JamesBrufauBrugarolasMDPhD
Oncology • Dallas, TXGenitourinary Oncology, Hematologic Oncology
Director, Kidney Cancer Program; Sherry Wigley Crow Endowed Chair in Cancer Research; Professor of Internal Medicine/ Hematology-Oncology, Cancer Biology, Genetics, Development and Disease at UT Southwestern Medical Center
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Office
5323 Harry Hines Boulevard
Dallas, TX 75390Phone+1 214-645-4673Fax+1 214-645-2542- Is this information wrong?
Summary
Clinical Expertise
- Kidney Neoplasms, Renal cell carcinoma, Urologic oncology, Hematologic oncology
Education & Training
Brigham and Women's Hospital/Massachusetts General Hospital/Dana-Farber Cancer InstituteFellowship, Hematology and Medical Oncology, 2001 - 2003
Duke University HospitalResidency, Internal Medicine, 1998 - 2001
Massachusetts Institute of TechnologyPhD, Biology, 1993 - 1998
Universidad de Navarra Faculty of MedicineClass of 1993
Certifications & Licensure
TX State Medical License 2006 - 2024
MA State Medical License 2002 - 2007
NC State Medical License 1998 - 2004- American Board of Internal Medicine Medical Oncology
Awards, Honors, & Recognition
- Principal Investigator, Kidney Cancer Specialized Program of Research Excellence (SPORE) National Cancer Institute
- Elected to the American Society for Clinical Investigation 2013
- Individual Investigator Research Award Cancer Prevention and Research Institute of Texas, 2010
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Publications & Presentations
PubMed
- Comparative genomics incorporating translocation renal cell carcinoma mouse model reveals molecular mechanisms of tumorigenesis.Gopinath Prakasam, Akhilesh Mishra, Alana Christie, Jeffrey Miyata, Deyssy Carrillo, Vanina T Tcheuyap, Hui Ye, Quyen N Do, Yunguan Wang, Oscar Reig Torras, Ramesh But...> ;The Journal of Clinical Investigation. 2024 Feb 22
- 1 citationsKinome-wide siRNA screen identifies a DCLK2-TBK1 oncogenic signaling axis in clear cell renal cell carcinoma.Hu, L., Zhang, Y., Guo, L., Zhong, H., Xie, L., Zhou, J., Liao, C., Yao, H., Fang, J., Liu, H., Zhang, C., Zhang, H., Zhu, X., Luo, M., von Kriegsheim, A., Li, B., Luo...> ;Molecular Cell. 2024 Feb 15
- 3 citationsRecent Advances in Renal Tumors with TSC/mTOR Pathway Abnormalities in Patients with Tuberous Sclerosis Complex and in the Sporadic Setting.Payal Kapur, James Brugarolas, Kiril Trpkov> ;Cancers. 2023 Aug 10
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Press Mentions
Clinical Trials for Kidney Cancer: What to KnowDecember 26th, 2022- Tackling HIF2 Drug Resistance with an RNA-Based Therapy: NewsroomOctober 3rd, 2022
- Clinical Trial Sets Stage for New Paradigm in Kidney Cancer TreatmentAugust 18th, 2022
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Grant Support
- Specialized Program of Research Excellence (SPORE)NIH/NCI2016–Present
Committees
- Chair, Scientific Advisory Board, National Kidney Cancer Academy 2020 - Present
- Chair, Congressionally Directed Medical Research Program – Kidney Cancer Research Program 2017 - 2018
Professional Memberships
- Member
- Member
- American Society for Clinical Investigation - ASCIMember
Other Languages
- Spanish
Hospital Affiliations
University of Texas Southwestern Medical CenterDallas, Texas
External Links
- Kidney Cancer Programhttp://www.utsouthwestern.edu/kidneycancer
- Brugarolas Labhttp://www.brugarolaslab.com
- Kidney Cancer SPOREhttps://trp.cancer.gov/spores/kidney.htm
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