RushdiaZYusufMD

Oncology • Boston, MA

Instructor in Medicine, Massachusetts General Hospital

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Office
Grb 740, 55 Fruit Street
Mass General Hospital
Boston, MA 02114
Phone+1 617-726-2000

Fax+1 617-724-2662
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Education & Training

Brigham and Women's Hospital/Massachusetts General Hospital/Dana-Farber Cancer InstituteFellowship, Hematology and Medical Oncology, 2006 - 2010
Massachusetts General HospitalResidency, Internal Medicine, 2003 - 2006
Aga Khan Medical CollegeClass of 2000

Certifications & Licensure

MA State Medical License 2005 - 2025
American Board of Internal Medicine Medical Oncology

Publications & Presentations

PubMed

6 citations
The bone marrow niche regulates redox and energy balance in MLL::AF9 leukemia stem cells.
Ana C Viñado, Isabel A Calvo, Itziar Cenzano, Danel Olaverri, Miguel Cocera, Patxi San Martin-Uriz, Juan P Romero, Amaia Vilas-Zornoza, Laura Vera, Nuria Gomez-Cebrian...> ;Leukemia. 2022 Aug 1
60 citations
Aldehyde dehydrogenase 3a2 protects AML cells from oxidative death and the synthetic lethality of ferroptosis inducers.
Rushdia Z. Yusuf, Borja Saez, Azeem Sharda, Nick van Gastel, Vionnie W.C. Yu, Ninib Baryawno, Elizabeth W. Scadden, Sanket S. Acharya, Shrikanta Chattophadhyay, Cherri...> ;Blood. 2020 Sep 10
24 citations
Bortezomib-based immunosuppression after reduced-intensity conditioning hematopoietic stem cell transplantation: randomized phase II results.
John Koreth, Haesook T. Kim, Paulina B. Lange, Samuel J. Poryanda, Carol Reynolds, Sharmila Chamling Rai, Philippe Armand, Corey Cutler, Vincent T. Ho, Brett Glotzbeck...> ;Haematologica. 2018 Mar 1
48 citations
Epigenetic Memory Underlies Cell-Autonomous Heterogeneous Behavior of Hematopoietic Stem Cells.
Vionnie W C Yu, Rushdia Z Yusuf, Toshihiko Oki, Juwell Wu, Borja Saez, Xin Wang, Colleen Cook, Ninib Baryawno, Michael J Ziller, Eunjung Lee, Hongcang Gu, Alexander Me...> ;Cell. 2017 Feb 23
27 citations
Epigenetic Memory Underlies Cell-Autonomous Heterogeneous Behavior of Hematopoietic Stem Cells.
Vionnie W C Yu, Rushdia Z Yusuf, Toshihiko Oki, Juwell Wu, Borja Saez, Xin Wang, Colleen Cook, Ninib Baryawno, Michael J Ziller, Eunjung Lee, Hongcang Gu, Alexander Me...> ;Cell. 2016 Nov 17
107 citations
PHD3 Loss in Cancer Enables Metabolic Reliance on Fatty Acid Oxidation via Deactivation of ACC2
Natalie J. German, Haejin Yoon, Rushdia Z. Yusuf, J. Patrick Murphy, Lydia W.S. Finley, Gaëlle Laurent, Wilhelm Haas, F. Kyle Satterstrom, Jlenia Guarnerio, Elma Zagan...> ;Molecular Cell. 2016 Sep 15
21 citations
Niche-Based Screening in Multiple Myeloma Identifies a Kinesin-5 Inhibitor with Improved Selectivity over Hematopoietic Progenitors
Shrikanta Chattopadhyay, Alison L. Stewart, Siddhartha Mukherjee, Cherrie Huang, Kimberly A. Hartwell, Peter Miller, Radhika Subramanian, Leigh C. Carmody, Rushdia Z. ...> ;Cell Reports. 2015 Feb 10
38 citations
Inhibiting stromal cell heparan sulfate synthesis improves stem cell mobilization and enables engraftment without cytotoxic conditioning
Borja Saez, Francesca Ferraro, Rushdia Z. Yusuf, Colleen Cook, Vionnie W.C. Yu, Ana Pardo-Saganta, Stephen M. Sykes, Rahul Palchaudhuri, Amir Schajnovitz, Sutada Lotin...> ;Blood. 2014 Nov 6
59 citations
Purinergic P2Y14 receptor modulates stress-induced hematopoietic stem/progenitor cell senescence
Joonseok Cho, Rushdia Z. Yusuf, Sung-Ho Kook, Eyal C. Attar, Dongjun Lee, Bae-Hang Park, Tao Cheng, David T. Scadden, Byeong Chel Lee> ;The Journal of Clinical Investigation. 2014 Jul 1
742 citations
Direct measurement of local oxygen concentration in the bone marrow of live animals
Joel A. Spencer, Francesca Ferraro, Emmanuel Roussakis, Alyssa Klein, Juwell W. Wu, Judith Runnels, Walid Abbas Zaher, Luke J. Mortensen, Clemens Alt, Raphaël Turcotte...> ;Nature. 2014 Apr 10
19 citations
Fate through Fat: Lipid Metabolism Determines Stem Cell Division Outcome
Rushdia Z. Yusuf, David T. Scadden> ;Cell Metabolism. 2012 Oct 3
13 citations
The secrets of the bone marrow niche: Metabolic priming for AML
Rushdia Z. Yusuf, Ying-Hua Wang, David T. Scadden> ;Nature Medicine. 2012 Jun 6
215 citations
AKT/FOXO Signaling Enforces Reversible Differentiation Blockade in Myeloid Leukemias
Stephen M. Sykes, Steven W. Lane, Lars Bullinger, Demetrios Kalaitzidis, Rushdia Z. Yusuf, Borja Saez, Francesca Ferraro, Francois Mercier, Harshabad Singh, Kristina B...> ;Cell. 2011 Sep 2
The Lkb1 metabolic sensor maintains haematopoietic stem cell survival.
> ;Nature. 2011-07-06
138 citations
Inhibition of bone morphogenetic protein signaling attenuates anemia associated with inflammation.
Andrea U. Steinbicker, Chetana Sachidanandan, Ashley J. Vonner, Rushdia Z. Yusuf, Donna Y. Deng, Carol S. Lai, Kristen M. Rauwerdink, Julia C. Winn, Borja Saez, Collee...> ;Blood. 2011 May 5
302 citations
The Lkb1 metabolic sensor maintains haematopoietic stem cell survival
Sushma Gurumurthy, Stephanie Z. Xie, Brinda Alagesan, Judith Kim, Rushdia Z. Yusuf, Borja Saez, Alexandros Tzatsos, Fatih Ozsolak, Patrice M. Milos, Francesco Ferrari,...> ;Nature. 2010 Dec 2
11 citations
Homing of hematopoietic cells to the bone marrow.
Rushdia Z. Yusuf, David T. Scadden> ;Journal of Visualized Experiments. 2009 Mar 18
13 citations
Autologous SCT with a dose-reduced BU and CY regimen in older patients with non-Hodgkin's lymphoma.
Rushdia Z. Yusuf, Bimalangshu R. Dey, Beow Y. Yeap, Steven L. McAfee, Eyal C. Attar, Paul S. Sepe, Christine Dube, Thomas R. Spitzer, Karen K. Ballen> ;Bone Marrow Transplantation. 2009 Jan 1
46 citations
GBP1 overexpression is associated with a paclitaxel resistance phenotype.
Zhenfeng Duan, Rosemary Foster, Katherine A. Brakora, Rushdia Z. Yusuf, Michael V. Seiden> ;Cancer Chemotherapy and Pharmacology. 2006 Jan 1
67 citations
Description of paclitaxel resistance-associated genes in ovarian and breast cancer cell lines.
Zhenfeng Duan, Diana E. Lamendola, Yifei Duan, Rushdia Z. Yusuf, Michael V. Seiden> ;Cancer Chemotherapy and Pharmacology. 2005 Mar 1
30 citations
Cytogenetic abnormalities in products of conception: A relationship revisited
Rushdia Z. Yusuf, Rizwan Naeem> ;American Journal of Reproductive Immunology. 2004 Jul 1
36 citations
Utility of osteopontin as a biomarker in recurrent epithelial ovarian cancer.
Katherine A. Brakora, Hang Lee, Rushdia Z. Yusuf, L. Sullivan, Anne K. Harris, T Colella, Michael V. Seiden> ;Gynecologic Oncology. 2004 May 1
118 citations
Overexpression of MAGE/GAGE Genes in Paclitaxel/Doxorubicin-resistant Human Cancer Cell Lines
Zhenfeng Duan, Yifei Duan, Diana E. Lamendola, Rushdia Z. Yusuf, Rizwan Naeem, Richard T. Penson, Michael V. Seiden> ;Clinical Cancer Research. 2003 Jul 1
61 citations
Molecular Description of Evolving Paclitaxel Resistance in the SKOV-3 Human Ovarian Carcinoma Cell Line
Diana E. Lamendola, Zhenfeng Duan, Rushdia Z. Yusuf, Michael V. Seiden> ;Cancer Research. 2003 May 1
268 citations
Paclitaxel resistance: molecular mechanisms and pharmacologic manipulation.
Rushdia Z. Yusuf, Zhenfeng Duan, Diana E. Lamendola, Richard T. Penson, Michael V. Seiden> ;Current Cancer Drug Targets. 2003 Jan 31
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Hospital Affiliations

Dana-Farber Cancer InstituteBoston, Massachusetts
Brigham and Women's HospitalBoston, Massachusetts
Spaulding Hospital for Continuing Medical Care CambridgeCambridge, Massachusetts
Spaulding Rehabilitation HospitalCharlestown, Massachusetts
Cape Cod HospitalHyannis, Massachusetts

RushdiaZYusufMD

Dr. Yusuf is on Doximity

Education & Training

Certifications & Licensure

Publications & Presentations

Hospital Affiliations

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