Alex Huang, MD, Pediatric Hematology & Oncology, Cleveland, OH, UH Cleveland Medical Center


Pediatric Hematology & Oncology Cleveland, OH

Pediatric Solid Tumor Oncology

Professor of Pediatrics, Pathology, Biomedical Engineering & General Medical Sciences; Director of Pediatric Hematology-Oncology Fellowship Program; Theresia G. & Stuart F. Kline Family Foundation Chair in Pediatric Oncology; Co-leader, Hematopoiesis & Immune Cancer Biology Program, Case Comprehensive Cancer Center

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Education & Training

  • Johns Hopkins University
    Johns Hopkins UniversityFellowship, Pediatric Hematology/Oncology, 2000 - 2003
  • Johns Hopkins University
    Johns Hopkins UniversityResidency, Pediatrics, 1997 - 2000
  • Johns Hopkins University School of MedicinePh.D., Biochemistry, Cellular & Molecular Biology Program (Immunology Emphasis), 1990 - 1997
  • Johns Hopkins University School of Medicine
    Johns Hopkins University School of MedicineClass of 1997
  • University of ChicagoM.S., Biochemistry and Molecular Biology Program, 1988 - 1990
  • University of ChicagoB.S., Chemistry, with Honors, 1986 - 1990

Certifications & Licensure

  • OH State Medical License
    OH State Medical License 2007 - 2022
  • MD State Medical License
    MD State Medical License 2001 - 2022
  • American Board of Pediatrics Pediatrics
  • American Board of Pediatrics Pediatric Hematology-Oncology

Awards, Honors, & Recognition

  • John S. Diekhoff Award for Distinguished Graduate Mentoring Case Western Reserve University School of Graduate Studies, 2017
  • Inaugural Harrington Fellow Harrington Discovery Institute at University Hospitals, The Harrington Project for Discovery & Development, 2017
  • Cleveland Business Recognition, Best of Cleveland Awards for Research 2017
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Publications & Presentations


Journal Articles

  • Fibroblastic niches prime T cell alloimmunity through Delta-like Notch ligands  
    Chung, J., Ebens, C.L., Radojcic, V., Perkey, E., Koch, U., Scarpellino, L., Tong, A., Allen, F., Wood, S., Feng, J., Friedman, A., Granadier, D., Tran, I.T., Chai, Q...., J Clinical Investigation, 1/1/2017
  • Adoptive Natural Killer cell therapy is effective in reducing pulmonary metastasis of Ewing Sarcoma  
    Tong, A.A., Hashem, H., Eid, S., Huang, A.Y., OncoImmunology, 1/1/2017
  • Multiple administration of viral nanoparticles alter in vivo behavior - insights from intravital microscopy  
    Shukla, S., Dorand, R.D., Myers, J.T., Woods, S.E., Gulati, N.M., Stewart, P., Commandeur, U., Huang, A.Y., Steinmetz, N.F., ACS Biomaterials Science and Engineering, 1/1/2016
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Books/Book Chapters


  • CCL3 in the tumor microenvironment augments antitumor immune priming in the lymph node.
    Allen, F., Eid, S., Nthale, J., Myers J., Huang, A.Y., CRI-CIMT-EATI-AACR Cancer Immunotherapy Conference, New York, NY, 1/25/2016
  • Cdk5 disruption attenuates tumor PD-L1 expression via regulation of IFN-g signaling components and promotes anti-tumor immunity.
    Dorand, R.D., Nthale, J., Myers, J.T., Barkauskas, D.S., Avril, S., Chirieleison, S.M., Pareek, T.K., Abbott, D.W., Stearns, D.S., Letterio, J.J., Huang, A.Y., Petrosi..., CRI-CIMT-EATI-AACR Cancer Immunotherapy Conference, New York, NY, 1/25/2016
  • Quantification of lymph node transit times reveals differences in the trafficking behavior of regulatory versus conventional CD4+ T cells.
    Tong, A., Allen, F., Nair, A., Murphy, S., Huang, A.Y., CRI-CIMT-EATI-AACR Cancer Immunotherapy Conference, New York, NY, 1/25/2016
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  • Human Bone Marrow Derived Mesenchymal Stromal Cells Enhance the Number and Function of Umbilical Cord Blood Peripheral Tregs during IL-2 Driven Ex Vivo Expansion 
    2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
  • Exciting era of tumor immunology and immunotherapy 
    Albert Einstein College of Medicine, Einstein-Montefiore Clinical Research Center, Bronx, NY - 1/30/2017
  • Cdk5 as a new immunotherapeutic target 
    Tisch Cancer Institute, Mount Sinai School of Medicine, New York, NY - 1/20/2017
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Press Mentions

  • Curing Kids Cancer Gives $1.5 Million to Childhood Cancer Research Projects
    Curing Kids Cancer Gives $1.5 Million to Childhood Cancer Research ProjectsFebruary 4th, 2021

Professional Memberships

Other Languages

  • Chinese (Mandarin), Taiwanese

Hospital Affiliations