WilliamNassibWilliamMD

PubMed

• 20 citations
  Cold and heterogeneous T cell repertoire is associated with copy number aberrations and loss of immune genes in small-cell lung cancer
  Ming Chen, Runzhe Chen, Ying Jin, Jun Li, Xin Hu, Jiexin Zhang, Junya Fujimoto, Shawna M Hubert, Bo Zhu, Yanhua Tian, Nicholas McGranahan, Won-Chul Lee, Julie George, ...> ;Nature Communications. 2021 Nov 17
• 37 citations
  Nodal immune flare mimics nodal disease progression following neoadjuvant immune checkpoint inhibitors in non-small cell lung cancer.
  Tina Cascone, Annikka Weissferdt, Myrna C.B. Godoy, William N. William, Cheuk Hong Leung, Heather Lin, Sreyashi Basu, Shalini S. Yadav, Apar Pataer, Kyle G. Mitchell, ...> ;Nature Communications. 2021 Aug 19
• 31 citations
  Immune evasion in HPV− head and neck precancer–cancer transition is driven by an aneuploid switch involving chromosome 9p loss
  William N. William, Xin Zhao, Joy J. Bianchi, Heather Lin, Pan Cheng, J. Jack Lee, Hannah Carter, Ludmil B. Alexandrov, Jim Abraham, David Spetzler, Steven M. Dubinett...> ;Proceedings of the National Academy of Sciences of the United States of America. 2021 May 11
• 17 citations
  Direct costs associated with the management of mucositis: A systematic review.
  Leticia Rodrigues-Oliveira, Luiz Paulo Kowalski, Marcos Santos, Gustavo Nader Marta, René-Jean Bensadoun, Manoela Domingues Martins, Márcio Ajudarte Lopes, Gilberto de...> ;Oral Oncology. 2021 Apr 29
• 14 citations
  Impact of the COVID-19 Pandemic on Oncology Clinical Research in Latin America (LACOG 0420).
  Aline Bobato Lara Gongora, Gustavo Werutsky, Denis Leonardo Fontes Jardim, Angélica Nogueira-Rodrigues, Carlos Barrios, Clarissa Mathias, Fernando C. Maluf, Rachel P. ...> ;JCO Global Oncology. 2021 Apr 1
• 300 citations
  Neoadjuvant nivolumab or nivolumab plus ipilimumab in operable non-small cell lung cancer: the phase 2 randomized NEOSTAR trial.
  Tina Cascone, William N. William, Annikka Weissferdt, Cheuk Hong Leung, Heather Lin, Apar Pataer, Myrna C.B. Godoy, Brett W. Carter, Lorenzo Federico, Alexandre Reuben...> ;Nature Medicine. 2021 Feb 18
• 9 citations
  A Phase 1b trial of prexasertib in combination with chemoradiation in patients with locally advanced head and neck squamous cell carcinoma.
  Eddy S. Yang, Eric Deutsch, Altan Mehmet, Jérôme Fayette, Yungan Tao, Lisle Nabell, Sharon A. Spencer, Xuejing A. Wang, Elizabeth A. Spoljoric, Wei Zhang, Scott M. Hyn...> ;Radiotherapy and Oncology. 2021 Feb 9
• 7 citations
  Oral leukoplakia and erythroplakia in young patients: a systematic review.
  Ana Luiza Oliveira Corrêa Roza, Luiz Paulo Kowalski, William N. William, Gilberto de Castro, Aline Lauda Freitas Chaves, Anna Luíza Damaceno Araújo, Ana Carolina Prado...> ;Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. 2021 Jan 1
• 3 citations
  Immune manifestations with checkpoint inhibitors in a single Brazilian center: experience and literature review.
  Rafael Schmerling, Antonio C. Buzaid, Carolina Kawamura Haddad, Fabio Ab Schutz, Fábio Roberto Kater, Juliana Martins Pimenta, Fernando C. Maluf, William N. William, C...> ;Future Science OA. 2021 Jan 1
• 3 citations
  Impact of the COVID-19 Pandemic on Physicians Working in the Head and Neck Field
  Rui Imamura, Ricardo Ferreira Bento, Leandro Luongo de Matos, William N. William, Gustavo Nader Marta, Aline Lauda Freitas Chaves, Gilberto de Castro, Luiz Paulo Kowalski> ;International Archives of Otorhinolaryngology. 2021 Jan 1
• 14 citations
  Targeting of CD40 and PD-L1 Pathways Inhibits Progression of Oral Premalignant Lesions in a Carcinogen-induced Model of Oral Squamous Cell Carcinoma.
  Jose Augusto Monteiro de Oliveira Novaes, Taghreed Hirz, Irene Guijarro, Monique B. Nilsson, Marlese Pisegna, Alissa Poteete, Hampartsoum B. Barsoumian, Jared J. Frade...> ;Cancer Prevention Research. 2021 Mar 1
• 27 citations
  Global prevalence of human papillomavirus-driven oropharyngeal squamous cell carcinoma following the ASCO guidelines: A systematic review and meta-analysis.
  Bruno Augusto Linhares Almeida Mariz, Luiz Paulo Kowalski, William N. William, Gilberto de Castro, Aline Lauda Freitas Chaves, Marcos Santos, Thiago Bueno Oliveira, An...> ;Critical Reviews in Oncology/hematology. 2020 Oct 25
• 20 citations
  18F-fluorodeoxyglucose positron emission tomography correlates with tumor immunometabolic phenotypes in resected lung cancer
  Kyle G. Mitchell, Behrang Amini, Yunfei Wang, Brett W. Carter, Myrna C.B. Godoy, Edwin R. Parra, Carmen Behrens, Pamela Villalobos, Alexandre Reuben, J. Jack Lee, Anni...> ;Cancer Immunology, Immunotherapy. 2020 Apr 16
• 20 citations
  A Phase I/II Study of Neoadjuvant Cisplatin, Docetaxel, and Nintedanib for Resectable Non-Small Cell Lung Cancer.
  Tina Cascone, Boris Sepesi, Heather Lin, Neda Kalhor, Edwin R. Parra, Mei Jiang, Myrna C.B. Godoy, Jianjun Zhang, Frank V. Fossella, Anne S. Tsao, Vincent K. Lam, Char...> ;Clinical Cancer Research. 2020 Mar 19
• 15 citations
  Weekly paclitaxel, carboplatin, cetuximab, and cetuximab, docetaxel, cisplatin, and fluorouracil, followed by local therapy in previously untreated, locally advanced h...
  Robert I. Haddad, Erminia Massarelli, J. Jack Lee, H. Lin, Katherine A. Hutcheson, Jeff Lewis, Adam S. Garden, George R. Blumenschein, William N. William, Rebecca Phar...> ;Annals of Oncology. 2019 Mar 1
• 287 citations
  Combining Immune Checkpoint Blockade and Tumor-Specific Vaccine for Patients With Incurable Human Papillomavirus 16-Related Cancer: A Phase 2 Clinical Trial.
  Erminia Massarelli, William N. William, Faye M. Johnson, Merrill S. Kies, Renata Ferrarotto, Ming Guo, Lei Feng, J. Jack Lee, Hai T. Tran, Young Uk Kim, Cara Haymaker,...> ;JAMA Oncology. 2019 Jan 1
• 4 citations
  PI3-kinase pathway biomarkers in oral cancer and tumor immune cells.
  Mohammad Y. Ibrahim, Maria I. Nunez, Nusrat Harun, J. Jack Lee, Adel K. El-Naggar, Renata Ferrarotto, Ignacio I. Wistuba, Jeffrey N. Myers, Bonnie S. Glisson, William ...> ;Head & Neck. 2018 Dec 16
• 246 citations
  Landscape of EGFR-Dependent and -Independent Resistance Mechanisms to Osimertinib and Continuation Therapy Beyond Progression in EGFR-Mutant NSCLC.
  Xiuning Le, Sonam Puri, Marcelo V. Negrao, Monique B. Nilsson, Jacqulyne P. Robichaux, Theresa A. Boyle, J. Kevin Hicks, Katherine L. Lovinger, Emily Roarty, Waree Rin...> ;Clinical Cancer Research. 2018 Dec 15
• 23 citations
  Evaluation of classical clinical endpoints as surrogates for overall survival in patients treated with immune checkpoint blockers: a systematic review and meta-analysis
  Howard L. Kaufman, Lawrence H. Schwartz, William N. William, Mario Sznol, Kyle Fahrbach, Yingxin Xu, Eric Masson, Andrea Leninka Vergara-Silva> ;Journal of Cancer Research and Clinical Oncology. 2018 Aug 21
• 16 citations
  Randomized phase II trial of cixutumumab alone or with cetuximab for refractory recurrent/metastatic head and neck squamous cell carcinoma.
  Renata Ferrarotto, William N. William, Jennifer E. Tseng, Shanthi Marur, Dong M. Shin, Barbara A. Murphy, Ezra E.W. Cohen, Christopher Y. Thomas, Richard Willey, Jan C...> ;Oral Oncology. 2018 May 19
• 105 citations
  Effect of neoadjuvant chemotherapy on the immune microenvironment in non-small cell lung carcinomas as determined by multiplex immunofluorescence and image analysis ap...
  Edwin Roger Parra, Pamela Villalobos, Carmen Behrens, Mei Jiang, Apar Pataer, Stephen G. Swisher, William N. William, Jiexin Zhang, Jack Lee, Tina Cascone, John V. Hey...> ;Journal for Immunotherapy of Cancer. 2018 Jun 6
• 77 citations
  Erlotinib in the treatment of recurrent or metastatic cutaneous squamous cell carcinoma: A single-arm phase 2 clinical trial
  Kathryn A. Gold, Merrill S. Kies, William N. William, Faye M. Johnson, J. Jack Lee, Bonnie S. Glisson> ;Cancer. 2018 May 15
• 14 citations
  Single Arm, Phase II Study of Cisplatin, Docetaxel, and Erlotinib in Patients with Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinomas
  William N. William, Anne S. Tsao, Lei Feng, Lawrence E. Ginsberg, J. Jack Lee, Merrill S. Kies, Bonnie S. Glisson, Edward S. Kim> ;The Oncologist. 2018 May 1
• 51 citations
  Evaluation of Prexasertib, a Checkpoint Kinase 1 Inhibitor, in a Phase Ib Study of Patients with Squamous Cell Carcinoma.
  David S. Hong, Kathleen N. Moore, Manish R. Patel, Stefan C. Grant, Howard A. Burris, William N. William, Suzanne F. Jones, Funda Meric-Bernstam, Jeffrey R. Infante, L...> ;Clinical Cancer Research. 2018 Apr 11
• 17 citations
  Met Receptor Tyrosine Kinase and Chemoprevention of Oral Cancer
  Pierre Saintigny, William N. William, Jean Philippe Foy, Vassiliki A. Papadimitrakopoulou, Wenhua Lang, Li Zhang, You Hong Fan, Lei Feng, Edward S. Kim, Adel K. El-Nag...> ;Journal of the National Cancer Institute. 2018 Mar 1
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Journal Articles

• PI3‐Kinase Pathway Biomarkers in Oral Cancer and Tumor Immune Cells  
  Bonnie S Glisson, Jeffrey Myers, N Jr William, Renata Ferrarotto, Head & Neck
• Combining Immune Checkpoint Blockade and Tumor-Specific Vaccine for Patients with Incurable Human Papillomavirus 16–Related Cancer  
  Erminia Massarelli, William William, Ming Guo, Merrill Kies, Bonnie Glisson, Hai Tran, Faye Johnson, Renata Ferrarotto, Lei Feng, JAMA
• Landscape of EGFR -Dependent and -Independent Resistance Mechanisms to Osimertinib and Continuation Therapy Post-Progression in EGFR-Mutant NSCLC  
  Stephen G Swisher, Vassiliki A Papadimitrakopoulou, John V Heymach, Jack A Roth, Jianjun Zhang, William N William, Bonnie S Glisson, Clinical Cancer Research

Lectures

• Genomic and transcriptomic landscape of oral pre-cancers (OPCs) and risk of oral cancer (OC). 
  2019 ASCO Annual Meeting - 6/1/2019
• Probing the Depths of Immunotherapy: More Than Survival 
  2018 ASCO Annual Meeting - Chicago, Illinois - 06/2/2018