YaomingWangMD

PubMed

• 11 citations
  Protection of ischemic white matter and oligodendrocytes in mice by 3K3A-activated protein C.
  Mikko T Huuskonen, Yaoming Wang, Angeliki M. Nikolakopoulou, Axel Montagne, Zhonghua Dai, Divna Lazic, Abhay P. Sagare, Zhen Zhao, José A. Fernández, John H. Griffin, ...> ;The Journal of Experimental Medicine. 2022 Jan 3
• 50 citations
  Endothelial LRP1 protects against neurodegeneration by blocking cyclophilin A.
  Angeliki M. Nikolakopoulou, Yaoming Wang, Qingyi Ma, Abhay P. Sagare, Axel Montagne, Mikko T Huuskonen, Sanket V Rege, Kassandra Kisler, Zhonghua Dai, Jakob Körbelin, ...> ;The Journal of Experimental Medicine. 2021 Apr 5
• 49 citations
  Channelrhodopsin Excitation Contracts Brain Pericytes and Reduces Blood Flow in the Aging Mouse Brain in vivo.
  Amy R. Nelson, Meghana A. Sagare, Yaoming Wang, Kassandra Kisler, Zhen Zhao, Berislav V. Zlokovic> ;Frontiers in Aging Neuroscience. 2020 Apr 29
• 33 citations
  Identification and therapeutic rescue of autophagosome and glutamate receptor defects in C9ORF72 and sporadic ALS neurons
  Yingxiao Shi, Shu-Ting Hung, Gabriel Rocha, Shaoyu Lin, Gabriel R. Linares, Kim A. Staats, Carina Seah, Yaoming Wang, Michael Chickering, Jesse D. Lai, Tohru Sugawara,...> ;JCI Insight. 2019 Aug 8
• 207 citations
  Pericyte loss leads to circulatory failure and pleiotrophin depletion causing neuron loss.
  Angeliki M. Nikolakopoulou, Axel Montagne, Kassandra Kisler, Zhonghua Dai, Yaoming Wang, Mikko T Huuskonen, Abhay P. Sagare, Divna Lazic, Melanie D. Sweeney, Pan Kong,...> ;Nature Neuroscience. 2019 Jun 24
• 32 citations
  TRIM9-Mediated Resolution of Neuroinflammation Confers Neuroprotection upon Ischemic Stroke in Mice
  Jianxiong Zeng, Yaoming Wang, Zhifei Luo, Lin-Chun Chang, Ji-Seung Yoo, Huan Yan, Younho Choi, Xiaochun Xie, Benjamin E. Deverman, Viviana Gradinaru, Stephanie L. Gupt...> ;Cell Reports. 2019 Apr 9
• 68 citations
  PAR1 biased signaling is required for activated protein C in vivo benefits in sepsis and stroke.
  Ranjeet Kumar Sinha, Yaoming Wang, Zhen Zhao, Xiao Xu, Laurent Burnier, Naveen Gupta, José A. Fernández, Greg S. Martin, Sergey Kupriyanov, Laurent O. Mosnier, Berisla...> ;Blood. 2018 Mar 15
• 354 citations
  Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons.
  Yingxiao Shi, Shaoyu Lin, Kim A. Staats, Yichen Li, Wen-Hsuan Chang, Shu Ting Hung, Eric Hendricks, Gabriel R. Linares, Yaoming Wang, Esther Y. Son, Xinmei Wen, Kassan...> ;Nature Medicine. 2018 Feb 5
• 253 citations
  Pericyte degeneration causes white matter dysfunction in the mouse central nervous system.
  Axel Montagne, Angeliki M. Nikolakopoulou, Zhen Zhao, Abhay P. Sagare, Gabriel Si, Divna Lazic, Samuel Barnes, Madelaine Daianu, Anita Ramanathan, Ariel Go, Erica J. L...> ;Nature Medicine. 2018 Feb 5
• 16 citations
  Can adjunctive therapies augment the efficacy of endovascular thrombolysis? A potential role for activated protein C
  Arun P. Amar, Abhay P. Sagare, Zhen Zhao, Yaoming Wang, Amy R. Nelson, John H. Griffin, Berislav V. Zlokovic> ;Neuropharmacology. 2017 Sep 17
• 321 citations
  Pericyte degeneration leads to neurovascular uncoupling and limits oxygen supply to brain
  Kassandra Kisler, Amy R. Nelson, Sanket V Rege, Anita Ramanathan, Yaoming Wang, Ashim Ahuja, Divna Lazic, Philbert S. Tsai, Zhen Zhao, Yi Zhou, David A. Boas, Sava Sak...> ;Nature Neuroscience. 2017 Mar 1
• 71 citations
  3K3A-activated protein C stimulates postischemic neuronal repair by human neural stem cells in mice.
  Yaoming Wang, Zhen Zhao, Sanket V Rege, Min Wang, Gabriel Si, Yi Zhou, Su Wang, John H. Griffin, Steven A. Goldman, Berislav V. Zlokovic> ;Nature Medicine. 2016 Aug 22
• 172 citations
  Blood–spinal cord barrier disruption contributes to early motor-neuron degeneration in ALS-model mice
  Ethan A. Winkler, Jesse D. Sengillo, Abhay P. Sagare, Zhen Zhao, Qingyi Ma, Edward Zuniga, Yaoming Wang, Zhihui Zhong, John S. Sullivan, John H. Griffin, Don W. Clevel...> ;Proceedings of the National Academy of Sciences of the United States of America. 2014 Mar 18
• 50 citations
  Activated Protein C Analog Protects From Ischemic Stroke and Extends the Therapeutic Window of Tissue-Type Plasminogen Activator in Aged Female Mice and Hypertensive Rats
  Yaoming Wang, Zhen Zhao, Nienwen Chow, Padmesh S. Rajput, John H. Griffin, Patrick D. Lyden, Berislav V. Zlokovic> ;Stroke. 2013 Dec 1
• 9 citations
  Neurotoxicity of the anticoagulant-selective E149A-activated protein C variant after focal ischemic stroke in mice
  Yaoming Wang, Ranjeet Kumar Sinha, Laurent O. Mosnier, John H. Griffin, Berislav V. Zlokovic> ;Blood Cells, Molecules & Diseases. 2013 Aug 1
• 23 citations
  Activated protein C analog promotes neurogenesis and improves neurological outcome after focal ischemic stroke in mice via protease activated receptor 1.
  Yaoming Wang, Zhen Zhao, Nienwen Chow, Tracy Ali, John H. Griffin, Berislav V. Zlokovic> ;Brain Research. 2013 Apr 24
• 59 citations
  An Activated Protein C Analog With Reduced Anticoagulant Activity Extends the Therapeutic Window of Tissue Plasminogen Activator for Ischemic Stroke in Rodents
  Yaoming Wang, Zhenggang Zhang, Nienwen Chow, Thomas P. Davis, John H. Griffin, Michael Chopp, Berislav V. Zlokovic> ;Stroke. 2012 Sep 1
• 47 citations
  Protein S Protects Neurons from Excitotoxic Injury by Activating the TAM Receptor Tyro3–Phosphatidylinositol 3-Kinase–Akt Pathway through Its Sex Hormone-Binding Globu...
  Zhihui Zhong, Yaoming Wang, Huang Guo, Abhay P. Sagare, José A. Fernández, Robert D. Bell, Theresa M Barrett, John H. Griffin, Robert S. Freeman, Berislav V. Zlokovic> ;The Journal of Neuroscience. 2010 Nov 17
• 87 citations
  Protein S controls hypoxic/ischemic blood-brain barrier disruption through the TAM receptor Tyro3 and sphingosine 1-phosphate receptor
  Donghui Zhu, Yaoming Wang, Itender Singh, Robert D. Bell, Rashid Deane, Zhihui Zhong, Abhay P. Sagare, Ethan A. Winkler, Berislav V. Zlokovic> ;Blood. 2010 Jun 10
• Is obesity becoming a public health problem in India? Examine the shift from under- to overnutrition problems over time.
  Wang, Y.,Chen, H. J.,Shaikh, S.,Mathur, P.> ;Obes Rev. 2009 Apr 25
• 43 citations
  Differential Neuroprotection and Risk for Bleeding From Activated Protein C With Varying Degrees of Anticoagulant Activity
  Yaoming Wang, Meenakshisundaram Thiyagarajan, Nienwen Chow, Itender Singh, Huang Guo, Thomas P. Davis, Berislav V. Zlokovic> ;Stroke. 2009 May 1
• 29 citations
  Species-dependent neuroprotection by activated protein C mutants with reduced anticoagulant activity.
  Huang Guo, Yaoming Wang, Itender Singh, Dong Liu, José A. Fernández, John H. Griffin, Nienwen Chow, Berislav V. Zlokovic> ;Journal of Neurochemistry. 2009 Apr 1
• 69 citations
  Neuroprotective activities of activated protein C mutant with reduced anticoagulant activity.
  Huang Guo, Itender Singh, Yaoming Wang, Rashid Deane, Theresa M Barrett, José A. Fernández, Nienwen Chow, John H. Griffin, Berislav V. Zlokovic> ;The European Journal of Neuroscience. 2009 Mar 1
• 22 citations
  Neurogenesis associated with endothelin-induced cortical infarction in the mouse.
  Yaoming Wang, Kunlin Jin, David A. Greenberg> ;Brain Research. 2007 Sep 5
• 147 citations
  VEGF-overexpressing transgenic mice show enhanced post-ischemic neurogenesis and neuromigration.
  Yaoming Wang, Kunlin Jin, Xiao Ou Mao, Lin Xie, Surita Banwait, Hugo H. Marti, David A. Greenberg> ;Journal of Neuroscience Research. 2007 Mar 1
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