AdrianGeroldSacherMDMMSc

PubMed

• 3 citations
  The dawn of a new era, adjuvant EGFR inhibition in resected non-small cell lung cancer.
  Barbara Melosky, Parneet Cheema, Rosalyn A. Juergens, Natasha B. Leighl, Geoffrey Liu, Paul Wheatley-Price, Adrian G. Sacher, Stephanie Snow, Ming-Sound Tsao, Deanna M...> ;Therapeutic Advances in Medical Oncology. 2021 Nov 15
• 4 citations
  Concurrent chemoradiation with or without durvalumab in elderly patients with unresectable stage 3 non-small cell lung cancer: safety and efficacy
  S. Lau, Malcolm Ryan, Jessica Weiss, Aline Fusco Fares, Miguel Garcia, S. Schmid, Shelley Kuang, Deirdre Kelly, Ming-Sound Tsao, Penelope A. Bradbury, B.C. John Cho, A...> ;JTO Clinical and Research Reports. 2021 Nov 1
• 4 citations
  Chemical Genetics Screen Identifies COPB2 Tool Compounds That Alters ER Stress Response and Induces RTK Dysregulation in Lung Cancer Cells.
  Punit Saraon, Jamie Snider, Wiebke Schormann, Ankit Rai, Nikolina Radulovich, María Sánchez-Osuna, Jasmin Coulombe-Huntington, Caroline Huard, Mohammed Mohammed, Evely...> ;Journal of Molecular Biology. 2021 Oct 15
• 1 citations
  Longitudinal Assessment of Health Utility Scores, Symptoms and Toxicities in Patients with Small Cell Lung Cancer Using Real World Data.
  Nathan Kuehne, Katrina Hueniken, Maria Xu, Sharara Shakik, Ali Vedadi, Dixon Pinto, M. Catherine Brown, Penelope A. Bradbury, Frances A. Shepherd, Adrian G. Sacher, Na...> ;Clinical Lung Cancer. 2021 Sep 25
• 5 citations
  Predictive radiomics signature for treatment response to nivolumab in patients with advanced renal cell carcinoma.
  Eoghan Ruadh Malone, Hao-Wen Sim, Audrius Stundzia, Sacha Pierre, Ur Metser, Martin E. O’Malley, Adrian G. Sacher, Srikala S. Sridhar, Aaron R. Hansen> ;Canadian Urological Association Journal = Journal De L'association Des Urologues Du Canada. 2021 Sep 24
• 26 citations
  Prevalence and Heterogeneity of PD-L1 Expression by 22C3 Assay in Routine Population-Based and Reflexive Clinical Testing in Lung Cancer.
  David M. Hwang, Tahani Albaqer, Rex C. Santiago, Jessica Weiss, Jeffrey Tanguay, Michael Cabanero, Yuki Leung, Prodipto Pal, Zanobia Khan, S. Lau, Adrian G. Sacher, Em...> ;Journal of Thoracic Oncology. 2021 Sep 1
• 7 citations
  Natural Killer Cells and Type 1 Innate Lymphoid Cells in Hepatocellular Carcinoma: Current Knowledge and Future Perspectives.
  Nicolas Jacquelot, Cyril Seillet, Fernando Souza-Fonseca-Guimaraes, Adrian G. Sacher, Gabrielle T. Belz, Pamela S. Ohashi> ;International Journal of Molecular Sciences. 2021 Aug 22
• 2 citations
  Treatment Patterns and Outcomes of Patients With Advanced Pleural Mesothelioma at an Academic Referral Centre.
  S. Schmid, Luna Zhan, Kristen Dietrich, K. Khan, Maisha Chowdhury, Michael A. Herman, Devalben Patel, Fatemeh Zaeimi, Natasha B. Leighl, Adrian G. Sacher, Ronald Feld,...> ;Clinical Lung Cancer. 2021 Aug 10
• The financial impact of cancer care on renal cancer patients.
  Doreen A. Ezeife, Brendon Josh Morganstein, Steven Yip, Malcolm Ryan, J. Law, Amy Yimin Guan, Lisa W. Le, Aaron R. Hansen, Adrian G. Sacher, Georg A. Bjarnason, Mark D...> ;The Canadian Journal of Urology. 2021 Aug 1
• 6 citations
  Clinicopathologic factors that influence prognosis and survival outcomes in men with metastatic castration-resistant prostate cancer treated with Radium-223
  Esmail Mutahar Al-Ezzi, Husam Alqaisi, Marco A. J. Iafolla, Lisa Wang, Srikala S. Sridhar, Adrian G. Sacher, Nazanin Fallah-Rad, Di Maria Jiang, Geoffrey Alan Watson, ...> ;Cancer Medicine. 2021 Jul 13
• 34 citations
  The rapidly evolving landscape of novel targeted therapies in advanced non-small cell lung cancer.
  Barbara Melosky, Paul Wheatley-Price, Rosalyn A. Juergens, Adrian G. Sacher, Natasha B. Leighl, Ming-Sound Tsao, Parneet Cheema, Stephanie Snow, Geoffrey Liu, Paul B. ...> ;Lung Cancer. 2021 Jun 5
• 564 citations
  Sotorasib for Lung Cancers with KRAS p.G12C Mutation.
  Ferdinandos Skoulidis, Bob T. Li, Grace K. Dy, Timothy J. Price, Gerald Steven Falchook, Jürgen Wolf, Antoine Italiano, Martin Schuler, Hossein Borghaei, Fabrice Barle...> ;The New England Journal of Medicine. 2021 Jun 4
• 5 citations
  Durability of CNS disease control in NSCLC patients with brain metastases treated with immune checkpoint inhibitors plus cranial radiotherapy.
  S. Lau, Christopher Poletes, Lisa W. Le, Kate M. Mackay, Aline Fusco Fares, Penelope A. Bradbury, Frances A. Shepherd, Ming-Sound Tsao, Natasha B. Leighl, Geoffrey Liu...> ;Lung Cancer. 2021 Apr 8
• 7 citations
  Systemic Inflammatory Markers of Survival in Epidermal Growth Factor-Mutated Non-Small-Cell Lung Cancer: Single-Institution Analysis, Systematic Review, and Meta-analy...
  Sze Wah Samuel Chan, Elliot Charles Smith, Reenika Aggarwal, Karmugi Balaratnam, RuiQi Chen, Katrina Hueniken, Rouhi Fazelzad, Jessica Weiss, Shirley Xue Jiang, France...> ;Clinical Lung Cancer. 2021 Jan 10
• 41 citations
  Subtypes of EGFR- and HER2-Mutant Metastatic NSCLC Influence Response to Immune Checkpoint Inhibitors.
  S. Lau, Aline Fusco Fares, Lisa W. Le, Kate M. Mackay, Spencer Soberano, Sze Wah Chan, Elliot Charles Smith, Malcolm Ryan, Ming-Sound Tsao, Penelope A. Bradbury, Prodi...> ;Clinical Lung Cancer. 2021 Jan 7
• 4 citations
  Genomic characterization of non-schistosomiasis-related squamous cell carcinoma of the urinary bladder: A retrospective exploratory study.
  Esmail Mutahar Al-Ezzi, Zachary William Neil Veitch, Samer Salah, Theodorus H. van der Kwast, Tracy Stockley, Shamini Selvarajah, Tong Zhang, Srikala S. Sridhar, Adria...> ;Plos One. 2021 Jan 1
• 45 citations
  Durvalumab therapy following chemoradiation compared with a historical cohort treated with chemoradiation alone in patients with stage III non-small cell lung cancer: ...
  Antoine Desilets, Félix Blanc-Durand, S. Lau, Taiki Hakozaki, Rui Kitadai, Julie Malo, Wiam Belkaid, Corentin Richard, Meriem Messaoudene, Lena Cvetkovic, Suzanne Kaza...> ;European Journal of Cancer. 2021 Jan 1
• 25 citations
  Tobacco exposure and immunotherapy response in PD-L1 positive lung cancer patients.
  J. Li, Khizar Karim, Mike Sung, Lisa W. Le, S. Lau, Adrian G. Sacher, Natasha B. Leighl> ;Lung Cancer. 2020 Nov 4
• 587 citations
  KRASG12C Inhibition with Sotorasib in Advanced Solid Tumors.
  , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , > ;The New England Journal of Medicine. 2020 Sep 20
• 5 citations
  The impact of symptoms and comorbidity on health utility scores and health-related quality of life in small cell lung cancer using real world data.
  Ali Vedadi, Sharara Shakik, M. Catherine Brown, Benjamin H. Lok, Frances A. Shepherd, Natasha B. Leighl, Adrian G. Sacher, Penelope A. Bradbury, Wei Xu, Geoffrey Liu, ...> ;Quality of Life Research. 2021 Feb 1
• 16 citations
  Cytotoxic CD4+ T Cells in Bladder Cancer-A New License to Kill.
  Adrian G. Sacher, Michael St. Paul, Christopher J. Paige, Pamela S. Ohashi> ;Cancer Cell. 2020 Jul 13
• 2 citations
  EGFR-mutated lung adenocarcinomas from patients who progressed on EGFR-inhibitors show high engraftment rates in xenograft models
  Sebastiao N. Martins-Filho, Jessica Weiss, Nhu-An Pham, Quan Li, Michael Cabanero, Aline Fusco Fares, Erin L. Stewart, Ruoshi Shi, Devalben Patel, Prodipto Pal, Judy M...> ;Lung Cancer. 2020 Jul 1
• 12 citations
  ALK-rearranged lung adenocarcinoma transformation into high-grade large cell neuroendocrine carcinoma: Clinical and molecular description of two cases.
  Aline Fusco Fares, Benjamin H. Lok, Tong Zhang, Michael Cabanero, S. Lau, Tracy Stockley, Devalben Patel, Penelope A. Bradbury, Adrian G. Sacher, Kazuhiro Yasufuku, Ba...> ;Lung Cancer. 2020 Jun 9
• 21 citations
  BRAF V600E mutation and MET amplification as resistance pathways of the second-generation anaplastic lymphoma kinase (ALK) inhibitor alectinib in lung cancer.
  Ruoshi Shi, Sebastiao N. Martins Filho, Ming Li, Aline Fusco Fares, Jessica Weiss, Nhu-An Pham, Olga Ludkovski, Vibha Raghavan, Quan Li, Deepti Ravi, Michael Cabanero,...> ;Lung Cancer. 2020 May 21
• 5 citations
  Early Detection of Multiple Resistance Mechanisms by ctDNA Profiling in a Patient With EGFR-mutant Lung Adenocarcinoma Treated With Osimertinib.
  S. Schmid, Erin L. Stewart, Sebastiao N. Martins-Filho, Michael Cabanero, Ao Wang, Hua Bao, Xue Wu, Deval Patel, Zhuo Chen, J. Law, Penelope A. Bradbury, Frances A. Sh...> ;Clinical Lung Cancer. 2020 Apr 9
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Journal Articles

• KRASG12C Inhibition with Sotorasib in Advanced Solid Tumors  
  David S Hong, Marwan G Fakih, Gregory A Durm, Geoffrey I Shapiro, Gerald S Falchook, Adrian Sacher, Crystal S Denlinger, John C Krauss, Andrew L Coveler, Suresh S Rama..., The New England Journal of Medicine