BrianD.CromptonMD

PubMed

• 1 citations
  Mezigdomide is effective alone and in combination with menin inhibition in preclinical models of KMT2A-r and NPM1c AML.
  Wallace Bourgeois, Jevon A Cutler, Brandon J Aubrey, Daniela V Wenge, Florian Perner, Cynthia Martucci, Jill A Henrich, Kelly Klega, Radosław P Nowak, Katherine A Dono...> ;Blood. 2024 Apr 11
• Germline Genetic Testing and Survival Outcomes Among Children With Rhabdomyosarcoma: A Report From the Children's Oncology Group.
  Bailey A Martin-Giacalone, He Li, Michael E Scheurer, Dana L Casey, Shannon Dugan-Perez, Deborah A Marquez-Do, Donna Muzny, Richard A Gibbs, Donald A Barkauskas, David...> ;JAMA Network Open. 2024 Mar 4
• Genetic and epigenetic features of bilateral Wilms tumor predisposition in patients from the Children's Oncology Group AREN18B5-Q.
  Murphy, A., Cheng, C., Williams, J., Shaw, T., Pinto, E., Dieseldorff-Jones, K., Brzezinski, J., Renfro, L., Tornwall, B., Huff, V., Hong, A., Mullen, E., Crompton, B....> ;Nature Communications. 2023 Dec 18
• 10 citations
  Randomized Phase III Trial of Ganitumab With Interval-Compressed Chemotherapy for Patients With Newly Diagnosed Metastatic Ewing Sarcoma: A Report From the Children's ...
  Steven G DuBois, Mark D Krailo, Julia Glade-Bender, Allen Buxton, Nadia Laack, R Lor Randall, Helen X Chen, Nita L Seibel, Matthew Boron, Stephanie Terezakis, Christin...> ;Journal of Clinical Oncology. 2023 Apr 10
• 1 citations
  Clinical Targeted Next-Generation Panel Sequencing RevealsAmplification Is a Poor Prognostic Factor in Osteosarcoma.
  Amanda E Marinoff, Liam F Spurr, Christina Fong, Yvonne Y Li, Suzanne J Forrest, Abigail Ward, Duong Doan, Laura Corson, Audrey Mauguen, Navin Pinto, Luke Maese, Susan...> ;JCO Precision Oncology. 2023 Mar 1
• 1 citations
  Pilot Study of Recurrent Ewing's Sarcoma Management with Vigil/Temozolomide/Irinotecan and Assessment of Circulating Tumor (ct) DNA.
  Peter Anderson, Maurizio Ghisoli, Brian D Crompton, Kelly S Klega, Leonard H Wexler, Emily K Slotkin, Laura Stanbery, Luisa Manning, Gladice Wallraven, Meghan Manley, ...> ;Clinical Cancer Research. 2023 May 1
• 7 citations
  Circulating Tumor DNA Is Prognostic in Intermediate-Risk Rhabdomyosarcoma: A Report From the Children's Oncology Group.
  Samuel Abbou, Kelly Klega, Junko Tsuji, Mohammad Tanhaemami, David Hall, Donald A Barkauskas, Mark D Krailo, Carrie Cibulskis, Anwesha Nag, Aaron R Thorner, Samuel Pol...> ;Journal of Clinical Oncology. 2023 May 1
• 4 citations
  Tumor biology, biomarkers, and liquid biopsy in pediatric renal tumors.
  Amy L Walz, Mariana Maschietto, Brian Crompton, Nicholas Evageliou, David Dix, Godelieve Tytgat, Manfred Gessler, David Gisselsson, Najat C Daw, Jenny Wegert> ;Pediatric Blood & Cancer. 2023 May 1
• 9 citations
  Adverse prognostic impact of the loss of STAG2 protein expression in patients with newly diagnosed localised Ewing sarcoma: A report from the Children's Oncology Group.
  David S Shulman, Sonja Chen, David Hall, Anwesha Nag, Aaron R Thorner, Stephen L Lessnick, Kimberly Stegmaier, Katherine A Janeway, Steven G DuBois, Mark D Krailo, Don...> ;British Journal of Cancer. 2022 Dec 1
• 17 citations
  An international working group consensus report for the prioritization of molecular biomarkers for Ewing sarcoma.
  Shulman, D., Whittle, S., Surdez, D., Bailey, K., de Álava, E., Yustein, J., Shlien, A., Hayashi, M., Bishop, A., Crompton, B., DuBois, S., Shukla, N., Leavey, P., Les...> ;NPJ Precision Oncology. 2022 Sep 17
• 11 citations
  Phase 2 study of anti-disialoganglioside antibody, dinutuximab, in combination with GM-CSF in patients with recurrent osteosarcoma: A report from the Children's Oncolo...
  Pooja Hingorani, Mark Krailo, Allen Buxton, Paul Hutson, Paul M Sondel, Mitchell Diccianni, Alice Yu, Carol D Morris, Richard B Womer, Brian Crompton, R Lor Randall, L...> ;European Journal of Cancer. 2022 Sep 1
• Serrated Polyposis Syndrome in a Young Adolescent Patient.
  Victor L Fox, Inbar S Spofford, Brian D Crompton, Mathew B Yurgelun, Craig W Lillehei, Jeffrey D Goldsmith> ;Journal of Pediatric Gastroenterology and Nutrition. 2022 Sep 1
• 14 citations
  Molecular profiling identifies targeted therapy opportunities in pediatric solid cancer.
  Alanna J Church, Laura B Corson, Pei-Chi Kao, Alma Imamovic-Tuco, Deirdre Reidy, Duong Doan, Wenjun Kang, Navin Pinto, Luke Maese, Theodore W Laetsch, AeRang Kim, Susa...> ;Nature Medicine. 2022 Aug 1
• 2 citations
  Rapid and highly sensitive approach for multiplexed somatic fusion detection.
  Samuel Abbou, Sarah Finstuen-Magro, Brigit McDannell, Michelle Feenstra, Abigail Ward, David S Shulman, Birgit Geoerger, Joadly Duplan, Hannah Comeau, Katherine A Jane...> ;Modern Pathology. 2022 Aug 1
• 3 citations
  Circulating Tumor DNA Is Associated with Response and Survival in Patients with Advanced Leiomyosarcoma.
  Laura M Madanat-Harjuoja, Kelly Klega, Yao Lu, David S Shulman, Aaron R Thorner, Anwesha Nag, William D Tap, Denise K Reinke, Lisa Diller, Karla V Ballman, Suzanne Geo...> ;Clinical Cancer Research. 2022 Jun 13
• 14 citations
  Germline predisposition to pediatric Ewing sarcoma is characterized by inherited pathogenic variants in DNA damage repair genes.
  Riaz Gillani, Sabrina Y Camp, Seunghun Han, Jill K Jones, Hoyin Chu, Schuyler O'Brien, Erin L Young, Lucy Hayes, Gareth Mitchell, Trent Fowler, Alexander Gusev, Junne ...> ;American Journal of Human Genetics. 2022 Jun 2
• 5 citations
  Preclinical Modeling of Leiomyosarcoma Identifies Susceptibility to Transcriptional CDK Inhibitors through Antagonism of E2F-Driven Oncogenic Gene Expression.
  Matthew L Hemming, Patrick Bhola, Michael A Loycano, Justin A Anderson, Madeleine L Taddei, Leona A Doyle, Elizaveta Lavrova, Jessica L Andersen, Kelly S Klega, Morgan...> ;Clinical Cancer Research. 2022 Jun 1
• 13 citations
  Circulating Tumor DNA as a Biomarker in Patients With Stage III and IV Wilms Tumor: Analysis From a Children's Oncology Group Trial, AREN0533.
  Laura M Madanat-Harjuoja, Lindsay A Renfro, Kelly Klega, Brett Tornwall, Aaron R Thorner, Anwesha Nag, David Dix, Jeffrey S Dome, Lisa R Diller, Conrad V Fernandez, El...> ;Journal of Clinical Oncology. 2022 Sep 10
• 3 citations
  Patterns of Translocation Testing in Patients Enrolling to a Cooperative Group Trial for Newly Diagnosed Metastatic Ewing Sarcoma: A Report From the Children's Oncolog...
  Steven G. DuBois, Mark Krailo, Allen Buxton, Stephen L. Lessnick, Lisa A. Teot, Dinesh Rakheja, Brian D. Crompton, Katherine A. Janeway, Richard Gorlick, Julia Glade-B...> ;Archives of Pathology & Laboratory Medicine. 2021 Dec 1
• 37 citations
  STAG2 loss rewires oncogenic and developmental programs to promote metastasis in Ewing sarcoma.
  Biniam Adane, Gabriela Alexe, Bo Kyung A. Seong, Diana Lu, Elizabeth Hwang, Denes Hnisz, Caleb A. Lareau, Linda Ross, Shan Lin, Filemon S. Dela Cruz, Melissa Richardso...> ;Cancer Cell. 2021 Jun 14
• 8 citations
  Germline Sequencing Improves Tumor-Only Sequencing Interpretation in a Precision Genomic Study of Patients With Pediatric Solid Tumor.
  Jaclyn Schienda, Alanna J Church, Laura B Corson, Brennan Decker, Catherine M Clinton, Danielle K Manning, Alma Imamovic-Tuco, Deirdre Reidy, Gianna R Strand, Mark A A...> ;JCO Precision Oncology. 2021 Jan 1
• 2 citations
  Making the most of small samples: Optimization of tissue allocation of pediatric solid tumors for clinical and research use
  R. Seth Pinches, Catherine Clinton, Abigail Ward, Stephanie C. Meyer, Alyaa Al-Ibraheemi, Suzanne J. Forrest, Gianna R. Strand, Hillary Detert, Anne Piche-Schulman, Kr...> ;Pediatric Blood & Cancer. 2020 Sep 1
• 5 citations
  Chasing ctDNA in Patients With Sarcoma
  Catherine C. Coombs, Tony Dickherber, Brian D. Crompton> ;American Society of Clinical Oncology Educational Book. American Society of Clinical Oncology. Annual Meeting. 2020 Jun 29
• 4 citations
  Using Liquid Biopsy in the Treatment of Patient with OS.
  David S. Shulman, Brian D. Crompton> ;Advances in Experimental Medicine and Biology. 2020 Jan 1
• 74 citations
  Provocative questions in osteosarcoma basic and translational biology: A report from the Children's Oncology Group
  Ryan D. Roberts, Michael M. Lizardo, Damon R. Reed, Pooja Hingorani, Jason Glover, Wendy Allen-Rhoades, Timothy M. Fan, Chand Khanna, E. Alejandro Sweet-Cordero, Thoma...> ;Cancer. 2019 Oct 15
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Journal Articles

• Integrated Genetic and Pharmacologic Interrogation of Rare Cancers  
  Andrew L Hong, Katherine A Janeway, Brian D Crompton, Kimberly Stegmaier, Levi A Garraway, Alanna J Church, Stuart L Schreiber, William C Hahn, Nature