ChristopherJamesMD

PubMed

• 8 citations
  De novo purine biosynthesis is a major driver of chemoresistance in glioblastoma
  Jack Shireman, Fatemeh Atashi, Gina Lee, Eunüs S. Ali, Miranda R. Saathoff, Cheol Park, Sol Savchuk, Shivani Baisiwala, Jason Miska, Maciej S. Lesniak, C. David James,...> ;Brain. 2021 May 7
• 33 citations
  Mesenchymal Stem Cells Successfully Deliver Oncolytic Virotherapy to Diffuse Intrinsic Pontine Glioma.
  Michael Chastkofsky, Katarzyna C. Pituch, Hiroaki Katagi, Markella Zannikou, Liliana Ilut, Ting Xiao, Yu Han, Adam M. Sonabend, David T. Curiel, Erin R. Bonner, Javad ...> ;Clinical Cancer Research. 2021 Mar 15
• 103 citations
  A first-in-human phase 0 clinical study of RNA interference-based spherical nucleic acids in patients with recurrent glioblastoma.
  Priya Kumthekar, Caroline H. Ko, Tatjana Paunesku, Karan Dixit, Adam M. Sonabend, Orin Bloch, Matthew C. Tate, Margaret Schwartz, Laura Zuckerman, Ray Lezon, Rimas V. ...> ;Science Translational Medicine. 2021 Mar 10
• 12 citations
  Neural stem cells secreting bispecific T cell engager to induce selective antiglioma activity
  Katarzyna C. Pituch, Markella Zannikou, Liliana Ilut, Ting Xiao, Michael Chastkofsky, Madina Sukhanova, Nicola Bertolino, Daniele Procissi, Christina Amidei, Craig Hor...> ;Proceedings of the National Academy of Sciences of the United States of America. 2021 Mar 2
• 9 citations
  Heparan sulfate synthesized by Ext1 regulates receptor tyrosine kinase signaling and promotes resistance to EGFR inhibitors in GBM.
  Yuki Ohkawa, Anna Wade, Olle R. Lindberg, Katharine Chen, Vy M. Tran, Spencer Brown, Anupam Kumar, Mausam Kalita, C. David James, Joanna J. Phillips> ;Molecular Cancer Research. 2021 Jan 1
• 73 citations
  Ultrasound-mediated Delivery of Paclitaxel for Glioma: A Comparative Study of Distribution, Toxicity, and Efficacy of Albumin-bound Versus Cremophor Formulations
  Daniel Y Zhang, Crismita Dmello, Li Chen, Víctor A. Arrieta, Edgar Gonzalez-Buendia, J. Robert Kane, Lisa P. Magnusson, Aneta Baran, C. David James, Craig Horbinski, A...> ;Clinical Cancer Research. 2020 Jan 15
• 52 citations
  SRSF3-Regulated RNA Alternative Splicing Promotes Glioblastoma Tumorigenicity by Affecting Multiple Cellular Processes
  Xiao Song, Xuechao Wan, Tianzhi Huang, Chang Zeng, Namratha Sastry, Bingli Wu, C. David James, Craig Horbinski, Ichiro Nakano, Wei Zhang, Bo Hu, Shi Yuan Cheng> ;Cancer Research. 2019 Oct 15
• 9 citations
  Mechanisms of Resistance to EGFR Inhibition Reveal Metabolic Vulnerabilities in Human GBM
  Andrew McKinney, Olle R. Lindberg, Jane R. Engler, Katharine Chen, Anupam Kumar, Henry Gong, Kan V. Lu, Erin F. Simonds, Timothy F. Cloughesy, Linda M. Liau, Michael D...> ;Molecular Cancer Therapeutics. 2019 Sep 1
• 16 citations
  Identification of novel RAS signaling therapeutic vulnerabilities in Diffuse Intrinsic Pontine Gliomas
  Robert F. Koncar, Brittany Dey, Ann Catherine J. Stanton, Nishant Agrawal, Michelle Wassell, Lauren McCarl, Abigail L. Locke, Lauren Sanders, Olena Morozova-Vaske, Max...> ;Cancer Research. 2019 Aug 15
• 108 citations
  Glioblastoma-Derived IL6 Induces Immunosuppressive Peripheral Myeloid Cell PD-L1 and Promotes Tumor Growth
  Jonathan B. Lamano, Jason B. Lamano, Yuping D. Li, Joseph D. DiDomenico, Winward Choy, Dorina Veliceasa, Daniel E. Oyon, Shayan Fakurnejad, Leonel Ampie, Kartik Kesava...> ;Clinical Cancer Research. 2019 Jun 15
• 9 citations
  High density is a property of slow-cycling and treatment-resistant human glioblastoma cells
  Hanna Sabelström, David A. Quigley, Daniel J. Foster, Clara A.M. Fuchshuber, Edith Yuan, Nan Li, Francesca Paterno, Joanna J. Phillips, C. David James, Börje Norling, ...> ;Experimental Cell Research. 2019 May 1
• Tenascin-C expression contributes to pediatric brainstem glioma tumor phenotype and represents a novel biomarker of disease.
  Qi, J.,Esfahani, D. R.,Huang, T.,Ozark, P.,Bartom, E.,Hashizume, R.,Bonner, E. R.,An, S.,Horbinski, C. M.,James, C. D.,Saratsis, A. M.> ;Acta Neuropathol Commun. 2019 May 17
• 50 citations
  Activation of Dopamine Receptor 2 Prompts Transcriptomic and Metabolic Plasticity in Glioblastoma
  Jack Shireman, Mei Huang, Jason Miska, Fatemeh Atashi, Shivani Baisiwala, Cheol Hong Park, Miranda R. Saathoff, Louisa Warnke, Ting Xiao, Maciej S. Lesniak, C. David J...> ;The Journal of Neuroscience. 2019 Mar 13
• 48 citations
  Interleukin-8/CXCR2 signaling regulates therapy-induced plasticity and enhances tumorigenicity in glioblastoma.
  Tanwir Hasan, Jack Shireman, Cheol Park, Fatemeh Atashi, Shivani Baisiwala, Gina Lee, Donna Guo, Jennifer Y. Wang, Mahua Dey, Meijing Wu, Maciej S. Lesniak, Craig Horb...> ;Cell Death & Disease. 2019 Mar 29
• 48 citations
  Cytomegalovirus promotes murine glioblastoma growth via pericyte recruitment and angiogenesis
  Harald Krenzlin, Prajna Behera, Viola Lorenz, Carmela Passaro, Mykola Zdioruk, Michał Nowicki, Korneel Grauwet, Hong Zhang, Magdalena Skubal, Hirotaka Ito, Rachel Zane...> ;The Journal of Clinical Investigation. 2019 Apr 1
• 29 citations
  Methylation-dependent Tissue Factor Suppression Contributes to the Reduced Malignancy of IDH1-mutant Gliomas
  Dusten Unruh, Snezana Mirkov, Brian Wray, Michael Drumm, Jonathan B. Lamano, Yuping D. Li, Qazi F Haider, Rodrigo Javier, Kathleen McCortney, Amanda Saratsis, Denise M...> ;Clinical Cancer Research. 2019 Jan 15
• 86 citations
  MIR93 (microRNA -93) regulates tumorigenicity and therapy response of glioblastoma by targeting autophagy
  Tianzhi Huang, Xuechao Wan, Angel Alvarez, C. David James, Xiao Song, Yongyong Yang, Namratha Sastry, Ichiro Nakano, Erik P. Sulman, Bo Hu, Shi Yuan Cheng> ;Autophagy. 2019 Jan 31
• 10 citations
  Measuring Tumor Metabolism in Pediatric Diffuse Intrinsic Pontine Glioma Using Hyperpolarized Carbon-13 MR Metabolic Imaging
  Adam Autry, Rintaro Hashizume, C. David James, Peder E. Z. Larson, Daniel B. Vigneron, Ilwoo Park> ;Contrast Media & Molecular Imaging. 2018 Jul 30
• 20 citations
  Modeling the diffusion of D-2-hydroxyglutarate from IDH1 mutant gliomas in the central nervous system.
  Andreas A. Linninger, Grant Hartung, Benjamin P. Liu, Snezana Mirkov, Kevin Tangen, Rimas V. Lukas, Dusten Unruh, C. David James, Jann N. Sarkaria, Craig Horbinski> ;Neuro-Oncology. 2018 Aug 2
• 69 citations
  Phase-2 trial of palbociclib in adult patients with recurrent RB1-positive glioblastoma.
  Jennie Taylor, Mili Parikh, Joanna J. Phillips, C. David James, Annette M. Molinaro, Nicholas Butowski, Jennifer Clarke, Nancy Ann Oberheim-Bush, Susan M. Chang, Mitch...> ;Journal of Neuro-Oncology. 2018 Aug 27
• 122 citations
  IDO1 Inhibition Synergizes with Radiation and PD-1 Blockade to Durably Increase Survival Against Advanced Glioblastoma
  Erik Ladomersky, Lijie Zhai, Alicia Lenzen, Kristen L. Lauing, Jun Qian, Denise M. Scholtens, Galina Gritsina, Xuebing Sun, Ye Liu, Fenglong Yu, Wenfeng Gong, Yong Liu...> ;Clinical Cancer Research. 2018 Jun 1
• 28 citations
  Genome-wide methylomic and transcriptomic analyses identify subtype-specific epigenetic signatures commonly dysregulated in glioma stem cells and glioblastoma.
  Rajendra P. Pangeni, Zhou Zhang, Angel Alvarez, Xuechao Wan, Namratha Sastry, Songjian Lu, Taiping Shi, Tianzhi Huang, Charles X. Lei, C. David James, John A. Kessler,...> ;Epigenetics. 2018 Aug 6
• 25 citations
  Differential Response of Glioma Stem Cells to Arsenic Trioxide Therapy Is Regulated by MNK1 and mRNA Translation.
  Jonathan B. Bell, Frank Eckerdt, Harshil Dhruv, Darren Finlay, Sen Peng, Seungchan Kim, Barbara Kroczynska, Elspeth M. Beauchamp, Kristen Alley, Jessica Clymer, Stewar...> ;Molecular Cancer Research. 2018 Jan 1
• 28 citations
  Combination Treatment with the GSK-3 Inhibitor 9-ING-41 and CCNU Cures Orthotopic Chemoresistant Glioblastoma in Patient-Derived Xenograft Models.
  Andrey Ugolkov, Wenan Qiang, Gennadiy Bondarenko, Daniel Procissi, Irina N. Gaisina, C. David James, James P. Chandler, Alan P. Kozikowski, Hendra Gunosewoyo, Thomas V...> ;Translational Oncology. 2017 Aug 1
• 136 citations
  Cancer-Associated IDH1 Promotes Growth and Resistance to Targeted Therapies in the Absence of Mutation
  Andrea E. Calvert, Alexandra Chalastanis, Yongfei Wu, Lisa A. Hurley, Fotini M. Kouri, Yingtao Bi, Maureen Kachman, Jasmine L. May, Elizabeth T. Bartom, Youjia Hua, Ra...> ;Cell Reports. 2017 May 30
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