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John Byrd, MD, Hematology, Pittsburgh, PA

John C. Byrd MD

Hematologic Oncology, Myeloproliferative Disorder Hematology-Oncology, Clinical Pharmacology


Chair and Professor, Department of Internal Medicine

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  • 5150 Centre AveFl 5Pittsburgh, PA 15232

  • Phone+1 412-623-3205

  • Fax+1 513-584-6955

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Summary

  • I am currently Chair, Department of Internal Medicine at the University of Cincinnati and also a physician scientist who has done translational and clinical drug development for two decades. Closest to me professional being is performing as an exceptional, empathetic board certified hematologist in care of patients with blood cancers. My laboratory and clinical research has directly resulted in 7 drugs getting FDA approval. This experience bridges close interaction with industry as a consultant to develop and implement a successful development plan (Calistoga, Idelalisib) to performing pre-clinical and clinical work in my University role focused on a single class of drugs that transformed the care of CLL (Ibrutinib, Acalabrutinib) and other B-cell malignancies. My role in the current Leukemia and Lymphoma Society Beat AML Study as Principal and Chief Medical Officer has offered an even larger extension of this by planning, implementing, and running a multi-center umbrella study in AML that brings together academic clinical investigators, diagnostic companies, pharmaceutical companies, clinical research organizations and the FDA to effectively move new therapies forward to the clinic.

Education & Training

  • National Capital Consortium
    National Capital ConsortiumFellowship, Hematology and Medical Oncology, 1994 - 1997
  • National Capital Consortium (Walter Reed)
    National Capital Consortium (Walter Reed)Residency, Internal Medicine, 1991 - 1994
  • University of Arkansas For Medical Sciences College of Medicine
    University of Arkansas For Medical Sciences College of MedicineClass of 1991
  • Hendrix College
    Hendrix CollegeB.A., Chemistry, With distinction, 1987

Certifications & Licensure

  • OH State Medical License
    OH State Medical License 2001 - 2027
  • PA State Medical License
    PA State Medical License 2025 - 2026
  • VA State Medical License
    VA State Medical License 1993 - 2020
  • Hematology
    American Board of Internal Medicine Hematology

Awards, Honors, & Recognition

  • Return of the Child Award Leukemia and Lymphoma Society, 2017
  • Fellow American College of Physicians, 2017
  • CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory - Core EMR, Epic Systems Corporation, 2012, 2014, 2016-2017

Clinical Trials

Publications & Presentations

PubMed

Journal Articles

  • Non-Hodgkin’s lymphomas  
    Zelenetz AD, Abramson JS, Advani RH, Andreadis B, Bartlett N, Bellam N, Byrd JC, Czuczman MS, Fayad LE, Glenn MJ, Gockerman JP, Gordon LI, Harris NL, Hoppe RT, Horwitz..., J Natl Compr Canc Netw, 1/1/2011
  • Zn2+-chelating motif-tethered short-chain fatty acids as a novel class of histone deacetylase inhibitors  
    Lu Q, Yang YT, Chen CS, Davis M, Byrd JC, Etherton MR, Umar A, Chen CS, J Med Chemistry, 1/15/2004
  • Coxsackievirus-associated pancreatitis mimicking metastatic carcinoma  
    Gooby Toedt DM, Byrd JC, Omori D, South Med J, 1/1/1996

Press Mentions

  • UPMC Hillman Cancer Center Completes Extensive Renovations Supported by the Lemieux Foundation and Chris and Bob Pietrandrea
    UPMC Hillman Cancer Center Completes Extensive Renovations Supported by the Lemieux Foundation and Chris and Bob PietrandreaNovember 13th, 2025
  • Combination Therapy Offers Hope for Ending Lifelong Chronic Lymphocytic Leukemia Treatment
    Combination Therapy Offers Hope for Ending Lifelong Chronic Lymphocytic Leukemia TreatmentNovember 5th, 2025
  • John C. Byrd, MD
    John C. Byrd, MDOctober 20th, 2025

Grant Support

  • Pharmacodynamically directed targeted therapy for leukemiaUNIVERSITY OF CINCINNATI2025–2030
  • ITSC for Leukemia: Novel Molecular strategies for NCTN "Individualized" TherapiesUNIVERSITY OF CINCINNATI2019–2026
  • NCI ETCTN Pittsburgh Cancer Consortium (PCC)UNIVERSITY OF PITTSBURGH AT PITTSBURGH2014–2026
  • Lenalidomide As An Immune Modulating Agent For Chronic Lymphocytic LeukemiaNational Cancer Institute2009–2011
  • Experimental Therapeutics Of LeukemiaNational Cancer Institute2009–2011

Professional Memberships

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