James Brugarolas MD PhD
Genitourinary Oncology, Hematologic Oncology
Director, Kidney Cancer Program; Sherry Wigley Crow Endowed Chair in Cancer Research; Professor of Internal Medicine/ Hematology-Oncology, Cancer Biology, Genetics, Development and Disease at UT Southwestern Medical Center
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5323 Harry Hines BoulevardDallas, TX 75390
Phone+1 214-645-4673
Fax+1 214-645-2542
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Summary
Clinical Expertise
- Kidney Neoplasms, Renal cell carcinoma, Urologic oncology, Hematologic oncology
Education & Training
Mass General Brigham/Brigham and Women's Hospital/Massachusetts General Hospital/Dana-Farber Cancer InstituteFellowship, Hematology and Medical Oncology, 2001 - 2003
Duke University HospitalResidency, Internal Medicine, 1998 - 2001
Massachusetts Institute of TechnologyPhD, Biology, 1993 - 1998
Universidad de Navarra Faculty of MedicineClass of 1993
Certifications & Licensure
TX State Medical License 2006 - 2026
MA State Medical License 2002 - 2007
NC State Medical License 1998 - 2004
American Board of Internal Medicine Medical Oncology
Awards, Honors, & Recognition
- Principal Investigator, Kidney Cancer Specialized Program of Research Excellence (SPORE) National Cancer Institute
- Elected to the American Society for Clinical Investigation 2013
- Individual Investigator Research Award Cancer Prevention and Research Institute of Texas, 2010
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Publications & Presentations
PubMed
- RNA polymerase II partitioning is a shared feature of diverse oncofusion condensates.Heankel Lyons, Prashant Pradhan, Gopinath Prakasam, Shubham Vashishtha, Xiang Li
Cell. 2025-04-23 - An ultraconserved snoRNA-like element in long noncoding RNA CRNDE promotes ribosome biogenesis and cell proliferation.Jong-Sun Lee, Tu Dan, He Zhang, Yujing Cheng, Frederick Rehfeld
Molecular Cell. 2025-04-17 - Prompts to Table: Specification and Iterative Refinement for Clinical Information Extraction with Large Language Models.David Hein, Alana Christie, Michael Holcomb, Bingqing Xie, A J Jain
Medrxiv. 2025-04-01
Press Mentions
Clinical Trials for Kidney Cancer: What to KnowDecember 26th, 2022- Tackling HIF2 Drug Resistance with an RNA-Based Therapy: NewsroomOctober 3rd, 2022
- Clinical Trial Sets Stage for New Paradigm in Kidney Cancer TreatmentAugust 18th, 2022
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Grant Support
- University of Texas Southwestern Medical Center SPORE in Kidney CancerUT SOUTHWESTERN MEDICAL CENTER2016–2027
- Specialized Program of Research Excellence (SPORE)NIH/NCI2016–Present
Committees
- Chair, Scientific Advisory Board, National Kidney Cancer Academy 2020 - Present
- Chair, Congressionally Directed Medical Research Program – Kidney Cancer Research Program 2017 - 2018
Professional Memberships
- Member
- Member
- American Society for Clinical Investigation - ASCIMember
Other Languages
- Spanish
External Links
- Kidney Cancer Programhttp://www.utsouthwestern.edu/kidneycancer
- Brugarolas Labhttp://www.brugarolaslab.com
- Kidney Cancer SPOREhttps://trp.cancer.gov/spores/kidney.htm
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