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Office
55 Fruit St
Yaw 7
Boston, MA 02114Phone+1 617-724-4000Fax+1 617-278-6995- Is this information wrong?
Education & Training
Brigham and Women's Hospital/Massachusetts General Hospital/Dana-Farber Cancer InstituteFellowship, Hematology and Medical Oncology, 2002 - 2005- Brigham and Women's HospitalResidency, Internal Medicine, 2000 - 2002
Albert Einstein College of MedicineClass of 2000
Certifications & Licensure
MA State Medical License 2003 - 2022
Awards, Honors, & Recognition
- Elected Member The American Society for Clinical Investigation, 2011
Clinical Trials
- BKM120 in Cancers With PIK3CA Activating Mutations Start of enrollment: 2012 Jan 01
Publications & Presentations
PubMed
- 1 citationsExpressed Barcoding Enables High-Resolution Tracking of the Evolution of Drug Tolerance.Jennifer L Cotton, Javier Estrada Diez, Vivek Sagar, Julie Chen, Michelle Piquet, John Alford, Youngchul Song, Xiaoyan Li, Markus Riester, Matthew T DiMare, Katja Schu...> ;Cancer Research. 2023 Nov 1
- 16 citationsTherapy-induced APOBEC3A drives evolution of persistent cancer cells.Hideko Isozaki, Ramin Sakhtemani, Ammal Abbasi, Naveed Nikpour, Marcello Stanzione, Sunwoo Oh, Adam Langenbucher, Susanna Monroe, Wenjia Su, Heidie Frisco Cabanos, Far...> ;Nature. 2023 Aug 1
- 2 citationsIntegrated CRISPR screening and drug profiling identifies combination opportunities for EGFR, ALK, and BRAF/MEK inhibitors.Ralph Tiedt, Frederick J King, Christelle Stamm, Matthew J Niederst, Scott Delach, Sabine Zumstein-Mecker, Jodi Meltzer, Iain J Mulford, Emma Labrot, Barbara Schacher ...> ;Cell Reports. 2023 Apr 25
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Journal Articles
- Genetic Mechanisms of Target Antigen Loss in CAR19 Therapy of Acute Lymphoblastic LeukemiaJohn E Levine, Muna Qayed, Stephan A Grupp, Eneida R Nemecek, Stella M Davies, Michael R Verneris, Michael Boyer, Jeffrey A Engelman, Nature
- Genomic Correlates of Response to Immune Checkpoint Blockade in Microsatellite-Stable Solid TumorsJeffrey A Engelman, David A Barbie, Nicole G Chau, Glenn J Hanna, Natalie I Vokes, Sabina Signoretti, Pasi A Janne, Robert I Haddad, Lynette M Sholl, Rizwan Haq, Peter..., Nature
Press Mentions
JAMA Study Shows Pharma Companies Struggle to Meet Postapproval Study DeadlinesOctober 6th, 2022
Evaluating First-Line Ceritinib Therapy in ALK-Rearranged NSCLC PatientsSeptember 13th, 2017
Brain Microenvironment Makes HER2-Positive Breast Cancer Metastases Resistant to TreatmentMay 24th, 2017- Join now to see all
Grant Support
- Identification Of Resistance Mechanisms To Anaplastic Lymphoma Kinase InhibitorsNational Cancer Institute2012
- The Activation Of ERBB3 Signaling As A Resistance Mechanism To Targeted TherapiesNational Cancer Institute2009–2012
- Inhibition Of P13K And MEK Pathways In The Treatment Of Lung CancerNational Cancer Institute2009–2011
- Molecular Mechanisms Of PI3K Activation In Non-Small Cell Lung CancerNational Cancer Institute2006–2010
Professional Memberships
- Member
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