WilliamJJanssenMD

PubMed

• Interstitial Macrophages Mediate Efferocytosis of Alveolar Epithelium during Influenza Infection.
  Marilia Sanchez Santos Rizzo Zuttion, Tanyalak Parimon, Changfu Yao, Barry R Stripp, Ying Wang, Christopher M Soto, Zackary Ortega, Xiao Li, William J Janssen, Peter Chen> ;American Journal of Respiratory Cell and Molecular Biology. 2024 Mar 1
• Thiol-Michael Addition Microparticles: Their Synthesis, Characterization, and Uptake by Macrophages.
  Emerson L Grey, Jazalle McClendon, Joshita Suresh, Scott Alper, William J Janssen, Stephanie J Bryant> ;ACS Biomaterials Science & Engineering. 2023 Jul 10
• 4 citations
  Marked elevations in lung and plasma ceramide in COVID-19 linked to microvascular injury.
  Irina Petrache, Elisabet Pujadas, Aditya Ganju, Karina A Serban, Alexander Borowiec, Beatrice Babbs, Irina A Bronova, Nicholas Egersdorf, Patrick S Hume, Khushboo Goel...> ;JCI Insight. 2023 May 22
• Cigarette smoke-induced airspace disease in mice develops independently of HIF-1α signaling in leukocytes.
  Patrick S Hume, Jazalle McClendon, Katrina W Kopf, Julie W Harral, Joanna M Poczobutt, Alexandra L McCubbrey, Bradford J Smith, Peter M Henson, Susan M Majka, Irina Pe...> ;American Journal of Physiology. Lung Cellular and Molecular Physiology. 2022 Oct 1
• 10 citations
  SARS-CoV-2 infection relaxes peripheral B cell tolerance.
  Moriah J Castleman, Megan M Stumpf, Nicholas R Therrien, Mia J Smith, Kelsey E Lesteberg, Brent E Palmer, James P Maloney, William J Janssen, Kara J Mould, J David Bec...> ;The Journal of Experimental Medicine. 2022 Jun 6
• 10 citations
  Single-cell RNA sequencing identifies G-protein coupled receptor 87 as a basal cell marker expressed in distal honeycomb cysts in idiopathic pulmonary fibrosis.
  Katharina Heinzelmann, Qianjiang Hu, Yan Hu, Evgenia Dobrinskikh, Meshal Ansari, M Camila Melo-Narváez, Henrik M Ulke, Colton Leavitt, Carol Mirita, Tammy Trudeau, Max...> ;The European Respiratory Journal. 2022 Jun 1
• 6 citations
  Mapping Macrophage Polarization and Origin during the Progression of the Foreign Body Response to a Poly(ethylene glycol) Hydrogel Implant.
  Leila S Saleh, Luke D Amer, Brittany J Thompson, Thomas Danhorn, Jennifer R Knapp, Sophie L Gibbings, Stacey Thomas, Lea Barthel, Brian P O'Connor, William J Janssen, ...> ;Advanced Healthcare Materials. 2022 May 1
• 11 citations
  Excess neuropeptides in lung signal through endothelial cells to impair gas exchange.
  Jinhao Xu, Le Xu, Pengfei Sui, Jiyuan Chen, Esteban A Moya, Patrick Hume, William J Janssen, Jason M Duran, Patricia Thistlethwaite, Aaron Carlin, Peter Gulleman, Bran...> ;Developmental Cell. 2022 Apr 11
• 11 citations
  Increased histone-DNA complexes and endothelial-dependent thrombin generation in severe COVID-19.
  Beth A Bouchard, Christos Colovos, Michael A Lawson, Zachary T Osborn, Adrian M Sackheim, Kara J Mould, William J Janssen, Mitchell J Cohen, Devdoot Majumdar, Kalev Fr...> ;Vascular Pharmacology. 2022 Feb 1
• 30 citations
  Polyamine import and accumulation causes immunomodulation in macrophages engulfing apoptotic cells.
  Alexandra L McCubbrey, Shannon A McManus, Jazalle D McClendon, Stacey M Thomas, Hope B Chatwin, Julie A Reisz, Angelo D'Alessandro, Kara J Mould, Donna L Bratton, Pete...> ;Cell Reports. 2022 Jan 11
• 12 citations
  Autoantibodies elicited with SARS-CoV-2 infection are linked to alterations in double negative B cells.
  Moriah J Castleman, Megan M Stumpf, Nicholas R Therrien, Mia J Smith, Kelsey E Lesteberg, Brent E Palmer, James P Maloney, William J Janssen, Kara J Mould, J David Bec...> ;Frontiers in Immunology. 2022 Jan 1
• 1 citations
  Isolation and Analysis of Macrophage Subsets from the Mouse and Human Lung.
  Emily M King, Patrick S Hume, William J Janssen, Alexandra L McCubbrey> ;Methods in Molecular Biology. 2022 Jan 1
• 18 citations
  Sputum Neutrophil Extracellular Trap Subsets Associate with IgA Anti-Citrullinated Protein Antibodies in Subjects At-Risk for Rheumatoid Arthritis
  Yuko Okamoto, Stephanie Devoe, Nickie L Seto, Valerie Minarchick, Timothy M. Wilson, Heather M. Rothfuss, Michael P. Mohning, Jaron Arbet, Miranda E. Kroehl, Ashley Vi...> ;Arthritis & Rheumatology. 2021 Aug 9
• 1 citations
  Signs of self-sustained inflammatory circuits in severe COVID pneumonia.
  Kara J. Mould, William J. Janssen> ;Nature. 2021 Feb 8
• Air-Inflation of Murine Lungs with Vascular Perfusion-Fixation.
  Stacey M. Thomas, Joseph M. Bednarek, William J. Janssen, Patrick S. Hume> ;Journal of Visualized Experiments. 2021 Feb 2
• 18 citations
  Disulfide disruption reverses mucus dysfunction in allergic airway disease.
  Leslie E. Morgan, Ana M. Jaramillo, Siddharth K. Shenoy, Dorota S Raclawska, Nkechinyere A. Emezienna, Vanessa L. Richardson, Naoko Hara, Anna Q. Harder, James C. NeeD...> ;Nature Communications. 2021 Jan 11
• 32 citations
  Human and Mouse Transcriptome Profiling Identifies Cross-Species Homology in Pulmonary and Lymph Node Mononuclear Phagocytes.
  Sonia M. Leach, Sophie L. Gibbings, Anita Tewari, Shaikh M. Atif, Brian Vestal, Thomas Danhorn, William J. Janssen, Tor D. Wager, Claudia Jakubzick> ;Cell Reports. 2020 Nov 3
• 49 citations
  Airspace Macrophages and Monocytes Exist in Transcriptionally Distinct Subsets in Healthy Adults.
  Kara J. Mould, Camille M. Moore, Shannon A McManus, Alexandra L. McCubbrey, Jazalle McClendon, Christine L Griesmer, Peter M. Henson, William J. Janssen> ;American Journal of Respiratory and Critical Care Medicine. 2021 Apr 15
• 31 citations
  Interstitial macrophage-derived thrombospondin-1 contributes to hypoxia-induced pulmonary hypertension
  Rajesh Kumar, Claudia Mickael, Biruk Kassa, Linda Sanders, Daniel Hernandez-Saavedra, Daniel E. Koyanagi, Sushil Kumar, Steve C Pugliese, Stacey M. Thomas, Jazalle McC...> ;Cardiovascular Research. 2020 Oct 1
• 17 citations
  LIM-Nebulette Reinforces Podocyte Structural Integrity by Linking Actin and Vimentin Filaments.
  Xuhua Ge, Tao Zhang, Xiaoxia Yu, Alecia N. Muwonge, Nanditha Anandakrishnan, Nicholas J. Wong, Jonathan C Haydak, Jordan M Reid, Jia Fu, Jenny Wong, Smiti Bhattacharya...> ;Journal of the American Society of Nephrology. 2020 Jul 31
• 29 citations
  The diabetic microenvironment causes mitochondrial oxidative stress in glomerular endothelial cells and pathological crosstalk with podocytes.
  Gabriella Casalena, Liping Yu, Roberto Gil, Samuel Rodriguez, Shantel Sosa, William J. Janssen, Evren U. Azeloglu, Jeremy S. Leventhal, Ilse Daehn> ;Cell Communication and Signaling. 2020 Jul 8
• 40 citations
  Cholesterol 25-hydroxylase promotes efferocytosis and resolution of lung inflammation
  Jennifer H. Madenspacher, Eric D. Morrell, Kymberly M Gowdy, Jeffrey G. McDonald, Bonne M. Thompson, Ginger W. Muse, Jennifer Martinez, Seddon Y. Thomas, Carmen Mikace...> ;JCI Insight. 2020 Jun 4
• 37 citations
  Localization of Macrophages in the Human Lung via Design-based Stereology.
  Patrick S. Hume, Sophie L. Gibbings, Claudia Jakubzick, Rubin M. Tuder, Douglas Curran-Everett, Peter M. Henson, Bradford J. Smith, William J. Janssen> ;American Journal of Respiratory and Critical Care Medicine. 2020 May 15
• 9 citations
  NF-κB mediates lipopolysaccharide-induced alternative pre-mRNA splicing of MyD88 in mouse macrophages.
  Frank Fang-Yao Lee, Kevin Davidson, Chelsea Harris, Jazalle McClendon, William J. Janssen, Scott Alper> ;The Journal of Biological Chemistry. 2020 May 1
• 12 citations
  Inflammation-Induced Alternative Pre-mRNA Splicing in Mouse Alveolar Macrophages
  William J. Janssen, Thomas Danhorn, Chelsea Harris, Kara J. Mould, Frank Fang-Yao Lee, Brenna R. Hedin, Angelo D'Alessandro, Sonia M. Leach, Scott Alper> ;G3. 2020 Feb 1
• Join now to see all

Journal Articles

• TGF-Β Activation by Bone Marrow-Derived Thrombospondin-1 Causes Schistosoma- and Hypoxia-Induced Pulmonary Hypertension  
  William J Janssen, Jeffrey C Robinson, Rubin M Tuder, Kurt R Stenmark, Nature