SamuelHawgoodMD

Pediatrics • San Francisco, CA

Professor, Dean's Office, University of California, San Francisco, School of Medicine

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Office
533 Parnassus Ave
San Francisco, CA 94143
Phone+1 415-476-9181

Fax+1 415-476-4009
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Education & Training

The University of Queensland Medical SchoolClass of 1975

Certifications & Licensure

CA State Medical License 1986 - 2025

Awards, Honors, & Recognition

Elected Member Institute of Medicine, 2009
Elected Member The American Society for Clinical Investigation, 1995

Publications & Presentations

PubMed

26 citations
A new data effort to inform career choices in biomedicine.
Rebecca M. Blank, Ronald J. Daniels, Gary Gilliland, Amy Gutmann, Samuel Hawgood, Freeman A. Hrabowski, Martha E. Pollack, Vincent Price, L. Rafael Reif, Mark S. Schli...> ;Science. 2017 Dec 15
27 citations
Innate immunity of surfactant proteins A and D in urinary tract infection with uropathogenic Escherichia coli.
Fengqi Hu, Guohua Ding, Zhiyong Zhang, Louis A. Gatto, Samuel Hawgood, Francis R Poulain, Robert N. Cooney, Guirong Wang> ;Innate Immunity. 2016 Jan 1
17 citations
Protective Role of Surfactant Protein D in Ocular Staphylococcus aureus Infection.
Zhiyong Zhang, Osama Abdel-Razek, Samuel Hawgood, Guirong Wang> ;Plos One. 2015 Sep 23
74 citations
Precision medicine: Beyond the inflection point.
Samuel Hawgood, India G. Hook-Barnard, Theresa C. O’Brien, Keith R. Yamamoto> ;Science Translational Medicine. 2015 Aug 12
7 citations
Commentary: Team science.
Theresa C. O’Brien, Keith R. Yamamoto, Samuel Hawgood> ;Academic Medicine. 2013 Feb 1
63 citations
Mice Deficient in Surfactant Protein A (SP-A) and SP-D or in TLR2 Manifest Delayed Parturition and Decreased Expression of Inflammatory and Contractile Genes
Alina P. Montalbano, Samuel Hawgood, Carole R. Mendelson> ;Endocrinology. 2013 Jan 1
14 citations
Surfactant Protein D Deficiency in Mice Is Associated with Hyperphagia, Altered Fat Deposition, Insulin Resistance, and Increased Basal Endotoxemia
Jacob V Stidsen, Reza Khorooshi, Martin K U Rahbek, Katrine Lindequist Kirketerp-Møller, Pernille B. Lærkegaard Hansen, Peter Bie, Karin Kejling, Susanne Mandrup, Samu...> ;Plos One. 2012 Apr 11
111 citations
Congenital diaphragmatic hernia: endothelin-1, pulmonary hypertension, and disease severity.
Roberta L. Keller, Theresa A. Tacy, Karen D. Hendricks-Muñoz, Jie Xu, Anita J. Moon-Grady, John Neuhaus, Phillip Moore, Kerilyn K. Nobuhara, Samuel Hawgood, Jeffrey R....> ;American Journal of Respiratory and Critical Care Medicine. 2010 Aug 15
50 citations
Susceptibility of mice genetically deficient in SP-A or SP-D gene to invasive pulmonary aspergillosis
Taruna Madan, Kenneth B.M. Reid, Howard Clark, Mamta Singh, Annapurna Nayak, P. Usha Sarma, Samuel Hawgood, Uday Kishore> ;Molecular Immunology. 2010 Jun 1
56 citations
Clearance of Pseudomonas aeruginosa from a healthy ocular surface involves surfactant protein D and is compromised by bacterial elastase in a murine null-infection model.
James J. Mun, Connie Tam, David Kowbel, Samuel Hawgood, Mitchell J. Barnett, David J. Evans, Suzanne M. J. Fleiszig> ;Infection and Immunity. 2009 Jun 1
6 citations
Simultaneous absence of surfactant proteins A and D increases lung inflammation and injury after allogeneic HSCT in mice
Kendra Gram, Shuxia Yang, Marie E. Steiner, Arif Somani, Samuel Hawgood, Bruce R. Blazar, Angela Panoskaltsis-Mortari, Imad Y. Haddad> ;American Journal of Physiology. Lung Cellular and Molecular Physiology. 2009 Feb 1
20 citations
A Recombinant Fragment of Human Surfactant Protein D Lacking the Short Collagen-Like Stalk Fails to Correct Morphological Alterations in Lungs of SP-D Deficient Mice
Lars Knudsen, Katharina Wucherpfennig, Rose-Marie Mackay, Paul A. Townsend, Christian Mühlfeld, Joachim Richter, Samuel Hawgood, Kenneth B.M. Reid, Howard Clark, Matth...> ;Anatomical Record. 2009 Feb 1
22 citations
Expression of surfactant protein D in human corneal epithelial cells is upregulated by Pseudomonas aeruginosa
Minjian Ni, Connie Tam, Amrisha Verma, Reuben Ramphal, Samuel Hawgood, David J. Evans, Suzanne M. J. Fleiszig> ;FEMS Immunology and Medical Microbiology. 2008 Nov 1
27 citations
Genetic analysis of congenital cystic adenomatoid malformation reveals a novel pulmonary gene: fatty acid binding protein-7 (brain type).
Amy J. Wagner, Amber Stumbaugh, Zachary Tigue, Jess Edmondson, Agnes C. Paquet, Diana L. Farmer, Samuel Hawgood> ;Pediatric Research. 2008 Jul 1
29 citations
Laser microdissection allows detection of abnormal gene expression in cystic adenomatoid malformation of the lung.
Tim Jancelewicz, Kerilyn K. Nobuhara, Samuel Hawgood> ;Journal of Pediatric Surgery. 2008 Jun 1
61 citations
Truncated recombinant human SP-D attenuates emphysema and type II cell changes in SP-D deficient mice.
Lars Knudsen, Matthias Ochs, Rose-Marie Mackay, Paul A. Townsend, Roona Deb, Christian Mühlfeld, Joachim Richter, Fabian Gilbert, Samuel Hawgood, Kenneth B.M. Reid, Ho...> ;Respiratory Research. 2007 Oct 3
138 citations
N-Linked Glycosylation Attenuates H3N2 Influenza Viruses
David J. Vigerust, Kimberly B. Ulett, Kelli L. Boyd, Jens Madsen, Samuel Hawgood, Jonathan A. McCullers> ;Journal of Virology. 2007 Aug 15
31 citations
Integrin β6 Mediates Phospholipid and Collectin Homeostasis by Activation of Latent TGF-β1
Laura L. Koth, Byron Alex, Samuel Hawgood, Michael A. Nead, Dean Sheppard, David J. Erle, David G. Morris> ;American Journal of Respiratory Cell and Molecular Biology. 2007 Jul 19
7 citations
Helicobacter infection in the surfactant protein D-deficient mouse
Wafa Khamri, M. Worku, Amy E. Anderson, Marjorie M. Walker, Samuel Hawgood, Kenneth B.M. Reid, Howard Clark, Mark Thursz> ;Helicobacter. 2007 Apr 1
62 citations
Role of surfactant protein-A (SP-A) in lung injury in response to acute ozone exposure of SP-A deficient mice.
Rizwanul Haque, Todd M. Umstead, Padmavathi Ponnuru, Xiaoxuan Guo, Samuel Hawgood, David S. Phelps, Joanna Floros> ;Toxicology and Applied Pharmacology. 2007 Apr 1
35 citations
Surfactant protein D of the innate immune defence is inversely associated with human obesity and SP-D deficiency infers increased body weight in mice.
Grith Lykke Sørensen, Jacob v. B. Hjelmborg, Rikke Leth-Larsen, Vivi Schmidt, Mogens Fenger, Francis R Poulain, Samuel Hawgood, Thorkild I. A. Sørensen, Kirsten Ohm Ky...> ;Scandinavian Journal of Immunology. 2006 Dec 1
35 citations
Abnormal vascular tone in infants and children with lung hypoplasia: Findings from cardiac catheterization and the response to chronic therapy.
Roberta L. Keller, Phillip Moore, David F. Teitel, Samuel Hawgood, John McQuitty, Jeffrey R. Fineman> ;Pediatric Critical Care Medicine. 2006 Nov 1
91 citations
Deletion of the Transmembrane Transporter ABCG1 Results in Progressive Pulmonary Lipidosis
Ángel Baldán, Paul T. Tarr, Charisse Vales, Joy S. Frank, Thomas K. Shimotake, Samuel Hawgood, Peter A. Edwards> ;The Journal of Biological Chemistry. 2006 Sep 29
51 citations
Surfactant protein D is proatherogenic in mice.
Grith Lykke Sørensen, Jens Madsen, Karin Kejling, Ida Tornøe, Ole John Nielsen, Paul A. Townsend, Francis R Poulain, Claus Henrik Nielsen, Kenneth B.M. Reid, Samuel Ha...> ;American Journal of Physiology. Heart and Circulatory Physiology. 2006 Jun 1
69 citations
IL-4 and IL-13 form a negative feedback circuit with surfactant protein-D in the allergic airway response.
Angela Franciska Haczku, Yang Cao, Geza Vass, S. Kierstein, Puneeta Nath, Elena N. Atochina-Vasserman, Seth T. Scanlon, Lily Li, Don E. Griswold, K. Fan Chung, Francis...> ;Journal of Immunology. 2006 Mar 15
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Press Mentions

Surfactant Protein A Reduces TLR4 and Inflammatory Cytokine mRNA Levels in Neonatal Mouse IleumJanuary 28th, 2021

Grant Support

Administration CoreNational Heart, Lung, And Blood Institute2011–2012
Structure And Function Of Surfactant ApoproteinsNational Heart, Lung, And Blood Institute1995–2012
Development And Control Of Pulmonary Alveolar StabilityNational Heart, Lung, And Blood Institute1994–2012
Nichd Institutional Training For PediatriciansEunice Kennedy Shriver National Institute Of Child Health &Human Development2003–2010
Graduate Research Training In Perinatal BiologyEunice Kennedy Shriver National Institute Of Child Health &Human Development2007–2008
Faseb Summer Research Conference, Lung Surfactant: Molecular And Cell BiologyNational Heart, Lung, And Blood Institute2006
Core A- AdministrativeNational Heart, Lung, And Blood Institute2004
Magnetic Resonance Imaging And Velocity-Encoded MRI Of Pulmonary ArteriesNational Center For Research Resources2004
Collectin Deficiency In The MouseNational Heart, Lung, And Blood Institute2001–2004
Collectin DeficiencyNational Heart, Lung, And Blood Institute1997–2000

Hospital Affiliations

Zuckerberg San Francisco General Hospital and Trauma CenterSan Francisco, California