IsabelleN.KingMD

Pediatrics • San Francisco, CA

Pediatric Critical Care Medicine, Hospice & Palliative Medicine

Assistant Professor, Pediatrics, UCSF School of Medicine

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Office
505 Parnassus Ave
San Francisco, CA 94143
Phone+1 415-476-5001

Fax+1 415-476-4009
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Education & Training

University of Texas Southwestern Medical CenterFellowship, Pediatric Critical Care Medicine, 2000 - 2005
Yale-New Haven Medical CenterResidency, Pediatrics, 1997 - 2000
Medical College of WisconsinClass of 1997

Certifications & Licensure

CA State Medical License 2005 - 2025
TX State Medical License 2004 - 2007
American Board of Pediatrics Pediatrics
American Board of Pediatrics Hospice and Palliative Medicine
American Board of Pediatrics Pediatric Critical Care Medicine

Awards, Honors, & Recognition

Super Doctor SuperDoctors.com

Publications & Presentations

PubMed

17 citations
The E3 ubiquitin ligase Nedd4/Nedd4L is directly regulated by microRNA 1.
Jun-yi Zhu, Amy Heidersbach, Irfan S. Kathiriya, Bayardo I. Garay, Kathryn N. Ivey, Deepak Srivastava, Zhe Han, Isabelle N. King> ;Development. 2017 Mar 1
62 citations
The RNA-binding protein TDP-43 selectively disrupts microRNA-1/206 incorporation into the RNA-induced silencing complex.
Isabelle N. King, Valeria Yartseva, Donaldo Salas, Abhishek Kumar, Amy Heidersbach, D. Michael Ando, Nancy R. Stallings, Jeffrey L. Elliott, Deepak Srivastava, Kathryn...> ;The Journal of Biological Chemistry. 2014 May 16
209 citations
Notch post-translationally regulates β-catenin protein in stem and progenitor cells
Chulan Kwon, Paul Cheng, Isabelle N. King, Peter Andersen, Lincoln T. Shenje, Vishal Nigam, Deepak Srivastava> ;Nature Cell Biology. 2011 Oct 1
59 citations
Tinman/Nkx2-5 acts via miR-1 and upstream of Cdc42 to regulate heart function across species
Li Qian, Joshua D. Wythe, Jiandong Liu, Jérôme Cartry, Georg Vogler, Bhagyalaxmi Mohapatra, Robyn Otway, Yu Huang, Isabelle N. King, Marjorie Maillet, Yi Zheng, Timoth...> ;The Journal of Cell Biology. 2011 Jun 27
26 citations
A Genome-Wide Screen Reveals a Role for microRNA-1 in Modulating Cardiac Cell Polarity
Isabelle N. King, Li Qian, Jianping Liang, Yu Huang, Joseph T. Shieh, Chulan Kwon, Deepak Srivastava> ;Developmental Cell. 2011 Apr 19
14 citations
A Rare Human Sequence Variant Reveals Myocardin Autoinhibition
Joshua F. Ransom, Isabelle N. King, Vidu Garg, Deepak Srivastava> ;The Journal of Biological Chemistry. 2008 Dec 19
16 citations
Vertebrate heart growth is regulated by functional antagonism between Gridlock and Gata5
Haibo Jia, Isabelle N. King, Sameer S. Chopra, Haiyan Wan, Terri T. Ni, Charlie Jiang, Xiaoqun Guan, Samuel A. Wells, Deepak Srivastava, Tao P. Zhong> ;Proceedings of the National Academy of Sciences of the United States of America. 2007 Aug 28
28 citations
Hrt and Hes negatively regulate Notch signaling through interactions with RBP-Jκ
Isabelle N. King, Irfan S. Kathiriya, Masao Murakami, Masayo Nakagawa, Kelly A. Gardner, Deepak Srivastava, Osamu Nakagawa> ;Biochemical and Biophysical Research Communications. 2006 Jun 23
1029 citations
Mutations in NOTCH1 cause aortic valve disease
Vidu Garg, Alecia N. Muth, Joshua F. Ransom, Marie K. Schluterman, Robert Barnes, Isabelle N. King, Paul Grossfeld, Deepak Srivastava> ;Nature. 2005 Sep 8
58 citations
Hairy-related Transcription Factors Inhibit GATA-dependent Cardiac Gene Expression through a Signal-responsive Mechanism
Irfan S. Kathiriya, Isabelle N. King, Masao Murakami, Masayo Nakagawa, John Astle, Kelly A. Gardner, Robert D. Gerard, Eric N. Olson, Deepak Srivastava, Osamu Nakagawa> ;The Journal of Biological Chemistry. 2004 Dec 24
868 citations
GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5
Vidu Garg, Irfan S. Kathiriya, Robert Barnes, Marie K. Schluterman, Isabelle N. King, Cheryl A. Butler, Caryn R. Rothrock, Reenu S. Eapen, Kayoko Hirayama-Yamada, Kuni...> ;Nature. 2003 Jul 24
Plastid-localized acetyl-CoA carboxylase of bread wheat is encoded by a single gene on each of the three ancestral chromosome sets.
Gornicki P, Faris J, King I, Podkowinski J, Gill B, Haselkorn R> ;Proc. Natl. Acad. Sci. U.S.A.. 1997-12-09
36 citations
Thyroid hormone receptor-induced bending of specific DNA sequences is modified by an accessory factor.
Isabelle N. King, T de Soyza, Daniel F. Catanzaro, Thomas N. Lavin> ;The Journal of Biological Chemistry. 1993 Jan 5
195 citations
The angiotensin AT2 receptor stimulates protein tyrosine phosphatase activity and mediates inhibition of particulate guanylate cyclase.
Serge P. Bottari, Isabelle N. King, Serge Reichlin, Ilse Dahlstroem, Nicholas B. Lydon, Marc de Gasparo> ;Biochemical and Biophysical Research Communications. 1992 Feb 28
102 citations
Angiotensin II AT2 receptors do not interact with guanine nucleotide binding proteins.
Serge P. Bottari, Verdon Taylor, Isabelle N. King, Yvonne Bogdal, Steven Whitebread, Marc de Gasparo> ;European Journal of Pharmacology. 1991 Jun 19
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Grant Support

Basil O'Connor AwardMarch of Dimes2011–2012
Hairy-Related Factors In Cardiac Development And DiseaseNational Heart, Lung, And Blood Institute2005–2009

Hospital Affiliations

Kaiser Permanente Oakland Medical CenterOakland, California
MarinHealth Medical CenterGreenbrae, California