
Craig J McClain MD
Hepatology & Liver Transplantation
Professor of Medicine, University Louisville School of Medicine
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401 E Chestnut StSuite 310Louisville, KY 40202
Phone+1 502-584-8563
Fax+1 502-562-6196
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Education & Training
University of MinnesotaFellowship, Gastroenterology, 1975 - 1977
UPMC Medical EducationResidency, Internal Medicine, 1972 - 1975
University of Tennessee Health Science Center College of MedicineClass of 1972
Earlham CollegeBA, 1968
Certifications & Licensure
KY State Medical License 1982 - 2027
OH State Medical License 2005 - 2006
MN State Medical License 1976 - 1982
PA State Medical License 1973 - 1976
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Gastroenterology
Awards, Honors, & Recognition
- CMS Meaningful Use Stage 1 Certification Allscripts FollowMyHealth, Allscripts, 2015-2017
- CMS Meaningful Use Stage 2 Certification Allscripts FollowMyHealth, Allscripts, 2015-2017
- CMS Meaningful Use Stage 2 Certification Allscripts Enterprise EHR, Allscripts, 2015-2017
Clinical Trials
- Efficacy Study of Anakinra, Pentoxifylline, and Zinc Compared to Methylprednisolone in Severe Acute Alcoholic Hepatitis Start of enrollment: 2013 Sep 01
- Novel Therapies in Moderately Severe Acute Alcoholic Hepatitis Start of enrollment: 2013 Aug 01
- Trial of Anakinra (Plus Zinc) or Prednisone in Patients With Severe Alcoholic Hepatitis Start of enrollment: 2020 Jul 10
Publications & Presentations
PubMed
- Mean Arterial Pressure at Admission Predicts 28-day Mortality in Patients with Severe Alcohol-associated Hepatitis.Meritxell Ventura-Cots, Ana Clemente, Edilmar Alvarado-Tapias, Sujan Ravi, Berta Cuyas
Clinical and Translational Gastroenterology. 2026-06-03 - 3 citationsNatural history and development of a novel composite endpoint in patients with alcohol-associated hepatitis: Data from a prospective multicenter study.Srinivasan Dasarathy, Wanzhu Tu, Nicole Welch, Samer Gawrieh, Yunpeng Yu
Hepatology. 2026-06-01 - 2 citationsPilot trials of oral betaine in participants with metabolic dysfunction-associated steatotic liver disease and elevated alanine aminotransferase.Andrew S Lim, Sheena N Cruz, Aliya Asghar Uddin, Olga Malysheva, Marie A Caudill
Hepatology. 2026-06-01
Journal Articles
- Copper-Fructose Interactions: A Novel Mechanism in the Pathogenesis of NAFLDMiriam B Vos, Craig J McClain, MDPI
- Nutrition in Patients with CirrhosisCraig McClain, MD, National Institutes of Health
- Simultaneous Quantification of Straight-Chain and Branched-Chain Short Chain Fatty Acids by Gas Chromatography Mass SpectrometryCraig McClain, Craig McClain, ScienceDirect
Books/Book Chapters
Abstracts/Posters
- Special Topic Issue: Liver and Pancreatic Diseases: Consequences of Chronic Alcoholic ConsumptionSinger MV, Dooley S, McClain CJ, Zakhari S, Dig Dis, Falk Workshop, Freiburg, 1/1/2010
- National Consensus Counsel on OTC AnalgesicsMcClain CJ, Ft. Lauderdale, Florida, 1/1/1993
- International Cytokine Research ConferenceMcClain CJ, Hilton Head, SC, 1/1/1987
Press Mentions
Still Asking Questions: ULSOM Faculty Dr. Craig McClain Never Stops LearningJuly 29th, 2025
ACG Guideline Embraces ‘Global Concept’ of Malnutrition in Liver DiseaseMay 2nd, 2025
UofL and Robley Rex VA Medical Center Partnership Leads to New State-of-the-Art Multiphoton Microscopes for Exposure StudiesNovember 22nd, 2022
Grant Support
- Integrated therapies for alcohol use and ALD (ITAALD) Network -UofL Clinical CenterUNIVERSITY OF LOUISVILLE2018–2029
- Inflammation Resolving Lipid Mediators: Novel Therapy for Alcohol AssociatedLiver DiseaseLOUISVILLE VA MEDICAL MEDICAL CENTER2023–2027
- Hepatobiology and Toxicology COBREUNIVERSITY OF LOUISVILLE2016–2026
- The Role of Nutrition in the Development/Progression of Alcohol-Induced Organ InjuryUNIVERSITY OF LOUISVILLE2016–2026
- Alcohol, Proteasome Dysfunction In Liver InjuryVeterans Affairs2011–2012
Professional Memberships
- Fellow
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