AnaCristanchoMDPhD

Pediatrics • Philadelphia, PA

Child Neurology

Resident

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Office
3500 Civic Center Blvd
Philadelphia, PA 19104
Phone+1 215-590-1000
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Education & Training

Children's Hospital of PhiladelphiaChief Residency, Child Neurology, 2017 - 2018
University of Pennsylvania Health SystemResidency, Neurology, 2015 - 2018
Children's Hospital of PhiladelphiaResidency, Child Neurology, 2015 - 2018
Children's Hospital of PhiladelphiaResidency, Pediatrics, 2013 - 2016
Perelman School of Medicine at the University of PennsylvaniaClass of 2013

Certifications & Licensure

PA State Medical License 2013 - 2024
American Board of Psychiatry and Neurology Neurology with Special Qualification in Child Neurology

Publications & Presentations

PubMed

Fetus with multiple congenital anomaly syndrome caused by novel variant in ATP1A2.
Natalie Burrill, Beverly Coleman, Jill Murrell, Julie S Moldenhauer, Nahla Khalek, Ana G Cristancho> ;Prenatal Diagnosis. 2024 Mar 28
Vaginal microbes alter epithelial transcriptomic and epigenomic modifications providing insight into the molecular mechanisms for susceptibility to adverse reproductiv...
Lauren Anton, Briana Ferguson, Andrea Joseph, Jacques Ravel, Elovitz, M., Cristancho, A.> ;Research Square. 2023 Nov 16
Neonatal Medullary Venous Thrombosis and Hemorrhage from Protein C Deficiency.
Margaret J Means, Matthew T Whitehead, Alexandra J Borst, Ana G Cristancho> ;Neuropediatrics. 2023 Aug 1
1 citations
Developmental Brain Injury and Social Determinants of Health: Opportunities to Combine Preclinical Models for Mechanistic Insights into Recovery.
Danielle Guez-Barber, Amelia J Eisch, Ana G Cristancho> ;Developmental Neuroscience. 2023 Jan 1
3 citations
Intrauterine Inflammation Leads to Select Sex- and Age-Specific Behavior and Molecular Differences in Mice.
Ana G Cristancho, Natalia Tulina, Amy G Brown, Lauren Anton, Guillermo Barila, Michal A Elovitz> ;International Journal of Molecular Sciences. 2022 Dec 20
A Simplified Paradigm of Late Gestation Transient Prenatal Hypoxia to Investigate Functional and Structural Outcomes from a Developmental Hypoxic Insult.
Elyse C Gadra, Ana G Cristancho> ;Bio-Protocol. 2022 Oct 5
4 citations
Six new cases of CRB2-related syndrome and a review of clinical findings in 28 reported patients.
Michelle Adutwum, Anna Hurst, Ghayda Mirzaa, Jessica D Kushner, Caleb Rogers, Nahla Khalek, Ana G Cristancho, Natalie Burrill, Michael E Seifert, Maria I Scarano, Rhon...> ;Clinical Genetics. 2023 Jan 1
5 citations
Deficits in Seizure Threshold and Other Behaviors in Adult Mice without Gross Neuroanatomic Injury after Late Gestation Transient Prenatal Hypoxia.
Ana G Cristancho, Elyse C Gadra, Ima M Samba, Chenying Zhao, Minhui Ouyang, Sergey Magnitsky, Hao Huang, Angela N Viaene, Stewart A Anderson, Eric D Marsh> ;Developmental Neuroscience. 2022 Jan 1
3 citations
Protocol for isolating young adult parvalbumin interneurons from the mouse brain for extraction of high-quality RNA.
Donald J. Joseph, Markus von Deimling, Yuiko Hasegawa, Ana G. Cristancho, Rashmi M. Risbud, Almedia J. McCoy, Eric D. Marsh> ;STAR Protocols. 2021 Aug 4
21 citations
An mtDNA mutant mouse demonstrates that mitochondrial deficiency can result in autism endophenotypes
Tal Yardeni, Ana G. Cristancho, Almedia J. McCoy, Patrick M. Schaefer, Meagan J. McManus, Eric D. Marsh, Douglas C. Wallace> ;Proceedings of the National Academy of Sciences of the United States of America. 2021 Feb 9
3 citations
Boricua Founder Variant in FRRS1L Causes Epileptic Encephalopathy With Hyperkinetic Movements.
Imane Abdelmoumen, Sandra Jimenez, Ignacio Valencia, Joseph J. Melvin, Agustin Legido, Mayela M. Diaz-Diaz, Christopher C. Griffith, Lauren J. Massingham, Melissa Yelt...> ;Journal of Child Neurology. 2021 Feb 1
5 citations
Postnatal Arx transcriptional activity regulates functional properties of PV interneurons.
Donald J. Joseph, Markus von Deimling, Yuiko Hasegawa, Ana G. Cristancho, Rebecca C. Ahrens-Nicklas, Stephanie L. Rogers, Rashmi M. Risbud, Almedia J. McCoy, Eric D. M...> ;Iscience. 2021 Jan 22
6 citations
Epigenetics modifiers: potential hub for understanding and treating neurodevelopmental disorders from hypoxic injury
Ana G. Cristancho, Eric D. Marsh> ;Journal of Neurodevelopmental Disorders. 2020 Dec 16
3 citations
Correction: IQSEC2-related encephalopathy in males and females: a comparative study including 37 novel patients
Cyril Mignot, Aoife McMahon, Claire Bar, Philippe M. Campeau, Claire Davidson, Julien Buratti, Caroline Nava, Marie Line Jacquemont, Marilyn Tallot, Mathieu Milh, Patr...> ;Genetics in Medicine. 2019 Aug 1
44 citations
IQSEC2-related encephalopathy in males and females: a comparative study including 37 novel patients
Cyril Mignot, Aoife Ac McMahon, Claire Bar, Philippe Pm Campeau, Claire Davidson, Julien Buratti, Caroline Nava, Marie-Line Jacquemont, Marilyn Tallot, Mathieu Milh, P...> ;Genetics in Medicine. 2019 Apr 1
2 citations
Ocular Dipping in a Patient With Hemiplegic Migraine.
Iga N Gray, Ana G. Cristancho, Daniel J. Licht, Grant T. Liu> ;Journal of Pediatric Ophthalmology and Strabismus. 2018 Jan 31
18 citations
A patient with lissencephaly, developmental delay, and infantile spasms, due to de novo heterozygous mutation of KIF2A.
Guoling Tian, Ana G. Cristancho, Holly Dubbs, Grant T. Liu, Nicholas J. Cowan, Ethan M. Goldberg> ;Molecular Genetics & Genomic Medicine. 2016 Sep 28
2 citations
Double SET Point: G9a Makes Its Mark in Adipogenesis
Ana G. Cristancho, Mitchell A. Lazar> ;The EMBO Journal. 2012 Nov 27
959 citations
Forming functional fat: a growing understanding of adipocyte differentiation
Ana G. Cristancho, Mitchell A. Lazar> ;Nature Reviews. Molecular Cell Biology. 2011 Sep 28
33 citations
Repressor transcription factor 7-like 1 promotes adipogenic competency in precursor cells
Ana G. Cristancho, Michael Schupp, Martina I. Lefterova, Shengya Cao, Daniel Cohen, Christopher S. Chen, David J. Steger, Mitchell A. Lazar> ;Proceedings of the National Academy of Sciences of the United States of America. 2011 Sep 27
58 citations
Re-expression of GATA2 Cooperates with Peroxisome Proliferator-activated Receptor-γ Depletion to Revert the Adipocyte Phenotype
Michael Schupp, Ana G. Cristancho, Martina I. Lefterova, Elyisha A. Hanniman, Erika R. Briggs, David J. Steger, Mohammed Qatanani, Joshua C. Curtin, Jonathan Schug, Sc...> ;The Journal of Biological Chemistry. 2009 Apr 3
70 citations
Retinol saturase promotes adipogenesis and is downregulated in obesity
Michael Schupp, Martina I. Lefterova, Jürgen Janke, Kirstin Leitner, Ana G. Cristancho, Shannon E. Mullican, Mohammed Qatanani, Nava R. Szwergold, David J. Steger, Jos...> ;Proceedings of the National Academy of Sciences of the United States of America. 2009 Jan 27
623 citations
PPARγ and C/EBP factors orchestrate adipocyte biology via adjacent binding on a genome-wide scale
Martina I. Lefterova, Yong Zhang, David J. Steger, Michael Schupp, Jonathan Schug, Ana G. Cristancho, Dan Feng, David Zhuo, Christian J. Stoeckert, X. Shirley Liu, Mit...> ;Genes & Development. 2008 Nov 1
28 citations
Stereospecificity of Retinol Saturase: Absolute Configuration, Synthesis, and Biological Evaluation of Dihydroretinoids
Alexander R. Moise, Marta Domínguez, Susana Alvarez, R. Alvarez, Michael Schupp, Ana G. Cristancho, Philip D. Kiser, Angel R. de Lera, Mitchell A. Lazar, Krzysztof Pal...> ;Journal of the American Chemical Society. 2008 Jan 30
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Journal Articles

IQSEC2-Related Encephalopathy in Males and Females: A Comparative Study Including 37 Novel Patients
Natasha Shur, Ethan M Goldberg, Katherine L Helbig, Ana G Cristancho, Nature