RobertBruceMontgomeryMD

Oncology • Seattle, WA

Professor, Medicine, University of Washington School of Medicine

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Office
1959 Ne Pacific St
Box 356158
Seattle, WA 98195
Phone+1 206-598-0860
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Clinical Expertise

General medical oncology, Hematologic oncology, Urethral cancer

Education & Training

University of WashingtonFellowship, Hematology and Medical Oncology, 1990 - 1993
Brigham and Women's HospitalResidency, Internal Medicine, 1987 - 1990
Duke University School of MedicineClass of 1987

Certifications & Licensure

WA State Medical License 1990 - 2025

Clinical Trials

Neoadjuvant Estradiol or Androgen Deprivation in Clinically Localized Prostate Cancer Start of enrollment: 2005 Mar 01
Completed
Phase 2
Collecting and Studying Blood and Tissue Samples From Patients With Locally Recurrent or Metastatic Prostate or Bladder/Urothelial Cancer Start of enrollment: 2009 Aug 01
Recruiting
Abiraterone Acetate in Treating Patients With Metastatic Hormone-Resistant Prostate Cancer Start of enrollment: 2012 Dec 01
Completed
Phase 2
Abiraterone Acetate and Prednisone With or Without Veliparib in Treating Patients With Metastatic Castration-Resistant Prostate Cancer Start of enrollment: 2012 Mar 30
Completed
Phase 2
Degarelix Acetate Before and During Radiation Therapy in Treating Patients With Prostate Cancer Start of enrollment: 2013 May 01
Completed
Not Applicable
Sirolimus, Cisplatin, and Gemcitabine Hydrochloride in Treating Patients With Bladder Cancer Start of enrollment: 2013 Oct 01
Completed
Phase 1, Phase 2
High Dose Testosterone for ATM, CDK12 or CHEK2 Altered Prostate Cancers Start of enrollment: 2021 Aug 31
Recruiting
Phase 2
Roles: Contact, Principal Investigator
A Single-Arm Phase II Study of Neoadjuvant Intensified Androgen Deprivation (Leuprolide and Abiraterone Acetate) in Combination With AKT Inhibition (Capivasertib) for High-Risk Localized Prostate Cancer With PTEN Loss Start of enrollment: 2024 Apr 01
Not yet recruiting
Phase 2
Roles: Contact
Carboplatin or Olaparib for BRcA Deficient Prostate Cancer Start of enrollment: 2019 Oct 01
Recruiting
Phase 2
Roles: Contact, Principal Investigator
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Publications & Presentations

PubMed

A combinatorial genetic strategy for exploring complex genotype-phenotype associations in cancer.
Shan Li, Alicia Wong, Huiyun Sun, Vipul Bhatia, Gerardo Javier, Sujata Jana, Qian Wu, Robert B Montgomery, Jonathan L Wright, Hung-Ming Lam, Andrew C Hsieh, Bishoy M F...> ;Nature Genetics. 2024 Mar 1
ASSESSMENT OF CELL SURFACE TARGETS IN METASTATIC PROSTATE CANCER: EXPRESSION LANDSCAPE AND MOLECULAR CORRELATES.
Ajkunic, A., Sayar, E., Roudier, M., Patel, R., Coleman, I., De Sarkar, N., Hanratty, B., Adil, M., Zhao, J., Zaidi, S., True, L., Sperger, J., Cheng, H., Yu, E., Mont...> ;Research Square. 2023 Dec 19
1 citations
On-Site Nurse-Led Cancer Genetics Program Increases Cancer Genetic Testing Completion in Black Veterans.
Jeffrey W Shevach, Lisa B Aiello, Julie A Lynch, Jeffrey Petersen, Lori Hoffman-Hogg, Deborah Hartzfeld, Margaret Lundquist, Michael J Kelley, Maren T Scheuner, Robert...> ;JCO Oncology Practice. 2023 Aug 1
9 citations
Nucleosome Patterns in Circulating Tumor DNA Reveal Transcriptional Regulation of Advanced Prostate Cancer Phenotypes.
Navonil De Sarkar, Robert D Patton, Anna-Lisa Doebley, Brian Hanratty, Mohamed Adil, Adam J Kreitzman, Jay F Sarthy, Minjeong Ko, Sandipan Brahma, Michael P Meers, Der...> ;Cancer Discovery. 2023 Mar 1
1 citations
Allogeneic stem cell transplantation in patients with a prior history of prostate cancer.
Raffaele Palmieri, Robert B Montgomery, Kristine Doney> ;Annals of Hematology. 2023 Feb 1
2 citations
Phase II trial of CV301 vaccine combined with atezolizumab in advanced urothelial carcinoma.
Guru P Sonpavde, Benjamin Louis Maughan, Bradley Alexander McGregor, Xiao X Wei, Kerry L Kilbridge, Richard J Lee, Evan Y Yu, Michael Thomas Schweizer, Robert B Montgo...> ;Cancer Immunology, Immunotherapy. 2023 Mar 1
6 citations
Association of the Time to Immune Checkpoint Inhibitor (ICI) Initiation and Outcomes With Second Line ICI in Patients With Advanced Urothelial Carcinoma.
Rafee Talukder, Dimitrios Makrakis, Genevieve Ihsiu Lin, Leonidas N Diamantopoulos, Scott Dawsey, Shilpa Gupta, Lucia Carril-Ajuria, Daniel Castellano, Ivan de Kouchko...> ;Clinical Genitourinary Cancer. 2022 Dec 1
8 citations
Association Between Sites of Metastasis and Outcomes With Immune Checkpoint Inhibitors in Advanced Urothelial Carcinoma.
Dimitrios Makrakis, Rafee Talukder, Genevieve Ihsiu Lin, Leonidas N Diamantopoulos, Scott Dawsey, Shilpa Gupta, Lucia Carril-Ajuria, Daniel Castellano, Ivan de Kouchko...> ;Clinical Genitourinary Cancer. 2022 Oct 1
18 citations
Effect of Androgen Suppression on Clinical Outcomes in Hospitalized Men With COVID-19: The HITCH Randomized Clinical Trial.
Nicholas G Nickols, Zhibao Mi, Ellen DeMatt, Kousick Biswas, Christina E Clise, John T Huggins, Spyridoula Maraka, Elena Ambrogini, Mehdi S Mirsaeidi, Ellis R Levin, D...> ;JAMA Network Open. 2022 Apr 1
11 citations
Genomic attributes of homology-directed DNA repair deficiency in metastatic prostate cancer.
Navonil De Sarkar, Sayan Dasgupta, Payel Chatterjee, Ilsa Coleman, Gavin Ha, Lisa S Ang, Emily A Kohlbrenner, Sander B Frank, Talina A Nunez, Stephen J Salipante, Eva ...> ;JCI Insight. 2021 Dec 8
15 citations
A phase 1 study to assess the safety, pharmacokinetics, and anti-tumor activity of the androgen receptor n-terminal domain inhibitor epi-506 in patients with metastati...
Corinne Maurice-Dror, Ronan Le Moigne, Ulka N. Vaishampayan, Robert B. Montgomery, Michael S. Gordon, Nan Hyung Hong, Leah DiMascio, Frank Perabo, Kim N. Chi> ;Investigational New Drugs. 2021 Nov 29
2 citations
A Prospective Study of a Resorbable Intravesical Fiducial Marker for Bladder Cancer Radiation Therapy.
Matthew D Greer, Stephanie K Schaub, Stephen R Bowen, Jay J Liao, Kenneth Russell, Jonathan J Chen, Emily S Weg, Juergen Meyer, Tristan Alving, George R Schade, John L...> ;Advances in Radiation Oncology. 2021 Nov 21
12 citations
Response to Neoadjuvant Chemotherapy and Survival in Micropapillary Urothelial Carcinoma: Data From a Tertiary Referral Center and the Surveillance, Epidemiology, and ...
Leonidas Nikolaos Diamantopoulos, Sarah K. Holt, Ali Raza Khaki, Rishi R. Sekar, Adam J. Gadzinski, Yaw A. Nyame, Funda Vakar-Lopez, Maria S. Tretiakova, Sarah P. Psut...> ;Clinical Genitourinary Cancer. 2021 Apr 1
2 citations
Patterns and timing of perioperative blood transfusion and association with outcomes after radical cystectomy.
Leonidas Nikolaos Diamantopoulos, Rishi R. Sekar, Sarah K. Holt, Ali Raza Khaki, Natalie J. Miller, Adam J. Gadzinski, Yaw A. Nyame, Funda Vakar-Lopez, Maria S. Tretia...> ;Urologic Oncology. 2021 Feb 4
13 citations
Plasmacytoid urothelial carcinoma: response to chemotherapy and oncologic outcomes.
Leonidas Nikolaos Diamantopoulos, Ali Raza Khaki, Petros Grivas, John L. Gore, George R. Schade, Andrew C. Hsieh, John K. Lee, Todd Yezefski, Evan Y. Yu, Michael T. Sc...> ;Bladder Cancer. 2020 Mar 28
9 citations
Downstaging of Muscle-Invasive Bladder Cancer Using Neoadjuvant Gemcitabine and Cisplatin or Dose-Dense Methotrexate, Vinblastine, Doxorubicin, and Cisplatin as Single...
Andrew T. Ruplin, Anne M.Z. Spengler, Robert B. Montgomery, Jonathan L. Wright> ;Clinical Genitourinary Cancer. 2020 Feb 22
29 citations
Genomic distinctions between metastatic lower and upper tract urothelial carcinoma revealed through rapid autopsy
Brian Winters, Navonil De Sarkar, Sonali Arora, Hamid Bolouri, Sujata Jana, Funda Vakar-Lopez, Heather H. Cheng, Michael T. Schweizer, Evan Y. Yu, Petros Grivas, John ...> ;JCI Insight. 2019 Jul 11
685 citations
Genomic correlates of clinical outcome in advanced prostate cancer.
Wassim Abida, Joanna Cyrta, Glenn Heller, Davide Prandi, Joshua Armenia, Ilsa Coleman, Marcin Cieslik, Matteo Benelli, Dan R. Robinson, Eliezer M. Van Allen, Andrea Sb...> ;Proceedings of the National Academy of Sciences of the United States of America. 2019 Jun 4
8 citations
Efficacy of Therapies After Galeterone in Patients With Castration-resistant Prostate Cancer.
Rana R. McKay, Lillian Werner, Matthew Fiorillo, Jennifer Roberts, Elisabeth I. Heath, Glenn J. Bubley, Robert B. Montgomery, Mary-Ellen Taplin> ;Clinical Genitourinary Cancer. 2017 Aug 1
Neoadjuvant Enzalutamide Prior to Prostatectomy.
Montgomery B, Tretiakova MS, Joshua AM, Gleave ME, Fleshner N, Bubley GJ, Mostaghel EA, Chi KN, Lin DW, Sanda M, Novotny W, Wu K, Kantoff PW, Marck BT, Plymate S, Balk...> ;Clin Cancer Res. 2016 Nov 09
67 citations
Mismatch repair deficiency may be common in ductal adenocarcinoma of the prostate.
Michael T. Schweizer, Heather H. Cheng, Maria S. Tretiakova, Funda Vakar-Lopez, Nola Klemfuss, Eric Q. Konnick, Elahe A. Mostaghel, Peter S. Nelson, Evan Y. Yu, Bruce ...> ;Oncotarget. 2016 Oct 15
27 citations
A Phase II Trial of Abiraterone Combined with Dutasteride for Men with Metastatic Castration-Resistant Prostate Cancer.
Rana R. McKay, Lillian Werner, Elahe A. Mostaghel, Rosina T. Lis, Olga Voznesensky, Zhenwei Zhang, Brett T. Marck, Alvin M. Matsumoto, Liran Domachevsky, Katherine Zuk...> ;Clinical Cancer Research. 2017 Feb 15
21 citations
A pilot study of clinical targeted next generation sequencing for prostate cancer: consequences for treatment and genetic counseling
Heather H. Cheng, Nola Klemfuss, Bruce Montgomery, Celestia S. Higano, Michael T. Schweizer, Elahe A. Mostaghel, Lisa McFerrin, Evan Y. Yu, Peter S. Nelson, Colin C. P...> ;The Prostate. 2016 Oct 1
1018 citations
Inherited DNA-Repair Gene Mutations in Men with Metastatic Prostate Cancer
Colin C. Pritchard, Joaquin Mateo, Michael Walsh, Navonil De Sarkar, Wassim Abida, Himisha Beltran, Andrea Garofalo, Roman Gulati, Suzanne Carreira, Rosalind A. Eeles,...> ;The New England Journal of Medicine. 2016 Jul 6
21 citations
Low Incidence of Corticosteroid-associated Adverse Events on Long-term Exposure to Low-dose Prednisone Given with Abiraterone Acetate to Patients with Metastatic Castr...
Karim Fizazi, Kim N. Chi, Johann S. de Bono, Leonard G. Gomella, Kurt Miller, Dana E. Rathkopf, Charles J. Ryan, Howard I. Scher, Neal D. Shore, Peter De Porre, Anil L...> ;European Urology. 2016 Sep 1
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