JeffreyRennKeeferMD

PubMed

• 10 citations
  Clinical evaluation of combined azacitidine and entinostat on the induction of fetal hemoglobin in patients with acute myeloid leukemias and myelodysplastic syndromes.
  Katharine R. Press, Natalie Uy, Jeffrey R. Keefer, Steven D. Gore, Hetty E. Carraway, Sarah Sakoian, Thomas Prebet> ;Leukemia & Lymphoma. 2018 Mar 4
• 4 citations
  Identification of Aptamers That Bind to Sickle Hemoglobin and Inhibit Its Polymerization
  Shirley H. Purvis, Jeffrey R. Keefer, Yolanda M. Fortenberry, Emily Barron-Casella, James F. Casella> ;Nucleic Acid Therapeutics. 2017 Dec 1
• 85 citations
  Correction to A critical role for the host mediator macrophage migration inhibitory factor in the pathogenesis of malarial anemia [The Journal of Experimental Medicine...
  Michael A. McDevitt, Jianlin Xie, Shanmugasundaram Ganapathy-Kanniappan, Jason W. Griffith, Aihua Liu, Courtney McDonald, Philip E. Thuma, Victor R. Gordeuk, Christine...> ;The Journal of Experimental Medicine. 2015 May 4
• 15 citations
  Acute chest syndrome is associated with single nucleotide polymorphism-defined beta globin cluster haplotype in children with sickle cell anaemia.
  Christopher J. Bean, Sheree L. Boulet, Genyan Yang, Amanda B. Payne, Nafisa Ghaji, Meredith E. Pyle, W. Craig Hooper, Pallav Bhatnagar, Jeffrey R. Keefer, Emily Barron...> ;British Journal of Haematology. 2013 Oct 1
• 7 citations
  Association between baseline fetal hemoglobin levels and incidence of severe vaso-occlusive pain episodes in children with sickle cell anemia.
  Pallav Bhatnagar, Jeffrey R. Keefer, James F. Casella, Emily Barron-Casella, Christopher J. Bean, Craig Hooper, Amanda B. Payne, Dan E. Arking, Michael R. DeBaun> ;Pediatric Blood & Cancer. 2013 May 15
• 71 citations
  Sickle cell vaso-occlusion causes activation of iNKT cells that is decreased by the adenosine A2A receptor agonist regadenoson.
  Joshua J. Field, Gene Lin, Maureen Okam, Elaine M. Majerus, Jeffrey R. Keefer, Onyinye Onyekwere, Ainsley Ross, Federico Campigotto, Donna Neuberg, Joel Linden, David ...> ;Blood. 2013 Apr 25
• 22 citations
  A phase 1/2 trial of HQK-1001, an oral fetal globin inducer, in sickle cell disease
  Abdullah Kutlar, Kenneth I. Ataga, Marvin Reid, Elliott Vichinsky, Lynne Neumayr, Loray A Blair-Britt, Richard J. Labotka, Jonathan Glass, Jeffrey R. Keefer, William A...> ;American Journal of Hematology. 2012 Nov 1
• 9 citations
  A case study of a child with chronic hemolytic anemia due to a Donath-Landsteiner positive, IgM anti-I autoantibody.
  Matthew S. Karafin, R. Sue Shirey, Paul M. Ness, Karen E. King, Jeffrey R. Keefer> ;Pediatric Blood & Cancer. 2012 Nov 1
• 34 citations
  Activation of the stress proteome as a mechanism for small molecule therapeutics
  Rebecca Deering Brose, Gloria Shin, Martina C. McGuinness, Tonya Schneidereith, Shirley H. Purvis, Gao X. Dong, Jeffrey R. Keefer, Forrest Spencer, Kirby D. Smith> ;Human Molecular Genetics. 2012 Oct 1
• 63 citations
  Meta-analysis of 2040 sickle cell anemia patients: BCL11A and HBS1L-MYB are the major modifiers of HbF in African Americans
  Harold Bae, Clinton T. Baldwin, Paola Sebastiani, Marilyn J. Telen, Allison E. Ashley-Koch, Melanie E. Garrett, W. Craig Hooper, Christopher J. Bean, Michael R. DeBaun...> ;Blood. 2012 Aug 30
• 40 citations
  α-Thalassemia Impairs the Cytoadherence of Plasmodium falciparum-Infected Erythrocytes
  Michael Krause, Seidina A. S. Diakite, Tatiana M. Lopera-Mesa, Chanaki Amaratunga, Takayuki Arie, Karim Traore, Saibou Doumbia, Drissa Konaté, Jeffrey R. Keefer, Maham...> ;Plos One. 2012 May 18
• 5 citations
  Sickle cell disease (SCD), iNKT cells, and regadenoson infusion.
  David G. Nathan, Joshua J. Field, Gene Lin, Donna Neuberg, Elaine M. Majerus, Onyinye Onyekwere, Jeffrey R. Keefer, Maureen Okam, Ainsley Ross, Joel Linden> ;Transactions of the American Clinical and Climatological Association. 2012 Jan 1
• 19 citations
  Opioid patient controlled analgesia use during the initial experience with the IMPROVE PCA trial: a phase III analgesic trial for hospitalized sickle cell patients wit...
  Carlton Dampier, Wally R. Smith, Hae Young Kim, Carrie G. Wager, Margaret C. Bell, Caterina P. Minniti, Jeffrey R. Keefer, Lewis L. Hsu, Lakshmanan Krishnamurti, A. Ky...> ;American Journal of Hematology. 2011 Dec 1
• 21 citations
  Evaluation of Safety and Pharmacokinetics of Sodium 2,2 Dimethylbutyrate, a Novel Short Chain Fatty Acid Derivative, in a Phase 1, Double‐Blind, Placebo‐Controlled, Si...
  Susan P. Perrine, William A. Wargin, Michael S. Boosalis, Wayne Wallis, Sally Case, Jeffrey R. Keefer, Douglas V. Faller, William C. Welch, Ronald J. Berenson> ;Journal of Clinical Pharmacology. 2011 Aug 1
• 3 citations
  Subtotal splenic embolization is a safe and effective treatment for isolated splenic vascular tumors associated with consumptive coagulopathy
  Eric H. Raabe, Jeffrey R. Keefer, Sally E. Mitchell, Kelvin Hong, Marc DiFazio, John J. Strouse> ;Journal of Pediatric Hematology/oncology. 2011 Jul 1
• 57 citations
  A Role for Fetal Hemoglobin and Maternal Immune IgG in Infant Resistance to Plasmodium falciparum Malaria
  Chanaki Amaratunga, Tatiana M. Lopera-Mesa, Nathaniel J. Brittain, Rushina Cholera, Takayuki Arie, Hisashi Fujioka, Jeffrey R. Keefer, Rick M. Fairhurst> ;Plos One. 2011 Apr 12
• 62 citations
  Genome-wide association study identifies genetic variants influencing F-cell levels in sickle-cell patients.
  Pallav Bhatnagar, Shirley H. Purvis, Emily Barron-Casella, Michael R. DeBaun, James F. Casella, Dan E. Arking, Jeffrey R. Keefer> ;Journal of Human Genetics. 2011 Feb 17
• 17 citations
  Pediatric littoral cell angioma of the spleen: multimodality imaging including diffusion-weighted imaging.
  Gulhan Ertan, Aylin Tekes, Sally E. Mitchell, Jeffrey R. Keefer, Thierry A.G.M. Huisman> ;Pediatric Radiology. 2009 Jul 14
• 72 citations
  Corticosteroids and Increased Risk of Readmission After Acute Chest Syndrome in Children With Sickle Cell Disease
  John J. Strouse, Clifford M. Takemoto, Jeffrey R. Keefer, Gregory J. Kato, James F. Casella> ;Pediatric Blood & Cancer. 2008 May 1
• 63 citations
  C/EBPα:AP-1 leucine zipper heterodimers bind novel DNA elements, activate the PU.1 promoter and direct monocyte lineage commitment more potently than C/EBPα homodimers...
  D. H. Cai, Dehua Wang, Jeffrey R. Keefer, Christine Yeamans, Kortney Hensley, Alan D. Friedman> ;Oncogene. 2008 Apr 24
• 37 citations
  Role of cyclic nucleotides in fetal hemoglobin induction in cultured CD34+ cells.
  Jeffrey R. Keefer, Tonya Schneidereith, Abbie C. Mays, Shirley H. Purvis, George J. Dover, Kirby D. Smith> ;Experimental Hematology. 2006 Sep 1
• 84 citations
  A critical role for the host mediator macrophage migration inhibitory factor in the pathogenesis of malarial anemia.
  Michael A McDevitt, Jianlin Xie, Shanmugasundaram Ganapathy-Kanniappan, Ganapathy Shanmugasundaram, Jason Griffith, Aihua Liu, Courtney McDonald, Philip Thuma, Victor ...> ;The Journal of Experimental Medicine. 2006 May 15
• 44 citations
  Regulation of granulocyte and monocyte differentiation by CCAAT/enhancer binding protein α
  Alan D. Friedman, Jeffrey R. Keefer, Tanawan Kummalue, Huaitian Liu, Qianfei Wang, Rebecca Cleaves> ;Blood Cells, Molecules & Diseases. 2003 Nov 1
• 18 citations
  Reciprocal effects of C/EBPα and PKCδ on JunB expression and monocytic differentiation depend upon the C/EBPα basic region
  Huaitian Liu, Jeffrey R. Keefer, Qianfei Wang, Alan D. Friedman> ;Blood. 2003 May 15
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