CatherineAnneO'BrienMD

PubMed

• 3 citations
  Assessing therapy response in patient-derived xenografts
  Janosch Ortmann, Ladislav Rampášek, Elijah Tai, Arvind Singh Mer, Ruoshi Shi, Erin L. Stewart, Celine Mascaux, Aline Fusco Fares, Nhu-An Pham, Gangesh Beri, Christophe...> ;Science Translational Medicine. 2021 Nov 17
• 29 citations
  CRISPR screens identify cholesterol biosynthesis as a therapeutic target on stemness and drug resistance of colon cancer.
  Shanshan Gao, Fraser Soares, Shiyan Wang, Chi Chun Wong, Huarong Chen, Zhenjie Yang, Weixin Liu, Minnie Y.Y. Go, Musaddeque Ahmed, Yong Zeng, Catherine A. O’Brien, Jos...> ;Oncogene. 2021 Oct 7
• 3 citations
  Publisher Correction: Epigenetic therapy induces transcription of inverted SINEs and ADAR1 dependency.
  Parinaz Mehdipour, Sajid A. Marhon, Ilias Ettayebi, Ankur Chakravarthy, Amir H. Hosseini, Yadong Wang, Fabíola Attié de Castro, Helen Loo Yau, Charles A. Ishak, Sagi A...> ;Nature. 2021 Mar 2
• 4 citations
  Adequacy of lymph node harvest following colectomy for obstructed and nonobstructed colon cancer
  Arash Azin, Dhruvin H. Hirpara, Arman Draginov, Mohammadali Khorasani, Sunil V. Patel, Catherine A. O’Brien, Fayez A. Quereshy, Sami A Chadi> ;Journal of Surgical Oncology. 2021 Feb 1
• 199 citations
  Colorectal Cancer Cells Enter a Diapause-like DTP State to Survive Chemotherapy
  Sumaiyah K. Rehman, Jennifer Haynes, Evelyne Collignon, Kevin R. Brown, Yadong Wang, Allison M.L. Nixon, Jeff Bruce, Jeff Wintersinger, Arvind Singh Mer, Edwyn B.L. Lo...> ;Cell. 2021 Jan 7
• 120 citations
  Epigenetic therapy induces transcription of inverted SINEs and ADAR1 dependency.
  Parinaz Mehdipour, Sajid A. Marhon, Ilias Ettayebi, Ankur Chakravarthy, Amir H. Hosseini, Yadong Wang, Fabíola Attié de Castro, Helen Loo Yau, Charles A. Ishak, Sagi A...> ;Nature. 2020 Oct 21
• 14 citations
  Optimizing the Care of Malignant Bowel Obstruction in Patients With Advanced Gynecologic Cancer
  Yeh Chen Lee, Nazlin Jivraj, Lisa Wang, Tanya P. Chawla, Jenny Lau, Jennifer Croke, Johane P. Allard, Terri Stuart-McEwan, Kashish Nathwani, Valerie Bowering, Katherin...> ;Journal of Oncology Practice. 2019 Sep 24
• 9 citations
  The impact of surgical modality on self-reported body image, quality of life and survivorship after anterior resection for colorectal cancer – a mixed methods study
  Dhruvin H. Hirpara, Arash Azin, Virginia Mulcahy, Emily Le Souder, Catherine A. O’Brien, Sami A Chadi, Fayez A. Quereshy> ;Canadian Journal of Surgery. Journal Canadien De Chirurgie. 2019 Aug 1
• 60 citations
  Safety and Feasibility of Using Magnetic Resonance Imaging Criteria to Identify Patients With "Good Prognosis" Rectal Cancer Eligible for Primary Surgery: The Phase 2 ...
  Erin D. Kennedy, Marko Simunovic, Kartik S Jhaveri, Richard Kirsch, J.D. Brierley, Sébastien Drolet, Carl J. Brown, Patrick M. Vos, Wei Xiong, Tony MacLean, Selliah Ka...> ;JAMA Oncology. 2019 Jul 1
• 59 citations
  VacA generates a protective intracellular reservoir for Helicobacter pylori that is eliminated by activation of the lysosomal calcium channel TRPML1
  Mariana Capurro, Laura Greenfield, Akriti Prashar, Sunny Xia, Majd Abdullah, Harikesh S. Wong, Xi Zoe Zhong, Nina Bertaux-Skeirik, Jayati Chakrabarti, Iram Siddiqui, C...> ;Nature Microbiology. 2019 May 20
• 29 citations
  Targeting bivalency de-represses Indian Hedgehog and inhibits self-renewal of colorectal cancer-initiating cells
  Evelyne Lima-Fernandes, Alex Murison, Tiago Medina, Yadong Wang, Anqi Ma, Cherry Leung, Genna M. Luciani, Jennifer Haynes, Aaron Pollett, Constanze Zeller, Shili Duan,...> ;Nature Communications. 2019 Mar 29
• 8 citations
  A rapid in vitro methodology for simultaneous target discovery and antibody generation against functional cell subpopulations.
  Allison M.L. Nixon, Alejandro Duque, Nicholas Yelle, Megan McLaughlin, Sadegh Davoudi, Nicolas M. Pedley, Jennifer Haynes, Kevin R. Brown, James Pan, Traver Hart, Penn...> ;Scientific Reports. 2019 Jan 29
• 476 citations
  Sensitive tumour detection and classification using plasma cell-free DNA methylomes
  Shu Yi Shen, Rajat Singhania, Gordon Fehringer, Ankur Chakravarthy, Michael H.A. Roehrl, Dianne Chadwick, Philip C. Zuzarte, Ayelet Borgida, Ting Ting Wang, Tiantian L...> ;Nature. 2018 Nov 14
• 9 citations
  Children with facial morphoea managing everyday life: a qualitative study.
  Elaine Stasiulis, Brenda Gladstone, Katherine M. Boydell, Catherine A. O’Brien, Elena Pope, R. M. Laxer> ;The British Journal of Dermatology. 2018 Aug 1
• 19 citations
  Malignant Bowel Obstruction in Advanced Gynecologic Cancers: An Updated Review from a Multidisciplinary Perspective.
  Yeh Chen Lee, Nazlin Jivraj, Catherine A. O’Brien, Tanya P. Chawla, Eran Shlomovitz, Sarah Buchanan, Jenny Lau, Jennifer Croke, Johane P. Allard, Preeti Dhar, Stephane...> ;Obstetrics and Gynecology International. 2018 May 17
• 49 citations
  Lactobacillus gasseri in the Upper Small Intestine Impacts an ACSL3-Dependent Fatty Acid-Sensing Pathway Regulating Whole-Body Glucose Homeostasis
  Paige V. Bauer, Frank A. Duca, T.M. Zaved Waise, Helen J. Dranse, Brittany A. Rasmussen, Akshita Puri, Mozhgan Rasti, Catherine A. O’Brien, Tony K.T. Lam> ;Cell Metabolism. 2018 Mar 6
• 15 citations
  Administration of Hypoxia-Activated Prodrug Evofosfamide after Conventional Adjuvant Therapy Enhances Therapeutic Outcome and Targets Cancer-Initiating Cells in Precli...
  Jennifer Haynes, Trevor D. McKee, Andrew Clayton Haller, Yadong Wang, Cherry Leung, Deena M.A. Gendoo, Evelyne Lima-Fernandes, Antonia Kreso, Robin Wolman, Eva Szentgy...> ;Clinical Cancer Research. 2018 Feb 23
• 161 citations
  Metformin Alters Upper Small Intestinal Microbiota that Impact a Glucose-SGLT1-Sensing Glucoregulatory Pathway.
  Paige V. Bauer, Frank A. Duca, T.M. Zaved Waise, Brittany A. Rasmussen, Mona A. Abraham, Helen J. Dranse, Akshita Puri, Catherine A. O’Brien, Tony K.T. Lam> ;Cell Metabolism. 2018 Jan 9
• 37 citations
  Protein kinase C δ signaling is required for dietary prebiotic-induced strengthening of intestinal epithelial barrier function.
  Richard Y. Wu, Majd Abdullah, Pekka Määttänen, Ana Victoria C. Pilar, Erin Scruten, Kathene C. Johnson-Henry, Scott Napper, Catherine A. O’Brien, Nicola L. Jones, Phil...> ;Scientific Reports. 2017 Jan 18
• 56 citations
  Comparison of clinical and economic outcomes between robotic, laparoscopic, and open rectal cancer surgery: early experience at a tertiary care center
  Karim M. Ramji, Michelle C. Cleghorn, Jonathan M. Josse, Andrea MacNeill, Catherine A. O’Brien, David R. Urbach, Fayez A. Quereshy> ;Surgical Endoscopy. 2016 Apr 1
• 17 citations
  In vitro and in vivo Limiting Dilution Assay for Colorectal Cancer.
  Lauren Agro, Catherine A. O’Brien> ;Bio-Protocol. 2015 Nov 20
• 33 citations
  KIT Signaling Promotes Growth of Colon Xenograft Tumors in Mice and Is Up-Regulated in a Subset of Human Colon Cancers.
  Evan C. Chen, Taylor A. Karl, Tomer Kalisky, Santosh Gupta, Catherine A. O’Brien, Teri A. Longacre, Matt van de Rijn, Stephen R. Quake, Michael F. Clarke, Michael E. R...> ;Gastroenterology. 2015 Sep 1
• 889 citations
  DNA-Demethylating Agents Target Colorectal Cancer Cells by Inducing Viral Mimicry by Endogenous Transcripts.
  David Roulois, Helen Loo Yau, Rajat Singhania, Yadong Wang, Arnavaz Danesh, Shu Yi Shen, Han Han, Gangning Liang, Peter A. Jones, Trevor J. Pugh, Catherine A. O’Brien,...> ;Cell. 2015 Aug 27
• 25 citations
  Resistance to dual blockade of the kinases PI3K and mTOR in KRAS-mutant colorectal cancer models results in combined sensitivity to inhibition of the receptor tyrosine...
  Peter J. Belmont, Ping Jiang, Trevor D. McKee, Tao Xie, Jason Isaacson, Nicole E. Baryla, Jatin Roper, Mark J. Sinnamon, Nathan V. Lee, Julie L.C. Kan, Oivin Guicherit...> ;Science Signaling. 2014 Nov 11
• 371 citations
  Self-renewal as a therapeutic target in human colorectal cancer
  Antonija Kreso, Peter van Galen, Nicholas M. Pedley, Evelyne Lima-Fernandes, Catherine Frelin, Thomas W. Davis, Liangxian Cao, Ramil Baiazitov, Wu Du, Nadiya Sydorenko...> ;Nature Medicine. 2014 Jan 1
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