AnnaVachaparampilMathewMD

PubMed

• Tubular dysfunction impairs renal excretion of pseudouridine in diabetic kidney disease.
  Anna V Mathew, Pradeep Kayampilly, Jaeman Byun, Viji Nair, Farsad Afshinnia, Biaoxin Chai, Frank C Brosius 3rd, Matthias Kretzler, Subramaniam Pennathur> ;American Journal of Physiology. Renal Physiology. 2024 Jan 1
• 1 citations
  Low concentrations of medium-sized HDL particles predict incident CVD in chronic kidney disease patients.
  Baohai Shao, Farsad Afshinnia, Anna V Mathew, Graziella E Ronsein, Carissa Thornock, Angela D Irwin, Mayank Kansal, Panduranga S Rao, Mirela Dobre, Sadeer Al-Kindi, Ma...> ;Journal of Lipid Research. 2023 Jun 1
• 2 citations
  Kynurenine pathway metabolites predict subclinical atherosclerotic disease and new cardiovascular events in chronic kidney disease.
  Trista Benitez, Elizabeth VanDerWoude, Yun Han, Jaeman Byun, Vetalise Cheofor Konje, Brenda W Gillespie, Rajiv Saran, Anna V Mathew> ;Clinical Kidney Journal. 2022 Oct 1
• 8 citations
  Trans-ethnic genome-wide association study of blood metabolites in the Chronic Renal Insufficiency Cohort (CRIC) study.
  Eugene P Rhee, Aditya Surapaneni, Zihe Zheng, Linda Zhou, Diptavo Dutta, Dan E Arking, Jingning Zhang, ThuyVy Duong, Nilanjan Chatterjee, Shengyuan Luo, Pascal Schloss...> ;Kidney International. 2022 Apr 1
• 10 citations
  Mitochondrial complex II in intestinal epithelial cells regulates T cell-mediated immunopathology.
  Hideaki Fujiwara, Keisuke Seike, Michael D. Brooks, Anna V. Mathew, Ilya Kovalenko, Anupama Pal, Ho-Joon Lee, Daniel Peltier, Stephanie Kim, Chen Liu, Katherine Oravec...> ;Nature Immunology. 2021 Oct 22
• 12 citations
  Altered HDL Proteome Predicts Incident CVD in Chronic Kidney Disease Patients.
  Baohai Shao, Anna V. Mathew, Carissa Thornock, Subramaniam Pennathur> ;Journal of Lipid Research. 2021 Jan 1
• 15 citations
  Tryptophan levels associate with incident cardiovascular disease in chronic kidney disease.
  Vetalise C Konje, Thekkelnaycke M. Rajendiran, Keith Bellovich, Crystal A. Gadegbeku, Debbie S. Gipson, Farsad Afshinnia, Anna V. Mathew> ;Clinical Kidney Journal. 2021 Apr 2
• 2 citations
  Deletion of bone marrow myeloperoxidase attenuates chronic kidney disease accelerated atherosclerosis.
  Anna V Mathew, Lixia Zeng, Kevin B Atkins, Kiana N Sadri, Jaeman Byun, Hideaki Fujiwara, Pavan Reddy, Subramaniam Pennathur> ;The Journal of Biological Chemistry. 2020 Dec 3
• 54 citations
  Critical Role for AMPK in Metabolic Disease-Induced Chronic Kidney Disease
  Florian Juszczak, Nathalie Caron, Anna V. Mathew, Anne-Emilie Decleves> ;International Journal of Molecular Sciences. 2020 Oct 27
• 39 citations
  Impaired Amino Acid and TCA Metabolism and Cardiovascular Autonomic Neuropathy Progression in Type 1 Diabetes.
  Anna V. Mathew, Mamta Jaiswal, Lynn Ang, George Michailidis, Subramaniam Pennathur, Rodica Pop-Busui> ;Diabetes. 2019 Oct 1
• 7 citations
  AMP-activated protein kinase activation ameliorates eicosanoid dysregulation in high-fat-induced kidney disease in mice.
  Anne-Emilie Declèves, Anna V Mathew, Aaron M Armando, Xianlin Han, Edward A Dennis, Oswald Quehenberger, Kumar Sharma> ;Journal of Lipid Research. 2019 May 1
• 32 citations
  Host NLRP6 exacerbates graft-versus-host disease independent of gut microbial composition.
  Tomomi Toubai, Hideaki Fujiwara, Corinne Rossi, Mary Riwes, Hiroya Tamaki, Cynthia Zajac, Chen Liu, Anna V. Mathew, Jaeman Byun, Katherine Oravecz-Wilson, Ikuo Matsuda...> ;Nature Microbiology. 2019 Mar 11
• Response to Comment on Mathew Et Al. Therapeutic Lifestyle Changes Improve HDL Function by Inhibiting Myeloperoxidase-Mediated Oxidation in Patients With Metabolic Syn...
  Anna V. Mathew, Subramaniam Pennathur> ;Diabetes Care. 2019 Feb 1
• 95 citations
  Salt-Responsive Metabolite, β-Hydroxybutyrate, Attenuates Hypertension.
  Saroj Chakraborty, Sarah Galla, Xi Cheng, Jiyoun Yeo, Blair Mell, Vishal Singh, Beng San Yeoh, Piu Saha, Anna V. Mathew, Matam Vijay-Kumar, Bina Joe> ;Cell Reports. 2018 Oct 16
• 62 citations
  Disparate effects of antibiotics on hypertension
  Sarah Galla, Saroj Chakraborty, Xi Cheng, Jiyoun Yeo, Blair Mell, Helen Zhang, Anna V. Mathew, Matam Vijay-Kumar, Bina Joe> ;Physiological Genomics. 2018 Oct 1
• 23 citations
  Therapeutic Lifestyle Changes Improve HDL Function by Inhibiting Myeloperoxidase-Mediated Oxidation in Patients With Metabolic Syndrome
  Anna V. Mathew, Lei Li, Jaeman Byun, Yanhong Guo, George Michailidis, Mamta Jaiswal, Y. Eugene Chen, Rodica Pop-Busui, Subramaniam Pennathur> ;Diabetes Care. 2018 Sep 10
• 17 citations
  Effect of Ambient Fine Particulate Matter Air Pollution and Colder Outdoor Temperatures on High-Density Lipoprotein Function.
  Anna V. Mathew, Joyce Yu, Yanhong Guo, Jaeman Byun, Y. Eugene Chen, Lu Wang, M Liu, Robert L. Bard, Masako Morishita, Wei Huang, Jianping Li, Jack R. Harkema, Sanjay R...> ;The American Journal of Cardiology. 2018 Aug 15
• 18 citations
  Myeloperoxidase derived oxidants damage artery wall proteins in an animal model of chronic kidney disease accelerated atherosclerosis
  Lixia Zeng, Anna V. Mathew, Jaeman Byun, Kevin B. Atkins, Frank C. Brosius, Subramaniam Pennathur> ;The Journal of Biological Chemistry. 2018 May 11
• 23 citations
  Apolipoprotein A-1 mimetic peptide 4F promotes endothelial repairing and compromises reendothelialization impaired by oxidized HDL through SR-B1
  Dan He, Mingming Zhao, Congying Wu, Wenjing Zhang, Chenguang Niu, Baoqi Yu, Jingru Jin, Liang Ji, Belinda Willard, Anna V. Mathew, Y. Eugene Chen, Subramaniam Pennathu...> ;Redox Biology. 2018 May 1
• 17 citations
  Myeloperoxidase mediated HDL oxidation and HDL proteome changes do not contribute to dysfunctional HDL in Chinese subjects with coronary artery disease.
  Guisong Wang, Anna V. Mathew, Haiyi Yu, Lei Li, Liyun He, Wei Gao, Xiaodan Liu, Yanhong Guo, Jaeman Byun, Jifeng Zhang, Y. Eugene Chen, Subramaniam Pennathur> ;Plos One. 2018 Mar 5
• 27 citations
  Gut Microbial Product Predicts Cardiovascular Risk in Chronic Kidney Disease Patients.
  Adil Jadoon, Anna V. Mathew, Jaeman Byun, Crystal A. Gadegbeku, Debbie S. Gipson, Farsad Afshinnia, Subramaniam Pennathur> ;American Journal of Nephrology. 2018 Jan 1
• Preservation of Residual Kidney Function in Hemodialysis Patients: Reviving an Old Concept
  Steven Fishbane, Anna T Mathew> ;The ISN.
• 34 citations
  Deficiency of Cholesteryl Ester Transfer Protein Protects Against Atherosclerosis in Rabbits
  Jifeng Zhang, Manabu Niimi, Dongshan Yang, Jingyan Liang, Jie Xu, Tokuhide Kimura, Anna V. Mathew, Yanhong Guo, Yanbo Fan, Tianqing Zhu, Jun Song, Rose Ackermann, Yui ...> ;Arteriosclerosis, Thrombosis, and Vascular Biology. 2017 Jun 1
• 68 citations
  Circulating Modified Metabolites and a Risk of ESRD in Patients With Type 1 Diabetes and Chronic Kidney Disease
  Monika A. Niewczas, Anna V. Mathew, Stephanie Croall, Jaeman Byun, Melissa Major, Venkatta S. Sabisetti, Adam M. Smiles, Joseph V. Bonventre, Subramaniam Pennathur, An...> ;Diabetes Care. 2017 Mar 1
• 47 citations
  Treatment frequency and mortality among incident hemodialysis patients in the United States comparing incremental with standard and more frequent dialysis
  Anna T. Mathew, Yoshitsugu Obi, Connie M. Rhee, Joline L.T. Chen, Gaurang M. Shah, Wei Ling Lau, Csaba P. Kovesdy, Rajnish Mehrotra, Kamyar Kalantar-Zadeh> ;Kidney International. 2016 Nov 1
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Journal Articles

• Metabolic Signature of Chronic Kidney Disease: the search continues  
  Mathew AV, Pennathur S, American Journal of Kidney Disease, 1/1/2012
• Obesity related kidney disease  
  Anna V. Mathew, Shinichi Okada and Kumar Sharma, Current Diabetes Reviews, 1/1/2011
• Antifibrotic treatment and other new strategies for improving renal outcomes  
  Mathew A, Cunard R, Sharma K, Contrib Nephrol, 1/1/2011

Books/Book Chapters

• Encyclopedia of Medical Immunology 2014 
  Chapter: Macrophages, Oxidative Stress and Atherosclerosis. 
  Anna V. Mathew and Subramaniam PennathurEditors: Mackay I and Rose NR.EPub Springer2014

Abstracts/Posters

• Microbial metabolites modulate GI mucosal damage from graft versus host disease (GHVD).
  Nathan Mathewson, Anna V. Mathew, Katherine Oravecz-Wilson, Julia Wu, Tomomi Toubai, Emily Cummings, Subramaniam Pennathur and Pavan Reddy, The Journal of Immunology, 5/1/2014
• In vivo LC/MS-based Metabolic Flux Analysis to Delineate Nucleotide Metabolism in Diabetes. Poster Presentation
  Mathew AV, Byun J, Kayampily P, Afshinnia F, Pennathur S, American Society of Mass Spectrometry, Baltimore, MD, 1/1/2014
• Creation of a Reproducible Mass, Retention Time and Tandem Mass Spectral based Library and its Application in Clinical Research. Poster Presentation
  Zhang L, Mathew AV, Byun J, Pennathur S, American Society of Mass Spectrometry, Baltimore, MD, 1/1/2014
• Tubular Dysfunction Results in Altered Nucleoside Metabolism in Diabetic Nephropathy.
  Anna V. Mathew, Farsad Afshinnia, Jaeman Byun, Pradeep Kayampilly, Frank Brosius and Subramaniam Pennathur, ASN, Philadelphia, PA, 1/1/2014
• Microbial metabolites modulate GI mucosal damage from graft versus host disease (GVHD). Poster Presentation
  Mathewson N, Mathew AV, Oravecz-Wilson K, Wu J, Toubai T, Cummings E, Pennathur S, Reddy P, Immunology, Pittsburgh, PA, 1/1/2014
• Targeted LC/MS based metabolomic platform for quantification of nucleosides in biofluids: Potential biomarkers for Chronic Kidney Disease. Poster Presentation
  Anna V. Mathew, Jaeman Byun, and Subramaniam Pennathur, American Society of Nephrology, Atlanta, GA, 1/1/2013
• Global Metabolomic Profile in Type 2 Diabetes and Subsequent Progression to ESRD. Poster Presentation
  Niewczas M, Sirich T, Mathew AV, Skupien J, Mohney R, Warram J, Smiles A, Huang X, Walker W, Byun J, Karoly E, Kensicki E, Berry G, Bonventre J, Pennathur S, Meyer T, ..., American Society of Nephrology, Atlanta, GA, 1/1/2013
• Novel method for the quantification of Nucleosides in biological fluids with Liquid Chromatography based Mass Spectrometry. Poster Presentation
  Jaeman Byun, Anna V. Mathew and Subramaniam Pennathur, American Society of Mass Spectrometry, Minneapolis, MN, 1/1/2013
• Altered Arginine Methylation, oxidative stress and vascular dysfunction contribute to Accelerated Atherosclerosis in an Animal Model of Chronic Kidney Disease. Poster ...
  Lixia Zeng, Anna Mathew, Jaeman Byun, Kevin Atkins, Frank Brosius and Subramaniam Pennathur, American Society of Nephrology, San Diego, CA, 1/1/2012
• Role of AMPK and Adiponectin in Early Kidney disease. Poster Presentation
  Anna V. Mathew, Shinichi Okada, Anne- Emilie Decleves, and Kumar Sharma, American Diabetic Association 71st scientific Session, San Diego, CA, 1/1/2011
• Urinary metabalomic profile of Diabetic Nephropathy. Poster Presentation
  Anna V. Mathew, Satish P. Ramachandrarao, Joachim H. Ix, Ronghui Xu, Bruce A Barshop, Robert K Naviaux and Kumar Sharma, American Society of Nephrology, Denver, CO, 1/1/2010
• AMPK Mediates Early Diet-induced Effects on the Kidney. Poster Presentation
  Anne-Emilie Decleves, Maria Schenk, Anna V. Mathew and Kumar Sharma, International Society of Nephrology Nexus, Geneva, Switzerland, 1/1/2010
• Adiponectin deficient mice exhibit progressive diabetic kidney disease: possible role of AMPK. Poster Presentation
  Shinichi Okada, Anna V. Mathew and Kumar Sharma, International Society of Nephrology ISN Nexus Meeting, Japan, 1/1/2010
• Early podocyte changes in Adiponectin Knock out mice. Poster Presentation
  Anna V. Mathew, Shinichi Okada, Anne- Emilie Decleves, Krystyna Kudlicka, Marilyn Farquhar and Kumar Sharma, International Society of Nephrology Nexus, Japan, 1/1/2010
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Lectures

• Study design and sample collection in Metabolomics. 
  1/1/2014
• Preanalytical considerations in metabolomics study. 
  1/1/2013