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Devraj Basu, MD, Otolaryngology (ENT), Philadelphia, PA

DevrajBasuMDPhD, FACS

Otolaryngology (ENT) Philadelphia, PA

Head & Neck Microvascular Surgery, Head & Neck Oncologic Surgery

Associate Professor, Otorhinolaryngology/Head & Neck Surgery, Perelman School of Medicine

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  • I see patients at the Hospital of the University of Pennsylvania, where I am an Associate Professor with 11 years of experience as an oncologic and reconstructive surgeon. I use open, endoscopic, robotic, and laser procedures to treat neoplasms of the larynx, pharynx, oral cavity, nasal cavity, paranasal sinuses, salivary glands, parapharyngeal space, and skin. I am also experienced in thyroid and parathyroid surgery.

    My research group focuses on squamous cell carcinomas of the head and neck, with emphasis on the rapidly growing HPV+ subtype of this disease. This NIH-funded work seeks to address show cancers evade therapy by exploiting aspects of normal human development and devises strategies to improve drug responses by modulating the developmental plasticity inherent in malignant cells. In doing so, our goals are to increase survival for the worst head and neck cancers and alter management for readily curable ones in order to abate treatment toxicity. My dual clinical and scientific roles drive optimal research use of resected cancers to serve these long-term goals.

Education & Training

  • The Wistar Institute
    The Wistar InstitutePost-Doctoral Fellowship, Cancer Biology, 2007 - 2012
  • University of Pennsylvania Health System
    University of Pennsylvania Health SystemFellowship, Head & Neck Surgical Oncology/Microvascular Reconstruction, 2006 - 2007
  • Washington University/B-JH/SLCH Consortium
    Washington University/B-JH/SLCH ConsortiumResidency, Otolaryngology - Head and Neck Surgery, 2002 - 2006
  • Washington University/B-JH/SLCH Consortium
    Washington University/B-JH/SLCH ConsortiumInternship, Otolaryngology - Head and Neck Surgery, 2001 - 2002
  • Washington University in St. Louis School of Medicine
    Washington University in St. Louis School of MedicineClass of 2001
  • Washington University in St. Louis
    Washington University in St. LouisPh.D., Immunology, 2001
  • Brown University
    Brown UniversitySc.B., Biology, magna cum laude, 1990 - 1994
  • Brown University
    Brown UniversityBS, Biology, Magna Cum Laude, 1994

Certifications & Licensure

  • MO State Medical License
    MO State Medical License 2004 - 2025
  • PA State Medical License
    PA State Medical License 2006 - 2024
  • American Board of Otolaryngology - Head and Neck Surgery Otolaryngology

Awards, Honors, & Recognition

  • Member American Head and Neck Society
  • Fellow Triological Society
  • Member American Association for Cancer Research
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Clinical Trials

Publications & Presentations


Journal Articles

  • IL-6 mediates cross-talk between activated fibroblasts and tumor cells in the tumor microenvironment  
    Karakasheva TA, Lin EW, Tang Q, Qiao E, Waldron TJ, Soni M, Klein-Szanto AJ, Sahu V, Basu D, Ohashi S, Baba K, Giaccone ZT, Walker SR, Frank DA, Wileyto EP, Long Q, Du..., Cancer Research, 1/1/2018
  • Shear Wave Elastography in the Evaluation of Thyroid Nodules and Correlation with Aggressive Features on Microscopy: A Case Report  
    Chen DW,1 Horst J, Basu D, Dalal S, Jhala D, Hyland KA, Consultant360, 1/1/2018
  • IL-6 Mediates Cross-Talk Between Activated Fibroblasts and Tumor Cells in the Tumor Microenvironment  
    Devraj Basu, Eric W Lin, Clinical Cancer Research
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Books/Book Chapters


  • Identifying adverse molecular features of HPV+ head and neck cancers using patient-derived models. 
    2019 ASCO Annual Meeting - 6/1/2019
  • Genetic Determinants of PDX Growth in HPV+ Head and Neck Cancer 
    Scottsdale, AZ - 1/1/2018
  • Leveraging patient-derived models of HPV+ head and neck cancer 
    Virginia Commonwealth University School of Dentistry, Richmond, VA - 1/1/2018
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Press Mentions

  • Recipients of AACR Research Funding & Fellowships 1993–2017
    Recipients of AACR Research Funding & Fellowships 1993–2017September 8th, 2017

Professional Memberships