YelenaYJanjigianMD

PubMed

• The Role of the TP53 Pathway in Predicting Response to Neoadjuvant Therapy in Esophageal Adenocarcinoma.
  Smita Sihag, Samuel C Nussenzweig, Henry S Walch, Meier Hsu, Kay See Tan, Sergio De La Torre, Yelena Y Janjigian, Steven B Maron, Geoffrey Y Ku, Laura H Tang, Pari M S...> ;Clinical cancer research : an official journal of the American Association for Cancer Research. 2022 Jun 13
• MATTERHORN: phase III study of durvalumab plus FLOT chemotherapy in resectable gastric/gastroesophageal junction cancer.
  Yelena Y Janjigian, Eric Van Cutsem, Kei Muro, Zev Wainberg, Salah-Eddin Al-Batran, Woo Jin Hyung, Daniela Molena, Michelle Marcovitz, Dario Ruscica, Scott H Robbins, ...> ;Future oncology (London, England). 2022 Jun 1
• Caveolin-1 temporal modulation enhances antibody drug efficacy in heterogeneous gastric cancer.
  Patrícia M R Pereira, Komal Mandleywala, Sébastien Monette, Melissa Lumish, Kathryn M Tully, Sandeep Surendra Panikar, Mike Cornejo, Audrey Mauguen, Ashwin Ragupathi, ...> ;Nature communications. 2022 May 9
• ATM Germline-Mutated Gastroesophageal Junction Adenocarcinomas: Clinical Descriptors, Molecular Characteristics, and Potential Therapeutic Implications.
  Tony El Jabbour, Maksym Misyura, Darren Cowzer, Michal Zimmermann, Victoria Rimkunas, Antonio Marra, Fatemeh Derakhshan, Pier Selenica, Megan Parilla, Jeremy S Setton,...> ;Journal of the National Cancer Institute. 2022 May 9
• 1 citations
  Defining and Targeting Esophagogastric Cancer Genomic Subsets With Patient-Derived Xenografts.
  Ryan H Moy, Henry S Walch, Marissa Mattar, Walid K Chatila, Daniela Molena, Vivian E Strong, Laura H Tang, Steven B Maron, Daniel G Coit, David R Jones, Jaclyn F Hecht...> ;JCO precision oncology. 2022 Feb 1
• Distinct Differences in Gastroesophageal Junction and Gastric Adenocarcinoma in 2194 Patients: In Memory of Rebecca A. Carr, February 24, 1988-January 19, 2021.
  Masaya Nakauchi, Elvira L. Vos, Rebecca Carr, Arianna Barbetta, Laura H. Tang, Mithat Gonen, Ashley E. Russo, Yelena Y. Janjigian, Sam S. Yoon, Smita Sihag, Valerie W....> ;Annals of Surgery. 2021 Nov 29
• Pharmacologically controlling protein-protein interactions through epichaperomes for therapeutic vulnerability in cancer.
  Suhasini Joshi, Erica DaGama Gomes, Tai Wang, Adriana D. Corben, Tony Taldone, Srinivasa Gandu, Chao Xu, Sahil Sharma, Salma Buddaseth, Pengrong Yan, Lon Yin L. Chan, ...> ;Communications biology. 2021 Nov 25
• Prognosis after neoadjuvant chemoradiation or chemotherapy for locally advanced gastro-oesophageal junctional adenocarcinoma.
  Elvira L. Vos, Rebecca Carr, Meier Hsu, Masaya Nakauchi, T Nobel, A Russo, Arianna Barbetta, Kay See Tan, Laura H. Tang, D. Ilson, Geoffrey Y. Ku, Abraham J. Wu, Yelen...> ;British Journal of Surgery. 2021 Nov 11
• Induction FOLFOX and PET-Directed Chemoradiation For Locally Advanced Esophageal Adenocarcinoma
  Rebecca Carr, Meier Hsu, Caitlin Harrington, Kay See Tan, Manjit S. Bains, Matthew J. Bott, David H. Ilson, James M. Isbell, Yelena Y. Janjigian, Steven B Maron, Berna...> ;Annals of Surgery. 2021 Aug 13
• A nutritional management algorithm in older patients with locally advanced esophageal cancer.
  Ryan H. Moy, Shalom Sabwa, Steven Brad Maron, Marina Shcherba, Arlyn Apollo, Yelena Y. Janjigian, Geoffrey Y. Ku, William P. Tew, Abraham J. Wu, David R. Jones, Daniel...> ;Journal of Geriatric Oncology. 2021 Aug 12
• 2 citations
  Quality of life with first-line pembrolizumab for PD-L1-positive advanced gastric/gastroesophageal junction adenocarcinoma: results from the randomised phase III KEYNO...
  E. Van Cutsem, A. Valderrama, Y-J. Bang, Charles S. Fuchs, K. Shitara, Yelena Y. Janjigian, S. Qin, T.G. Larson, Veena Shankaran, Stacey Stein, Josephine M. Norquist, ...> ;ESMO open. 2021 Aug 1
• 3 citations
  Prevalence of Germline Alterations on Targeted Tumor-Normal Sequencing of Esophagogastric Cancer.
  Geoffrey Y. Ku, Yelena Kemel, Steve B. Maron, Joanne F. Chou, Vignesh Ravichandran, Zarina Shameer, Anna Maio, Elizabeth Won, David P. Kelsen, David H. Ilson, Marinela...> ;JAMA network open. 2021 Jul 1
• 3 citations
  Eradicating micrometastases with immune checkpoint blockade: Strike while the iron is hot.
  Yelena Y. Janjigian, Jedd D. Wolchok, Charlotte E. Ariyan> ;Cancer Cell. 2021 Jun 14
• 162 citations
  First-line nivolumab plus chemotherapy versus chemotherapy alone for advanced gastric, gastro-oesophageal junction, and oesophageal adenocarcinoma (CheckMate 649): a r...
  Yelena Y. Janjigian, Kohei Shitara, Markus Moehler, Marcelo Garrido, Pamela Salman, Lin Shen, Lucjan Wyrwicz, Kensei Yamaguchi, Tomasz Skoczylas, Arinilda Silva Campos...> ;The Lancet. 2021 Jul 3
• 7 citations
  Randomized Phase II Study of PET Response-Adapted Combined Modality Therapy for Esophageal Cancer: Mature Results of the CALGB 80803 (Alliance) Trial.
  Karyn A. Goodman, Fang-Shu Ou, Nathan Hall, Tanios Bekaii-Saab, Briant Fruth, Erin Twohy, Michael O. Meyers, Daniel J. Boffa, Kisha Mitchell, Wendy L. Frankel, Donna N...> ;Journal of Clinical Oncology. 2021 Jun 2
• 2 citations
  KEYNOTE-859: a Phase III study of pembrolizumab plus chemotherapy in gastric/gastroesophageal junction adenocarcinoma.
  Josep Tabernero, Yung-Jue Bang, Eric Van Cutsem, Charles S. Fuchs, Yelena Y. Janjigian, Pooja Bhagia, Kan Li, David Adelberg, S. Qin> ;Future Oncology. 2021 May 12
• 1 citations
  ASO Visual Abstract: Association of Obesity with Worse Operative and Oncologic Outcomes Among Patients Undergoing Gastric Cancer Resection
  Masaya Nakauchi, Elvira L. Vos, Laura H. Tang, Mithat Gonen, Yelena Y. Janjigian, Geoffrey Y. Ku, David H. Ilson, Steven B Maron, Sam S. Yoon, Murray F. Brennan, Danie...> ;Annals of Surgical Oncology. 2021 Apr 24
• Association of Obesity with Worse Operative and Oncologic Outcomes for Patients Undergoing Gastric Cancer Resection.
  Masaya Nakauchi, Elvira L. Vos, Laura H. Tang, Mithat Gonen, Yelena Y. Janjigian, Geoffrey Y. Ku, David H. Ilson, Steven Brad Maron, Sam S. Yoon, Murray F. Brennan, Da...> ;Annals of Surgical Oncology. 2021 Apr 8
• 3 citations
  Next-Generation Sequencing of 487 Esophageal Adenocarcinomas Reveals Independently Prognostic Genomic Driver Alterations and Pathways.
  Smita Sihag, Samuel C Nussenzweig, Henry Walch, Meier Hsu, Kay See Tan, Francisco Sanchez-Vega, Walid K. Chatila, Sergio De La Torre, Assem Patel, Yelena Y. Janjigian,...> ;Clinical Cancer Research. 2021 Apr 1
• 23 citations
  Biomarker-targeted therapies for advanced-stage gastric and gastro-oesophageal junction cancers: an emerging paradigm.
  Yoshiaki Nakamura, Akihito Kawazoe, Florian Lordick, Yelena Y. Janjigian, Kohei Shitara> ;Nature Reviews Clinical Oncology. 2021 Mar 31
• 15 citations
  Analyses of PD-L1 and Inflammatory Gene Expression Association with Efficacy of Nivolumab ± Ipilimumab in Gastric Cancer/Gastroesophageal Junction Cancer
  Ming Lei, Nathan O. Siemers, Dimple Pandya, Han Chang, Teresa Sanchez, Christopher T. Harbison, Péter Szabó, Yelena Y. Janjigian, Patrick A. Ott, Padmanee Sharma, Joha...> ;Clinical Cancer Research. 2021 Mar 29
• 2 citations
  Treatment of Metastatic Extramammary Paget Disease with Combination Ipilimumab and Nivolumab: A Case Report
  Brendan John Guercio, Gopa Iyer, Wajih Zaheer Kidwai, Mario E. Lacouture, Soleen Ghafoor, Anthony M. Rossi, David N. Assis, Ying-Bei Chen, Klaus J. Busam, Yelena Y. Ja...> ;Case Reports in Oncology. 2021 Jan 1
• 6 citations
  Comparison of Long- and Short-term Outcomes in 845 Open and Minimally Invasive Gastrectomies for Gastric Cancer in the United States
  Masaya Nakauchi, Elvira L. Vos, Yelena Y. Janjigian, Geoffrey Y. Ku, Mark A. Schattner, Makoto Nishimura, Mithat Gonen, Daniel G. Coit, Vivian E. Strong> ;Annals of Surgical Oncology. 2021 Mar 11
• 1 citations
  Oligometastases After Curative Esophagectomy Are Not One-Size-Fits-All.
  Tamar B. Nobel, Smita Sihag, Xin Xin Xing, Mahmoud Eljalby, Meier Hsu, Kay See Tan, David B. Sewell, Manjit S. Bains, Yelena Y. Janjigian, Abraham J. Wu, Geoffrey Y. K...> ;The Annals of Thoracic Surgery. 2021 Mar 6
• 16 citations
  Safety and feasibility of esophagectomy following combined immunotherapy and chemoradiotherapy for esophageal cancer.
  Smita Sihag, Geoffrey Y. Ku, Kay See Tan, Samuel C Nussenzweig, Abraham J. Wu, Yelena Y. Janjigian, David R. Jones, Daniela Molena> ;The Journal of Thoracic and Cardiovascular Surgery. 2021 Mar 1
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Journal Articles

• Indications for Total Gastrectomy in CDH1 Mutation Carriers and Outcomes of Risk-Reducing Minimally Invasive and Open Gastrectomies  
  Sam S Yoon, Yelena Janjigian, Daniel G Coit, Zsofia K Stadler, Vivian E Strong, JAMA Surgery
• YES1 Amplification Is a Mechanism of Acquired Resistance to EGFR Inhibitors Identified by Transposon Mutagenesis and Clinical Genomics  
  Emmet J Jordan, Helena A Yu, Yelena Y Janjigian, Mark G Kris, Paul K Paik, Jamie E Chaft, Lu Wang, Gregory J Riely, Proceedings of the National Academy of Sciences

Lectures

• Biomarkers to Guide Surveillance and Adjuvant Therapy of Early-Stage Disease 
  ASCO Gastrointestinal Cancers Symposium - San Francisco, CA - 1/23/2020
• Biomarkers for Better Treatment and Patient Selection 
  ASCO Annual Meeting 2019 - Chicago, IL - 6/2/2019
• Checkpoint Blockade in Esophagogastric Cancer 
  ASCO Annual Meeting 2019 - Chicago, IL - 6/3/2019