CatherineJu-YingWuMD

PubMed

• Nonpathogenicengineered to surface display cytokines as a new platform for immunotherapy.
  Shaobo Yang, Michal Sheffer, Isabel E Kaplan, Zongqi Wang, Mubin Tarannum, Khanhlinh Dinh, Yasmin Abdulhamid, Roman Shapiro, Rebecca Porter, Robert Soiffer, Jerome Rit...> ;Research Square. 2024 Mar 22
• Fine tuning of CpG spatial distribution with DNA origami for improved cancer vaccination.
  Yang C Zeng, Olivia J Young, Christopher M Wintersinger, Frances M Anastassacos, James I MacDonald, Giorgia Isinelli, Maxence O Dellacherie, Miguel Sobral, Haiqing Bai...> ;Nature Nanotechnology. 2024 Mar 15
• CKLF instigates a "cold" microenvironment to promote MYCN-mediated tumor aggressiveness.
  Xiaodan Qin, Andrew Lam, Xu Zhang, Satyaki Sengupta, J Bryan Iorgulescu, Hongru Ni, Sanjukta Das, Madison Rager, Zhenwei Zhou, Tao Zuo, Grace K Meara, Alexander E Flor...> ;Science Advances. 2024 Mar 15
• Author Correction: The Cyclophilin A-CD147 complex promotes the proliferation and homing of multiple myeloma cells.
  Zhu, D., Wang, Z., Zhao, J., Calimeri, T., Meng, J., Hideshima, T., Fulciniti, M., Kang, Y., Ficarro, S., Tai, Y., Hunter, Z., McMilin, D., Tong, H., Mitsiades, C., Wu...> ;Nature Medicine. 2024 Jan 25
• The molecular map of CLL and Richter's syndrome.
  Amit Sud, Erin M Parry, Catherine J Wu> ;Seminars in Hematology. 2024 Jan 23
• Integrative genotyping of cancer and immune phenotypes by long-read sequencing.
  Livius Penter, Mehdi Borji, Adi Nagler, Haoxiang Lyu, Wesley S Lu, Nicoletta Cieri, Katie Maurer, Giacomo Oliveira, Aziz M Al'Khafaji, Kiran V Garimella, Shuqiang Li, ...> ;Nature Communications. 2024 Jan 2
• 2 citations
  Immune determinants of CAR-T cell expansion in solid tumor patients receiving GD2 CAR-T cell therapy.
  Sabina Kaczanowska, Tara Murty, Ahmad Alimadadi, Cristina F Contreras, Caroline Duault, Priyanka B Subrahmanyam, Warren Reynolds, Norma A Gutierrez, Reema Baskar, Cath...> ;Cancer Cell. 2024 Jan 8
• 1 citations
  DIISCO: A Bayesian framework for inferring dynamic intercellular interactions from time-series single-cell data.
  Cameron Park, Shouvik Mani, Nicolas Beltran-Velez, Katie Maurer, Satyen Gohil, Shuqiang Li, Teddy Huang, David A Knowles, Elham Azizi, Wu, C.> ;Biorxiv. 2023 Nov 16
• Predicting patient outcomes after treatment with immune checkpoint blockade: A review of biomarkers derived from diverse data modalities.
  Liu, Y., Altreuter, J., Bodapati, S., Cristea, S., Wong, C., Michor, F., Wu, C.> ;Cell Genomics. 2024 Jan 10
• 5 citations
  Latent human herpesvirus 6 is reactivated in CAR T cells.
  Caleb A Lareau, Yajie Yin, Katie Maurer, Katalin D Sandor, Bence Daniel, Garima Yagnik, José Peña, Jeremy Chase Crawford, Anne M Spanjaart, Jacob C Gutierrez, Nicholas...> ;Nature. 2023 Nov 1
• A multidimensional analysis reveals distinct immune phenotypes and tertiary lymphoid structure-like aggregates in the bone marrow of pediatric acute myeloid leukemia.
  Joost B Koedijk, Inge van der Werf, Livius Penter, Marijn A Vermeulen, Farnaz Barneh, Alicia Perzolli, Joyce I Meesters-Ensing, Marta Fiocco, Hester A de Groot-Krusema...> ;Medrxiv. 2023 Oct 30
• The BRD4-NUT Fusion Alone Drives Malignant Transformation of NUT Carcinoma.
  R Taylor Durall, Julianna Huang, Luke Wojenski, Yeying Huang, Prafulla C Gokhale, Brittaney A Leeper, Joshua O Nash, Pedro L Ballester, Scott Davidson, Adam Shlien, Em...> ;Cancer Research. 2023 Dec 1
• 3 citations
  ZNF683 marks a CD8T cell population associated with anti-tumor immunity following anti-PD-1 therapy for Richter syndrome.
  Parry, E., Lemvigh, C., Deng, S., Dangle, N., Ruthen, N., Knisbacher, B., Broséus, J., Hergalant, S., Guièze, R., Li, S., Zhang, W., Johnson, C., Long, J., Yin, S., We...> ;Cancer Cell. 2023 Oct 9
• 4 citations
  Hyperphosphorylation of BCL-2 family proteins underlies functional resistance to venetoclax in lymphoid malignancies.
  Stephen Jun Fei Chong, Fen Zhu, Olga Dashevsky, Rin Mizuno, Jolin Xh Lai, Liam Hackett, Christine E Ryan, Mary C Collins, J Bryan Iorgulescu, Romain Guièze, Johany Pen...> ;The Journal of Clinical Investigation. 2023 Nov 15
• Design of Cytotoxic T Cell Epitopes by Machine Learning of Human Degrons.
  Nicholas L Truex, Somesh Mohapatra, Mariane Melo, Jacob Rodriguez, Na Li, Wuhbet Abraham, Deborah Sementa, Faycal Touti, Derin B Keskin, Catherine J Wu, Darrell J Irvi...> ;Biorxiv. 2023 Sep 26
• Generation of mouse models carrying B cell restricted single or multiplexed loss-of-function mutations through CRISPR-Cas9 gene editing.
  Elisa Ten Hacken, Michaela Gruber, María Hernández-Sánchez, Gabriela Brunsting Hoffmann, Kaitlyn Baranowski, Robert A Redd, Kendell Clement, Kenneth Livak, Catherine J Wu> ;STAR Protocols. 2023 Dec 15
• 5 citations
  Preexisting tumor-resident T cells with cytotoxic potential associate with response to neoadjuvant anti-PD-1 in head and neck cancer.
  Oliveira, G., Egloff, A., Afeyan, A., Wolff, J., Zeng, Z., Chernock, R., Zhou, L., Messier, C., Lizotte, P., Pfaff, K., Stromhaug, K., Penter, L., Haddad, R., Hanna, G...> ;Science Immunology. 2023 Sep 8
• 5 citations
  Posttransplant cyclophosphamide vs tacrolimus-based GVHD prophylaxis: lower incidence of relapse and chronic GVHD.
  Katie Maurer, Vincent T Ho, Eno Inyang, Corey Cutler, John Koreth, Roman M Shapiro, Mahasweta Gooptu, Rizwan Romee, Sarah Nikiforow, Joseph H Antin, Catherine J Wu, Je...> ;Blood Advances. 2023 Aug 8
• 2 citations
  IGLV3-21R110 mutation has prognostic value in patients with treatment-naive chronic lymphocytic leukemia.
  Charlotte Syrykh, Berta Pons-Brun, Núria Russiñol, Heribert Playa-Albinyana, Tycho Baumann, Martí Duran-Ferrer, Marta Kulis, Anna Carbó-Meix, Pablo Mozas, Miguel Alcoc...> ;Blood Advances. 2023 Dec 12
• 2 citations
  SF3B1 mutation and ATM deletion codrive leukemogenesis via centromeric R-loop dysregulation.
  Martina Cusan, Haifeng Shen, Bo Zhang, Aijun Liao, Lu Yang, Meiling Jin, Mike Fernandez, Prajish Iyer, Yiming Wu, Kevyn Hart, Catherine Gutierrez, Sara Nik, Shondra M ...> ;The Journal of Clinical Investigation. 2023 Sep 1
• 1 citations
  Endocrine Therapy Synergizes with SMAC Mimetics to Potentiate Antigen Presentation and Tumor Regression in Hormone Receptor-Positive Breast Cancer.
  Francisco Hermida-Prado, Yingtian Xie, Shira Sherman, Zsuzsanna Nagy, Douglas Russo, Tara Akhshi, Zhengtao Chu, Avery Feit, Marco Campisi, Minyue Chen, Agostina Nardon...> ;Cancer Research. 2023 Oct 2
• 7 citations
  ALK peptide vaccination restores the immunogenicity of ALK-rearranged non-small cell lung cancer.
  Ines Mota, Enrico Patrucco, Cristina Mastini, Navin R Mahadevan, Tran C Thai, Elisa Bergaggio, Taek-Chin Cheong, Giulia Leonardi, Elif Karaca-Atabay, Marco Campisi, Te...> ;Nature Cancer. 2023 Jul 1
• Targeting conditioned media dependencies and FLT-3 in chronic lymphocytic leukemia.
  Salma Parvin, Aditi Aryal, Shanye Yin, Geoffrey G Fell, Matthew S Davids, Catherine J Wu, Anthony Letai> ;Blood Advances. 2023 Oct 10
• 10 citations
  Richter syndrome: novel insights into the biology of transformation.
  Erin M Parry, Elisa Ten Hacken, Catherine J Wu> ;Blood. 2023 Jul 6
• Cytokine release syndrome in haploidentical stem cell transplant may impact T-cell recovery and relapse.
  Roman M Shapiro, Haesook T Kim, Michela Ansuinelli, Indira Guleria, Corey S Cutler, John Koreth, Mahasweta Gooptu, Joseph H Antin, Amar Kelkar, Jerome Ritz, Catherine ...> ;Blood Advances. 2023 Aug 8
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Journal Articles

• A Cloning and Expression System to Probe T Cell Receptor Specificity and Assess Functional Avidity to Neoantigens  
  William J Lane, Patrick A Ott, Catherine J Wu, Donna E Leet, Blood

Abstracts/Posters

• Distinct Evolutionary Patterns in Chronic Lymphocytic Leukemia (CLL) during Resistance to Graft-Versus-Leukemia (GvL)
  Catherine J. Wu, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
• Deciphering the Role of Locally Disordered DNA Methylation on CLL Development In Vivo
  Catherine J. Wu, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
• T Cell Determinants of Response and Resistance to PD-1 Blockade in RichterÍs Transformation
  Catherine J. Wu, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• Clinical and Immunologic Activity of Ipilimumab Following Decitabine Priming in Post-Allogeneic Transplant and Transplant-Na¥ve Patients with Relapsed or Refractory My...
  Catherine J. Wu, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
• Spatial Genomic Heterogeneity in Chronic Lymphocytic Leukemia
  Catherine J. Wu, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
• B Cell Restricted Expression of Mutated IKZF3 modulates BCR Signaling and Homing Pathways in a Mouse Model of CLL
  Catherine J. Wu, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• Interrogation of Individual CLL Loss-of-Function Lesions By CRISPR In Vivo Editing Reveals Common and Unique Pathway Alterations
  Catherine J. Wu, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• Lineage Tracing in Chronic Lymphocytic Leukemia Reveals Clones with Stable Gene Expression States That Differentially Respond to Therapy
  Catherine J. Wu, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
• Identification of Genotype-Specific Therapeutic Vulnerabilities By Comparative Dynamic BH3 Profiling Analysis of Human and Murine CLL
  Catherine J. Wu, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• MCL-1 and PKA/AMPK Axis Fuel Venetoclax Resistance in Lymphoid Cancers
  Catherine J. Wu, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
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Lectures

• Genome Editing for Transplantation and Cellular Therapies 
  61st Annual American Society of Hematology Meeting - Orlando, FL - 12/7/2019
• Response Comes of Age in Chronic Lymphocytic Leukemia 
  61st Annual American Society of Hematology Meeting - Orlando, FL - 12/7/2019
• Continuing Conversations With the Speakers on Genome Editing for Transplantation and Cellular Therapies 
  61st Annual American Society of Hematology Meeting - Orlando, FL - 12/7/2019
• Clonal Dynamics in Chronic Lymphocytic Leukemia 
  61st Annual American Society of Hematology Meeting - Orlando, FL - 12/7/2019
• Multimodal Single-Cell Profiling Defines the Epigenetic Determinants of Chronic Lymphocytic Leukemia Evolution 
  2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
• A Clinical Trial of the STAT3 Inhibitor Pyrimethamine in Chronic Lymphocytic Leukemia 
  2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
• Integration of Immunotherapy Into Treatment for Hematologic Malignancies 
  60th American Society of Hematology Annual Meeting - 11/30/2018
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