IainPFraserMD

PubMed

• 2 citations
  Arachidonic acid inhibition of the NLRP3 inflammasome is a mechanism to explain the anti-inflammatory effects of fasting.
  Milton Pereira, Jonathan Liang, Joy Edwards-Hicks, Allison M Meadows, Christine Hinz, Sonia Liggi, Matthias Hepprich, Jonathan M Mudry, Kim Han, Julian L Griffin, Iain...> ;Cell Reports. 2024 Feb 27
• 21 citations
  Posoleucel, an Allogeneic, Off-the-Shelf Multivirus-Specific T-Cell Therapy, for the Treatment of Refractory Viral Infections in the Post-HCT Setting.
  Thomas Pfeiffer, Ifigeneia Tzannou, Mengfen Wu, Carlos Ramos, Ghadir Sasa, Caridad Martinez, Premal Lulla, Robert A Krance, Lauren Scherer, Daniel Ruderfer, Swati Naik...> ;Clinical Cancer Research. 2023 Jan 17
• 3 citations
  Evaluation of Pharmacokinetic Drug Interactions of the Direct-Acting Antiviral Agents Elbasvir and Grazoprevir with Pitavastatin, Rosuvastatin, Pravastatin, and Atorva...
  Luzelena Caro, Thomayant Prueksaritanont, Christine Fandozzi, Hwa-Ping Feng, Zifang Guo, Dennis Wolford, Deborah Panebianco, Iain P. Fraser, Vanessa Levine, Dennis Swe...> ;Clinical Drug Investigation. 2021 Feb 1
• Fine-Needle Aspiration for the Evaluation of Hepatic Pharmacokinetics of Vaniprevir: A Randomized Trial in Patients With Hepatitis C Virus Infection.
  W. Gao, Andrea L. Webber, Jill Maxwell, Melanie Anderson, Luzelena Caro, Chris Chung, André M. M. Miltenburg, Serghei Popa, Kristien Van Dyck, Larissa Wenning, Eric Ma...> ;Clinical Pharmacology and Therapeutics. 2020 Jun 1
• 3 citations
  Assessment of drug interaction potential between the HCV direct-acting antiviral agents elbasvir/grazoprevir and the HIV integrase inhibitors raltegravir and dolutegra...
  Hwa-Ping Feng, Zifang Guo, Lisa L. Ross, Iain P. Fraser, Deborah Panebianco, Patricia Jumes, Christine Fandozzi, Luzelena Caro, Jennifer Talaty, Joanne Ma, Eric Mangin...> ;The Journal of Antimicrobial Chemotherapy. 2019 Mar 1
• 9 citations
  Pharmacokinetic Interactions between the Hepatitis C Virus Inhibitors Elbasvir and Grazoprevir and HIV Protease Inhibitors Ritonavir, Atazanavir, Lopinavir, and Daruna...
  Hwa-Ping Feng, Luzelena Caro, Christine Fandozzi, Xiaoyan Chu, Zifang Guo, Jennifer Talaty, Deborah Panebianco, Katherine Dunnington, Lihong Du, William D. Hanley, Iai...> ;Antimicrobial Agents and Chemotherapy. 2019 Mar 27
• 9 citations
  A randomized clinical trial to evaluate the single‐dose pharmacokinetics, pharmacodynamics, and safety of sitagliptin in pediatric patients with type 2 diabetes
  Iain P. Fraser, Naomi D. Neufeld, Larry A. Fox, Mark S. Kipnes, Tracie L. Miller, Philip Zeitler, Henry Rodriguez, Jocelyn Gilmartin, Susan J. Lee, Jaclyn K. Patterson...> ;Pediatric Diabetes. 2019 Feb 1
• 19 citations
  Monoacylglycerol Lipase Inhibition in Human and Rodent Systems Supports Clinical Evaluation of Endocannabinoid Modulators.
  Jason R. Clapper, Cassandra L. Henry, Micah J. Niphakis, Anna M. Knize, Aundrea R. Coppola, Gabriel M. Simon, Nhi Ngo, Rachel A. Herbst, Dylan M. Herbst, Alex Reed, Ju...> ;The Journal of Pharmacology and Experimental Therapeutics. 2018 Dec 1
• 4 citations
  No Pharmacokinetic Interactions Between Elbasvir or Grazoprevir and Buprenorphine/Naloxone in Healthy Participants and Participants Receiving Stable Opioid Agonist The...
  Hwa-Ping Feng, Zifang Guo, Luzelena Caro, William L. Marshall, Fang Liu, Deborah Panebianco, Pavan Vaddady, April M. Barbour, Christina Reitmann, Patricia Jumes, Jocel...> ;Clinical and Translational Science. 2018 Jul 24
• 6 citations
  No Pharmacokinetic Interactions Between Elbasvir or Grazoprevir and Methadone in Participants Receiving Maintenance Opioid Agonist Therapy.
  Hwa-Ping Feng, Zifang Guo, Luzelena Caro, William L. Marshall, Fang Liu, Deborah Panebianco, Pavan Vaddady, Christina Reitmann, Patricia Jumes, Dennis Wolford, Iain Fr...> ;Clinical and Translational Science. 2018 Nov 1
• 3 citations
  Antiviral Activity, Safety, and Tolerability of Multiple Ascending Doses of Elbasvir or Grazoprevir in Participants Infected With Hepatitis C Virus Genotype-1 or -3.
  Wendy W. Yeh, Iain P. Fraser, Patricia Jumes, Amelia S. Petry, Inge De Lepeleire, Martine Robberechts, Christina Reitmann, Kristien Van Dyck, Xiaobi Huang, Zifang Guo,...> ;Clinical Therapeutics. 2018 Apr 25
• 10 citations
  Effect of Hepatic Impairment on the Pharmacokinetics of Grazoprevir, a Hepatitis C Virus Protease Inhibitor.
  Luzelena Caro, Larissa Wenning, Zifang Guo, Iain P. Fraser, Christine Fandozzi, Jennifer Talaty, Deborah Panebianco, Maureen Ho, Naoto Uemura, Christina Reitmann, Pete...> ;Antimicrobial Agents and Chemotherapy. 2017 Nov 22
• 10 citations
  Efavirenz modulation of sleep spindles and sleep spectral profile.
  Arthur A. Simen, Junshui Ma, Vladimir Svetnik, David Mayleben, James P Maynard, Adam Roth, Lori A. Mixson, Robin Mogg, David M. Shera, Laura George, T. Chris Mast, Cha...> ;Journal of Sleep Research. 2015 Feb 1
• 129 citations
  Pitavastatin is a more sensitive and selective organic anion-transporting polypeptide 1B clinical probe than rosuvastatin
  Thomayant Prueksaritanont, Xiaoyan Chu, Raymond Evers, Stephanie O. Klopfer, Luzelena Caro, Prajakti A. Kothare, Cynthia Dempsey, Scott Rasmussen, Robert Houle, Grace ...> ;British Journal of Clinical Pharmacology. 2014 Sep 1
• 13 citations
  Pharmacokinetics and tolerability of rizatriptan in pediatric migraineurs in a randomized study.
  Iain P. Fraser, Lingling Han, Tae H. Han, Chi-Chung Li, David Hreniuk, S. Aubrey Stoch, John A. Wagner, Steven L. Linder, Paul Winner> ;Headache. 2012 Apr 1
• 30 citations
  Effect of Different Durations and Formulations of Diltiazem on the Single-Dose Pharmacokinetics of Midazolam: How Long Do We Go?
  Evan J. Friedman, Iain P. Fraser, Ying-Hong Wang, Arthur J. Bergman, Chi-Chung Li, Patrick Larson, Chodakewitz Jeffrey A, John A. Wagner, S. Aubrey Stoch> ;Journal of Clinical Pharmacology. 2011 Nov 1
• 9 citations
  Suppurative lymphadenitis
  Iain P. Fraser> ;Current Infectious Disease Reports. 2009 Sep 1
• 74 citations
  Anti-inflammatory function of an in situ cross-linkable conjugate hydrogel of hyaluronic acid and dexamethasone.
  Taichi Ito, Iain P. Fraser, Yoon Yeo, Christopher B. Highley, Evangelia Bellas, Daniel S. Kohane> ;Biomaterials. 2007 Apr 1
• 15 citations
  Case records of the Massachusetts General Hospital. Case 32-2006. A 3-year-old girl with fever after a visit to Africa.
  Iain P. Fraser, Christine M. Cserti, Walter H. Dzik> ;The New England Journal of Medicine. 2006 Oct 19
• 227 citations
  Netrin-1 inhibits leukocyte migration in vitro and in vivo.
  Ngoc P. Ly, Katsumi Komatsuzaki, Iain P. Fraser, Anita A. Tseng, Kathryn J. Moore, T. Bernard Kinane> ;Proceedings of the National Academy of Sciences of the United States of America. 2005 Oct 11
• 106 citations
  Human peptidoglycan recognition protein S is an effector of neutrophil-mediated innate immunity
  Ju Hyun Cho, Iain P. Fraser, Koichi Fukase, Shoichi Kusumoto, Yukari Fujimoto, Gregory L. Stahl, R. Alan B. Ezekowitz> ;Blood. 2005 Oct 1
• 10 citations
  The mannose-binding lectin: an infection susceptibility gene.
  R. Alan B. Ezekowitz, Lei Shi, Iain P. Fraser, Kazue Takahashi> ;Advances in Experimental Medicine and Biology. 2005 Jan 1
• 9 citations
  TLR-independent pattern recognition receptors and anti-inflammatory mechanisms.
  Iain P. Fraser, Lynda M. Stuart, R. Alan B. Ezekowitz> ;Journal of Endotoxin Research. 2004 Jan 1
• 37 citations
  Pneumocystis carinii enhancessoluble mannose receptor production by macrophages
  Iain P. Fraser, Kazue Takahashi, Henry Koziel, Babak Fardin, Allen G. Harmsen, R. Alan B. Ezekowitz> ;Microbes and Infection. 2000 Sep 1
• 152 citations
  The serum mannose-binding protein and the macrophage mannose receptor are pattern recognition molecules that link innate and adaptive immunity.
  Iain P. Fraser, Henry Koziel, Ezekowitz Ra> ;Seminars in Immunology. 1998 Oct 1
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