WilliamJohnSnapeJr.MD

Gastroenterology • San Francisco, CA

Esophagus Disease

Professor, Medicine, UCLA School of Medicine

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Office
2340 Clay St
2nd Floor
San Francisco, CA 94115
Phone+1 415-600-1138

Fax+1 415-600-1122
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Education & Training

University of Pennsylvania Health SystemFellowship, Gastroenterology, 1974 - 1975
University of Pennsylvania Health SystemResidency, Internal Medicine, 1973 - 1974
Jacobi Medical Center/Albert Einstein College of MedicineResidency, Internal Medicine, 1969 - 1971
Sidney Kimmel Medical College at Thomas Jefferson UniversityClass of 1969

Certifications & Licensure

CA State Medical License 1981 - 2025
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Gastroenterology

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2012-2013
Fellow (AGAF) American Gastroenterological Association, 2006
Elected Member The American Society for Clinical Investigation, 1983
Fellow (FACG) American College of Gastroenterology
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Clinical Trials

Nortriptyline for Idiopathic Gastroparesis Start of enrollment: 2009 Jan 01
Completed
Phase 3
Continuous Glucose Monitoring and Insulin Pump Therapy in Diabetic Gastroparesis Start of enrollment: 2011 May 01
Completed
Not Applicable
Aprepitant for the Relief of Nausea in Patients With Chronic Nausea and Vomiting of Presumed Gastric Origin Trial Start of enrollment: 2013 Apr 01
Completed
Phase 2
Gastroparesis Registry 2 Start of enrollment: 2012 Jul 01
Completed
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Publications & Presentations

PubMed

100 citations
Functional Dyspepsia and Gastroparesis in Tertiary Care are Interchangeable Syndromes With Common Clinical and Pathologic Features.
P. J. Pasricha, Madhusudan Grover, Katherine P. Yates, Thomas L. Abell, Cheryl E. Bernard, Kenneth L. Koch, Richard W. McCallum, Irene Sarosiek, Braden Kuo, Robert S. ...> ;Gastroenterology. 2021 May 1
11 citations
Marijuana Use in Patients with Symptoms of Gastroparesis: Prevalence, Patient Characteristics, and Perceived Benefit
Henry P. Parkman, Emily P. Sharkey, Linda Nguyen, Katherine P. Yates, Thomas L. Abell, William L. Hasler, William J. Snape, John Clarke, Ron Schey, Kenneth L. Koch, Br...> ;Digestive Diseases and Sciences. 2020 Aug 1
27 citations
Autonomic function in gastroparesis and chronic unexplained nausea and vomiting: Relationship with etiology, gastric emptying, and symptom severity.
Linda Nguyen, Laura A. Wilson, Laura Miriel, Pankaj J. Pasricha, Braden Kuo, William L. Hasler, Richard W. McCallum, Irene Sarosiek, Kenneth L. Koch, William J. Snape,...> ;Neurogastroenterology and Motility. 2020 Feb 15
5 citations
Satiety testing in diabetic gastroparesis: Effects of insulin pump therapy with continuous glucose monitoring on upper gastrointestinal symptoms and gastric myoelectri...
Kenneth L. Koch, William L. Hasler, Mark L. Van Natta, Jorge Calles-Escandon, Madhusudan Grover, P. J. Pasricha, William J. Snape, Henry P. Parkman, Thomas L. Abell, R...> ;Neurogastroenterology and Motility. 2020 Jan 1
23 citations
Delayed gastric emptying associates with diabetic complications in diabetic patients with symptoms of gastroparesis
Henry P. Parkman, Laura A. Wilson, Gianrico Farrugia, Kenneth L. Koch, William L. Hasler, Linda Nguyen, Thomas L. Abell, William J. Snape, John O. Clarke, Braden Kuo, ...> ;The American Journal of Gastroenterology. 2019 Nov 1
RESPONSE TO LETTER TO EDITOR BY PANNEMANS ET AL.
William L. Hasler, Laura Wilson, Linda Nguyen, William J. Snape, Thomas L. Abell, Kenneth L. Koch, Richard W. McCallum, Pankaj J. Pasricha, Irene Sarosiek, Gianrico Fa...> ;Clinical Gastroenterology and Hepatology. 2019 Oct 10
28 citations
Effectiveness of gastric electrical stimulation in gastroparesis: Results from a large prospectively collected database of national gastroparesis registries
Thomas L. Abell, Goro Yamada, Richard W McCallum, Mark L. Van Natta, James Tonascia, Henry P. Parkman, Kenneth L. Koch, Irene Sarosiek, Gianrico Farrugia, Madhusudan G...> ;Neurogastroenterology and Motility. 2019 Dec 1
23 citations
Abdominal Pain in Patients with Gastroparesis: Associations with Gastroparesis Symptoms, Etiology of Gastroparesis, Gastric Emptying, Somatization, and Quality of Life
Henry P. Parkman, Laura A. Wilson, William L. Hasler, Richard W McCallum, Irene Sarosiek, Kenneth L. Koch, Thomas L. Abell, Ron Schey, Braden Kuo, William J. Snape, Li...> ;Digestive Diseases and Sciences. 2019 Aug 15
26 citations
Ethnic, Racial, and Sex Differences in Etiology, Symptoms, Treatment, and Symptom Outcomes of Patients With Gastroparesis.
Henry P. Parkman, Goro Yamada, Mark L. Van Natta, Katherine P. Yates, William L. Hasler, Irene Sarosiek, Madhusudan Grover, Ron Schey, Thomas L. Abell, Kenneth L. Koch...> ;Clinical Gastroenterology and Hepatology. 2019 Jul 1
37 citations
Opioid Use and Potency Are Associated With Clinical Features, Quality of Life, and Use of Resources in Patients With Gastroparesis.
William L. Hasler, Laura A. Wilson, Linda A. Nguyen, William J. Snape, Thomas L. Abell, Kenneth L. Koch, Richard W. McCallum, P. J. Pasricha, Irene Sarosiek, Gianrico ...> ;Clinical Gastroenterology and Hepatology. 2019 Jun 1
30 citations
Transcriptomic signatures reveal immune dysregulation in human diabetic and idiopathic gastroparesis
Madhusudan Grover, Simon J. Gibbons, Asha Nair, Cheryl E. Bernard, Adeel S. Zubair, Seth T. Eisenman, Laura A. Wilson, Laura Miriel, Pankaj J. Pasricha, Henry P. Parkm...> ;BMC Medical Genomics. 2018 Aug 7
20 citations
Glucose sensor-augmented continuous subcutaneous insulin infusion in patients with diabetic gastroparesis: An open-label pilot prospective study.
Jorge Calles-Escandon, Kenneth L. Koch, William L. Hasler, Mark L. Van Natta, Pankaj J. Pasricha, James Tonascia, Henry P. Parkman, Frank A. Hamilton, William H. Herma...> ;Plos One. 2018 Apr 13
6 citations
Islet cell associated autoantibodies and C-peptide levels in patients with diabetes and symptoms of gastroparesis
Elias S. Siraj, Carol J. Homko, Laura A. Wilson, Patrick May, Ajay D. Rao, Jorge Calles, Gianrico Farrugia, William L. Hasler, Kenneth L. Koch, Linda Nguyen, William J...> ;Frontiers in Endocrinology. 2018 Feb 13
49 citations
Relating gastric scintigraphy and symptoms to motility capsule transit and pressure findings in suspected gastroparesis.
William L. Hasler, Kevin P. May, Laura A. Wilson, M. L. Van Natta, Henry P. Parkman, P. J. Pasricha, K. L. Koch, Thomas L. Abell, Richard W. McCallum, Linda Anh B. Ngu...> ;Neurogastroenterology and Motility. 2018 Feb 1
14 citations
Repeat polymorphisms in the Homo sapiens heme oxygenase-1 gene in diabetic and idiopathic gastroparesis.
Simon J. Gibbons, Madhusudan Grover, Kyoung Moo Choi, Akhilesh Wadhwa, Adeel S. Zubair, Laura A. Wilson, Yanhong Wu, Thomas L. Abell, William L. Hasler, Kenneth L. Koc...> ;Plos One. 2017 Nov 21
79 citations
Aprepitant Has Mixed Effects on Nausea and Reduces Other Symptoms in Patients With Gastroparesis and Related Disorders
Pankaj J. Pasricha, Katherine P. Yates, Irene Sarosiek, Richard W. McCallum, Thomas L. Abell, Kenneth L. Koch, Linda Anh B. Nguyen, William J. Snape, William L. Hasler...> ;Gastroenterology. 2018 Jan 1
36 citations
Intragastric Meal Distribution During Gastric Emptying Scintigraphy for Assessment of Fundic Accommodation: Correlation with Symptoms of Gastroparesis
Perry Orthey, Daohai Yu, Mark L. Van Natta, Frederick V. Ramsey, Jesus R. Diaz, Paige Bennett, Andrei Iagaru, Roberto A. Salas Fragomeni, Richard W. McCallum, Irene Sa...> ;Journal of Nuclear Medicine. 2018 Apr 1
44 citations
Early satiety and postprandial fullness in gastroparesis correlate with gastroparesis severity, gastric emptying, and water load testing.
Henry P. Parkman, Erin Hallinan, William L. Hasler, Gianrico Farrugia, K. L. Koch, Linda Nguyen, William J. Snape, Thomas L. Abell, Richard W. McCallum, Irene Sarosiek...> ;Neurogastroenterology and Motility. 2017 Apr 1
58 citations
Diabetic and idiopathic gastroparesis is associated with loss of CD206-positive macrophages in the gastric antrum
Madhusudan Grover, Cheryl E. Bernard, P. J. Pasricha, Henry P. Parkman, Simon J. Gibbons, James Tonascia, K. L. Koch, Richard W. McCallum, Irene Sarosiek, William L. H...> ;Neurogastroenterology and Motility. 2017 Jan 9
47 citations
Nausea and vomiting in gastroparesis: similarities and differences in idiopathic and diabetic gastroparesis.
Henry P. Parkman, Erin Hallinan, William L. Hasler, Gianrico Farrugia, K. L. Koch, J. Calles, William J. Snape, Thomas L. Abell, Irene Sarosiek, Richard W. McCallum, L...> ;Neurogastroenterology and Motility. 2016 Dec 1
4 citations
Toward a Better Drug for Gastroparesis: The Problem With a Moving Target
Pankaj J. Pasricha, William J. Snape> ;Gastroenterology. 2016 Jul 1
73 citations
Evaluation of the pylorus with concurrent intraluminal pressure and EndoFLIP in patients with nausea and vomiting.
William J. Snape, M. S. Lin, N. Agarwal, Richard E. Shaw> ;Neurogastroenterology and Motility. 2016 May 1
34 citations
Baseline features and differences in 48 week clinical outcomes in patients with gastroparesis and type 1 vs type 2 diabetes
K. L. Koch, William L. Hasler, Katherine P. Yates, Henry P. Parkman, P. J. Pasricha, Jorge Calles-Escandon, William J. Snape, Thomas L. Abell, Richard W. McCallum, Lin...> ;Neurogastroenterology and Motility. 2016 Mar 6
84 citations
Outcomes and Factors Associated with Reduced Symptoms in Patients with Gastroparesis
Pankaj J. Pasricha, Katherine P. Yates, Linda Nguyen, John O. Clarke, Thomas L. Abell, Gianrico Farrugia, William L. Hasler, Kenneth L. Koch, William J. Snape, Richard...> ;Gastroenterology. 2015 Dec 1
34 citations
Clinical presentation and pathophysiology of gastroparesis.
Linda Anh Nguyen, William J. Snape> ;Gastroenterology Clinics of North America. 2015 Mar 1
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