AlejandroSweet-CorderoMD

PubMed

• 7 citations
  Statistical algorithms improve accuracy of gene fusion detection.
  Gillian L. Hsieh, Rob Bierman, Linda Szabo, Alexander Lee, Donald E. Freeman, E. Alejandro Sweet-Cordero, Julia Salzman> ;Nucleic Acids Research. 2017 Jul 27
• Oncogenic KRAS Regulates Amino Acid Homeostasis and Asparagine Biosynthesis via ATF4 and Alters Sensitivity to L-Asparaginase.
  Gwinn DM, Lee AG, Briones-Martin-Del-Campo M, Conn CS, Simpson DR, Scott AI, Le A, Cowan TM, Ruggero D, Sweet-Cordero EA> ;Cancer cell.
• 30 citations
  Inhibition of activin signaling in lung adenocarcinoma increases the therapeutic index of platinum chemotherapy
  Kieren D. Marini, David R. Croucher, Rachael A. McCloy, Vijesh Vaghjiani, Alvaro Gonzalez-Rajal, Jordan F. Hastings, Venessa T. Chin, Anette Szczepny, Kaja Kostyrko, C...> ;Science Translational Medicine. 2018 Jul 25
• The genomic landscape of pediatric cancers: Implications for diagnosis and treatment.
  Sweet-Cordero EA, Biegel JA> ;Science (New York, N.Y.).
• 25 citations
  The Mir181ab1 cluster promotes KRAS-driven oncogenesis and progression in lung and pancreas
  Karmele Valencia, O. Erice, Kaja Kostyrko, Simone Hausmann, Elizabeth Guruceaga, Anuradha Tathireddy, Natasha M. Flores, Leanne C. Sayles, Alex G. Lee, Rita Fragoso, T...> ;The Journal of Clinical Investigation. 2020 Apr 1
• Genomic Complexity of Osteosarcoma and Its Implication for Preclinical and Clinical Targeted Therapies.
  Schott C, Shah AT, Sweet-Cordero EA> ;Advances in experimental medicine and biology.
• NUP98-NSD1 Driven MDS/MPN in Childhood Masquerading as JMML.
  Behnert A, Lee AG, Young EP, Breese MR, Leung SG, Behroozfard I, Maruffi M, Sweet-Cordero EA, Dvorak CC, Chu J, Stieglitz E> ;Journal of pediatric hematology/oncology. 2020-08-18
• 24 citations
  Combined Proteomic and Genetic Interaction Mapping Reveals New RAS Effector Pathways and Susceptibilities.
  Marcus R. Kelly, Kaja Kostyrko, Kyuho Han, Nancie Mooney, Edwin E. Jeng, Kaitlyn Spees, Phuong T. Dinh, Keene L. Abbott, E. Alejandro Sweet-Cordero, Michael C. Bassik,...> ;Cancer Discovery. 2020 Jul 29
• 13 citations
  Engineering a potent receptor superagonist or antagonist from a novel IL-6 family cytokine ligand
  Kim Jun Woo, Cesar P Marquez, R Andres Parra Sperberg, Jiaxiang Wu, Won G Bae, E. Alejandro Sweet-Cordero, Jennifer R. Cochran> ;Proceedings of the National Academy of Sciences of the United States of America. 2020 Jun 23
• 1 citations
  Hydra: A mixture modeling framework for subtyping pediatric cancer cohorts using multimodal gene expression signatures.
  Jacob Pfeil, Lauren Sanders, Ioannis N. Anastopoulos, A. Geoffrey Lyle, Alana S. Weinstein, Yuanqing Xue, Andrew Blair, Holly C. Beale, Alex G. Lee, Stanley G. Leung, ...> ;Plos Computational Biology. 2020 Apr 10
• 155 citations
  CRISPR screens in cancer spheroids identify 3D growth-specific vulnerabilities.
  Kyuho Han, Sarah E. Pierce, Amy Li, Kaitlyn Spees, Grace R. Anderson, Jose A. Seoane, Yuan-Hung Lo, Michael M. Dubreuil, Micah Olivas, Roarke A. Kamber, Michael Wainbe...> ;Nature. 2020 Mar 11
• 41 citations
  Antitumor activity of an engineered decoy receptor targeting CLCF1-CNTFR signaling in lung adenocarcinoma.
  Kim Jun Woo, Cesar P Marquez, Kaja Kostyrko, Amanda Koehne, Kieren D. Marini, David R. Simpson, Alex G. Lee, Stanley G. Leung, Leanne C. Sayles, Joseph B. Shrager, Ire...> ;Nature Medicine. 2019 Nov 1
• 3 citations
  Comparative RNA-seq analysis aids in diagnosis of a rare pediatric tumor.
  , , , , , , , , , , , , , , , , , , , , , , > ;Cold Spring Harbor Molecular Case Studies. 2019 Oct 23
• Ewing sarcoma in a child with neurofibromatosis type 1.
  Fernandez KS, Turski ML, Shah AT, Bastian BC, Horvai A, Hardee S, Sweet-Cordero EA> ;Cold Spring Harbor molecular case studies. 2019-10-23
• 33 citations
  Comparative Tumor RNA Sequencing Analysis for Difficult-to-Treat Pediatric and Young Adult Patients With Cancer
  , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , > ;JAMA Network Open. 2019 Oct 2
• Fusion driven JMML: a novel CCDC88C-FLT3 fusion responsive to sorafenib identified by RNA sequencing.
  Chao AK, Meyer JA, Lee AG, Hecht A, Tarver T, Van Ziffle J, Koegel AK, Golden C, Braun BS, Sweet-Cordero EA, Smith CC, Dvorak CC, Loh ML, Stieglitz E> ;Leukemia. 2019-09-12
• Provocative questions in osteosarcoma basic and translational biology: A report from the Children's Oncology Group.
  Roberts RD, Lizardo MM, Reed DR, Hingorani P, Glover J, Allen-Rhoades W, Fan T, Khanna C, Sweet-Cordero EA, Cash T, Bishop MW, Hegde M, Sertil AR, Koelsche C, Mirabell...> ;Cancer. 2019-07-29
• 16 citations
  Germline Predisposition and Copy Number Alteration in Pre-stage Lung Adenocarcinomas Presenting as Ground-Glass Nodules
  , , , , , , , , , , , , , , , , , , , , , , , , , > ;Frontiers in Oncology. 2019 Apr 18
• Genome-Informed Targeted Therapy for Osteosarcoma.
  Sayles LC, Breese MR, Koehne AL, Leung SG, Lee AG, Liu HY, Spillinger A, Shah AT, Tanasa B, Straessler K, Hazard FK, Spunt SL, Marina N, Kim GE, Cho SJ, Avedian RS, Mo...> ;Cancer discovery. 2018-09-28
• 30 citations
  Improvement in treatment abandonment in pediatric patients with cancer in Guatemala.
  Elysia Alvarez, Midori Seppa, Silvia Rivas, Lucia Fuentes, Patricia Valverde, Federico Antillon-Klussmann, E. Alejandro Sweet-Cordero, Kevin Messacar, John Kurap, Mari...> ;Pediatric Blood & Cancer. 2017 Oct 1
• 2 citations
  The present and the future of the RAS pathway: From function and genomics to inhibition
  Ignacio Gil-Bazo, Alejandro Sweet-Cordero, Silvestre Vicent> ;Cancer Biology & Therapy. 2016 May 21
• 34 citations
  The second European interdisciplinary Ewing sarcoma research summit--A joint effort to deconstructing the multiple layers of a complex disease.
  Heinrich Kovar, James F. Amatruda, Erika Brunet, Stefan Burdach, Florencia Cidre-Aranaz, Enrique de Alava, Uta Dirksen, Wietske van der Ent, Patrick J. Grohar, Thomas ...> ;Oncotarget. 2016 Jan 18
• 12 citations
  Preclinical Models Provide Scientific Justification and Translational Relevance for Moving Novel Therapeutics into Clinical Trials for Pediatric Cancer.
  David M. Langenau, Alejandro Sweet-Cordero, Robert J. Wechsler-Reya, Michael A. Dyer> ;Cancer Research. 2015 Dec 15
• 43 citations
  MEK1/2 Inhibition Elicits Regression of Autochthonous Lung Tumors Induced by KRASG12D or BRAFV600E
  Christy L. Trejo, Joseph Juan, Silvestre Vicent, Alejandro Sweet-Cordero, Martin McMahon> ;Cancer Research. 2012 Jun 15
• 80 citations
  Twist1 suppresses senescence programs and thereby accelerates and maintains mutant Kras-induced lung tumorigenesis.
  Phuoc T. Tran, Emelyn H. Shroff, Timothy F. Burns, Saravanan Thiyagarajan, Sandhya Das, Tahera Zabuawala, Joy Chen, Yoon Jae Cho, Richard Luong, Pablo Tamayo, T. Salih...> ;Plos Genetics. 2012 May 24
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