DavidFisherMD

PubMed

• Functional genomics of human clear cell sarcoma: genomic, transcriptomic and chemical biology landscape for clear cell sarcoma.
  Samuel V Rasmussen, Agnieszka Wozniak, Melvin Lathara, Joshua M Goldenberg, Benjamin M Samudio, Lissett R Bickford, Kiyo Nagamori, Hollis Wright, Andrew D Woods, Shefa...> ;British Journal of Cancer. 2023 May 1
• 28 citations
  NRF2 activation induces NADH-reductive stress, providing a metabolic vulnerability in lung cancer.
  Tommy Weiss-Sadan, Maolin Ge, Makiko Hayashi, Magdy Gohar, Cong-Hui Yao, Adriaan de Groot, Stefan Harry, Alexander Carlin, Hannah Fischer, Lei Shi, Ting-Yu Wei, Charle...> ;Cell Metabolism. 2023 Mar 7
• 6 citations
  Discovery of Targets for Immune-Metabolic Antitumor Drugs Identifies Estrogen-Related Receptor Alpha.
  Avinash Sahu, Xiaoman Wang, Phillip Munson, Jan P G Klomp, Xiaoqing Wang, Shengqing Stan Gu, Ya Han, Gege Qian, Phillip Nicol, Zexian Zeng, Chenfei Wang, Collin Tokhei...> ;Cancer Discovery. 2023 Mar 1
• 5 citations
  β-Endorphin mediates radiation therapy fatigue.
  Andrea L Hermann, Gillian L Fell, Lajos V Kemény, Claire Y Fung, Kathryn D Held, Peter J Biggs, Phillip D Rivera, Staci D Bilbo, Vivien Igras, Henning Willers, Jong Ku...> ;Science Advances. 2022 Dec 16
• 35 citations
  Adjuvant Chemotherapy for Muscle-invasive Bladder Cancer: A Systematic Review and Meta-analysis of Individual Participant Data from Randomised Controlled Trials
  Sarah Burdett, David Fisher, Claire L Vale, Aldo V. Bono, Noel W. Clarke, Francesco Cognetti, Laurence Collette, Richard J. Cote, Peter J. Goebell, Susan Groshen, Jan ...> ;European Urology. 2021 Nov 19
• 24 citations
  SOX10 regulates melanoma immunogenicity through an IRF4-IRF1 axis.
  Satoru Yokoyama, Atsushi Takahashi, Ryota Kikuchi, Soshi Nishibu, Jennifer A. Lo, Miroslav Hejna, Wooyoung M. Moon, Shinichiro Kato, Yue Zhou, F. Stephen Hodi, Jun S. ...> ;Cancer Research. 2021 Nov 2
• 6 citations
  G9a: An Emerging Epigenetic Target for Melanoma Therapy
  Jessica L Flesher, David E. Fisher> ;Epigenomes. 2021 Oct 12
• MFN2 Stabilization: A Bridge for Endoplasmic Reticulum Stress Sensitivity in Melanoma
  Charles H. Adelmann, Inbal Rachmin, David E. Fisher> ;The Journal of Investigative Dermatology. 2021 Sep 23
• 40 citations
  Inhibition of WEE1 Is Effective in TP53- and RAS-Mutant Metastatic Colorectal Cancer: A Randomized Trial (FOCUS4-C) Comparing Adavosertib (AZD1775) With Active Monitoring
  J. Seligmann, David Fisher, Louise Brown, Richard Adams, Janet Graham, Philip Quirke, S. Richman, Rachel Butler, Enric Domingo, Andrew Blake, Michael Braun, F. Collins...> ;Journal of Clinical Oncology. 2021 Sep 18
• 13 citations
  Capecitabine Versus Active Monitoring in Stable or Responding Metastatic Colorectal Cancer After 16 Weeks of First-Line Therapy: Results of the Randomized FOCUS4-N Trial
  Richard Adams, David Fisher, Janet Graham, Jenny F. Seligmann, Matthew T. Seymour, Richard Kaplan, Emma Yates, Mahesh K. B. Parmar, Susan D. Richman, Philip Quirke, Ra...> ;Journal of Clinical Oncology. 2021 Sep 13
• 13 citations
  Association between time-to-treatment and outcomes in non-small cell lung cancer: a systematic review.
  H. Hall, Adam Tocock, Sarah Burdett, David Fisher, William Ricketts, John Robson, Thomas Round, Sarita Gorolay, Emma MacArthur, Donna Chung, Sam M. Janes, Michael D Pe...> ;Thorax. 2021 Aug 17
• Authors' reply to "Comments on Identifying inconsistency in network meta-analysis: Is the net heat plot a reliable method?"
  Suzanne C Freeman, David Fisher, Ian R. White, James R. Carpenter> ;Statistics in Medicine. 2021 Aug 15
• 407 citations
  Association Between Administration of IL-6 Antagonists and Mortality Among Patients Hospitalized for COVID-19: A Meta-analysis.
  Manu Shankar-Hari, Claire L Vale, Peter J. Godolphin, David Fisher, Higgins Jpt., Francesca Spiga, Jelena Savović, Jayne F. Tierney, Gabriel Baron, Julie Benbenishty, ...> ;JAMA. 2021 Aug 10
• 32 citations
  NNT mediates redox-dependent pigmentation via a UVB- and MITF-independent mechanism.
  Jennifer Allouche, Inbal Rachmin, Kaustubh Adhikari, Luba M. Pardo, Ju Hee Lee, Alicia M. McConnell, Shinichiro Kato, Shaohua Fan, Akinori Kawakami, Yusuke Suita, Kazu...> ;Cell. 2021 Aug 5
• 10 citations
  Molecular subtype-specific efficacy of anti-EGFR therapy in colorectal cancer is dependent on the chemotherapy backbone.
  Sanne ten Hoorn, Dirkje W. Sommeijer, Faye Elliott, David Fisher, Tim R. de Back, Anne Trinh, Lianne Koens, Tim Maughan, Jenny F. Seligmann, Matthew T. Seymour, Phil Q...> ;British Journal of Cancer. 2021 Jul 12
• 15 citations
  Vitamin D deficiency exacerbates UV/endorphin and opioid addiction.
  Lajos Kemény, Kathleen C. Robinson, Andrea L. Hermann, Deena M. Walker, Susan Regan, Yik Weng Yew, Yi Chun Lai, Nicholas Theodosakis, Phillip D. Rivera, Weihua Ding, L...> ;Science Advances. 2021 Jun 11
• 7 citations
  Treatment breaks in first line treatment of advanced colorectal cancer: An individual patient data meta-analysis.
  Richard Adams, Kaitlyn K.H. Goey, Benoist Chibaudel, Miriam Koopman, Cornelis J A Punt, Dirk Arnold, Axel Hinke, Susanna Hegewisch-Becker, Aimery de Gramont, Roberto L...> ;Cancer Treatment Reviews. 2021 May 19
• 17 citations
  A framework for prospective, adaptive meta-analysis (FAME) of aggregate data from randomised trials
  Jayne F. Tierney, David Fisher, Claire L Vale, Sarah Burdett, Larysa Rydzewska, Ewelina Rogozińska, Peter J. Godolphin, Ian R. White, Mahesh K. B. Parmar> ;Plos Medicine. 2021 May 6
• 63 citations
  Skin pigmentation and its control: From ultraviolet radiation to stem cells
  Joseph Michael Yardman-Frank, David E. Fisher> ;Experimental Dermatology. 2021 Apr 1
• 6 citations
  Reduced MC4R signaling alters nociceptive thresholds associated with red hair.
  Kathleen C. Robinson, Lajos Kemény, Gillian L. Fell, Andrea L. Hermann, Jennifer Allouche, Weihua Ding, Ajay S. Yekkirala, Jennifer J. Hsiao, Mack Y. Su, Nicholas Theo...> ;Science Advances. 2021 Apr 1
• 5 citations
  Melanocortin 1 receptor is dispensable for acute stress induced hair graying in mice.
  Bing Zhang, Megan He, Inbal Rachmin, Xiaoling Yu, Seungtea Kim, David E. Fisher, Ya-Chieh Hsu> ;Experimental Dermatology. 2021 Apr 1
• 10 citations
  CYP27A1-dependent anti-melanoma activity of limonoid natural products targets mitochondrial metabolism.
  Hyelim Cho, Qiong Shen, Lydia H. Zhang, Mikiko Okumura, Akinori Kawakami, Jessi Ambrose, Frederic Sigoillot, Howard R Miller, Scott Gleim, Amanda Cobos-Correa, Ying Wa...> ;Cell Chemical Biology. 2021 Mar 31
• 10 citations
  Stress-associated ectopic differentiation of melanocyte stem cells and ORS amelanotic melanocytes in an ex vivo human hair follicle model.
  Inbal Rachmin, Ju Hee Lee, Bing Zhang, James Sefton, Inhee Jung, Young In Lee, Ya-Chieh Hsu, David E. Fisher> ;Experimental Dermatology. 2021 Apr 1
• 47 citations
  Epitope spreading toward wild-type melanocyte-lineage antigens rescues suboptimal immune checkpoint blockade responses
  Jennifer A. Lo, Masayoshi Kawakubo, Vikram R. Juneja, Mack Y. Su, Tal Hadad Erlich, Martin W. LaFleur, Lajos Kemény, Mamunur Rashid, Mohsen Malehmir, S. Alireza Rabi, ...> ;Science Translational Medicine. 2021 Feb 17
• 28 citations
  Biology of Melanoma.
  Stephen M. Ostrowski, David E. Fisher> ;Hematology/oncology Clinics of North America. 2021 Feb 1
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Journal Articles

• Protection from UV Light Is an Evolutionarily Conserved Feature of the Haematopoietic Niche  
  David E Fisher, John M Gansner, Leonard I Zon, Nature