AdamJosephLambleMD

PubMed

• IFN-γ and CD38 in AML: a T-cell engagement made in heaven?
  Rachel E Rau, Adam J Lamble> ;Blood. 2024 Apr 18
• Drug-regulated CD33-targeted CAR T cells control AML using clinically optimized rapamycin dosing.
  Jacob Appelbaum, April E Price, Kaori Oda, Joy Zhang, Wai-Hang Leung, Giacomo Tampella, Dong Xia, Pauline Pl So, Sarah K Hilton, Claudya Evandy, Semanti Sarkar, Unja M...> ;The Journal of Clinical Investigation. 2024 Mar 19
• Nivolumab Plus 5-Azacitidine in Pediatric Relapsed/Refractory Acute Myeloid Leukemia (AML): Phase I/II Trial Results from the Therapeutic Advances in Childhood Leukemi...
  Verma, A., Chi, Y., Malvar, J., Lamble, A., Chaudhury, S., Agarwal, A., Li, H., Liang, G., Leong, R., Brown, P., Kaplan, J., Schafer, E., Slone, T., Pauly, M., Chang, ...> ;Cancers. 2024 Jan 24
• 1 citations
  INSPIRED Symposium Part 4A: Access to CAR T Cell Therapy in Unique Populations with B Cell Acute Lymphoblastic Leukemia.
  Lena E Winestone, Deepa Bhojwani, Sara Ghorashian, Lori Muffly, Allison Barz Leahy, Karen Chao, Angela Steineck, Claudia Rössig, Adam Lamble, Shannon L Maude, Regina M...> ;Transplantation and Cellular Therapy. 2024 Jan 1
• 3 citations
  INSPIRED Symposium Part 2: Prevention and Management of Relapse Following Chimeric Antigen Receptor T Cell Therapy for B Cell Acute Lymphoblastic Leukemia.
  Adam J Lamble, Amy Moskop, Michael A Pulsipher, Shannon L Maude, Corinne Summers, Colleen Annesley, André Baruchel, Lia Gore, Persis Amrolia, Nirali Shah> ;Transplantation and Cellular Therapy. 2023 Nov 1
• 3 citations
  Blastic plasmacytoid dendritic cell neoplasm: a comprehensive review in pediatrics, adolescents, and young adults (AYA) and an update of novel therapies.
  Branko Cuglievan, Jeremy Connors, Jiasen He, Sajad Khazal, Sireesha Yedururi, Julia Dai, Sofia Garces, Andres E Quesada, Michael Roth, Miriam Garcia, David McCall, Amb...> ;Leukemia. 2023 Sep 1
• 1 citations
  Introduction to the Reports from the Insights in Pediatric CAR T-cell Immunotherapy: Recent Advances and Future Directions (INSPIRED) Symposium.
  Liora Schultz, Elad Jacoby, Adam J Lamble, Shannon L Maude, Amy Moskop, Regina M Myers, Michael A Pulsipher, Nirali N Shah, McNerney, K.> ;Transplantation and Cellular Therapy. 2023 Oct 1
• CD43-positive, EWSR1::FLI1 -rearranged Soft Tissue Sarcoma in a Pediatric Patient With History of B-Cell Acute Lymphoblastic Leukemia.
  Timothy J D Ohlsen, Erin R Rudzinski, Sandra D Bohling, Yajuan J Liu, Ezekiel J Maloney, Antoinette W Lindberg, Catherine M Albert, Adam J Lamble, Mallory R Taylor> ;Journal of Pediatric Hematology/oncology. 2023 Jul 1
• 4 citations
  Access to Chimeric Antigen Receptor T Cell Clinical Trials in Underrepresented Populations: A Multicenter Cohort Study of Pediatric and Young Adult Acute Lymphobastic ...
  Anurekha G Hall, Lena E Winestone, Erin M Sullivan, Qian Wu, Adam J Lamble, Mark C Walters, Paibel Aguayo-Hiraldo, Lourdes Baez Conde, Tumaini R Coker, Dana Dornsife, ...> ;Transplantation and Cellular Therapy. 2023 Jun 1
• 48 citations
  Preinfusion factors impacting relapse immunophenotype following CD19 CAR T cells.
  Adam J Lamble, Regina M Myers, Agne Taraseviciute, Samuel John, Bonnie Yates, Seth M Steinberg, Jennifer Sheppard, Alexandra E Kovach, Brent Wood, Michael J Borowitz, ...> ;Blood Advances. 2023 Feb 28
• 1 citations
  Plasticity of lineage switch in B-ALL allows for successful rechallenge with CD19-directed immunotherapy.
  Brittany M Lee, Corinne Summers, Karen M Chisholm, Sandra D Bohling, Kasey J Leger, Rebecca Gardner, Colleen Annesley, Adam J Lamble> ;Blood Advances. 2023 Jun 27
• 4 citations
  CREBBP alterations are associated with a poor prognosis in de novo AML.
  Adam J Lamble, Kohei Hagiwara, Robert B Gerbing, Jenny L Smith, Pandurang Kolekar, Rhonda E Ries, Edward A Kolb, Todd A Alonzo, Xiaotu Ma, Soheil Meshinchi> ;Blood. 2023 Apr 27
• 7 citations
  Low rate of subsequent malignant neoplasms after CD19 CAR T-cell therapy.
  Emily M Hsieh, Regina M Myers, Bonnie Yates, Colleen Annesley, Samuel John, Agne Taraseviciute, Seth M Steinberg, Jennifer Sheppard, Perry Chung, Lee Chen, Daniel W Le...> ;Blood Advances. 2022 Sep 13
• 7 citations
  Bryostatin Activates CAR T-Cell Antigen-Non-Specific Killing (CTAK), and CAR-T NK-Like Killing for Pre-B ALL, While Blocking Cytolysis of a Burkitt Lymphoma Cell Line.
  Lingyan Wang, Yue Zhang, Eden Anderson, Adam Lamble, Rimas J Orentas> ;Frontiers in Immunology. 2022 Jan 1
• 19 citations
  CD123 Expression Is Associated With High-Risk Disease Characteristics in Childhood Acute Myeloid Leukemia: A Report From the Children's Oncology Group.
  Adam J. Lamble, Lisa Eidenschink Brodersen, Todd A. Alonzo, Jim Wang, Laura Pardo, Lillian Sung, Todd Cooper, E. Anders Kolb, Richard Aplenc, Sarah K. Tasian, Michael ...> ;Journal of Clinical Oncology. 2021 Dec 2
• 86 citations
  Blinatumomab Nonresponse and High-Disease Burden Are Associated With Inferior Outcomes After CD19-CAR for B-ALL.
  Regina M. Myers, Agne Taraseviciute, Seth M. Steinberg, Adam J. Lamble, Jennifer Sheppard, Bonnie Yates, Alexandra E. Kovach, Brent L. Wood, Michael J. Borowitz, Marya...> ;Journal of Clinical Oncology. 2021 Nov 12
• 1 citations
  Chemotherapy roadmaps in pediatric oncology: A digital electronic medical record integrated solution.
  Mary T Field, Adam J. Lamble, Susan Holtzclaw, Sarah A Tucker, Tyler G. Ketterl> ;Journal of Oncology Pharmacy Practice. 2021 Sep 24
• 10 citations
  Pediatric hodgkin lymphoma, version 3.2021
  Jamie E. Flerlage, Susan M. Hiniker, Saro H. Armenian, Ellen C Benya, Adam J. Bobbey, Vivian Y. Chang, Stacy Cooper, Don W. Coulter, Branko Cuglievan, Bradford S. Hopp...> ;Journal of the National Comprehensive Cancer Network. 2021 Jun 30
• 41 citations
  CEBPA-bZip mutations are associated with favorable prognosis in de novo AML: a report from the Children's Oncology Group.
  Katherine Tarlock, Adam J. Lamble, Yi-Cheng Wang, Robert B. Gerbing, Rhonda E. Ries, Michael R. Loken, Lisa Eidenschink Brodersen, Laura Pardo, Amanda R. Leonti, Jenny...> ;Blood. 2021 Sep 30
• 87 citations
  Distinct genetic pathways define pre-malignant versus compensatory clonal hematopoiesis in Shwachman-Diamond syndrome.
  Alyssa L. Kennedy, Kasiani C. Myers, James Bowman, Christopher J. Gibson, Nicholas D. Camarda, Elissa Furutani, Gwen M. Muscato, Robert H. Klein, Kaitlyn Ballotti, Sha...> ;Nature Communications. 2021 Feb 26
• 4 citations
  CAR T cells for other pediatric non-B-cell hematologic malignancies.
  Adam J. Lamble, Rebecca Gardner> ;Hematology. American Society of Hematology. Education Program. 2020 Dec 4
• 18 citations
  Concomitant use of a dual Src/ABL kinase inhibitor eliminates the in vitro efficacy of blinatumomab against Ph+ ALL
  Jessica Leonard, Yoko Kosaka, Pavani Malla, Dorian LaTocha, Adam J. Lamble, Brandon Hayes-Lattin, Kaelan Byrd, Brian J. Druker, Jeffrey W. Tyner, Bill H. Chang, Evan F...> ;Blood. 2021 Feb 18
• 44 citations
  Reversible suppression of T cell function in the bone marrow microenvironment of acute myeloid leukemia.
  , , , , , , , , , , , , , , , , , , , , > ;Proceedings of the National Academy of Sciences of the United States of America. 2020 Jun 23
• Opportunities for immunotherapy in childhood acute myeloid leukemia.
  Adam J Lamble, Sarah K Tasian> ;Hematology. American Society of Hematology. Education Program. 2019 Dec 6
• 15 citations
  Opportunities for immunotherapy in childhood acute myeloid leukemia.
  Adam J Lamble, Sarah K Tasian> ;Blood Advances. 2019 Nov 26
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Journal Articles

• Research Paper Integrated Functional and Mass Spectrometry-Based Flow Cytometric Phenotyping to Describe the Immune Microenvironment in Acute Myeloid Leukemia  
  Adam Lamble, MD, ScienceDirect

Abstracts/Posters

• Novel CD19t T-Antigen Presenting Cells Expand CD19 CAR T Cells In Vivo
  Adam J. Lamble, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019