JeremySettonMD

PubMed

• 4 citations
  Most large structural variants in cancer genomes can be detected without long reads.
  Zi-Ning Choo, Julie M Behr, Aditya Deshpande, Kevin Hadi, Xiaotong Yao, Huasong Tian, Kaori Takai, George Zakusilo, Joel Rosiene, Arnaud Da Cruz Paula, Britta Weigelt,...> ;Nature Genetics. 2023 Dec 1
• 3 citations
  Long-molecule scars of backup DNA repair in BRCA1- and BRCA2-deficient cancers.
  Jeremy Setton, Kevin Hadi, Zi-Ning Choo, Katherine S Kuchin, Huasong Tian, Arnaud Da Cruz Paula, Joel Rosiene, Pier Selenica, Julie Behr, Xiaotong Yao, Aditya Deshpand...> ;Nature. 2023 Sep 1
• 2 citations
  ATM Germline-Mutated Gastroesophageal Junction Adenocarcinomas: Clinical Descriptors, Molecular Characteristics, and Potential Therapeutic Implications.
  Tony El Jabbour, Maksym Misyura, Darren Cowzer, Michal Zimmermann, Victoria Rimkunas, Antonio Marra, Fatemeh Derakhshan, Pier Selenica, Megan Parilla, Jeremy S Setton,...> ;Journal of the National Cancer Institute. 2022 May 9
• 8 citations
  Germline RAD51B variants confer susceptibility to breast and ovarian cancers deficient in homologous recombination.
  Jeremy Setton, Pier Selenica, Semanti Mukherjee, Rachna Shah, Isabella Pecorari, Biko McMillan, Isaac X Pei, Yelena Kemel, Ozge Ceyhan-Birsoy, Margaret Sheehan, Kaitly...> ;NPJ Breast Cancer. 2021 Oct 11
• 60 citations
  Synthetic Lethality in Cancer Therapeutics: The Next Generation.
  Jeremy Setton, Michael Zinda, Nadeem Riaz, Daniel Durocher, Michal Zimmermann, Maria Koehler, Jorge S. Reis-Filho, Simon N. Powell> ;Cancer Discovery. 2021 Apr 1
• 10 citations
  Homologous recombination deficiency: how genomic signatures are generated.
  Jeremy Setton, Jorge S. Reis-Filho, S.N. Powell> ;Current Opinion in Genetics & Development. 2021 Feb 1
• 98 citations
  Mutations in BRCA1 and BRCA2 differentially affect the tumor microenvironment and response to checkpoint blockade immunotherapy
  Robert M. Samstein, Chirag Krishna, Xiaoxiao Ma, Xin Pei, Ken-Wing Lee, Vladimir Makarov, Fengshen Kuo, Jonathan H. Chung, Raghvendra M. Srivastava, Tanaya A. Purohit,...> ;Nature Cancer. 2020 Nov 16
• 106 citations
  Distinct Classes of Complex Structural Variation Uncovered across Thousands of Cancer Genome Graphs.
  Kevin Hadi, Xiaotong Yao, Julie M. Behr, Aditya Deshpande, Charalampos Xanthopoulakis, Huasong Tian, Sarah Kudman, Joel Rosiene, Madison Darmofal, Joseph DeRose, Rick ...> ;Cell. 2020 Oct 1
• 32 citations
  Pathogenic ATM Mutations in Cancer and a Genetic Basis for Radiotherapeutic Efficacy
  Kenneth L. Pitter, Dana L. Casey, Yue C Lu, Margaret Hannum, Zhigang Zhang, Xinmao Song, Isabella Pecorari, Biko McMillan, Jennifer Ma, Robert M. Samstein, Isaac X Pei...> ;Journal of the National Cancer Institute. 2021 Mar 1
• 1 citations
  Moving beyond PARP Inhibition in ATM-Deficient Prostate Cancer
  Jeremy Setton, Simon N. Powell> ;Cancer Research. 2020 Jun 1
• 17 citations
  The Landscape of Somatic Genetic Alterations in Breast Cancers from CHEK2 Germline Mutation Carriers.
  Diana Mandelker, Rajesh Kumar, Xin Pei, Pier Selenica, Jeremy Setton, Sasi Arunachalam, Ozge Ceyhan-Birsoy, David N Brown, Larry Norton, Mark E. Robson, Hannah Y Wen, ...> ;JNCI Cancer Spectrum. 2019 Apr 27
• 126 citations
  The therapeutic significance of mutational signatures from DNA repair deficiency in cancer
  Jennifer Ma, Jeremy Setton, Nancy Y. Lee, Nadeem Riaz, Simon N. Powell> ;Nature Communications. 2018 Aug 17
• A new role for a tumor-suppressing protein.
  Jeremy Setton, Simon N. Powell> ;Elife. 2018 Mar 1
• 8 citations
  Modeling Dose Response for Late Dysphagia in Patients With Head and Neck Cancer in the Modern Era of Definitive Chemoradiation
  Chiaojung Jillian Tsai, Andrew Jackson, Jeremy Setton, Nadeem Riaz, Sean McBride, Jonathan E. Leeman, Alex Kowalski, Laura Happersett, Nancy Y. Lee> ;JCO Clinical Cancer Informatics. 2017 Nov 7
• 40 citations
  Predictive modeling of outcomes following definitive chemoradiotherapy for oropharyngeal cancer based on FDG-PET image characteristics
  Michael R. Folkert, Jeremy Setton, Aditya Apte, Milan Grkovski, Robert J. Young, Heiko Schöder, Wade L. Thorstad, Nancy Y. Lee, Joseph O. Deasy, Jung Hun Oh> ;Physics in Medicine and Biology. 2017 Jun 12
• 26 citations
  Genomic analysis of exceptional responders to radiotherapy reveals somatic mutations in ATM.
  Jennifer Ma, Jeremy Setton, Luc G. T. Morris, Pedro Blecua Carrillo Albornoz, Christopher A. Barker, Benjamin H. Lok, Eric J. Sherman, Nora Katabi, Kathryn Beal, Ian G...> ;Oncotarget. 2017 Feb 7
• 15 citations
  Patterns of nodal failure after intensity modulated radiotherapy for nasopharyngeal carcinoma.
  Jin-Gao Li, Praveen Venigalla, Jonathan E. Leeman, Quincey LaPlant, Jeremy Setton, Eric J. Sherman, Jillian Tsai, Sean McBride, Nadeem Riaz, Nancy Y. Lee> ;The Laryngoscope. 2017 Feb 1
• 39 citations
  Long-term patterns of relapse and survival following definitive intensity-modulated radiotherapy for non-endemic nasopharyngeal carcinoma
  Jeremy Setton, James Han, D. Kannarunimit, Yen-Ruh Wuu, Stephen A. Rosenberg, Carl J. DeSelm, Suzanne L. Wolden, C. Jillian Tsai, Sean McBride, Nadeem Riaz, Nancy Y. Lee> ;Oral Oncology. 2016 Feb 1
• 30 citations
  Dose-volume factors correlating with trismus following chemoradiation for head and neck cancer
  Shyam Rao, Ziad Saleh, Jeremy Setton, Moses Tam, Sean McBride, Nadeem Riaz, Joseph O. Deasy, Nancy Y. Lee> ;Acta Oncologica. 2016 Jan 2
• 95 citations
  A multi-institution pooled analysis of gastrostomy tube dependence in patients with oropharyngeal cancer treated with definitive intensity-modulated radiotherapy.
  Jeremy Setton, Nancy Y. Lee, Nadeem Riaz, Shao Hui Huang, John Waldron, Brian O'Sullivan, Zhigang Zhang, Weij Shi, David I. Rosenthal, Katherine A. Hutcheson, Adam S. ...> ;Cancer. 2015 Jan 15
• 43 citations
  Efficacy of concurrent cetuximab vs. 5-fluorouracil/carboplatin or high-dose cisplatin with intensity-modulated radiation therapy (IMRT) for locally-advanced head and ...
  Lauren Q. Shapiro, Eric J. Sherman, Nadeem Riaz, Jeremy Setton, Lawrence Koutcher, Zhigang Zhang, Weiji Shi, Matthew G. Fury, Suzanne L. Wolden, David G. Pfister, Luc ...> ;Oral Oncology. 2014 Oct 1
• 16 citations
  Patients with low lying lymph nodes are at high risk for distant metastasis in oropharyngeal cancer
  Nadeem Riaz, Jeremy Setton, Moses Tam, Eric J. Sherman, Felix Ho, Evangelia Katsoulakis, Richard J. Wong, Suzanne L. Wolden, Shyam Rao, Nancy Y. Lee> ;Oral Oncology. 2014 Sep 1
• 31 citations
  The relative prognostic utility of standardized uptake value, gross tumor volume, and metabolic tumor volume in oropharyngeal cancer patients treated with platinum bas...
  Paul B. Romesser, Remy Lim, Daniel E. Spratt, Jeremy Setton, Nadeem Riaz, Benjamin H. Lok, Shyam Rao, Eric J. Sherman, Heiko Schöder, Nancy Y. Lee> ;Oral Oncology. 2014 Sep 1
• 24 citations
  Estimate of the impact of FDG-avidity on the dose required for head and neck radiotherapy local control.
  J Jeong, Jeremy Setton, Nancy Y. Lee, Jung Hun Oh, Joseph O. Deasy> ;Radiotherapy and Oncology. 2014 Jun 1
• 31 citations
  Long‐term regional control in the observed neck following definitive chemoradiation for node‐positive oropharyngeal squamous cell cancer
  Anuj Goenka, Luc G. T. Morris, Shyam Rao, Suzanne L. Wolden, Richard J. Wong, Dennis H. Kraus, Nisha Ohri, Jeremy Setton, Benjamin H. Lok, Nadeem Riaz, Borys Mychalcza...> ;International Journal of Cancer. 2013 Sep 1
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