XuanHuangMDPhD

PubMed

• Improved false-negative rates using a novel patient selection flowchart in initially biopsy-proven node-positive breast cancer undergoing blue-dye alone guided sentine...
  Minyan Chen, Shengmei Li, Meng Huang, Jingjing Guo, Xuan Huang, Wenhui Guo, Lili Chen, Yuxiang Lin, Lisa Jacobs, Chuan Wang, Fangmeng Fu> ;Breast Cancer Research and Treatment. 2022 Nov 1
• 1 citations
  RASSF1A Suppression as a Potential Regulator of Mechano-Pathobiology Associated with Mammographic Density in BRCA Mutation Carriers.
  Gina Reye, Xuan Huang, Kara L. Britt, Christoph Meinert, Tony Blick, Yannan Xu, Konstantin I. Momot, Thomas Lloyd, Jason J. Northey, Erik W. Thompson, Honor J. Hugo> ;Cancers. 2021 Jun 29
• 14 citations
  Detection of Histone H2AX Phosphorylation on Ser-139 as an Indicator of DNA Damage
  Hong Zhao, Xuan Huang, H. Dorota Halicka, Zbigniew Darzynkiewicz> ;Current Protocols in Cytometry. 2019 Jun 1
• 19 citations
  Venous thromboembolism laboratory testing (factor V Leiden and factor II c.*97G>A), 2018 update: a technical standard of the American College of Medical Genetics and G...
  Shulin Zhang, Annette K. Taylor, Xuan Huang, Biao Luo, Elaine B. Spector, Ping Fang, C. Sue Richards> ;Genetics in Medicine. 2018 Oct 5
• 6 citations
  Analysis of Cellular DNA Content by Flow Cytometry.
  Zbigniew Darzynkiewicz, Xuan Huang, Hong Zhao> ;Current Protocols in Immunology. 2017 Nov 1
• 3 citations
  Analysis of Cellular DNA Content by Flow Cytometry.
  Zbigniew Darzynkiewicz, Xuan Huang, Hong Zhao> ;Current Protocols in Cytometry. 2017 Oct 2
• 73 citations
  Characterization of Clinical Cases of Advanced Papillary Renal Cell Carcinoma via Comprehensive Genomic Profiling.
  Sumanta K. Pal, Siraj M. Ali, Evgeny Yakirevich, Daniel M. Geynisman, Jose A. Karam, Julia A. Elvin, Garrett M. Frampton, Xuan Huang, Douglas I. Lin, Margaret Rosenzwe...> ;European Urology. 2018 Jan 1
• 22 citations
  Phase II trial of docetaxel, bevacizumab, lenalidomide and prednisone in patients with metastatic castration-resistant prostate cancer.
  Ravi A. Madan, Fatima Karzai, Yang-Min Ning, Bamidele Adesunloye, Xuan Huang, Nancy Harold, Anna Couvillon, Guinevere Chun, Lisa M. Cordes, Tristan M. Sissung, Shaunna...> ;BJU International. 2016 Oct 1
• 32 citations
  Challenges to improved therapeutics for metastatic castrate resistant prostate cancer: from recent successes and failures.
  Xuan Huang, Cindy H. Chau, William D. Figg> ;Journal of Hematology & Oncology. 2012 Jul 2
• 21 citations
  Severe toxicity of skin rash, fever and diarrhea associated with imatinib: case report and review of skin toxicities associated with tyrosine kinase inhibitors
  Xuan Huang, Samir Patel, Nasir Ahmed, Karen Seiter, Delong Liu> ;Drug Design, Development and Therapy. 2008 Oct 27
• 173 citations
  Cytometry of ATM Activation and Histone H2AX Phosphorylation to Estimate Extent of DNA Damage Induced by Exogenous Agents
  Toshiki Tanaka, Xuan Huang, H. Dorota Halicka, Hong Zhao, Frank Traganos, Anthony P. Albino, Wei Dai, Zbigniew Darzynkiewicz> ;Cytometry. Part A. 2007 Sep 1
• 39 citations
  ATM activation accompanies histone H2AX phosphorylation in A549 cells upon exposure to tobacco smoke
  Toshiki Tanaka, Xuan Huang, Ellen D. Jorgensen, Diana Gietl, Frank Traganos, Zbigniew Darzynkiewicz, Anthony P. Albino> ;BMC Cell Biology. 2007 Jun 26
• 169 citations
  Constitutive histone H2AX phosphorylation and ATM activation, the reporters of DNA damage by endogenous oxidants.
  Toshiki Tanaka, H. Dorota Halicka, Xuan Huang, Frank Traganos, Zbigniew Darzynkiewicz> ;Cell Cycle. 2006 Sep 1
• 22 citations
  Extent of constitutive histone H2AX phosphorylation on Ser-139 varies in cells with different TP53 status.
  Toshiki Tanaka, Akira Kurose, Xuan Huang, Frank Traganos, Wei Dai, Zbigniew Darzynkiewicz> ;Cell Proliferation. 2006 Aug 1
• 60 citations
  Constitutive histone H2AX phosphorylation on Ser-139 in cells untreated by genotoxic agents is cell-cycle phase specific and attenuated by scavenging reactive oxygen s...
  Xuan Huang, Toshiki Tanaka, Akira Kurose, Frank Traganos, Zbigniew Darzynkiewicz> ;International Journal of Oncology. 2006 Aug 1
• 26 citations
  Nitrogen Oxide-Releasing Aspirin Induces Histone H2AX Phosphorylation, ATM Activation and Apoptosis Preferentially in S-Phase Cells: Involvement of Reactive Oxygen Spe...
  Toshiki Tanaka, Akira Kurose, H. Dorota Halicka, Xuan Huang, Frank Traganos, Zbigniew Darzynkiewicz> ;Cell Cycle. 2006 Jul 13
• 38 citations
  Induction of DNA double-strand breaks in A549 and normal human pulmonary epithelial cells by cigarette smoke is mediated by free radicals.
  Anthony P. Albino, Xuan Huang, Ellen D. Jorgensen, Diana Gietl, Frank Traganos, Zbigniew Darzynkiewicz> ;International Journal of Oncology. 2006 Jun 1
• 56 citations
  Synchronization in the cell cycle by inhibitors of DNA replication induces histone H2AX phosphorylation: an indication of DNA damage
  Akira Kurose, Toshiki Tanaka, Xuan Huang, Frank Traganos, Zbigniew Darzynkiewicz> ;Cell Proliferation. 2006 Jun 1
• 37 citations
  Activation of ATM and histone H2AX phosphorylation induced by mitoxantrone but not by topotecan is prevented by the antioxidant N-acetyl-L-cysteine.
  Xuan Huang, Akira Kurose, Toshiki Tanaka, Frank Traganos, Wei Dai, Zbigniew Darzynkiewicz> ;Cancer Biology & Therapy. 2006 May 26
• 92 citations
  Contribution of p16INK4a and p21CIP1 pathways to induction of premature senescence of human endothelial cells: permissive role of p53
  Jun Chen, Xuan Huang, Dorota Halicka, Sergey V. Brodsky, Ari Avram, Jonathan Eskander, Noah A. Bloomgarden, Zbigniew Darzynkiewicz, Michael S. Goligorsky> ;American Journal of Physiology. Heart and Circulatory Physiology. 2006 Apr 1
• 51 citations
  Effects of hydroxyurea and aphidicolin on phosphorylation of ataxia telangiectasia mutated on Ser 1981 and histone H2AX on Ser 139 in relation to cell cycle phase and ...
  Akira Kurose, Toshiki Tanaka, Xuan Huang, Frank Traganos, Wei Dai, Zbigniew Darzynkiewicz> ;Cytometry. Part A. 2006 Apr 1
• 42 citations
  Sequential phosphorylation of Ser-10 on histone H3 and ser-139 on histone H2AX and ATM activation during premature chromosome condensation: relationship to cell-cycle ...
  Xuan Huang, Akira Kurose, Toshiki Tanaka, Frank Traganos, Wei Dai, Zbigniew Darzynkiewicz> ;Cytometry. Part A. 2006 Apr 1
• 52 citations
  ATM activation and histone H2AX phosphorylation as indicators of DNA damage by DNA topoisomerase I inhibitor topotecan and during apoptosis.
  Toshiki Tanaka, Akira Kurose, Xuan Huang, Wei Dai, Zbigniew Darzynkiewicz> ;Cell Proliferation. 2006 Feb 1
• 28 citations
  Detection of DNA Strand Breaks by Flow and Laser Scanning Cytometry in Studies of Apoptosis and Cell Proliferation (DNA Replication)
  Zbigniew Darzynkiewicz, Xuan Huang, Masaki Okafuji> ;Methods in Molecular Biology. 2006 Jan 1
• 107 citations
  Cytometric assessment of histone H2AX phosphorylation: a reporter of DNA damage.
  Xuan Huang, Zbigniew Darzynkiewicz> ;Methods in Molecular Biology. 2006 Jan 1
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Journal Articles

• Venous Thromboembolism Laboratory Testing (Factor V Leiden and Factor II C.*97G>A), 2018 Update: A Technical Standard of the American College of Medical Genetics and G...  
  Xuan Huang, Nature