AlfredTLookJr.MD

PubMed

• Hyperactive STAT5 hijacks T cell receptor signaling and drives immature T cell acute lymphoblastic leukemia.
  Tobias Suske, Helena Sorger, Gabriele Manhart, Frank Ruge, Nicole Prutsch, Mark W Zimmerman, Thomas Eder, Diaaeldin I Abdallah, Barbara Maurer, Christina Wagner, Susan...> ;The Journal of Clinical Investigation. 2024 Apr 15
• STAT3 couples activated tyrosine kinase signaling to the oncogenic core transcriptional regulatory circuitry of anaplastic large cell lymphoma.
  Nicole Prutsch, Shuning He, Alla Berezovskaya, Adam D Durbin, Kelsey A Maher, Jamie D Matthews, Lucy Hare, Suzanne D Turner, Lukas Kenner, Olaf Merkel, Brian J Abraham...> ;Cell Reports. Medicine. 2024 Mar 19
• ASCL1 characterizes adrenergic neuroblastoma via its pioneer function and cooperation with core regulatory circuit factors.
  Wang, L., Tan, T., Kim, H., Kappei, D., Tan, S., Sanda, T., Look, A.> ;Cell Reports. 2023 Dec 26
• 2 citations
  Genetic predisposition to neuroblastoma results from a regulatory polymorphism that promotes the adrenergic cell state.
  Nina Weichert-Leahey, Hui Shi, Ting Tao, Derek A Oldridge, Adam D Durbin, Brian J Abraham, Mark W Zimmerman, Shizhen Zhu, Andrew C Wood, Deepak Reyon, J Keith Joung, R...> ;The Journal of Clinical Investigation. 2023 May 15
• 2 citations
  Targeting MET and FGFR in Relapsed or Refractory Acute Myeloid Leukemia: Preclinical and Clinical Findings, and Signal Transduction Correlates.
  Evan C Chen, Helen Gandler, Isidora Tošić, Geoffrey G Fell, Ashlee Fiore, Olga Pozdnyakova, Daniel J DeAngelo, Ilene Galinsky, Marlise R Luskin, Martha Wadleigh, Eric ...> ;Clinical Cancer Research. 2023 Mar 1
• 1 citations
  Synthetic lethal targeting of TET2-mutant haematopoietic stem and progenitor cells by XPO1 inhibitors.
  Chang-Bin Jing, Nicole Prutsch, Shuning He, Mark W Zimmerman, Yosef Landesman, A Thomas Look> ;British Journal of Haematology. 2023 May 1
• Depletion ofresults in age-dependent changes in DNA methylation and gene expression in a zebrafish model of myelodysplastic syndrome.
  Yaseswini Neelamraju, Evisa Gjini, Sagar Chhangawala, Hao Fan, Shuning He, Chang-Bin Jing, Ashley T Nguyen, Subhash Prajapati, Caroline Sheridan, Yariv Houvras, Ari Me...> ;Frontiers in Hematology. 2023 Jan 1
• p53 Pathway Inactivation Drives SMARCB1-deficient p53-wildtype Epithelioid Sarcoma Onset Indicating Therapeutic Vulnerability Through MDM2 Inhibition.
  Felix Oppel, Senyao Shao, Sarah Gendreizig, Mark W Zimmerman, Matthias Schürmann, Viyof Ful Flavian, Peter Goon, Susan N Chi, Jon C Aster, Holger Sudhoff, A Thomas Look> ;Molecular Cancer Therapeutics. 2022 Nov 3
• 43 citations
  EP300 selectively controls the enhancer landscape of MYCN-amplified neuroblastoma.
  Adam D. Durbin, Tingjian Wang, Virangika K. Wimalasena, Mark W. Zimmerman, Deyao Li, Neekesh V. Dharia, Luca Mariani, Noha A.M Shendy, Stephanie Nance, Anand G. Patel,...> ;Cancer Discovery. 2021 Nov 12
• 18 citations
  Retinoic acid rewires the adrenergic core regulatory circuitry of childhood neuroblastoma
  Mark W. Zimmerman, Adam D. Durbin, Shuning He, Felix Oppel, Hui Shi, Ting Tao, Zhaodong Li, Alla Berezovskaya, Yu Liu, Jinghui Zhang, Richard A. Young, Brian J. Abraha...> ;Science Advances. 2021 Oct 22
• 10 citations
  MEIS2 Is an Adrenergic Core Regulatory Transcription Factor Involved in Early Initiation of TH-MYCN-Driven Neuroblastoma Formation
  Jolien De Wyn, Mark W. Zimmerman, Nina Weichert-Leahey, Carolina de Carvalho Nunes, Belamy B. Cheung, Brian J. Abraham, Anneleen Beckers, Pieter-Jan Volders, Bieke Dec...> ;Cancers. 2021 Sep 24
• 18 citations
  Super-enhancer-based identification of a BATF3/IL-2R-module reveals vulnerabilities in anaplastic large cell lymphoma
  Huan Chang Liang, Mariantonia Costanza, Nicole Prutsch, Mark W. Zimmerman, Elisabeth Gurnhofer, Ivonne A. Montes-Mojarro, Brian J. Abraham, Nina Prokoph, Stefan Stoibe...> ;Nature Communications. 2021 Sep 22
• 9 citations
  Association of allele-specific methylation of the ASNS gene with asparaginase sensitivity and prognosis in T-ALL.
  Koshi Akahane, Shunsuke Kimura, Kunio Miyake, Atsushi Watanabe, Keiko Kagami, Kentaro Yoshimura, Tamao Shinohara, Daisuke Harama, Shin Kasai, Kumiko Goi, Tomoko Kawai,...> ;Blood Advances. 2021 Sep 17
• 3 citations
  Synergistic melanoma cell death mediated by inhibition of both MCL1 and BCL2 in high-risk tumors driven by NF1/PTEN loss.
  Shuning He, Mark W. Zimmerman, Hillary M. Layden, Alla Berezovskaya, Julia Etchin, Megan W. Martel, Grace Thurston, Chang-Bin Jing, Ellen van Rooijen, Charles K. Kaufm...> ;Oncogene. 2021 Jul 30
• 24 citations
  Metabolic Enzyme DLST Promotes Tumor Aggression and Reveals a Vulnerability to OXPHOS Inhibition in High-Risk Neuroblastoma.
  Nicole M. Anderson, Xiaodan Qin, Jennifer M. Finan, Andrew Lam, Jacob Athoe, Rindert Missiaen, Nicolas Skuli, Annie Kennedy, Amandeep S. Saini, Ting Tao, Shizhen Zhu, ...> ;Cancer Research. 2021 Jul 7
• 9 citations
  Integrative network analysis reveals USP7 haploinsufficiency inhibits E-protein activity in pediatric T-lineage acute lymphoblastic leukemia (T-ALL)
  Timothy I. Shaw, Li Dong, Liqing Tian, Chenxi Qian, Yu Liu, Bensheng Ju, Anthony A. High, Kanisha Kavdia, Vishwajeeth Pagala, Bridget Shaner, Deqing Pei, John Easton, ...> ;Scientific Reports. 2021 Mar 4
• 12 citations
  GAS7 Deficiency Promotes Metastasis in MYCN-driven Neuroblastoma
  Zhi-Wei Dong, Kok Siong Yeo, Gonzalo Lopez, Cheng Zhang, Erin N. Dankert Eggum, Jo Lynne Rokita, Choong Yong Ung, Taylor M. Levee, Zuag Paj Her, Cassie J. Howe, Xiaona...> ;Cancer Research. 2021 Jun 1
• 1 citations
  Targeting ganglioneuromas with mTOR inhibitors.
  Ting Tao, Hui Shi, Adam D. Durbin, A. Thomas Look> ;Molecular & Cellular Oncology. 2021 Jan 10
• 8 citations
  Ganglioneuromas are driven by activated AKT and can be therapeutically targeted with mTOR inhibitors.
  Ting Tao, Hui Shi, Meng Wang, Antonio R. Perez-Atayde, Wendy B. London, Alejandro Gutierrez, Bernardo Lemos, Adam D. Durbin, A. Thomas Look> ;The Journal of Experimental Medicine. 2020 Oct 5
• Correction: Dependency on the TYK2/STAT1/MCL1 axis in anaplastic large cell lymphoma.
  Nicole Prutsch, Elisabeth Gurnhofer, Tobias Suske, Huan Chang Liang, Michaela Schlederer, Simone Roos, Lawren C. Wu, Ingrid Simonitsch-Klupp, Andrea Alvarez-Hernandez,...> ;Leukemia. 2020 Nov 1
• 30 citations
  LIN28B regulates transcription and potentiates MYCN-induced neuroblastoma through binding to ZNF143 at target gene promotors.
  Ting Tao, Hui Shi, Luca Mariani, Brian J. Abraham, Adam D. Durbin, Mark W. Zimmerman, John T. Powers, Pavlos Missios, Kenneth N. Ross, Antonio R. Perez-Atayde, Martha ...> ;Proceedings of the National Academy of Sciences of the United States of America. 2020 Jul 14
• 3 citations
  inactivation in- and-deficient zebrafish accelerates the onset of malignant peripheral nerve sheath tumors and expands the spectrum of tumor types.
  Felix Oppel, Dong H Ki, Mark W Zimmerman, Kenneth N Ross, Ting Tao, Hui Shi, Shuning He, Jon C Aster, A Thomas Look> ;Disease Models & Mechanisms. 2020 Aug 27
• 37 citations
  Discovery of regulatory noncoding variants in individual cancer genomes by using cis-X.
  Yu Liu, Chunliang Li, Shuhong Shen, Xiao-Long Chen, Karol Szlachta, Michael N. Edmonson, Ying Shao, Xiaotu Ma, Judith Hyle, Shaela Wright, Bensheng Ju, Michael Rusch, ...> ;Nature Genetics. 2020 Jul 6
• 40 citations
  ARID1A loss in neuroblastoma promotes the adrenergic-to-mesenchymal transition by regulating enhancer-mediated gene expression
  Hui Shi, Ting Tao, Brian J. Abraham, Adam D. Durbin, Mark W. Zimmerman, Cigall Kadoch, A. Thomas Look> ;Science Advances. 2020 Jul 1
• 11 citations
  Synthetic lethal targeting of TET2-mutant hematopoietic stem and progenitor cells (HSPCs) with TOP1-targeted drugs and PARP1 inhibitors.
  Chang-Bin Jing, Cong Fu, Nicole Prutsch, Meng Wang, Shuning He, A. Thomas Look> ;Leukemia. 2020 Jun 22
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Journal Articles

• Selective Gene Dependencies in MYCN-Amplified Neuroblastoma Include the Core Transcriptional Regulatory Circuitry  
  William C Hahn, Todd R Golub, A Thomas Look, Adam D Durbin, Neekesh V Dharia, Kimberly Stegmaier, Nature
• The MCL1-Specific Inhibitor S63845 Acts Synergistically with venetoclax/ABT-199 to Induce Apoptosis in T-cell Acute Lymphoblastic Leukemia Cells  
  Alfred Look Jr., MD, Nature
• SCF(FBW7) Regulates Cellular Apoptosis by Targeting MCL1 for Ubiquitylation and Destruction  
  Inuzuka H, Shaik S, Onoyama I, Gao D, Tseng A, Maser RS, Zhai B, Wan L, Gutierrez A, Lau AW, Xiao Y, Christie AL, Aster J, Settleman J, Gygi SP, Kung AL, Look T, Nakay..., Nature, 1/1/2011
• NOTCH2 Links Protein Kinase C Delta to the Expression of CD23 in Chronic Lymphocytic Leukaemia (CLL) Cells  
  Hubmann R, Duchler M, Schnabl S, Hilgarth M, Demirtas D, Mitteregger D, Holbl A, Vanura K, Le T, Look T, Schwarzmeier JD, Valent P, Jager U, Shehata M, Br. J. Haematol, 1/1/2010
• Zebrafish Modelling of Leukaemias  
  Payne E, Look T, Br. J. Haematol, 1/1/2009
• Down-regulation of the Notch Pathway Mediated by a Gamma-secretase Inhibitor Induces Anti-tumour Effects in Mouse Models of T-cell Leukaemia  
  Tammam J, Ware C, Efferson C, O'Neil J, Rao S, Qu X, Gorenstein J, Angagaw M, Kim H, Kenific C, Kunii K, Leach KJ, Nikov G, Zhao J, Dai X, Hardwick J, Scott M, Winter ..., Br. J. Pharmacol, 1/1/2009
• Identification of Additional Cytogenetic and Molecular Genetic Abnormalities in Acute Myeloid Leukaemia with T(8;21)/AML1-ETO  
  Kuchenbauer F, Schnittger S, Look T, Gilliland G, Tenen D, Haferlach T, Hiddemann W, Buske C, Schoch C, Br. J. Haematol., 1/1/2006
• Making Waves in Cancer Research: New Models in the Zebrafish  
  Berghmans S, Jette C, Langenau D, Hsu K, Stewart R, Look T, Kanki JP, BioTechniques, 1/1/2005
• Investigator Profile An Interview with A Thomas Look, MD Interview by Vicki Glaser  
  Look AT, Zebrafish, 1/1/2005
• Evidence for an Age Cutoff Greater than 365 Days for Neuroblastoma Risk Group Stratification in the Children's Oncology Group  
  London WB, Castleberry RP, Matthay KK, Look AT, Seeger RC, Shimada H, Thorner P, Brodeur G, Maris JM, Reynolds CP, Cohn SL, J. Clin. Oncol, 1/1/2005
• Fusion of NUP214 to ABL1 on Amplified Episomes in T-cell Acute Lymphoblastic Leukemia  
  Graux C, Cools J, Melotte C, Quentmeier H, Ferrando A, Levine R, Vermeesch JR, Stul M, Dutta B, Boeckx N, Bosly A, Heimann P, Uyttebroeck A, Mentens N, Somers R, MacLe..., Nat. Genet., 1/1/2004
• Zebrafish Myelopoiesis and Blood Cell Development  
  Hsu K, Kanki JP, Look AT, Curr. Opin. Hematol, 1/1/2001
• Biological Aspects of Neuroblastomas Identified by Mass Screening in Quebec  
  Brodeur GM, Look AT, Shimada H, Hamilton VM, Maris JM, Hann HW, Leclerc JM, Bernstein M, Brisson LC, Brossard J, Lemieux B, Tuchman M, Woods WG, Med. Pediatr. Oncol., 1/1/2001
• Downregulation of Bim, a Proapoptotic Relative of Bcl-2, Is a Pivotal Step in Cytokine-initiated Survival Signaling in Murine Hematopoietic Progenitors  
  Shinjyo T, Kuribara R, Inukai T, Hosoi H, Kinoshita T, Miyajima A, Houghton PJ, Look AT, Ozawa K, Inaba T, Mol. Cell. Biol., 1/1/2001
• Natural History and Biology of Stage a Neuroblastoma: A Pediatric Oncology Group Study  
  Alvarado CS, London WB, Look AT, Brodeur GM, Altmiller DH, Thorner PS, Joshi VV, Rowe ST, Nash MB, Smith EI, Castleberry RP, Cohn SL, J. Pediatr. Hematol. Oncol., 1/1/2000
• Caspase 8 Is Deleted or Silenced Preferentially in Childhood Neuroblastomas with Amplification of MYCN  
  Teitz T, Wei T, Valentine MB, Vanin EF, Grenet J, Valentine VA, Behm FG, Look AT, Lahti JM, Kidd VJ, Nat. Med, 1/1/2000
• Parental Smoking and Alcohol Consumption and Risk of Neuroblastoma Cancer Epidemiol  
  Yang Q, Olshan AF, Bondy ML, Shah NR, Pollock BH, Seeger RC, Look AT, Cohn SL, Biomarkers Prev., 1/1/2000
• Reduced or Absent Expression and Codon 201Gly/Arg Polymorphism of DCC Gene in Rhabdomyosarcoma and Ewing's Sarcoma/PNET Family  
  Choi SH, Kong XT, Taki T, Tsuchida Y, Kawaguchi H, Kato H, Hanada R, Look AT, Hayashi Y, Int. J. Mol. Med., 1/1/2000
• Three Molecular Determinants of Malignant Conversion and Their Potential as Therapeutic Targets  
  Dome JS, Look AT, Curr Opin Oncol, 1/1/1999
• Identification of Newly Diagnosed Children with Acute Lymphocytic Leukemia at High Risk for Relapse  
  Shuster JJ, Camitta BM, Pullen J, Borowitz MJ, Carroll AJ, Look AT, Mahoney DH, Mahmoud H, Lauer SJ, Land VJ, Cancer Research Therapy and Control, 1/1/1999
• p27KIP1 Deletions in Childhood Acute Lymphoblastic Leukemia  
  Komuro H, Valentine MB, Rubnitz JE, Saito M, Raimondi SC, Carroll AJ, Yi T, Sherr CJ, Look AT, Neoplasia, 1/1/1999
• Arsenic and Apoptosis in the Treatment of Acute Promyelocytic Leukemia  
  Look AT, J. Natl. Cancer Inst, 1/1/1998
• Molecular Genetics of Childhood Leukemias  
  Rubnitz JE, Look AT, J. Pediatr. Hematol. Oncol, 1/1/1998
• Molecular Basis of Leukemogenesis  
  Rubnitz JE, Look AT, Curr. Opin. Hematol., 1/1/1998
• Prognostic Significance of Age, MYCN Oncogene Amplification, Tumor Cell Ploidy, and Histology in 110 Infants with Stage D(S) Neuroblastoma: The Pediatric Oncology Grou...  
  Katzenstein HM, Bowman LC, Brodeur GM, Thorner PS, Joshi VV, Smith EI, Look AT, Rowe ST, Nash MB, Holbrook T, Alvarado C, Rao PV, Castleberry RP, Cohn SL, J. Clin. Oncol., 1/1/1998
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Books/Book Chapters

• Oncology of Infancy and Childhood 
  Page 331.0 - 402.0Clark JJ, Berman JN, Look ATEditors: Orkin SH, Fisher DE, Look AT, Lux SE, Ginsburg D, Nathan DG.W.B. Saunders, Philadelphia, PA2009
• Molecular Biology of B Cells 
  Chapter: Chromosomal Translocations in B Cell Leukemias and Lymphomas 
  Page 1891. - 1900.Ferrando A. and Look ATEditors: Honjo T, Alt FW, Neuberger M.Elsevier Academic Press, London, UK2004
• Hematology of Infancy and Childhood 
  Chapter: Myeloid Leukemia, Myelodysplasia, and Myeloproliferative Disease in Children 
  Page 1167. - 1209.Bennett CM, Hsu K and Look ATEditors: Nathan DG, Orkin SH, Ginsburg D, Look AT.W.B. Saunders, Philadelphia, PAEdition 6th,2003
• Hematopoiesis: A Developmental Approach 
  Chapter: Aberrant Control of Cell Fate in the Leukemias and Lymphomas 
  Page 672.0 - 688.0Look ATOxford University Press, New York, NY2000
• The Genetic Basis of Human Cancer 
  Chapter: Genes Altered by Chromosomal Translocations in Leukemias and Lymphoma 
  Page 109.0 - 141.0Look ATEditors: Vogelstein B and Kinzler KW.New York, NY1998
• Principles and Practice of Pediatric Oncology 
  Chapter: Molecular Basis of Childhood Cancer 
  Page 37.0 - 74.0Look AT and Kirsch IREditors: Pizzo PA and Poplack DG.J. B. Lippincott Co., Philadelphia, PAEdition 3rd,1997
• Leucocyte Typing V 
  Chapter: Report of the CD13 (Aminopeptidase N) Cluster Workshop 
  Page 988.0 - 989.0Ashmun RA, Holmes KV, Shapiro LH, Favaloro EJ, Razak K, deCrom RPG, Howard CJ, Look ATEditors: Schlossman SF, et al..Oxford University Press, Oxford1995
• Molecular Biology in Cancer Medicine 
  Chapter: Cytogenetic and Molecular Defects in the Acute Lymphoid Leukemias 
  Page 174.0 - 195.0Downing JR and Look ATEditors: Kurzrock R, Talpaz M.Martin Dunitz, London1995
• Leukemia: Advances in Research and Treatment 
  Chapter: MLL Fusion Genes in the 11q23 Acute Leukemias 
  Page 72.0 - 92.0Downing JR and Look ATEditors: Freireich EJ.1995
• Hematology: Basic Principles and Practice 
  Chapter: Pathobiology of the Acute Lymphoid Leukemia Cell 
  Page 763.0 - 776.0Look ATEditors: Benz EJ, Cohen HJ, Furie B, Hoffman R, Shattil SJ.Churchill Livingstone, New Department of Experimental Oncology1991
• Biology of Human Leukemia 
  Chapter: Genetic Abnormalities in Human Leukemia 
  Look ATEditors: Mauer AM.Johns Hopkins University Press1989
• Constellations of Genetic Abnormalities Predict Clinical Outcome in Childhood Malignancies 
  Look AT1989
• Mechanisms of Action and Therapeutic Applications of Biologicals in Cancer and Immune Deficiency Disorders 
  Chapter: Expression of CSF-1 Receptors on Human Leukemic Blasts 
  Page 39.0 - 55.0Ashmun RA, Look AT, Roussel MF, Ohtsuka M, Sherr CJAlan R. Liss Inc.1989
• Leukocyte Typing IV 
  Chapter: Report of the CD13 (Aminopeptidase N) Cluster Workshop 
  Page 784.0 - 787.0Look AT, Ashmun RA, Shapiro LH, O'Connell PJ, Gerkis V, d'Apice AJ, Sagawa K, Peiper SCEditors: Knapp W.Oxford University Press, Oxford1989
• Leukocyte Typing IV 
  Chapter: Report of the CD33 Cluster Group Workshop: Biochemical and Genetic Characterization of gp67 
  Page 814.0 - 816.0Peiper SC, LeBoeuf RD, Hughes CB, Prasthofer EF, Borowitz MJ, Dewtter-Dambuyant, Katz DR, Walker WS, Ashmun RA, Look ATEditors: Knapp W.Oxford University Press, Oxford1989
• Leukocyte Typing IV 
  Chapter: Monoclonal Antibodies to the Human CSF-1 Receptor (C-fms Proto-oncogene Product) Define a New Myeloid Cluster Group 
  Page 941.0 - 943.0Ashmun RA, Look AT, Roussel MF, Ohtsuka M, Sherr CJEditors: Knapp W.Oxford University Press, Oxford1989
• Leukocyte Typing IV 
  Chapter: Summary of the CD14 Cluster Workshop 
  Page 789.0 - 794.0Goyert SM, Tesio L, Ashman LK, Ball E, Bazil V, Garrido F, Hogg N, Horejsi V, Howell A, Jayaram Y, Look AT, Ruiz-Cabello F, Schmitt D, Schneider M, van der Schoot CEEditors: Knapp W.Oxford University Press, Oxford1989
• Leukocyte Typing IV 
  Chapter: Report on the CD34 Cluster Workshop 
  Page 881.0 - 825.0Civin CI, Trischmann TM, Fackler MJ, Bernstein ID, Buhring H-J, Campos L, Greaves MF, Kamoun M, Katz DR, Landsdorp PM, Look AT, Seed B, Sutherland DR, Tindle RW, Uchan...Editors: Knapp W.Oxford University Press, Oxford1989
• Leukocyte Typing IV 
  Chapter: Summary of the Myeloid Workshop Transfectoma Studies 
  Page 880.0 - 886.0Stockinger H, Ashmun RA, Dougherty G, Franklin WA, Goyert SM, Hogarth M, Humphries K, Jose DG, Kasinrerk W, Landsdorp PM, Look AT, Pilkington G, Seed B, Tesio L, Willi...Editors: Knapp W.Oxford University Press, Oxford1989
• Molecular Diagnostics of Human Cancer 
  Chapter: Human CSF-1 Receptor (C-fms Proto-oncogene Product) On Normal and Leukemic Myeloid Cells 
  Ashmun RA, Look AT, Roussel MR, Ohtuska M, Sherr CJCold Spring Harbor Laboratory1989
• Leukocyte Typing III 
  Chapter: Binding of Independently Derived Monoclonal Antibodies to Unique Human Myeloid Differentiation Antigens 
  Page 626.0 - 629.0Look AT, Peiper SC, Ashmun RAEditors: McMichael AJ, et al..Oxford University Press, Oxford1987
• Leukocyte Typing III 
  Chapter: DNA Mediated Transfer of the Gene Encoding p67, a Myeloid Differentiation Antigen Recognized by the MY9, L1B2, and L4F3 Monoclonal Antibodies 
  Page 622.0 - 625.0Peiper SC, Lemons RS, Ashmun RA, Look ATOxford University Press, Oxford1987
• Cancer Biology and Therapeutics 
  Chapter: Relationships of Cell Biology to Therapy in Childhood Leukemia 
  Page 161.0 - 172.0Look AT, Williams DL, Simone JVEditors: Cory JG, Szentivanyi A.Plenum Publishing, New York1986
• Leukocyte Typing 
  Chapter: Changes in Cell Surface Antigen Expression during Myelocytic and Monocytic Cell Differentiation 
  Page 442.0 - 446.0Mirro J, Melvin S, Metzger D, Look AT, Murphy SBEditors: Bernard A, Boumsell L.Springer Verlag1984
• New Approaches in Cancer Therapy 
  Chapter: VP 16 213 and 5 Azacytidine for Remission Induction of Refractory Acute Nonlymphocytic Leukemia 
  Dahl GV, Look AT, Rivera GEditors: Cortes Funes H, Rozencweig M.Raven Press, New York1982
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Abstracts/Posters

• Therapy of Childhood Leukemia -understanding Success and Failure
  Simone JV, Rivera GK, Look AT, Crist WM, Proc of 20th Anniversary Symposium, Children's Cancer Association of Japan, 1/1/1989

Lectures

• Phase I Study of the Selinexor in Relapsed/Refractory Childhood Acute Leukemia 
  2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
• Emerging features of Super-Enhancers in T-Cell acute Leukemia 
  Boston University School of Medicine - 1/1/2015
• Inherited and Somatically Acquired Super-Enhancers in Development Cancers 
  Denver, Colorado - 1/1/2015
• Pediatric Cancer: Basic Science III 
  Philadelphia - 1/1/2015
• Zebrafish Models to Dissect Human Cancers 
  Bar Harbor, Maine - 1/1/2015
• Oncogene Regulation by Super-enhance Formulation 
  1/1/2015
• A Zebrafish Model of Myelodysplastic Syndrome Produced Through tet2 Genomic Editing 
  Pacific Grove, CA - 1/1/2015
• A Zebrafish Model of Myeloid Malignacy Produced Through tet2 and asxl1 Genomic Editing 
  Hawaii - 1/1/2015
• Central Role for Super-Enhancers in T-cell Leukemia 
  Berlin, Germany - 1/1/2015
• Central Role of Super-enhancers in T-Cell Acute Leukemia 
  Berlin, Germany - 1/1/2015
• Targeting Pathway Addiction to the TYK2 Kinase in T-cell Acute Lymphoblastic Leukemia 
  Moores UCSD Cancer Center, University of California, San Diego - 1/1/2014
• The Interface of GWAS and Zebrafish-LMO1 Controls the Rate of Neuroblastoma 
  San Diego - 1/1/2014
• Targeting of Nuclear Export in Primary AML Cells 
  New York - 1/1/2014
• Faithful Zebrafish Models of High Risk Neuroblastoma Promise New Advances in Personalized Medicine 
  Halifax, NS, Canada - 1/1/2014
• Zebrafish Models to Dissect Cancer 
  Bar Harbor, Maine - 1/1/2014
• Core Transcriptional Regulatory Circuit Controlled by the TAL1 Complex in Human T-cell Acute Lymphoblastic Leukemia 
  Univeristy of Pennslyvania Perelman School of Medicine ,Philadelphia, PA - 1/1/2013
• Aberrant Expression of Hepatocyte Growth Factor Induces Autocrine MET Activation in Acute Myeloid Leukemia 
  Van Andel Institute Grand Rapids, Michigan - 1/1/2013
• MYBL2 Is a Sub-haploinsufficient Tumor Suppressor Gene in Myeloid Malignancy 
  Maui , Hawaii - 1/1/2013
• Autocrine Activation of MET and Strategies to Overcome Adaptation for the Targeted Therapy of Acute Myeloid Leukemia 
  Washington, D.C. - 1/1/2013
• Role of the LMO1 Oncogene in Neuroblastoma Pathogenesis 
  Barcelona, Spain, 2013; Murcia, Spain, 2013 - 1/1/2013
• ALK Mutations and Mechanisms of Transformation in Neuroblastoma 
  Heidelberg, Germany - 1/1/2013
• MYBL2 is a Tumor Suppressor Gene in Myelodysplastic Syndromes 
  Stanford University School of Medicine, Stanford, California - 1/1/2012
• New Advances Molecular Pathogenesis and Pathway Dependence in T-cell ALL 
  Stowers Institute for Medical Research, Kansas City, Missouri - 1/1/2012
• Addiction to a Non-Canonical Interferon Receptor-TYK2-STAT1 Pathway in Human T-ALL 
  Memorial Sloan-Kettering Cancer Center, New York, New York - 1/1/2011
• Recent Advances in T-ALL: Addiction to a Non-Canonical Interferon Receptor-TYK2-STAT1 Pathway 
  University of Chicago Comprehensive Cancer Center, Chicago, Illinois - 1/1/2011
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