SiddharthaMukherjeeMD

PubMed

• 1 citations
  Development of a gene edited next-generation hematopoietic cell transplant to enable acute myeloid leukemia treatment by solving off-tumor toxicity.
  John R Lydeard, Michelle I Lin, Huanying Gary Ge, Amanda Halfond, Shu Wang, Mark B Jones, Julia Etchin, Gabriella Angelini, Juliana Xavier-Ferrucio, Jessica Lisle, Kie...> ;Molecular Therapy. Methods & Clinical Development. 2023 Dec 14
• 1 citations
  Loss of Grem1-lineage chondrogenic progenitor cells causes osteoarthritis.
  Jia Q Ng, Toghrul H Jafarov, Christopher B Little, Tongtong Wang, Abdullah M Ali, Yan Ma, Georgette A Radford, Laura Vrbanac, Mari Ichinose, Samuel Whittle, David J Hu...> ;Nature Communications. 2023 Oct 31
• 8 citations
  Randomized, double-blinded, placebo-controlled trial of allogeneic cord blood T-regulatory cells for treatment of COVID-19 ARDS.
  Douglas E Gladstone, Franco D'Alessio, Christopher Howard, Mi-Ae Lyu, Jason R Mock, Kevin W Gibbs, Darryl Abrams, Meixian Huang, Ke Zeng, James P Herlihy, Sergio T Cas...> ;Blood Advances. 2023 Jul 11
• The first SURS World Congress of Robotic Surgery at Mount Sinai Hospital in New York City: A tribute to the past and the future of robotic urologic surgery.
  Raghav Gupta, Deepak Chopra, Ashok K Hemal, Siddhartha Mukherjee, Craig G Rogers, Chandru P Sundaram, Ashutosh K Tewari> ;BJUI Compass. 2023 May 1
• Loss of-articular cartilage progenitor cells causes osteoarthritis.
  Jia Q Ng, Toghrul H Jafarov, Christopher B Little, Tongtong Wang, Abdullah Ali, Yan Ma, Georgette A Radford, Laura Vrbanac, Mari Ichinose, Samuel Whittle, David Hunter...> ;Biorxiv. 2023 Mar 30
• 5 citations
  Allogeneic cord blood regulatory T cells can resolve lung inflammation.
  Mi-Ae Lyu, Meixian Huang, Ke Zeng, Li Li, Joseph D Khoury, Mitsutaka Nishimoto, Hongbing Ma, Tara Sadeghi, Siddhartha Mukherjee, Arthur S Slutsky, Christopher R Flower...> ;Cytotherapy. 2023 Mar 1
• 1 citations
  A novel therapeutic bispecific format based on synthetic orthogonal heterodimers enables T cell activity against Acute myeloid leukemia.
  Alan Burke, Florence Borot, Xing Du, Michael Churchill, Jian Ding, Albert Mridul Grass, Philip DeSouza, Abdullah Mahmood Ali, Siddhartha Mukherjee> ;Oncogene. 2023 Jan 1
• 5 citations
  Post-vaccination outcomes in association with four COVID-19 vaccines in the Kingdom of Bahrain.
  Manaf AlQahtani, Xing Du, Sujoy Bhattacharyya, Abdulla Alawadi, Hamad Al Mahmeed, Jaleela Al Sayed, Jessica Justman, Wafaa M El-Sadr, Jack Hidary, Siddhartha Mukherjee> ;Scientific Reports. 2022 Jun 2
• 11 citations
  Subversion of Serotonin Receptor Signaling in Osteoblasts by Kynurenine Drives Acute Myeloid Leukemia.
  Marta Galán-Díez, Florence Borot, Abdullah Mahmood Ali, Junfei Zhao, Eva Gil-Iturbe, Xiaochuan Shan, Na Luo, Yongfeng Liu, Xi-Ping Huang, Brygida Bisikirska, Rossella ...> ;Cancer Discovery. 2022 Apr 1
• 62 citations
  The Origin and Contribution of Cancer-Associated Fibroblasts in Colorectal Carcinogenesis.
  Hiroki Kobayashi, Krystyna A Gieniec, Tamsin R M Lannagan, Tongtong Wang, Naoya Asai, Yasuyuki Mizutani, Tadashi Iida, Ryota Ando, Elaine M Thomas, Akihiro Sakai, Nobu...> ;Gastroenterology. 2022 Mar 1
• 23 citations
  SF3B1 mutant-induced missplicing of MAP3K7 causes anemia in myelodysplastic syndromes.
  Yen K Lieu, Zhaoqi Liu, Abdullah M Ali, Xin Wei, Alex Penson, Jian Zhang, Xiuli An, Raul Rabadan, Azra Raza, James L Manley, Siddhartha Mukherjee> ;Proceedings of the National Academy of Sciences of the United States of America. 2022 Jan 4
• 68 citations
  The Balance of Stromal BMP Signaling Mediated by GREM1 and ISLR Drives Colorectal Carcinogenesis.
  Hiroki Kobayashi, Krystyna A. Gieniec, Josephine A. Wright, Tongtong Wang, Naoya Asai, Yasuyuki Mizutani, Tadashi Lida, Ryota Ando, Nobumi Suzuki, Tamsin R M Lannagan,...> ;Gastroenterology. 2021 Mar 1
• Challenges and Solutions to Bringing Chimeric Antigen Receptor T-Cell Therapy to Myeloid Malignancies.
  Florence Borot, Siddhartha Mukherjee, Abdullah Mahmood Ali> ;Cancer Journal. 2021 Mar 1
• 12 citations
  Robust p53 Stabilization Is Dispensable for Its Activation and Tumor Suppressor Function.
  Ning Kon, Michael Churchill, Huan Li, Siddhartha Mukherjee, James J. Manfredi, Wei Gu> ;Cancer Research. 2021 Feb 15
• 4 citations
  Before Virus, After Virus: A Reckoning.
  Siddhartha Mukherjee> ;Cell. 2020 Oct 15
• 59 citations
  Aldehyde dehydrogenase 3a2 protects AML cells from oxidative death and the synthetic lethality of ferroptosis inducers.
  Rushdia Z. Yusuf, Borja Saez, Azeem Sharda, Nick van Gastel, Vionnie W.C. Yu, Ninib Baryawno, Elizabeth W. Scadden, Sanket S. Acharya, Shrikanta Chattophadhyay, Cherri...> ;Blood. 2020 Sep 10
• 6 citations
  Targeted Disruption of Bone Marrow Stromal Cell-Derived Gremlin1 Limits Multiple Myeloma Disease Progression In Vivo
  Kimberley C. Clark, Duncan R. Hewett, Vasilios Panagopoulos, Natalya Plakhova, Khatora S. Opperman, Alanah L. Bradey, Krzysztof M. Mrozik, Kate Vandyke, Siddhartha Muk...> ;Cancers. 2020 Aug 3
• 86 citations
  Medium-throughput Drug Screening of Patient-derived Organoids from Colorectal Peritoneal Metastases to Direct Personalized Therapy
  Vignesh Narasimhan, Josephine A. Wright, Michael Churchill, Tongtong Wang, Rachele Rosati, Tamsin R M Lannagan, Laura Vrbanac, Anne B Richardson, Hiroki Kobayashi, Tim...> ;Clinical Cancer Research. 2020 May 6
• 17 citations
  Stem cell-directed therapies for osteoarthritis: The promise and the practice.
  Jia Ng, Christopher B. Little, Susan L. Woods, Samuel L Whittle, Francis Y. Lee, Stan Gronthos, Siddhartha Mukherjee, David J. Hunter, Daniel L. Worthley> ;Stem Cells. 2020 Apr 1
• 65 citations
  Disease-Causing Mutations in SF3B1 Alter Splicing by Disrupting Interaction with SUGP1.
  Jian Zhang, Abdullah Mahmood Ali, Yen K. Lieu, Zhaoqi Liu, Jianchao Gao, Raul Rabadan, Azra Raza, Siddhartha Mukherjee, James L. Manley> ;Molecular Cell. 2019 Oct 3
• 77 citations
  Gene-edited stem cells enable CD33-directed immune therapy for myeloid malignancies.
  Florence Borot, Hui Wang, Yan Ma, Toghrul Jafarov, Azra Raza, Abdullah Mahmood Ali, Siddhartha Mukherjee> ;Proceedings of the National Academy of Sciences of the United States of America. 2019 Jun 11
• 6 citations
  Publisher Correction: Suppression of insulin feedback enhances the efficacy of PI3K inhibitors
  Benjamin D. Hopkins, Chantal Pauli, Xing Du, Diana G. Wang, Xiang Li, David Wu, Solomon C. Amadiume, Marcus D. Goncalves, Cindy Hodakoski, Mark R. Lundquist, Rohan Bar...> ;Nature. 2018 Nov 1
• 384 citations
  Suppression of insulin feedback enhances the efficacy of PI3K inhibitors
  Benjamin D. Hopkins, Chantal Pauli, Xing Du, Diana G. Wang, Xiang Li, David Wu, Solomon C. Amadiume, Marcus D. Goncalves, Cindy Hodakoski, Mark R. Lundquist, Rohan Bar...> ;Nature. 2018 Jul 4
• 2 citations
  Cancer, Our Genes, And The Anxiety Of Risk-Based Medicine.
  Siddhartha Mukherjee> ;Health Affairs. 2018 May 7
• 79 citations
  Genetic editing of colonic organoids provides a molecularly distinct and orthotopic preclinical model of serrated carcinogenesis
  Tasmin Rm Lannagan, Young K. Lee, Tongtong Wang, Jatin Roper, Mark Bettington, Lochlan Fennell, Laura Vrbanac, Lisa Jonavicius, Roshini Somashekar, Krystyna A. Gieniec...> ;Gut. 2017 Apr 1
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Journal Articles

• Publisher Correction: Suppression of Insulin Feedback Enhances the Efficacy of PI3K Inhibitors  
  Siddhartha Mukherjee, Marcus D Goncalves, Mark A Rubin, Nature
• Suppression of Insulin Feedback Enhances the Efficacy of PI3K Inhibitors  
  Marcus D Goncalves, Siddhartha Mukherjee, Mark A Rubin, Nature

Abstracts/Posters

• Casein Kinase 1 Delta Is a Novel Regulator of mRNA Translation and Druggable Target in Aggressive Lymphomas
  Siddhartha Mukherjee, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019

Lectures

• A Failure to Heal 
  American Association for Cancer Research, Washington, Dist Of Col - 6/12/2012