AzraRazaMD

PubMed

• scRNAseq and High-Throughput Spatial Analysis of Tumor and Normal Microenvironment in Solid Tumors Reveal a Possible Origin of Circulating Tumor Hybrid Cells.
  Abdullah Mahmood Ali, Azra Raza> ;Cancers. 2024 Apr 8
• mutations are associated with a response to alvocidib and 5-azacytidine combination in myelodysplastic neoplasms.
  Vladimir Riabov, Qingyu Xu, Nanni Schmitt, Alexander Streuer, Guo Ge, Lyndsey Bolanos, Mark Wunderlich, Johann-Christoph Jann, Alina Wein, Eva Altrock, Marie Demmerle,...> ;Haematologica. 2023 Nov 2
• Circulating cancer giant cells with unique characteristics frequently found in patients with myelodysplastic syndromes (MDS).
  Abdullah Mahmood Ali, Fatima BenMohamed, Alessandra Decina, Sanjay Mukherjee, Shelley Levi, Laura Nalleli Garrido Castillo, Davide Bréchot, Joseph Jurcic, Azra Raza, P...> ;Medical Oncology. 2023 Jun 14
• 8 citations
  Mutation in SF3B1 gene promotes formation of polyploid giant cells in Leukemia cells.
  Sanjay Mukherjee, Abdullah Mahmood Ali, Vundavalli V Murty, Azra Raza> ;Medical Oncology. 2022 Apr 28
• 11 citations
  Subversion of Serotonin Receptor Signaling in Osteoblasts by Kynurenine Drives Acute Myeloid Leukemia.
  Marta Galán-Díez, Florence Borot, Abdullah Mahmood Ali, Junfei Zhao, Eva Gil-Iturbe, Xiaochuan Shan, Na Luo, Yongfeng Liu, Xi-Ping Huang, Brygida Bisikirska, Rossella ...> ;Cancer Discovery. 2022 Apr 1
• 22 citations
  SF3B1 mutant-induced missplicing of MAP3K7 causes anemia in myelodysplastic syndromes.
  Yen K Lieu, Zhaoqi Liu, Abdullah M Ali, Xin Wei, Alex Penson, Jian Zhang, Xiuli An, Raul Rabadan, Azra Raza, James L Manley, Siddhartha Mukherjee> ;Proceedings of the National Academy of Sciences of the United States of America. 2022 Jan 4
• 25 citations
  Comprehensive phenotyping of erythropoiesis in human bone marrow: Evaluation of normal and ineffective erythropoiesis.
  Hongxia Yan, Abdullah Mahmood Ali, Lionel Blanc, Anupama Narla, Joseph M. Lane, Erjing Gao, Julien Papoin, John Hale, Christopher D. Hillyer, Naomi Taylor, Patrick G. ...> ;American Journal of Hematology. 2021 Sep 1
• 61 citations
  Imetelstat Achieves Meaningful and Durable Transfusion Independence in High Transfusion-Burden Patients With Lower-Risk Myelodysplastic Syndromes in a Phase II Study.
  David P. Steensma, Pierre Fenaux, Koen Van Eygen, Azra Raza, Valeria Santini, Ulrich Germing, Patricia Font, María Díez-Campelo, Sylvain Thepot, Edo Vellenga, Mrinal M...> ;Journal of Clinical Oncology. 2021 Jan 1
• 11 citations
  Rewriting the rules for care of MDS and AML patients in the time of COVID-19.
  Azra Raza, Amer Assal, Abdullah Mahmood Ali, Joseph G. Jurcic> ;Leukemia Research Reports. 2020 Apr 20
• 64 citations
  Disease-Causing Mutations in SF3B1 Alter Splicing by Disrupting Interaction with SUGP1.
  Jian Zhang, Abdullah Mahmood Ali, Yen K. Lieu, Zhaoqi Liu, Jianchao Gao, Raul Rabadan, Azra Raza, Siddhartha Mukherjee, James L. Manley> ;Molecular Cell. 2019 Oct 3
• 77 citations
  Gene-edited stem cells enable CD33-directed immune therapy for myeloid malignancies.
  Florence Borot, Hui Wang, Yan Ma, Toghrul Jafarov, Azra Raza, Abdullah Mahmood Ali, Siddhartha Mukherjee> ;Proceedings of the National Academy of Sciences of the United States of America. 2019 Jun 11
• 9 citations
  Improving Treatment for Myelodysplastic Syndromes Patients.
  Julia Montoro, Aslihan Yerlikaya, Abdullah Mahmood Ali, Azra Raza> ;Current Treatment Options in Oncology. 2018 Oct 25
• 18 citations
  Severely impaired terminal erythroid differentiation as an independent prognostic marker in myelodysplastic syndromes
  Abdullah Mahmood Ali, Yumin Huang, R.F. Pinheiro, Fumin Xue, Jingping Hu, Nicholas Iverson, Daniela Hoehn, Diego Coutinho, Jehanzeb Kayani, Brian Chernak, Joseph M. La...> ;Blood Advances. 2018 Jun 26
• 5 citations
  Survey and evaluation of mutations in the human KLF1 transcription unit.
  Merlin Nithya Gnanapragasam, John D. Crispino, Abdullah Mahmood Ali, Rona Singer Weinberg, Ronald Hoffman, Azra Raza, James J. Bieker> ;Scientific Reports. 2018 Apr 26
• 301 citations
  Long-term treatment with ruxolitinib for patients with myelofibrosis: 5-year update from the randomized, double-blind, placebo-controlled, phase 3 COMFORT-I trial.
  Srdan Verstovsek, Ruben A. Mesa, Jason Gotlib, Vikas Gupta, John F. DiPersio, John Catalano, Michael W. Deininger, Carole B. Miller, Richard T. Silver, Moshe Talpaz, E...> ;Journal of Hematology & Oncology. 2017 Feb 22
• 22 citations
  Recent advances in the treatment of lower-risk non-del(5q) myelodysplastic syndromes (MDS).
  Antonio Almeida, Pierre Fenaux, Alan F. List, Azra Raza, Uwe Platzbecker, Valeria Santini> ;Leukemia Research. 2017 Jan 1
• 265 citations
  Physiologic Expression of Sf3b1(K700E) Causes Impaired Erythropoiesis, Aberrant Splicing, and Sensitivity to Therapeutic Spliceosome Modulation.
  Esther A. Obeng, Ryan J. Chappell, Michael Seiler, Michelle C. Chen, Dean R. Campagna, Paul J. Schmidt, Rebekka K. Schneider, Allegra M. Lord, Lili Wang, Rutendo Gambe...> ;Cancer Cell. 2016 Sep 12
• 3 citations
  Two different “tales” of ATG7: Clinical relevance to myelodysplastic syndromes
  Abdullah Mahmood Ali, Azra Raza> ;Molecular & Cellular Oncology. 2016 Jul 26
• 1 citations
  Therapy-Associated Myeloid Dysplasia in a Long-Surviving Patient with Pancreatic Cancer
  Jillian Suzukida, Kristin Kaley, Azra Raza, Muhammad Wasif Saif> ;Cureus. 2016 Jul 13
• 47 citations
  Prospective international validation of the Quality of Life in Myelodysplasia Scale (QUALMS).
  Gregory A. Abel, Fabio Efficace, Rena Buckstein, Sara Tinsley, Joseph G. Jurcic, Yolanda Martins, David P. Steensma, Corey D. Watts, Azra Raza, Stephanie J. Lee, Alan ...> ;Haematologica. 2016 Jun 1
• 102 citations
  U2AF35(S34F) Promotes Transformation by Directing Aberrant ATG7 Pre-mRNA 3′ End Formation
  Sung Mi Park, Jianhong Ou, Lynn Chamberlain, Simone Tessa Mercedes, Huan Yang, Ching-Man A. Virbasius, Abdullah Mahmood Ali, Lihua Julie Zhu, Siddhartha Mukherjee, Azr...> ;Molecular Cell. 2016 May 19
• 103 citations
  Activity of the oral mitogen-activated protein kinase kinase inhibitor trametinib in RAS-mutant relapsed or refractory myeloid malignancies
  Gautam Borthakur, Leslie Popplewell, Michael Boyiadzis, James M. Foran, Uwe Platzbecker, Norbert Vey, Roland B. Walter, Rebecca L. Olin, Azra Raza, Aristoteles Giagoun...> ;Cancer. 2016 Jun 15
• 163 citations
  Disease-associated mutation in SRSF2 misregulates splicing by altering RNA-binding affinities.
  Jian Zhang, Yen K. Lieu, Abdullah Mahmood Ali, Alex Penson, Kathryn S. Reggio, Raul Rabadan, Azra Raza, Siddhartha Mukherjee, James L. Manley> ;Proceedings of the National Academy of Sciences of the United States of America. 2015 Aug 25
• 40 citations
  Clinical activity and safety of the dual pathway inhibitor rigosertib for higher risk myelodysplastic syndromes following DNA methyltransferase inhibitor therapy
  Lewis R. Silverman, Peter L. Greenberg, Azra Raza, Matthew J. Olnes, James F. Holland, Premkumar E Reddy, Manoj Maniar, Francois Wilhelm> ;Hematological Oncology. 2015 Jun 1
• Efficacy, safety, and survival with ruxolitinib in patients with myelofibrosis: results of a median 3-year follow-up of COMFORT-I.
  Verstovsek S, Mesa RA, Gotlib J, Levy RS, Gupta V, DiPersio JF, Catalano JV, Deininger MWN, Miller CB, Silver RT, Talpaz M, Winton EF, Harvey JH, Arcasoy MO, Hexner EO...> ;Haematologica. 2015-04-01
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