MariHashitateDallasMD

Pediatric Hematology & Oncology • Cleveland, OH

Associate Professor, Pediatrics, Case Western Reserve University School of Medicine, Rainbow Babies & Children's Hospital

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Office
UH Rainbow Babies and Children's Hospital
11100 Euclid Ave Department of Pediatrics-Hematology and Oncology
Cleveland, OH 44106
Phone+1 216-844-3951

Fax+1 216-201-6790
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Education & Training

University of WashingtonFellowship, Pediatric Hematology/Oncology, 2002 - 2005
Children's Hospital of PhiladelphiaResidency, Pediatrics, 1999 - 2002
Perelman School of Medicine at the University of PennsylvaniaClass of 1999

Certifications & Licensure

OH State Medical License 2016 - 2025
TN State Medical License 2009 - 2017
WA State Medical License 2002 - 2010
PA State Medical License 2001 - 2002
American Board of Pediatrics Pediatrics

Clinical Trials

Umbilical Cord Blood Transplantation In Patients With Hematologic Malignancies Using A Myeloablative Preparative Regimen Start of enrollment: 2011 Jun 15
Completed
Phase 2
A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs) Start of enrollment: 2011 Oct 01
Recruiting
Safety Study of Unlicensed, Investigational Cord Blood Units Manufactured by the National Cord Blood Program (NCBP) for Unrelated Transplantation Start of enrollment: 2012 Feb 01
Recruiting
Phase 2
Combined T Cell Depleted Haploidentical Peripheral Blood Stem Cell and Unrelated Umbilical Cord Blood Transplantation in Patients With Hematologic Malignancies Using a Total Lymphoid Irradiation Based Preparative Regimen Start of enrollment: 2014 Jul 11
Terminated
Phase 2
Antigen Specific Adoptive T Cell Therapy for Adenovirus Infection After Hematopoietic Stem Cell Transplantation Start of enrollment: 2019 Jan 04
Recruiting
Early Phase 1
Naive T Cell Depletion for Preventing Chronic Graft-versus-Host Disease in Children and Young Adults With Blood Cancers Undergoing Donor Stem Cell Transplant Start of enrollment: 2019 Aug 29
Recruiting
Phase 2
Roles: Contact, Principal Investigator
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Publications & Presentations

PubMed

Disease Status and Interval between Hematopoietic Cell Transplantations Predict Outcome of Pediatric Patients Who Undergo Subsequent Transplantation for Relapsed Hemat...
Epperly, R., Li, Y., Selukar, S., Zeng, E., Madden, R., Naik, S., Sharma, A., Gottschalk, S., Srinivasan, A., Mamcarz, E., Qudeimat, A., Talleur, A., Dallas, M., Tripl...> ;Transplantation and Cellular Therapy. 2024 Feb 20
4 citations
Case report: Daratumumab treatment in pre-transplant alloimmunization and severe hemolytic anemia.
Maria A Pereda, Smitha Hosahalli Vasanna, Neha J Desai, Victoria Deng, Amma Owusu-Ansah, Mari H Dallas, Irina Pateva, Jignesh Dalal> ;Frontiers in Immunology. 2022 Jan 1
87 citations
Pediatric acute lymphoblastic leukemia, version 2.2020
Patrick A. Brown, Hiroto Inaba, Colleen Annesley, Jill C. Beck, Susan Colace, Mari Dallas, Kenneth B. DeSantes, Kara M. Kelly, Carrie L. Kitko, Norman J. Lacayo, Nicol...> ;Journal of the National Comprehensive Cancer Network. 2020 Jan 1
58 citations
Pediatric patients with acute lymphoblastic leukemia generate abundant and functional neoantigen-specific CD8+ T cell responses
Anthony E. Zamora, Jeremy Chase Crawford, E. Kaitlynn Allen, Xi-zhi J. Guo, Jesse Bakke, Robert A. Carter, Hossam A. Abdelsamed, Ardiana Moustaki, Yongjin Li, Ti-Cheng...> ;Science Translational Medicine. 2019 Jun 26
8 citations
Treatment response and outcome of children with T-cell acute lymphoblastic leukemia expressing the gamma-delta T-cell receptor
Ching-Hon Pui, Deqing Pei, Cheng Cheng, Suzanne L. Tomchuck, Scarlett Evans, Hiroto Inaba, Sima Jeha, Susana C. Raimondi, John K. Choi, Paul G. Thomas, Mari Hashitate ...> ;Oncoimmunology. 2019 May 17
35 citations
Rapid cloning, expression, and functional characterization of paired αβ and γδ T-cell receptor chains from single-cell analysis
Xi-zhi J. Guo, Pradyot Dash, Matthew Calverley, Suzanne L. Tomchuck, Mari Hashitate Dallas, Paul G. Thomas> ;Molecular Therapy. Methods & Clinical Development. 2016 Jan 1
10 citations
Rapid memory T-cell reconstitution recapitulating CD45RA-depleted haploidentical transplant graft content in patients with hematologic malignancies.
B M Triplett, D R Shook, P Eldridge, Y Li, G Kang, M Dallas, C Hartford, A Srinivasan, W K Chan, D Suwannasaen, H Inaba, T E Merchant, C-H Pui, W Leung> ;Bone Marrow Transplantation. 2015 Jul 1
37 citations
Natural killer cell therapy in children with relapsed leukemia
Jeffrey E. Rubnitz, Hiroto Inaba, Guolian Kang, Kwan Gan, Christine Hartford, Brandon M. Triplett, Mari Hashitate Dallas, David Shook, Tanja A. Gruber, Ching-Hon Pui, ...> ;Pediatric Blood & Cancer. 2015 Aug 1
Rapid memory T-cell reconstitution recapitulating CD45RA-depleted haploidentical transplant graft content in patients with hematologic malignancies.
Triplett, B. M.,Shook, D. R.,Eldridge, P.,Li, Y.,Kang, G.,Dallas, M.,Hartford, C.,Srinivasan, A.,Chan, W. K.,Suwannasaen, D.,Inaba, H.,Merchant, T. E.,Pui, C. H.,Leung...> ;Bone Marrow Transplant.. 2015 Feb 11
76 citations
Gamma Delta T Cell Reconstitution Is Associated with Fewer Infections and Improved Event-Free Survival after Hematopoietic Stem Cell Transplantation for Pediatric Leuk...
Ross Perko, Guolian Kang, Anusha Sunkara, Wing Leung, Paul G. Thomas, Mari Hashitate Dallas> ;Biology of Blood and Marrow Transplantation. 2015 Jan 1
19 citations
Enhanced Cytotoxic Function of Natural Killer and CD3+CD56+ Cells in Cord Blood after Culture
Suzanne L. Tomchuck, Wing Leung, Mari Hashitate Dallas> ;Biology of Blood and Marrow Transplantation. 2015 Jan 1
10 citations
Phase I Study of the Safety and Pharmacokinetics of Plerixafor in Children Undergoing a Second Allogeneic Hematopoietic Stem Cell Transplantation for Relapsed or Refra...
Ashok Srinivasan, John C. Panetta, Shane J Cross, Asha Pillai, Brandon M. Triplett, David Shook, Mari Hashitate Dallas, Christine Hartford, Anusha Sunkara, Guolian Kan...> ;Biology of Blood and Marrow Transplantation. 2014 Aug 1
33 citations
Risk-adapted donor lymphocyte infusion based on chimerism and donor source in pediatric leukemia
Piya Rujkijyanont, Cynthia Morris, Guolian Kang, Kwan Gan, Christine Hartford, Brandon M. Triplett, Mari Hashitate Dallas, Ashok Srinivasan, David Shook, Asha Pillai, ...> ;Blood Cancer Journal. 2013 Aug 30
103 citations
Long-term outcome and evaluation of organ function in pediatric patients undergoing haploidentical and matched related hematopoietic cell transplantation for sickle ce...
Mari Hashitate Dallas, Brandon M. Triplett, David Shook, Christine Hartford, Ashok Srinivasan, Joseph Laver, Russell E. Ware, Wing Leung> ;Biology of Blood and Marrow Transplantation. 2013 May 1
5 citations
Successful allogeneic hematopoietic cell engraftment after a minimal conditioning regimen in children with relapsed or refractory solid tumors.
David Shook, Brandon M. Triplett, Ashok Srinivasan, Christine Hartford, Mari Hashitate Dallas, Asha Pillai, Joseph Laver, Wing Leung> ;Biology of Blood and Marrow Transplantation. 2013 Feb 1
6 citations
Effects of conditioning regimens and T-cell depletion in hematopoietic cell transplantation for primary immune deficiency
Brandon M. Triplett, Chong Wang, Jie Yang, Mari Hashitate Dallas, Christine Hartford, Vanessa Howard, Asha Pillai, David Shook, Ashok Srinivasan, Joseph Laver, Wing Leung> ;Biology of Blood and Marrow Transplantation. 2012 Dec 1
142 citations
Detectable minimal residual disease before hematopoietic cell transplantation is prognostic but does not preclude cure for children with very-high-risk leukemia
Wing Leung, Ching-Hon Pui, Elaine Coustan-Smith, Jie Yang, Deqing Pei, Kwan Gan, Ashok Srinivasan, Christine Hartford, Brandon M. Triplett, Mari Hashitate Dallas, Asha...> ;Blood. 2012 Jul 12
8 citations
Favorable preliminary results using TLI/ATG-based immunomodulatory conditioning for matched unrelated donor allogeneic hematopoietic stem cell transplantation in pedia...
Asha Pillai, Christine Hartford, Chong Wang, Deqing Pei, Jie Yang, Ashok Srinivasan, Brandon M. Triplett, Mari Hashitate Dallas, Wing Leung> ;Pediatric Transplantation. 2011 Sep 1
116 citations
High success rate of hematopoietic cell transplantation regardless of donor source in children with very high-risk leukemia
Wing Leung, Dario Campana, Jie Yang, Deqing Pei, Elaine Coustan-Smith, Kwan Gan, Jeffrey E. Rubnitz, John T. Sandlund, Raul C. Ribeiro, Ashok Srinivasan, Christine Har...> ;Blood. 2011 Jul 14
15 citations
Notch target Hes5 ensures appropriate Notch induced T- versus B-cell choices in the thymus.
Barbara Varnum-Finney, Mari H. Dallas, Keizo Kato, Irwin D. Bernstein> ;Blood. 2008 Mar 1
42 citations
Enhanced T-cell reconstitution by hematopoietic progenitors expanded ex vivo using the Notch ligand Delta1.
Mari H. Dallas, Barbara Varnum-Finney, Paul J. Martin, Irwin D. Bernstein> ;Blood. 2006 Nov 16
93 citations
Density of the Notch ligand Delta1 determines generation of B and T cell precursors from hematopoietic stem cells.
Mari H. Dallas, Barbara Varnum-Finney, Colleen Delaney, Keizo Kato, Irwin D. Bernstein> ;The Journal of Experimental Medicine. 2005 May 2
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Hospital Affiliations

UH Rainbow Babies and Childrens HospitalCleveland, Ohio