JohnRobertFerraroneMD

PubMed

• 3 citations
  LKB1-Dependent Regulation of TPI1 Creates a Divergent Metabolic Liability between Human and Mouse Lung Adenocarcinoma.
  Benjamin D Stein, John R Ferrarone, Eric E Gardner, Jae Won Chang, David Wu, Pablo E Hollstein, Roger J Liang, Min Yuan, Qiuying Chen, John S Coukos, Miriam Sindelar, ...> ;Cancer Discovery. 2023 Apr 3
• 12 citations
  Characterization of a small molecule inhibitor of disulfide reductases that induces oxidative stress and lethality in lung cancer cells.
  Fraser D Johnson, John Ferrarone, Alvin Liu, Christina Brandstädter, Ravi Munuganti, Dylan A Farnsworth, Daniel Lu, Jennifer Luu, Tianna Sihota, Sophie Jansen, Amy Nag...> ;Cell Reports. 2022 Feb 8
• 17 citations
  GCN2 kinase activation by ATP-competitive kinase inhibitors.
  Colin P Tang, Owen Clark, John R Ferrarone, Carl Campos, Alshad S Lalani, John D Chodera, Andrew M Intlekofer, Olivier Elemento, Ingo K Mellinghoff> ;Nature Chemical Biology. 2022 Feb 1
• 56 citations
  Hyperactivation of ERK by multiple mechanisms is toxic to RTK-RAS mutation-driven lung adenocarcinoma cells.
  Arun M. Unni, Bryant T. Harbourne, Min Hee Oh, Sophia A Wild, John Ferrarone, William W. Lockwood, Harold E. Varmus> ;Elife. 2018 Nov 26
• 53 citations
  Impaired hematopoiesis and leukemia development in mice with a conditional knock-in allele of a mutant splicing factor gene U2af1
  Dennis Liang Fei, Tao Zhen, Benjamin H. Durham, John Ferrarone, Tuo Zhang, Lisa Garrett, Akihide Yoshimi, Omar Abdel-Wahab, Robert K. Bradley, Paul P. Liu, Harold E. V...> ;Proceedings of the National Academy of Sciences of the United States of America. 2018 Oct 30
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Journal Articles

• Impaired Hematopoiesis and Leukemia Development in Mice with a Conditional Knock-in Allele of a Mutant Splicing Factor Gene U2af1  
  John Ferrarone, MD, Proceedings of the National Academy of Sciences