ZacharyRayMooreMDPhD

PubMed

• 1 citations
  Association of Circulating Cardiomyocyte Cell-Free DNA With Cancer Therapy-Related Cardiac Dysfunction in Patients Undergoing Treatment for ERBB2-Positive Breast Cancer.
  Anthony F Yu, Zachary R Moore, Chaya S Moskowitz, Jennifer E Liu, Chau T Dang, Lakshmi Ramanathan, Kevin C Oeffinger, Richard M Steingart, Adam M Schmitt> ;JAMA Cardiology. 2023 Jul 1
• 3 citations
  Randomized Phase 2 Placebo-Controlled Trial of Nintedanib for the Treatment of Radiation Pneumonitis.
  Andreas Rimner, Zachary R Moore, Stephanie Lobaugh, Alexander Geyer, Daphna Y Gelblum, Raja-Elie E Abdulnour, Annemarie F Shepherd, Narek Shaverdian, Abraham J Wu, Joh...> ;International Journal of Radiation Oncology, Biology, Physics. 2023 Aug 1
• 3 citations
  Innate immune signaling drives late cardiac toxicity following DNA-damaging cancer therapies.
  Achraf Shamseddine, Suchit H Patel, Valery Chavez, Zachary R Moore, Mutayyaba Adnan, Melody Di Bona, Jun Li, Chau T Dang, Lakshmi V Ramanathan, Kevin C Oeffinger, Jenn...> ;The Journal of Experimental Medicine. 2023 Mar 6
• 15 citations
  Risk of Unplanned Hospital Encounters in Patients Treated With Radiotherapy for Head and Neck Squamous Cell Carcinoma.
  Zachary R. Moore, Nhat-Long Lam Pham, Jennifer L Shah, Lucien A. Nedzi, Baran D. Sumer, Andrew T. Day, Saad A. Khan, David J. Sher> ;Journal of Pain and Symptom Management. 2019 Apr 1
• 84 citations
  Leveraging an NQO1 Bioactivatable Drug for Tumor-Selective Use of Poly(ADP-ribose) Polymerase Inhibitors.
  Xiumei Huang, Edward A. Motea, Zachary R. Moore, Jun Yao, Ying Dong, Gaurab Chakrabarti, Jessica A. Kilgore, Molly A. Silvers, Praveen L. Patidar, Agnieszka Cholka, Fa...> ;Cancer Cell. 2016 Dec 12
• 29 citations
  Fibulin-5 Blocks Microenvironmental ROS in Pancreatic Cancer
  Miao Wang, Mary Topalovski, Jason E. Toombs, Christopher M. Wright, Zachary R. Moore, David A. Boothman, Hiromi Yanagisawa, Huamin Wang, Agnieszka K. Witkiewicz, Diego...> ;Cancer Research. 2015 Dec 1
• 46 citations
  Tumor-selective use of DNA base excision repair inhibition in pancreatic cancer using the NQO1 bioactivatable drug, β-lapachone
  Gaurab Chakrabarti, Molly A. Silvers, Mariya Ilcheva, Yuliang Liu, Zachary R. Moore, Xiuquan Luo, Jinming Gao, Glenda G. Anderson, Lili Liu, Venetia R. Sarode, David E...> ;Scientific Reports. 2015 Nov 25
• 93 citations
  Targeting glutamine metabolism sensitizes pancreatic cancer to PARP-driven metabolic catastrophe induced by ß-lapachone.
  Gaurab Chakrabarti, Zachary R. Moore, Xiuquan Luo, Mariya Ilcheva, Aktar Ali, Mahesh S. Padanad, Yunyun Zhou, Yang Xie, Sandeep Burma, Pier Paolo Scaglioni, Lewis C. C...> ;Cancer & Metabolism. 2015 Oct 12
• 16 citations
  Nanotechnology-enabled delivery of NQO1 bioactivatable drugs.
  Xinpeng Ma, Zachary R. Moore, Gang Huang, Xiumei Huang, David A. Boothman, Jinming Gao> ;Journal of Drug Targeting. 2015 Oct 9
• 72 citations
  Esterase-activatable β-lapachone prodrug micelles for NQO1-targeted lung cancer therapy.
  Xinpeng Ma, Xiumei Huang, Zachary R. Moore, Gang Huang, Jessica A. Kilgore, Yiguang Wang, Suntrea T.G. Hammer, Noelle S. Williams, David A. Boothman, Jinming Gao> ;Journal of Controlled Release. 2015 Feb 28
• 66 citations
  NAMPT inhibition sensitizes pancreatic adenocarcinoma cells to tumor-selective, PAR-independent metabolic catastrophe and cell death induced by β-lapachone.
  Zachary R. Moore, Gaurab Chakrabarti, Xiang Luo, Aktar Ali, Zeping Hu, Farjana J. Fattah, R. Vemireddy, Ralph J. DeBerardinis, Rolf A. Brekken, David A. Boothman> ;Cell Death & Disease. 2015 Jan 1
• 30 citations
  Tumor-selective, futile redox cycle-induced bystander effects elicited by NQO1 bioactivatable radiosensitizing drugs in triple-negative breast cancers.
  Lifen Cao, Long Shan Li, Christopher Spruell, Ling Xiao, Gaurab Chakrabarti, Erik A. Bey, Kathryn E. Reinicke, Melissa C. Srougi, Zachary R. Moore, Ying Dong, Peggy Vo...> ;Antioxidants & Redox Signaling. 2014 Jul 10
• 72 citations
  Catalase abrogates β-lapachone-induced PARP1 hyperactivation-directed programmed necrosis in NQO1-positive breast cancers
  Erik A. Bey, Kathryn E. Reinicke, Melissa C. Srougi, Marie E. Varnes, Vernon E. Anderson, John J. Pink, Long Shan Li, Malina Patel, Lifen Cao, Zachary R. Moore, Amy Ro...> ;Molecular Cancer Therapeutics. 2013 Jul 24
• 179 citations
  Superparamagnetic iron oxide nanoparticles: Amplifying ros stress to improve anticancer drug efficacy
  Gang Huang, Huabing Chen, Ying Dong, Xiuquan Luo, Haijun Yu, Zachary R. Moore, Erik A. Bey, David A. Boothman, Jinming Gao> ;Theranostics. 2013 Feb 1
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