James Brugarolas MD PhD
Genitourinary Oncology, Hematologic Oncology
Director, Kidney Cancer Program; Sherry Wigley Crow Endowed Chair in Cancer Research; Professor of Internal Medicine/ Hematology-Oncology, Cancer Biology, Genetics, Development and Disease at UT Southwestern Medical Center
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5323 Harry Hines BoulevardDallas, TX 75390
Phone+1 214-645-4673
Fax+1 214-645-2542
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Summary
Clinical Expertise
- Kidney Neoplasms, Renal cell carcinoma, Urologic oncology, Hematologic oncology
Education & Training
Mass General Brigham/Brigham and Women's Hospital/Massachusetts General Hospital/Dana-Farber Cancer InstituteFellowship, Hematology and Medical Oncology, 2001 - 2003
Duke University HospitalResidency, Internal Medicine, 1998 - 2001
Massachusetts Institute of TechnologyPhD, Biology, 1993 - 1998
Universidad de Navarra Faculty of MedicineClass of 1993
Certifications & Licensure
TX State Medical License 2006 - 2026
MA State Medical License 2002 - 2007
NC State Medical License 1998 - 2004
American Board of Internal Medicine Medical Oncology
Awards, Honors, & Recognition
- Elected member Association of American Physicians, 2025
- Principal Investigator, Kidney Cancer Specialized Program of Research Excellence (SPORE) National Cancer Institute
- Elected to the American Society for Clinical Investigation 2013
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Publications & Presentations
PubMed
- Glycosaminoglycan-driven lipoprotein uptake protects tumours from ferroptosis.Dylan Calhoon, Lingjie Sang, Fubo Ji, Divya Bezwada, Sheng-Chieh Hsu
Nature. 2025-06-11 - SWI/SNF ATPase silenced HLF potentiates lung metastasis in solid cancers.Jin Zhou, Austin Hepperla, Jeremy M Simon, Kangsan Kim, Qing Hu
Nature Communications. 2025-06-05 - Iterative refinement and goal articulation to optimize large language models for clinical information extraction.David Hein, Alana Christie, Michael Holcomb, Bingqing Xie, A J Jain
NPJ Digital Medicine. 2025-05-23
Press Mentions
HMN 2025: How Cancer Cells Exploit Various Pathway to Assemble Antioxidant Lipids and Evade Cell DemiseJune 14th, 2025- Children’s Research Institute Scientists Uncover Unique Pathway Tumors Use to Acquire Antioxidant LipidsJune 11th, 2025
- Study Uncovers How Biomolecular Condensates Cause Some Kidney CancersJune 4th, 2025
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Grant Support
- University of Texas Southwestern Medical Center SPORE in Kidney CancerUT SOUTHWESTERN MEDICAL CENTER2016–2027
- Specialized Program of Research Excellence (SPORE)NIH/NCI2016–Present
Committees
- Chair, Scientific Advisory Board, National Kidney Cancer Academy 2020 - Present
- Chair, Congressionally Directed Medical Research Program – Kidney Cancer Research Program 2017 - 2018
Professional Memberships
- Member
- Member
- American Society for Clinical Investigation - ASCIMember
Other Languages
- Spanish
External Links
- Kidney Cancer Programhttp://www.utsouthwestern.edu/kidneycancer
- Brugarolas Labhttp://www.brugarolaslab.com
- Kidney Cancer SPOREhttps://trp.cancer.gov/spores/kidney.htm
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