar
• Quantifying the magnitude of changes in synaptic level parameters with long-term potentiation.
  Holmes, W.R., Grover, L.M.> ;J Neurophysiol. 2006 Sep
• Analysis and comparison of morphological reconstructions of hippocampal field CA1 pyramidal cells.
  Ambros-Ingerson, J.,Holmes, W. R.> ;Hippocampus. 2005
• An aminopyridine-sensitive, early outward current recorded in vivo in neurons of the precruciate cortex of cats using single-electrode voltage-clamp techniques.
  Woody CD, Baranyi A, Szente MB, Gruen E, Holmes W, Nenov V, Strecker GJ> ;Brain Res.. 1989-02-20
• A continuous cable method for determining the transient potential in passive dendritic trees of known geometry.
  Holmes, W. R.> ;Biol Cybern. 1986 Jan 01
• Is the function of dendritic spines to concentrate calcium?
  Holmes, W. R.> ;Brain Res. 1990 Jun 11
• Matching dendritic neuron models to experimental data.
  Rall, W., Burke, R. E., Holmes, W. R., Jack, J. J., Redman, S. J., Segev, I.> ;Physiol Rev. 1992 Oct
• Effects of uniform and non-uniform synaptic ''activation-distributions'' on the cable properties of modeled cortical pyramidal neurons.
  Holmes, W. R., Woody, C. D.> ;Brain Res. 1989 Dec 25
• The role of dendritic diameters in maximizing the effectiveness of synaptic inputs.
  Holmes, W. R.> ;Brain Res. 1989 Jan 23
• Electrotonic length estimates in neurons with dendritic tapering or somatic shunt.
  Holmes, W. R., Rall, W.> ;J Neurophysiol. 1992 Oct
• Interpretation of time constant and electrotonic length estimates in multicylinder or branched neuronal structures.
  Holmes, W. R., Segev, I., Rall, W.> ;J Neurophysiol. 1992 Oct
• Role of multiple calcium and calcium-dependent conductances in regulation of hippocampal dentate granule cell excitability.
  Aradi, I., Holmes, W. R.> ;J Comput Neurosci. 1999 May 01
• Estimating the electrotonic structure of neurons with compartmental models.
  Holmes, W. R., Rall, W.> ;J Neurophysiol. 1992 Oct
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