EllenNSpremulliMD

Oncology • Anniston, AL

Physician

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Office
901 Leighton Ave
Suite 602
Anniston, AL 36207
Phone+1 256-238-1011

Fax+1 256-238-4366
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Education & Training

SUNY Health Science Center at BrooklynResidency, Internal Medicine, 1972 - 1975
State University of New York Downstate Medical Center College of MedicineClass of 1972

Certifications & Licensure

NY State Medical License 1974 - Present
AL State Medical License 1984 - 2024
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Medical Oncology

Clinical Trials

Chemotherapy With or Without Bevacizumab in Treating Patients With Stage IB, Stage II, or Stage IIIA Non-small Cell Lung Cancer That Was Removed By Surgery Start of enrollment: 2007 Jun 01
Active, not recruiting
Phase 3
S0500 Treatment Decision Making Based on Blood Levels of Tumor Cells for Metastatic Breast Cancer Treated With Chemo Start of enrollment: 2006 Oct 01
Completed
Phase 3
S0809: Capecitabine, Gemcitabine, and RT in Patients w/Cholangiocarcinoma of the Gallbladder or Bile Duct Start of enrollment: 2008 Dec 01
Completed
Phase 2
S0802 - Topotecan With or Without Aflibercept in Treating Patients With Extensive-Stage Small Cell Lung Cancer Start of enrollment: 2009 May 01
Completed
Phase 2
S0702: Osteonecrosis of the Jaw in Patients With Cancer Receiving Zoledronic Acid for Bone Metastases Start of enrollment: 2008 Dec 01
Completed
S0819: Carboplatin and Paclitaxel With or Without Bevacizumab and/or Cetuximab in Treating Patients With Stage IV or Recurrent Non-Small Cell Lung Cancer Start of enrollment: 2009 Jul 15
Terminated
Phase 3
Gemcitabine Hydrochloride or Pemetrexed Disodium and Carboplatin With or Without Celecoxib in Treating Patients With Advanced Non-Small Cell Lung Cancer Start of enrollment: 2010 Feb 01
Terminated
Phase 3
Bevacizumab or Pemetrexed Disodium Alone or In Combination After Induction Therapy in Treating Patients With Advanced Non-Squamous Non-Small Cell Lung Cancer Start of enrollment: 2010 Oct 25
Completed
Phase 3
Chemotherapy With or Without Trastuzumab After Surgery in Treating Women With Invasive Breast Cancer Start of enrollment: 2011 Jan 06
Active, not recruiting
Phase 3
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Publications & Presentations

PubMed

11 citations
Paclitaxel/Carboplatin/Etoposide Versus Paclitaxel/Topotecan for Extensive-Stage Small Cell Lung Cancer: A Minnie Pearl Cancer Research Network Randomized, Prospective...
F. Anthony Greco, D. S. Thompson, Lisa H. Morrissey, Joan B. Erland, Howard A. Burris, David R. Spigel, Geetha Joseph, Steven W. Corso, Ellen Spremulli, John D. Hainsw...> ;The Oncologist. 2005 Oct 1
Paclitaxel/carboplatin/etoposide versus paclitaxel/topotecan for extensive stage small cell lung cancer: A Minnie Pearl Cancer Research Network randomized prospective ...
Thompson DS, Hainsworth JD, Morrissey LH, Erland JB, Burris HA, Joseph G, Corso SW, Spremulli E, Greco FA> ;J. Clin. Oncol.. 2004-07-15
7 citations
Clinical, pharmacologic, and immunologic effects of 2'-deoxycoformycin.
Frank J. Cummings, Gerald W. Crabtree, Michael C. Wiemann, Ellen N. Spremulli, Robert E. Parks, Paul Calabresi> ;Clinical Pharmacology and Therapeutics. 1988 Nov 1
2 citations
Phase I trial of the combination of 6-methylmercaptopurine riboside and 5-fluorouracil.
Michael C. Wiemann, Gerald W. Crabtree, Alan B. Weitberg, Ellen N. Spremulli, Frank J. Cummings, Connie Murray, Paul Calabresi> ;Medical Oncology and Tumor Pharmacotherapy. 1988 Jan 1
Tissue Analysis of N-Methylformamide: Organ Distribution
George M. Matook, Ellen N. Spremulli, Bruce K. Birmingham, Paul Calabresi, William C. Griffiths> ;Journal of Analytical Toxicology. 1984 May 1
6 citations
Nude Mouse Model of the Melanosis Syndrome
Ellen N. Spremulli, Hendrik A. Bogaars, Daniel L. Dexter, George M. Matook, G A Jolly, Richard E. Kuhn, Frank J. Cummings, Paul Calabresi> ;Journal of the National Cancer Institute. 1983 Nov 1
20 citations
Characterization of Two Metastatic Subpopulations Originating from a Single Human Colon Carcinoma
Ellen N. Spremulli, Caron Scott, Debora E. Campbell, N. Peter Libbey, Dan Shochat, David V. Gold, Daniel L. Dexter> ;Cancer Research. 1983 Aug 1
13 citations
Response of a human colon adenocarcinoma (DLD-1) to x irradiation and mitomycin C in vivo
Ellen N. Spremulli, John T. Leith, Bliven Sf, Debora E. Campbell, Daniel L. Dexter, Arvin S. Glicksman, Paul Calabresi> ;International Journal of Radiation Oncology, Biology, Physics. 1983 Aug 1
14 citations
Selection of Metastatic Variants from Heterogeneous Tumor Cell Lines Using the Chicken Chorioallantoic Membrane and Nude Mouse
Daniel L. Dexter, E S Lee, D J DeFusco, N P Libbey, Ellen N. Spremulli, Paul Calabresi> ;Cancer Research. 1983 Apr 1
2 citations
A Therapeutic Monitoring Assay for N-Methylformamide in Human Serum and Urine
William C. Griffiths, George M. Matook, Daniel L. Dexter, Gerald W. Crabtree, Ellen N. Spremulli, Paul Calabresi, Israel Diamond> ;Journal of Analytical Toxicology. 1983 Mar 1
2 citations
Biochemical pharmacology and toxicology of formycin alone and in combination with 2'-deoxycoformycin (pentostatin).
Ellen N. Spremulli, Gerald W. Crabtree, D L Dexter, Chu Sh, Farineau Dm, L Y Ghoda, McGowan Dl, Diamond I, R E Parks, Paul Calabresi> ;Cancer Treatment Reports. 1983 Mar 1
9 citations
Hemodynamic effects of potentially useful antineoplastic agents.
Ellen N. Spremulli, Frank J. Cummings, Gerald W. Crabtree, Kenneth LaBresh, Matthew Jordan, Paul Calabresi> ;Journal of the National Cancer Institute. 1983 Mar 1
51 citations
Inhibition of the growth of human colon cancer xenografts by polar solvents.
Daniel L. Dexter, Ellen N. Spremulli, George M. Matook, Israel Diamond, Paul Calabresi> ;Cancer Research. 1982 Dec 1
2 citations
Clinical and pharmacological studies of methotrexate-minimal leucovorin rescue plus fluorouracil.
Michael C. Wiemann, Frank J. Cummings, Henry G. Kaplan, Ellen N. Spremulli, Charles H. Doolittle, Paul Calabresi> ;Cancer Research. 1982 Sep 1
7 citations
Biochemical pharmacology and toxicology of 8-azaadenosine alone and in combination with 2'-deoxycoformycin (pentostatin)
Ellen N. Spremulli, Gerald W. Crabtree, Daniel L. Dexter, Shih Hsi Chu, Diane M. Farineau, Lucy Y. Ghoda, D.Lynn McGowan, Israel Diamond, Robert E. Parks, Paul Calabresi> ;Biochemical Pharmacology. 1982 Jul 15
2′-Deoxycoformycin-Induced Hemolysis in the Mouse
Ellen N. Spremulli, Gerald W. Crabtree, Daniel L. Dexter, Israel Diamond, Paul Calabresi> ;Journal of the National Cancer Institute. 1982 Jun 1
13 citations
Effect of low-dose heparin on the platelet count.
Alan B. Weitberg, Ellen N. Spremulli, Frank J. Cummings> ;Southern Medical Journal. 1982 Feb 1
132 citations
Heterogeneity of cancer cells from a single human colon carcinoma.
Daniel L. Dexter, Ellen N. Spremulli, Zuzana Fligiel, James A. Barbosa, Renee Vogel, Abby VanVoorhees, Paul Calabresi> ;The American Journal of Medicine. 1981 Dec 1
99 citations
Clinical studies on the radioimmunodetection of tumors containing alpha-fetoprotein.
David M. Goldenberg, E. Edmund, Frank H. DeLand, Ellen Spremulli, M. Owens Nelson, Jon P. Gockerman, F. James Primus, Robert L. Corgan, Elliot Alpert> ;Cancer. 1980 May 15
Phase II study of VM-26 in adult malignancies.
Spremulli E, Schulz JJ, Speckhart VJ, Wampler GL> ;Cancer Treat Rep. 1980-01-01
Human tumor cell heterogeneity and metastasis.
Spremulli, E. N., Dexter, D. L.> ;J Clin Oncol. 1983 Aug
Polar solvents: a novel class of antineoplastic agents.
Spremulli, E. N., Dexter, D. L.> ;J Clin Oncol. 1984 Mar
Randomized comparison of tamoxifen versus diethylstilbestrol in estrogen receptor-positive or -unknown metastatic breast cancer: a Southeastern Cancer Study Group trial.
Gockerman, J. P., Spremulli, E. N., Raney, M., Logan, T.> ;Cancer Treat Rep. 1986 Oct
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